Complex segregation analysis of non-myoclonic idiopathic: Generalized epilepsy in families ascertained from probands affected with idiopathic epilepsy with tonic-clonic seizures in Antioquia, Colombia

Human Genetics

Volumn 98, Issue 2, 1996, Pages 214-218

  Jiménez, Iván ^a   Mora, Ofelia ^a   Jiménez, Martha ^a   Zuluaga, Luz ^a   Isaza, Rodrigo ^a   Sánchez, Jorge L ^a   Uribe, Carlos S ^a   Blanco, Rafael ^b   Arcos Burgos, Mauricio ^a  

^a Antioquian League Against Epilepsy   (Colombia)

^b UNIVERSITY OF CHILE   (Chile)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; CODOMINANCE; COLOMBIA; EPILEPSY; GENE LOCUS; GENETIC EPISTASIS; HUMAN; MULTIFACTORIAL INHERITANCE; PRIORITY JOURNAL; SEGREGATION ANALYSIS; TONIC SEIZURE;

ALLELES; CLUSTER ANALYSIS; COLOMBIA; EPILEPSY, GENERALIZED; EPILEPSY, TONIC-CLONIC; FEMALE; GENES, DOMINANT; HETEROZYGOTE; HUMANS; MALE; MODELS, GENETIC;

EID: 0030006416     PISSN: 03406717     EISSN: None     Source Type: Journal    
DOI: 10.1007/s004390050194     Document Type: Article

References (28)

1. Agudelo LE (1986) Bogotá DE (ed) Génesis del Pueblo Antioqueño. Era Cósmica, Colombia
2. Anderson VE, Hauser WA, Rich SS (1986) Genetic heterogeneity in the epilepsies. Adv Neurol 44:59-75
3. Arcos OM, Bravo ML (1992) Epidemiologìa genética de hendidura facial no sindromática en la población de Antioquia. Universidad de Antioquia, Medellín, Colombia, W575.293A 675C(S.N.) Access 069241
4. Commission on the classification and terminology of the International League Against Epilepsy (1989) Proposal for the revised classification of epilepsies and epileptic syndromes. Epilepsia 30:389-399
5. Degen R (1978) Epilepsy in children. An etiological study based on their obstetrical record. J Neurol 217:145-158
6. Delgado Escueta AV, Greenberg DA, Weisshecker K, Liu A, Treiman L, Sparkes R, Park MS, Barbetti A, Terasaki PI (1990) Gene mapping in the idiopathic generalized epilepsies: juvenile myoclonic epilepsy, childhood absence epilepsy, epilepsy with grand mal seizures, and early childhood myoclonic epilepsy. Epilepsia 3 1[Suppl 3]: S19-S29
7. Durner M, Sander T, Greenberg DA, Johnson K, Beck-Mannagetta G, Janz D (1991) Localization of idiopathic generalized epilepsy on chromosome 6p in families of juvenile myoclonic epilepsy patients. Neurology 41:1651-1655
8. Farrer LA, Myers RH, Connor L, Cupples A, Growdon JH (1991) Segregation analysis reveals evidence of a major gene for Alzheimer's disease. Am J Hum Genet 48:1026-1033
9. Gómez JR, Bravo ML (1985) Estudio de la estructura genética de la población de el Santuario Antioquia. Universidad de Antioquia, Medellín, Colombia, 93H W575.12 G633E Access 046359
10. Greenberg DA, Delgado-Escueta AV (1993) The chromosome 6p epilepsy locus: exploring mode of inheritance and heterogeneity through linkage analysis. Epilepsia 34 [Suppl 3]:S12-S18
11. Hodge SE, Greenberg DA, Durner M (1989) Is juvenile myoclonic epilepsy polygenic? In: Beck-Mannagetta G, Anderson VE, Doose H, Janz D (eds) Genetics of the epilepsies. Springer, Berlin Heidelberg New York, pp 62-66
12. Hurst R, Lenn NJ (1986) Partial seizures in monozygous twins. Epilepsia 27:121-123
13. Italian League Against Epilepsy Genetic Collaborative Group (1993) Concordance of clinical forms of epilepsy in families with several affected members. Epilepsia 34:819-826
14. Jiménez I, Uribe CS, Mejía W (1984) Prevalencia de la epilepsia en Medellín. Acta Med Colombiana 9 [Suppl 5] :60
15. Jiménez I, Mora O, Zuluaga L, Sanchez J, Uribe CS, Isaza R, Cornejo W (1991) Factores de riesgo en epilepsia. Estudio de casos y controles. Acta Med Colombiana 16:5-17
16. Lalouel JM, Morton NE (1981) Complex segregation analysis with pointers. Hum Hered 31:312-321
17. Lalouel JM, Rao DC, Morton NE, Elston RC (1983) A unified model for complex segregation analysis. Am J Hum Genet 35:816-826
18. MacLean CJ, Morton NE, Lew R (1975) Analysis of family resemblance. IV. Operational characteristics of segregation analysis. Am J Hum Genet 27:365-384
19. Mesa D (1988) Bogota DE (ed) Polémica sobre el origen del pueblo Antioqueño. Fondo Cultural Cafetero, Colombia
20. Morton NE (1959) Genetic tests under incomplete ascertainment.Am J Hum Genet 11:1-16
21. Panayiotopoulos CP, Obeid T (1989) Juvenile myclonic epilepsy: an autosomal recessive disease. Ann Neurol 25:440-142
22. Parsons JJ (1949) Antioqueno colonization in western Colombia. University of California Press, Berkeley
23. Sander JWAS, Shorvon SD (1987) Incidence and prevalence studies in epilepsy and their methodological problems: a review. J Neurol Neurosurg Psychiatry 50:829-839
24. Shorvon SD, Farmer PJ (1988) Epilepsy in developing countries: a review of epidemiological, sociocultural, and treatment aspects. Epilepsia 29 [Suppl 1]:S36-S54
25. Simpson SP (1983) Estimating the ascertainment probability from the number of ascertainments per proband. Hum Hered 33:103-108
26. Tsuboi T, Christian W (1973) On the genetics of primary generalized epilepsy with sporadic myoclonias of impulsive petit mal. A clinical and electroencephalographic study of 399 probands. Hum Genet 19:155-182
27. Tsuboi T (1976) Polygenic inheritance of epilepsy and febrile convulsions: analysis based on a computational model. Br J Psychiatry 129:239-242
28. Zuluaga L, Soto C (1986) Prevalencia de la epilepsia en la ciudad de Medellín. Boletín de la Oficina Sanitaria Panamericana 104: (4):331-343