메뉴 건너뛰기




Volumn 4, Issue 4, 1999, Pages 323-332

Responsiveness of vascular endothelium to shear stress: Potential role of ion channels and cellular cytoskeleton (Review)

Author keywords

Atherosclerosis; Endothelium; Hemodynamics; Mechanotransduction; Shear stress

Indexed keywords

CELL ADHESION MOLECULE; ENDOTHELIN 1; GUANINE NUCLEOTIDE BINDING PROTEIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; ION CHANNEL; NITRIC OXIDE SYNTHASE; PLATELET DERIVED GROWTH FACTOR A; PLATELET DERIVED GROWTH FACTOR B; PROTEIN TYROSINE KINASE; TRANSCRIPTION FACTOR AP 1; TRANSFORMING GROWTH FACTOR BETA1; VASCULAR CELL ADHESION MOLECULE 1;

EID: 0033208594     PISSN: 11073756     EISSN: 1791244X     Source Type: Journal    
DOI: 10.3892/ijmm.4.4.323     Document Type: Article
Times cited : (70)

References (108)
  • 1
    • 0029072762 scopus 로고
    • Flow-mediated endothelial mechanotransduction
    • Davies PF: Flow-mediated endothelial mechanotransduction. Physiol Rev 75: 519-560, 1995.
    • (1995) Physiol Rev , vol.75 , pp. 519-560
    • Davies, P.F.1
  • 2
    • 0027529593 scopus 로고
    • Mechanical stress mechanisms and the cell: An endothelial paradigm
    • Davies PF and Tripathi SC: Mechanical stress mechanisms and the cell: an endothelial paradigm. Circ Res 72: 239-245, 1993.
    • (1993) Circ Res , vol.72 , pp. 239-245
    • Davies, P.F.1    Tripathi, S.C.2
  • 3
    • 0031857772 scopus 로고    scopus 로고
    • Mechanisms of shear stress transmission and transduction in endothelial cells
    • Barakat AI and Davies PF: Mechanisms of shear stress transmission and transduction in endothelial cells. Chest 114: 58S-63S, 1998.
    • (1998) Chest , vol.114 , pp. 58S-63S
    • Barakat, A.I.1    Davies, P.F.2
  • 5
    • 0029132731 scopus 로고
    • Hemodynamic forces are complex regulators of endothelial gene expression
    • Resnick N and Gimbrone MA Jr. Hemodynamic forces are complex regulators of endothelial gene expression. FASEB J 9: 874-882, 1995.
    • (1995) FASEB J , vol.9 , pp. 874-882
    • Resnick, N.1    Gimbrone, M.A.2
  • 6
    • 0028040352 scopus 로고
    • Molecular aspects of signal transduction of shear stress in the endothelial cell
    • Malek AM and Izumo S: Molecular aspects of signal transduction of shear stress in the endothelial cell. J Hypertens 12: 989-999, 1994.
    • (1994) J Hypertens , vol.12 , pp. 989-999
    • Malek, A.M.1    Izumo, S.2
  • 7
    • 0031833126 scopus 로고    scopus 로고
    • Laminar shear stress - Mechanisms by which endothelial cells transduce an atheroprotective force
    • Traub O and Berk BC: Laminar shear stress - Mechanisms by which endothelial cells transduce an atheroprotective force. Arterioscler Thromb Vase Biol 18: 677-685, 1998.
    • (1998) Arterioscler Thromb Vase Biol , vol.18 , pp. 677-685
    • Traub, O.1    Berk, B.C.2
  • 8
    • 0022590909 scopus 로고
    • Crucial role of endothelium in the vasodilator response to increased flow in vivo
    • Pohl U, Holtz J, Busse R and Bassenge E: Crucial role of endothelium in the vasodilator response to increased flow in vivo. Hypertension 8: 37-47, 1986.
    • (1986) Hypertension , vol.8 , pp. 37-47
    • Pohl, U.1    Holtz, J.2    Busse, R.3    Bassenge, E.4
  • 9
    • 0022587290 scopus 로고
    • Reductions in arterial diameter produced by chronic decreases in blood flow are endotheliumdependent
    • Langille BL and O'Donnell F: Reductions in arterial diameter produced by chronic decreases in blood flow are endotheliumdependent. Science 231: 405-407, 1986.
    • (1986) Science , vol.231 , pp. 405-407
    • Langille, B.L.1    O'Donnell, F.2
  • 10
    • 0026911059 scopus 로고
    • Vascular fluid mechanics, the arterial wall, and atherosclerosis
    • Nerem RM: Vascular fluid mechanics, the arterial wall, and atherosclerosis. J Biomech Eng 114: 274-282, 1992.
    • (1992) J Biomech Eng , vol.114 , pp. 274-282
    • Nerem, R.M.1
  • 11
    • 0020623530 scopus 로고
    • Pulsatile flow in a model carotid bifurcation
    • Ku DN and Giddens DP: Pulsatile flow in a model carotid bifurcation. Arteriosclerosis 3: 31-39, 1983.
    • (1983) Arteriosclerosis , vol.3 , pp. 31-39
    • Ku, D.N.1    Giddens, D.P.2
  • 12
    • 0021966255 scopus 로고
    • Pulsatile flow and atherosclerosis in the human carotid bifurcation. Positive correlation between plaque location and low and oscillating shear stress
    • Ku DN, Giddens DP, Zarins CK and Glagov S: Pulsatile flow and atherosclerosis in the human carotid bifurcation. Positive correlation between plaque location and low and oscillating shear stress. Arteriosclerosis 5: 293-301, 1985.
    • (1985) Arteriosclerosis , vol.5 , pp. 293-301
    • Ku, D.N.1    Giddens, D.P.2    Zarins, C.K.3    Glagov, S.4
  • 13
    • 0028837365 scopus 로고
    • Calcium responses of endothelial cell monolayers subjected to pulsatile and steady laminar flow differ
    • Helmlinger G, Berk BC and Nerem RM: Calcium responses of endothelial cell monolayers subjected to pulsatile and steady laminar flow differ. Am J Physiol 269: C367-C375, 1995.
    • (1995) Am J Physiol , vol.269 , pp. C367-C375
    • Helmlinger, G.1    Berk, B.C.2    Nerem, R.M.3
  • 15
    • 0025770579 scopus 로고
    • Effects of pulsatile flow on cultured vascular endothelial cell morphology
    • Helmlinger G, Geiger RV, Schreck S and Nerem RM: Effects of pulsatile flow on cultured vascular endothelial cell morphology. J Biomech Eng 113: 123-134, 1991.
    • (1991) J Biomech Eng , vol.113 , pp. 123-134
    • Helmlinger, G.1    Geiger, R.V.2    Schreck, S.3    Nerem, R.M.4
  • 16
    • 84943425074 scopus 로고    scopus 로고
    • Effect of different forms of shear stress on TGF-ßl mRNA expression in endothelial cells
    • Barakat AI, Lum RM, Withers GE and Wiley LM: Effect of different forms of shear stress on TGF-ßl mRNA expression in endothelial cells. FASEB J 12: A855, 1999.
    • (1999) FASEB J , vol.12 , pp. A855
    • Barakat, A.I.1    Lum, R.M.2    Withers, G.E.3    Wiley, L.M.4
  • 17
    • 0032559834 scopus 로고    scopus 로고
    • Oscillatory shear stress stimulates adhesion molecule expression in cultured human endothelium
    • Chappell DC, Varner SE, Nerem RM, Medförd RM and Alexander RW: Oscillatory shear stress stimulates adhesion molecule expression in cultured human endothelium. Circ Res 82: 532-539, 1998.
    • (1998) Circ Res , vol.82 , pp. 532-539
    • Chappell, D.C.1    Varner, S.E.2    Nerem, R.M.3    Medförd, R.M.4    Alexander, R.W.5
  • 18
    • 0031806789 scopus 로고    scopus 로고
    • Influence of oscillatory and unidirectional flow environments on the expression of endothelin and nitric oxide synthase in cultured endothelial cells
    • Ziegler T, Bouzourene K, Harrison VJ, Brunner HR and Hayoz D: Influence of oscillatory and unidirectional flow environments on the expression of endothelin and nitric oxide synthase in cultured endothelial cells. Arterioscler Thromb Vase Biol 18: 686-692, 1998.
    • (1998) Arterioscler Thromb Vase Biol , vol.18 , pp. 686-692
    • Ziegler, T.1    Bouzourene, K.2    Harrison, V.J.3    Brunner, H.R.4    Hayoz, D.5
  • 19
    • 0027221483 scopus 로고
    • Cellular tensegrity: Defining new rules of biological design that govern the cytoskeleton
    • Ingber DE: Cellular tensegrity: defining new rules of biological design that govern the cytoskeleton. J Cell Sei 104: 613-627, 1993.
    • (1993) J Cell Sei , vol.104 , pp. 613-627
    • Ingber, D.E.1
  • 20
    • 0028282547 scopus 로고
    • Cellular tensegrity: Exploring how mechanical changes in the cytoskeleton regulate cell growth, migration, and tissue pattern during morphogenesis
    • Ingber DE, Dike L, Hansen L, Karp S, Liley H, Maniotis A, McNamee H, Mooney D, Plopper G, Sims J and Wang N: Cellular tensegrity: exploring how mechanical changes in the cytoskeleton regulate cell growth, migration, and tissue pattern during morphogenesis. Int Rev Cytol 150: 173-224, 1994.
    • (1994) Int Rev Cytol , vol.150 , pp. 173-224
    • Ingber, D.E.1    Dike, L.2    Hansen, L.3    Karp, S.4    Liley, H.5    Maniotis, A.6    McNamee, H.7    Mooney, D.8    Plopper, G.9    Sims, J.10    Wang, N.11
  • 21
  • 23
    • 0029399233 scopus 로고
    • Determination of wall shear stress in the aorta with the use of MR phase velocity mapping
    • Oshinski JN, Ku DN, Mukundan S Jr, Loth F and Pettigrew RI: Determination of wall shear stress in the aorta with the use of MR phase velocity mapping. J Magn Reson Imaging 5: 640-647, 1995.
    • (1995) J Magn Reson Imaging , vol.5 , pp. 640-647
    • Oshinski, J.N.1    Ku, D.N.2    Mukundan, S.3    Loth, F.4    Pettigrew, R.I.5
  • 24
    • 0031830533 scopus 로고    scopus 로고
    • Visualizing blood flow patterns using streamlines, arrows, and particle paths
    • Buonocore MH: Visualizing blood flow patterns using streamlines, arrows, and particle paths. Magn Reson Med 40: 210-226, 1998.
    • (1998) Magn Reson Med , vol.40 , pp. 210-226
    • Buonocore, M.H.1
  • 25
    • 0026911048 scopus 로고
    • Pulsatile flow visualization in the abdominal aorta under differing physiologic conditions: Implications for increased susceptibility to atherosclerosis
    • Moore JE, Ku DN, Zarins CK and Glagov S: Pulsatile flow visualization in the abdominal aorta under differing physiologic conditions: implications for increased susceptibility to atherosclerosis. J Biomech Eng 114: 391-397, 1991.
    • (1991) J Biomech Eng , vol.114 , pp. 391-397
    • Moore, J.E.1    Ku, D.N.2    Zarins, C.K.3    Glagov, S.4
  • 26
    • 0026908624 scopus 로고
    • Pulsatile flow visualization in a model of the human abdominal aorta and aortic bifurcation
    • Pedersen EM, Yoganathan AP and Lefebvre XP: Pulsatile flow visualization in a model of the human abdominal aorta and aortic bifurcation. J Biomech 25: 935-944, 1992.
    • (1992) J Biomech , vol.25 , pp. 935-944
    • Pedersen, E.M.1    Yoganathan, A.P.2    Lefebvre, X.P.3
  • 28
    • 0016484777 scopus 로고
    • Localization of early atherosclerotic lesions in the aortic arch in the light of fluid flow
    • Rodkiewicz CM: Localization of early atherosclerotic lesions in the aortic arch in the light of fluid flow. J Biomech 8: 149-156, 1975.
    • (1975) J Biomech , vol.8 , pp. 149-156
    • Rodkiewicz, C.M.1
  • 29
    • 0023286598 scopus 로고
    • Correlation among shear rate measures in vascular flows
    • Friedman MH and Deters OJ: Correlation among shear rate measures in vascular flows. J Biomech Eng 109: 25-26, 1987.
    • (1987) J Biomech Eng , vol.109 , pp. 25-26
    • Friedman, M.H.1    Deters, O.J.2
  • 31
    • 0029294482 scopus 로고
    • The effect of pulsatile frequency on wall shear in a compliant cast of a human aortic bifurcation
    • Kuban BD and Friedman MH: The effect of pulsatile frequency on wall shear in a compliant cast of a human aortic bifurcation. J Biomech Eng 117: 219-223, 1995.
    • (1995) J Biomech Eng , vol.117 , pp. 219-223
    • Kuban, B.D.1    Friedman, M.H.2
  • 32
    • 0025247921 scopus 로고
    • Flow patterns and spatial distribution of atherosclerotic lesions in human coronary arteries
    • Asakura T and Karino T: Flow patterns and spatial distribution of atherosclerotic lesions in human coronary arteries. Circ Res 66: 1045-1066, 1990.
    • (1990) Circ Res , vol.66 , pp. 1045-1066
    • Asakura, T.1    Karino, T.2
  • 33
    • 0030670887 scopus 로고    scopus 로고
    • Microcinematographic studies of the flow field in the excised rabbit aorta and its major branches
    • Barakat AI, Karino T and Colton CK: Microcinematographic studies of the flow field in the excised rabbit aorta and its major branches. Biorheology 34: 195-221, 1997.
    • (1997) Biorheology , vol.34 , pp. 195-221
    • Barakat, A.I.1    Karino, T.2    Colton, C.K.3
  • 34
    • 0025353535 scopus 로고
    • Flow patterns at the major T-junctions of the dog descending aorta
    • Karino T, Motomiya M and Goldsmith HL: Flow patterns at the major T-junctions of the dog descending aorta. J Biomech 23: 537-548, 1990.
    • (1990) J Biomech , vol.23 , pp. 537-548
    • Karino, T.1    Motomiya, M.2    Goldsmith, H.L.3
  • 35
    • 84943416630 scopus 로고    scopus 로고
    • Computational study of the effect of geometric and flow parameters on the steady flow field at the rabbit aorto-celiac bifurcation
    • (In press)
    • Cheer AY, Dwyer HA, Barakat AI, Sy E and Bice M: Computational study of the effect of geometric and flow parameters on the steady flow field at the rabbit aorto-celiac bifurcation. Biorheology (In press).
    • Biorheology
    • Cheer, A.Y.1    Dwyer, H.A.2    Barakat, A.I.3    Sy, E.4    Bice, M.5
  • 36
    • 0029347554 scopus 로고
    • Numerical investigation and prediction of atherogenic sites in branching arteries
    • Lei M, Kleinstreuer C and Truskey GA: Numerical investigation and prediction of atherogenic sites in branching arteries. J Biomech Eng 117: 350-357, 1995.
    • (1995) J Biomech Eng , vol.117 , pp. 350-357
    • Lei, M.1    Kleinstreuer, C.2    Truskey, G.A.3
  • 37
    • 0023752868 scopus 로고
    • Wall shear stress distribution in the human carotid siphon during pulsatile flow
    • Perktold K, Florian H, Hilbert D and Peter R: Wall shear stress distribution in the human carotid siphon during pulsatile flow. J Biomech 21: 663-671, 1988.
    • (1988) J Biomech , vol.21 , pp. 663-671
    • Perktold, K.1    Florian, H.2    Hilbert, D.3    Peter, R.4
  • 38
    • 0029329172 scopus 로고
    • Computer simulation of local blood flow and vessel mechanics in a compliant carotid artery bifurcation model
    • Perktold K and Rappitsch G: Computer simulation of local blood flow and vessel mechanics in a compliant carotid artery bifurcation model. J Biomech 28: 845-856, 1995.
    • (1995) J Biomech , vol.28 , pp. 845-856
    • Perktold, K.1    Rappitsch, G.2
  • 39
    • 0025315844 scopus 로고
    • A numerical analysis of steady flow in a threedimensional model of the carotid artery bifurcation
    • Rindt CC, van Steenhoven AA, Janssen JD, Reneman RS and Segal A: A numerical analysis of steady flow in a threedimensional model of the carotid artery bifurcation. J Biomech 23: 461-473, 1990.
    • (1990) J Biomech , vol.23 , pp. 461-473
    • Rindt, C.C.1    Van Steenhoven, A.A.2    Janssen, J.D.3    Reneman, R.S.4    Segal, A.5
  • 40
    • 0032171639 scopus 로고    scopus 로고
    • Association between secondary flow in models of the aortoceliac junction and subendothelial macrophages in the normal rabbit
    • Malinauskas RA, Sarraf P, Barber KM and Truskey GA: Association between secondary flow in models of the aortoceliac junction and subendothelial macrophages in the normal rabbit. Atherosclerosis 140: 121-134, 1998.
    • (1998) Atherosclerosis , vol.140 , pp. 121-134
    • Malinauskas, R.A.1    Sarraf, P.2    Barber, K.M.3    Truskey, G.A.4
  • 41
    • 0031006622 scopus 로고    scopus 로고
    • Measurement of flow rates through aortic branches in the rabbit in vivo
    • Barakat AI, Marini R and Colton CK: Measurement of flow rates through aortic branches in the rabbit in vivo. Lab Anim Sei 47: 184-189, 1997.
    • (1997) Lab Anim Sei , vol.47 , pp. 184-189
    • Barakat, A.I.1    Marini, R.2    Colton, C.K.3
  • 42
    • 0024405043 scopus 로고
    • Atherosclerosis and endothelium. II. Properties of aortic endothelial and smooth muscle cells cultured at various ambient pressures
    • Tokunga O, Fan JL and Watanabe T: Atherosclerosis and endothelium. II. Properties of aortic endothelial and smooth muscle cells cultured at various ambient pressures. Acta Pathol Jpn 39: 356-362, 1989.
    • (1989) Acta Pathol Jpn , vol.39 , pp. 356-362
    • Tokunga, O.1    Fan, J.L.2    Watanabe, T.3
  • 43
    • 0027955802 scopus 로고
    • Increased ambient pressure stimulates proliferation and morphologic changes in cultured endothelial cells
    • Sumpio BE, Windmann MD, Ricotta J, Awolesi MA and Watase M: Increased ambient pressure stimulates proliferation and morphologic changes in cultured endothelial cells. J Cell Physiol 158: 133-139, 1994.
    • (1994) J Cell Physiol , vol.158 , pp. 133-139
    • Sumpio, B.E.1    Windmann, M.D.2    Ricotta, J.3    Awolesi, M.A.4    Watase, M.5
  • 44
    • 0021177003 scopus 로고
    • Secondary flow and turbulence in a cone-plate device
    • Sdougos HP, Bussolari SR and Dewey CF Jr: Secondary flow and turbulence in a cone-plate device. J Fluid Mech 138: 379-404, 1984.
    • (1984) J Fluid Mech , vol.138 , pp. 379-404
    • Sdougos, H.P.1    Bussolari, S.R.2    Dewey, C.F.3
  • 46
    • 0029294440 scopus 로고
    • Characterization of a sudden expansion flow chamber to study the response of endothelium to flow recirculation
    • Truskey GA, Barber KM, Robey TC, Olivier LA and Combs MP: Characterization of a sudden expansion flow chamber to study the response of endothelium to flow recirculation. J Biomech Eng 117:203-210, 1995.
    • (1995) J Biomech Eng , vol.117 , pp. 203-210
    • Truskey, G.A.1    Barber, K.M.2    Robey, T.C.3    Olivier, L.A.4    Combs, M.P.5
  • 47
    • 0027333731 scopus 로고
    • Design and construction of a linear shear stress flow chamber
    • Usami S, Chien H-H, Zhao Y, Chien S and Skalak R: Design and construction of a linear shear stress flow chamber. Ann Biomed Eng 21: 77-83, 1993.
    • (1993) Ann Biomed Eng , vol.21 , pp. 77-83
    • Usami, S.1    Chien, H.-H.2    Zhao, Y.3    Chien, S.4    Skalak, R.5
  • 48
    • 0026911024 scopus 로고
    • The distribution of fluid forces on model arterial endothelium using computational fluid dynamics
    • Satcher RL, Bussolari SR, Gimbrone MA Jr and Dewey CF Jr: The distribution of fluid forces on model arterial endothelium using computational fluid dynamics. J Biomech Eng 114: 309-316, 1992.
    • (1992) J Biomech Eng , vol.114 , pp. 309-316
    • Satcher, R.L.1    Bussolari, S.R.2    Gimbrone, M.A.3    Dewey, C.F.4
  • 49
    • 0026284838 scopus 로고
    • A computational fluid mechanical study of flow over cultured endothelial cells
    • Sakurai A, Nakano A, Yamaguchi T, Masuda M and Fujiwara K: A computational fluid mechanical study of flow over cultured endothelial cells. Adv Bioeng 20: 299-302, 1991.
    • (1991) Adv Bioeng , vol.20 , pp. 299-302
    • Sakurai, A.1    Nakano, A.2    Yamaguchi, T.3    Masuda, M.4    Fujiwara, K.5
  • 50
    • 0000205063 scopus 로고
    • Shear stress distribution over confluently cultured endothelial cells studied by computational fluid mechanics
    • Yamaguchi T, Hoshiai K, Okino H, Kakurai A, Hanai S, Masuda M and Fujiwara K: Shear stress distribution over confluently cultured endothelial cells studied by computational fluid mechanics. Adv Bioeng 20: 167-170, 1993.
    • (1993) Adv Bioeng , vol.20 , pp. 167-170
    • Yamaguchi, T.1    Hoshiai, K.2    Okino, H.3    Kakurai, A.4    Hanai, S.5    Masuda, M.6    Fujiwara, K.7
  • 51
    • 0028157958 scopus 로고
    • Shear stress-induced reorganization of the surface topography of living endothelial cells imaged by atomic force microscopy
    • Barbee KA, Davies PF and Lai R: Shear stress-induced reorganization of the surface topography of living endothelial cells imaged by atomic force microscopy. Circ Res 74: 163-171, 1994.
    • (1994) Circ Res , vol.74 , pp. 163-171
    • Barbee, K.A.1    Davies, P.F.2    Lai, R.3
  • 52
    • 0028910024 scopus 로고
    • Subcellular distribution of shear stress at the surface of flow aligned and nonaligned endothelial monolayers
    • Barbee KA, Mundel T, Lal R and Davies PF: Subcellular distribution of shear stress at the surface of flow aligned and nonaligned endothelial monolayers. Am J Physiol 268: H1765-H1772, 1995.
    • (1995) Am J Physiol , vol.268 , pp. H1765-H1772
    • Barbee, K.A.1    Mundel, T.2    Lal, R.3    Davies, P.F.4
  • 53
    • 0019355002 scopus 로고
    • The dynamic response of vascular endothelial cells to fluid shear stress
    • Dewey CF Jr, Bussolari SR, Gimbrone MA Jr and Davies PF: The dynamic response of vascular endothelial cells to fluid shear stress. J Biomech Eng 103: 177-188, 1981.
    • (1981) J Biomech Eng , vol.103 , pp. 177-188
    • Dewey, C.F.1    Bussolari, S.R.2    Gimbrone, M.A.3    Davies, P.F.4
  • 54
    • 0019359912 scopus 로고
    • Vascular endothelial morphology as an indicator of the pattern of blood flow
    • Nerem RM, Levesque MJ and Cornhill JF: Vascular endothelial morphology as an indicator of the pattern of blood flow. J Biomech Eng 103: 172-177, 1981.
    • (1981) J Biomech Eng , vol.103 , pp. 172-177
    • Nerem, R.M.1    Levesque, M.J.2    Cornhill, J.F.3
  • 56
    • 0019432562 scopus 로고
    • Relationship between blood flow direction and endothelial cell orientation at arterial branch sites in rabbits and mice
    • Langille BL and Adamson SL: Relationship between blood flow direction and endothelial cell orientation at arterial branch sites in rabbits and mice. Circ Res 48: 481-488, 1981.
    • (1981) Circ Res , vol.48 , pp. 481-488
    • Langille, B.L.1    Adamson, S.L.2
  • 57
    • 0024379066 scopus 로고
    • In vivo modulation of endothelial F-actin microfilaments by experimental alterations in shear stress
    • Kim DW, Gotlieb AI and Langille BL: In vivo modulation of endothelial F-actin microfilaments by experimental alterations in shear stress. Arteriosclerosis 9: 439-445, 1989.
    • (1989) Arteriosclerosis , vol.9 , pp. 439-445
    • Kim, D.W.1    Gotlieb, A.I.2    Langille, B.L.3
  • 58
    • 0026911040 scopus 로고
    • Endothelial cell morphometry of atherosclerotic lesions and flow profiles at aortic bifurcations in cholesterol fed rabbits
    • Okano M and Yoshida Y: Endothelial cell morphometry of atherosclerotic lesions and flow profiles at aortic bifurcations in cholesterol fed rabbits. J Biomech Eng 114: 301-308, 1992.
    • (1992) J Biomech Eng , vol.114 , pp. 301-308
    • Okano, M.1    Yoshida, Y.2
  • 59
    • 0022366781 scopus 로고
    • Fibronectin and Factin redistribution in cultured endothelial cells exposed to shear stress
    • Wechezak AR, Viggers RF and Sauvage LR: Fibronectin and Factin redistribution in cultured endothelial cells exposed to shear stress. Lab Invest 53: 639-647, 1985.
    • (1985) Lab Invest , vol.53 , pp. 639-647
    • Wechezak, A.R.1    Viggers, R.F.2    Sauvage, L.R.3
  • 60
    • 0024597868 scopus 로고
    • Endothelial adherence under shear stress is dependent upon microfilament reorganization
    • Wechezak AR, Wight TN, Viggers RF and Sauvage LR: Endothelial adherence under shear stress is dependent upon microfilament reorganization. J Cell Physiol 139: 136-146, 1989.
    • (1989) J Cell Physiol , vol.139 , pp. 136-146
    • Wechezak, A.R.1    Wight, T.N.2    Viggers, R.F.3    Sauvage, L.R.4
  • 61
    • 0026954061 scopus 로고
    • Changes in the microstructure of cultured porcine aortic endothelial cells in the early stage after applying a fluid-imposed shear stress
    • Ookawa K, Sato M and Ohshima N: Changes in the microstructure of cultured porcine aortic endothelial cells in the early stage after applying a fluid-imposed shear stress. J Biomech 25: 1321-1328, 1992.
    • (1992) J Biomech , vol.25 , pp. 1321-1328
    • Ookawa, K.1    Sato, M.2    Ohshima, N.3
  • 62
    • 0028219509 scopus 로고
    • Quantitative studies of endothelial cell adhesion: Directional remodeling of focal adhesion sites in response to flow forces
    • Davies PF, Robotewskyj A and Griem ML: Quantitative studies of endothelial cell adhesion: directional remodeling of focal adhesion sites in response to flow forces. J Clin Invest 93: 2031-2038, 1994.
    • (1994) J Clin Invest , vol.93 , pp. 2031-2038
    • Davies, P.F.1    Robotewskyj, A.2    Griem, M.L.3
  • 63
    • 0023179166 scopus 로고
    • Micropipette aspiration of cultured bovine aortic endothelial cells exposed to shear stress
    • Sato M, Levesque MJ and Nerem RM: Micropipette aspiration of cultured bovine aortic endothelial cells exposed to shear stress. Arteriosclerosis 7: 276-286, 1987.
    • (1987) Arteriosclerosis , vol.7 , pp. 276-286
    • Sato, M.1    Levesque, M.J.2    Nerem, R.M.3
  • 64
    • 0030131099 scopus 로고    scopus 로고
    • Viscoelastic properties of cultured porcine aortic endothelial cells exposed to shear stress
    • Sato M, Ohshima N and Nerem RM: Viscoelastic properties of cultured porcine aortic endothelial cells exposed to shear stress. J Biomech 29: 461-467, 1996.
    • (1996) J Biomech , vol.29 , pp. 461-467
    • Sato, M.1    Ohshima, N.2    Nerem, R.M.3
  • 65
    • 0023188016 scopus 로고
    • Influence of a laminar steady state fluid imposed wall shear stress on the binding, internalization and degradation of LDL by cultured arterial endothelium
    • Sprague EA, Steinbach BL, Nerem RM and Schwartz CJ: Influence of a laminar steady state fluid imposed wall shear stress on the binding, internalization and degradation of LDL by cultured arterial endothelium. Circulation 76: 648-656, 1987.
    • (1987) Circulation , vol.76 , pp. 648-656
    • Sprague, E.A.1    Steinbach, B.L.2    Nerem, R.M.3    Schwartz, C.J.4
  • 67
    • 0027163936 scopus 로고
    • Regulation of endothelin 1 gene by fluid shear stress is transcriptionally mediated and independent of protein kinase C and cAMP
    • Malek AM, Greene AL and Izumo S: Regulation of endothelin 1 gene by fluid shear stress is transcriptionally mediated and independent of protein kinase C and cAMP. Proc Natl Acad Sei USA 90: 5999-6003, 1993.
    • (1993) Proc Natl Acad Sei USA , vol.90 , pp. 5999-6003
    • Malek, A.M.1    Greene, A.L.2    Izumo, S.3
  • 71
    • 0026504812 scopus 로고
    • Shear-induced platelet derived growth factor gene expression in human endothelial cells is mediated by protein kinase C
    • Hsieh HJ, Li NQ and Frangos JA: Shear-induced platelet derived growth factor gene expression in human endothelial cells is mediated by protein kinase C. J Cell Physiol 150: 552-558, 1992.
    • (1992) J Cell Physiol , vol.150 , pp. 552-558
    • Hsieh, H.J.1    Li, N.Q.2    Frangos, J.A.3
  • 72
    • 0027312906 scopus 로고
    • Fluid shear stress stimulates platelet-derived growth factor expression in endothelial cells
    • Mitsumata M, Fishel RS, Nerem RM, Alexander RW and Berk BC: Fluid shear stress stimulates platelet-derived growth factor expression in endothelial cells. Am J Physiol 265: H3-H8, 1993.
    • (1993) Am J Physiol , vol.265 , pp. H3-H8
    • Mitsumata, M.1    Fishel, R.S.2    Nerem, R.M.3    Alexander, R.W.4    Berk, B.C.5
  • 73
    • 0027231432 scopus 로고
    • Platelet-derived growth factor B chain promoter contains a cis-acting fluid shear-stress-responsive element
    • Resnick N, Collins T, Atkinson W, Bonthron DT, Dewey CF Jr and Gimbrone MA Jr: Platelet-derived growth factor B chain promoter contains a cis-acting fluid shear-stress-responsive element. Proc Natl Acad Sei USA 90: 4591-4595, 1993.
    • (1993) Proc Natl Acad Sei USA , vol.90 , pp. 4591-4595
    • Resnick, N.1    Collins, T.2    Atkinson, W.3    Bonthron, D.T.4    Dewey, C.F.5    Gimbrone, M.A.6
  • 74
    • 0027359453 scopus 로고
    • Fluid shear stress differentially modulates expression of genes encoding basic fibroblast growth factor and platelet-derived growth factor B chain in vascular endothelium
    • Malek AM, Gibbons GH, Dzau VJ and Izumo S: Fluid shear stress differentially modulates expression of genes encoding basic fibroblast growth factor and platelet-derived growth factor B chain in vascular endothelium. J Clin Invest 92: 2013-2021, 1993.
    • (1993) J Clin Invest , vol.92 , pp. 2013-2021
    • Malek, A.M.1    Gibbons, G.H.2    Dzau, V.J.3    Izumo, S.4
  • 75
    • 0028957211 scopus 로고
    • Fluid shear stress induces endothelial TGF-ßl transcription and production: Modulation by potassium channel blockade
    • Ohno M, Cooke JP, Dzau VJ and Gibbons GH: Fluid shear stress induces endothelial TGF-ßl transcription and production: modulation by potassium channel blockade. J Clin Invest 95: 1363-1369, 1995.
    • (1995) J Clin Invest , vol.95 , pp. 1363-1369
    • Ohno, M.1    Cooke, J.P.2    Dzau, V.J.3    Gibbons, G.H.4
  • 76
    • 0027931392 scopus 로고
    • Shear stress selectively upregulates ICAM-1 expression in cultured human vascular endothelial cells
    • Nagel T, Resnick N, Atkinson WJ, Dewey CF Jr and Gimbrone MA Jr: Shear stress selectively upregulates ICAM-1 expression in cultured human vascular endothelial cells. J Clin Invest 94: 885-891, 1994.
    • (1994) J Clin Invest , vol.94 , pp. 885-891
    • Nagel, T.1    Resnick, N.2    Atkinson, W.J.3    Dewey, C.F.4    Gimbrone, M.A.5
  • 77
    • 0029022552 scopus 로고
    • Shear stress-mediated changes in the expression of leukocyte adhesion receptors on human umbilical vein endothelial cells in vitro
    • Sampath R, Kukielka GL, Smith CW, Eskin SG and Mclntire LV: Shear stress-mediated changes in the expression of leukocyte adhesion receptors on human umbilical vein endothelial cells in vitro. Ann Biomed Eng 23: 247-256, 1995.
    • (1995) Ann Biomed Eng , vol.23 , pp. 247-256
    • Sampath, R.1    Kukielka, G.L.2    Smith, C.W.3    Eskin, S.G.4    McLntire, L.V.5
  • 79
    • 0027505606 scopus 로고
    • Pulsatile and steady flow induces c-fos expression in human endothelial cells
    • Hsieh HJ, Li NQ and Frangos JA: Pulsatile and steady flow induces c-fos expression in human endothelial cells. J Cell Physiol 154: 143-151, 1993.
    • (1993) J Cell Physiol , vol.154 , pp. 143-151
    • Hsieh, H.J.1    Li, N.Q.2    Frangos, J.A.3
  • 80
    • 0027376140 scopus 로고
    • Fluid shear stress induces synthesis and nuclear localization of c-fos in cultured human endothelial cells
    • Ranjan V and Diamond SL: Fluid shear stress induces synthesis and nuclear localization of c-fos in cultured human endothelial cells. Biochem Biophys Res Commun 196: 79-84, 1993.
    • (1993) Biochem Biophys Res Commun , vol.196 , pp. 79-84
    • Ranjan, V.1    Diamond, S.L.2
  • 81
    • 0024285834 scopus 로고
    • Hemodynamic shear stress activates a K+ current in vascular endothelial cells
    • Olesen SP, Clapham DE and Davies PF: Hemodynamic shear stress activates a K+ current in vascular endothelial cells. Nature 331: 168-170, 1988.
    • (1988) Nature , vol.331 , pp. 168-170
    • Olesen, S.P.1    Clapham, D.E.2    Davies, P.F.3
  • 82
    • 0024121617 scopus 로고
    • Hydrodynamic hyperpolarization of endothelial cells
    • Nakache M and Gaub HE: Hydrodynamic hyperpolarization of endothelial cells. Proc Natl Acad Sei USA 85: 1841-1842, 1988.
    • (1988) Proc Natl Acad Sei USA , vol.85 , pp. 1841-1842
    • Nakache, M.1    Gaub, H.E.2
  • 83
    • 0028840911 scopus 로고
    • Shear activated channels in cell-attached patches of cultured bovine aortic endothelial cells
    • Jacobs ER, Cheliakine C, Gebremedhin D, Davies PF and Harder DR: Shear activated channels in cell-attached patches of cultured bovine aortic endothelial cells. Pflugers Arch 431: 129-131, 1995.
    • (1995) Pflugers Arch , vol.431 , pp. 129-131
    • Jacobs, E.R.1    Cheliakine, C.2    Gebremedhin, D.3    Davies, P.F.4    Harder, D.R.5
  • 84
    • 84943408326 scopus 로고    scopus 로고
    • A flowactivated chloride-selective current in vascular endothelial cells
    • (In press)
    • Barakat AI, Leaver EV, Pappone PA and Davies PF: A flowactivated chloride-selective current in vascular endothelial cells. Circ Res (In press).
    • Circ Res
    • Barakat, A.I.1    Leaver, E.V.2    Pappone, P.A.3    Davies, P.F.4
  • 85
    • 0029822797 scopus 로고    scopus 로고
    • Fluid flow rapidly activates G proteins in human endothelial cells. Involvement of G proteins in mechanochemical signal transduction
    • Gudi SRP, Clark CB and Frangos JA: Fluid flow rapidly activates G proteins in human endothelial cells. Involvement of G proteins in mechanochemical signal transduction. Circ Res 79: 834-839, 1996.
    • (1996) Circ Res , vol.79 , pp. 834-839
    • Gudi, S.R.P.1    Clark, C.B.2    Frangos, J.A.3
  • 86
    • 0032478310 scopus 로고    scopus 로고
    • Modulation of GTPase activity of G proteins by fluid shear stress and phospholipid composition
    • Gudi S, Nolan JP and Frangos JA: Modulation of GTPase activity of G proteins by fluid shear stress and phospholipid composition. Proc Natl Acad Sei USA 95: 2515-2519, 1998.
    • (1998) Proc Natl Acad Sei USA , vol.95 , pp. 2515-2519
    • Gudi, S.1    Nolan, J.P.2    Frangos, J.A.3
  • 87
    • 0026546623 scopus 로고
    • Fluid shear stress modulates cytosolic free calcium in vascular endothelial cells
    • Shen J, Luscinskas FW, Connolly A, Dewey CF Jr and Gimbrone MA Jr: Fluid shear stress modulates cytosolic free calcium in vascular endothelial cells. Am J Physiol 262: C384-C390, 1992.
    • (1992) Am J Physiol , vol.262 , pp. C384-C390
    • Shen, J.1    Luscinskas, F.W.2    Connolly, A.3    Dewey, C.F.4    Gimbrone, M.A.5
  • 88
    • 0026695285 scopus 로고
    • Flowinduced calcium transients in single endothelial cells: Spatial and temporal analysis
    • Geiger RV, Berk BC, Alexander RW and Nerem RM: Flowinduced calcium transients in single endothelial cells: spatial and temporal analysis. Am J Physiol 262: C1411-C1417, 1992.
    • (1992) Am J Physiol , vol.262 , pp. C1411-C1417
    • Geiger, R.V.1    Berk, B.C.2    Alexander, R.W.3    Nerem, R.M.4
  • 89
    • 0025744835 scopus 로고
    • Flow modulation of agonist (ATP)- response (Ca2+) coupling in vascular endothelial cells
    • Dull RO and Davies PF: Flow modulation of agonist (ATP)- response (Ca2+) coupling in vascular endothelial cells. Am J Physiol 261: H149-H156, 1991.
    • (1991) Am J Physiol , vol.261 , pp. H149-H156
    • Dull, R.O.1    Davies, P.F.2
  • 90
    • 0023760164 scopus 로고
    • Cytoplasmic calcium responses to fluid shear stress in cultured vascular endothelial cells
    • Ando J, Komatsude T and Kamiya A: Cytoplasmic calcium responses to fluid shear stress in cultured vascular endothelial cells. In Vitro Cell Dev Biol 24: 871-877, 1988.
    • (1988) Vitro Cell Dev Biol , vol.24 , pp. 871-877
    • Ando, J.1    Komatsude, T.2    Kamiya, A.3
  • 91
    • 84943409468 scopus 로고    scopus 로고
    • Cytoskeletal dynamics in living endothelial cells exposed to steady laminar shear stress
    • Helmke BP, Goldman RD and Davies PF: Cytoskeletal dynamics in living endothelial cells exposed to steady laminar shear stress. FASEB J 13: A1019, 1999.
    • (1999) FASEB J , vol.13 , pp. A1019
    • Helmke, B.P.1    Goldman, R.D.2    Davies, P.F.3
  • 92
    • 84943385619 scopus 로고    scopus 로고
    • Intermediate filament dynamics in bovine aortic endothelial cells are altered by shear stress
    • Seetharam A, Helmke BP, Goldman RD and Davies PF: Intermediate filament dynamics in bovine aortic endothelial cells are altered by shear stress. FASEB J 13: A855, 1999.
    • (1999) FASEB J , vol.13 , pp. A855
    • Seetharam, A.1    Helmke, B.P.2    Goldman, R.D.3    Davies, P.F.4
  • 93
    • 0028291843 scopus 로고
    • Stimulation of transcription factors NFtcB and API in endothelial cells subjected to shear stress
    • Lan Q, Mercurius KO and Davies PF: Stimulation of transcription factors NFtcB and API in endothelial cells subjected to shear stress. Biochem Biophys Res Commun 201: 950-956, 1994.
    • (1994) Biochem Biophys Res Commun , vol.201 , pp. 950-956
    • Lan, Q.1    Mercurius, K.O.2    Davies, P.F.3
  • 94
    • 0025724919 scopus 로고
    • Flow activates an endothelial potassium channel to release an endogenous nitrovasodilator
    • Cooke JP, Rossitch E, Andon NA, Loscalzo J and Dzau V: Flow activates an endothelial potassium channel to release an endogenous nitrovasodilator. J Clin Invest 88: 1663-1671, 1991.
    • (1991) J Clin Invest , vol.88 , pp. 1663-1671
    • Cooke, J.P.1    Rossitch, E.2    Andon, N.A.3    Loscalzo, J.4    Dzau, V.5
  • 95
    • 0027267272 scopus 로고
    • Shear stress elevates endothelial cGMP: Role of a potassium channel and G protein coupling
    • Ohno M, Gibbons GH, Dzau V and Cooke JP: Shear stress elevates endothelial cGMP: role of a potassium channel and G protein coupling. Circulation 88: 193-197, 1993.
    • (1993) Circulation , vol.88 , pp. 193-197
    • Ohno, M.1    Gibbons, G.H.2    Dzau, V.3    Cooke, J.P.4
  • 96
    • 84943369058 scopus 로고    scopus 로고
    • Laminar shear stress-induced Na-K-Cl cotransport expression: Dependence on K+ and CI" channels
    • O'Donnell ME, Suvatne J and Barakat AI: Laminar shear stress-induced Na-K-Cl cotransport expression: dependence on K+ and CI" channels. FASEB J 13: A857, 1999.
    • (1999) FASEB J , vol.13 , pp. A857
    • O'Donnell, M.E.1    Suvatne, J.2    Barakat, A.I.3
  • 97
    • 0028891155 scopus 로고
    • Cytoskeleton modulates gating of voltage-dependent sodium channel in heart
    • Undrovinas AI, Shander GS and Makielski JC: Cytoskeleton modulates gating of voltage-dependent sodium channel in heart. Am J Physiol 269: H203-H214, 1995.
    • (1995) Am J Physiol , vol.269 , pp. H203-H214
    • Undrovinas, A.I.1    Shander, G.S.2    Makielski, J.C.3
  • 98
    • 0029102078 scopus 로고
    • Role of the actin cytoskeleton on epithelial Na+ channel regulation
    • Cantillo HF: Role of the actin cytoskeleton on epithelial Na+ channel regulation. Kidney Int48: 970-984, 1995.
    • (1995) Kidney Int , vol.48 , pp. 970-984
    • Cantillo, H.F.1
  • 99
    • 0028986463 scopus 로고
    • Actin-dependent activation of the ion conductances in bronchial epithelial cells
    • Hug T, Koslowsky T, Ecke D, Greger R and Kunzelmann K: Actin-dependent activation of the ion conductances in bronchial epithelial cells. Pflugers Arch 429: 682-690, 1995.
    • (1995) Pflugers Arch , vol.429 , pp. 682-690
    • Hug, T.1    Koslowsky, T.2    Ecke, D.3    Greger, R.4    Kunzelmann, K.5
  • 100
    • 0028170820 scopus 로고
    • Small GTP-binding proteins and the regulation of the actin cytoskeleton
    • Hall A: Small GTP-binding proteins and the regulation of the actin cytoskeleton. Annu Rev Cell Biol 10: 31-54, 1994.
    • (1994) Annu Rev Cell Biol , vol.10 , pp. 31-54
    • Hall, A.1
  • 101
    • 0024986794 scopus 로고
    • Specific associations between tubulin and G proteins: Participation of cytoskeletal elements in cellular signal transduction
    • Rasenick MM, Wang N and Yan K: Specific associations between tubulin and G proteins: participation of cytoskeletal elements in cellular signal transduction. Adv Second Messenger Phosphoprotein Res 24: 381-386, 1990.
    • (1990) Adv Second Messenger Phosphoprotein Res , vol.24 , pp. 381-386
    • Rasenick, M.M.1    Wang, N.2    Yan, K.3
  • 102
    • 0027172919 scopus 로고
    • Mechanotransduction across the cell surface and through the cytoskeleton
    • Wang N, Butler JP and Ingber DE: Mechanotransduction across the cell surface and through the cytoskeleton. Science 260: 1124-1127, 1993.
    • (1993) Science , vol.260 , pp. 1124-1127
    • Wang, N.1    Butler, J.P.2    Ingber, D.E.3
  • 103
    • 0030006215 scopus 로고    scopus 로고
    • Mechanisms of endothelial cell shape change and cytoskeletal remodeling in response to fluid shear stress
    • Malek AM and Izumo S: Mechanisms of endothelial cell shape change and cytoskeletal remodeling in response to fluid shear stress. J Cell Sei 109: 713-726, 1996.
    • (1996) J Cell Sei , vol.109 , pp. 713-726
    • Malek, A.M.1    Izumo, S.2
  • 105
    • 0242347624 scopus 로고    scopus 로고
    • Dynamic properties of intermediate filaments in cultured endothelial cells; Effects of controlled fluid shear stress
    • Moncada S, Stamler J, Gross S and Higgs EA (eds). Portland, London p251
    • Flitney FW, Goldman RD, Skalli O, Mercurius K and Davies PF: Dynamic properties of intermediate filaments in cultured endothelial cells; effects of controlled fluid shear stress. In: The Biology of Nitric Oxide. Moncada S, Stamler J, Gross S and Higgs EA (eds). Portland, London p251, 1996.
    • (1996) The Biology of Nitric Oxide
    • Flitney, F.W.1    Goldman, R.D.2    Skalli, O.3    Mercurius, K.4    Davies, P.F.5
  • 106
    • 0031008850 scopus 로고    scopus 로고
    • Expression of the bumetanide-sensitive Na- K-Cl cotransporter BSC2 is differentially regulated by fluid mechanical and inflammatory cytokine stimuli in vascular endothelium
    • Topper JN, Wasserman SM, Anderson KR, Cai J, Falb D and Gimbrone MA Jr: Expression of the bumetanide-sensitive Na- K-Cl cotransporter BSC2 is differentially regulated by fluid mechanical and inflammatory cytokine stimuli in vascular endothelium. J Clin Invest 99: 2941-2949, 1997.
    • (1997) J Clin Invest , vol.99 , pp. 2941-2949
    • Topper, J.N.1    Wasserman, S.M.2    Anderson, K.R.3    Cai, J.4    Falb, D.5    Gimbrone, M.A.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.