Human immunodeficiency virus-1 (HIV-1)-Tat protein promotes migration of acquired immunodeficiency syndrome-related lymphoma cells and enhances their adhesion to endothelial cells

Blood

Volumn 94, Issue 5, 1999, Pages 1747-1754

  Chirivi, Renato G S ^b   Taraboletti, Giulia ^b   Bani, Maria Rosa ^b   Barra, Luca ^b   Piccinini, Giampiero ^b   Giacca, Mauro ^b   Bussolino, Federico ^b   Giavazzi, Raffaella ^a  

^a MARIO NEGRI INST PHARMACOL RES   (Italy)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

ARGINYLGLYCYLASPARTIC ACID; BETA1 INTEGRIN; ENDOTHELIAL LEUKOCYTE ADHESION MOLECULE 1; INTEGRIN; INTERCELLULAR ADHESION MOLECULE 1; SCLEROPROTEIN; TRANSACTIVATOR PROTEIN; VASCULAR CELL ADHESION MOLECULE 1;

AIDS RELATED COMPLEX; ANTIGEN EXPRESSION; ARTICLE; BURKITT LYMPHOMA; CELL ADHESION; CELL MIGRATION; CELL SURFACE; CONTROLLED STUDY; ENDOTHELIUM CELL; FLOW CYTOMETRY; GENE MUTATION; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; LYMPHOMA CELL; NONHODGKIN LYMPHOMA; PRIORITY JOURNAL; VASCULAR ENDOTHELIUM;

EID: 0033200027     PISSN: 00064971     EISSN: None     Source Type: Journal    
DOI: 10.1182/blood.v94.5.1747.417a02_1747_1754     Document Type: Article

References (56)

1. Levine AM: Acquired immunodeficiency syndrome-related lymphoma. Blood 80:8, 1992
2. Karp JE, Broder S: Acquired immunodeficiency syndrome and non-Hodgkin's lymphomas. Cancer Res 51:4743, 1991
3. Beral V, Peterman T, Berkelman R, Jaffe H: AIDS-associated non-Hodgkin lymphoma. Lancet 337:805, 1991
4. Knowles DM, Inghirami G, Ubriaco A, Dalla-Favera R: Molecular genetic analysis of three AIDS-associated neoplasms of uncertain lineage demonstrates their B-cell derivation and the possible pathogenetic role of the Epstein-Barr virus. Blood 73:792, 1989
5. Gaidano G, Carbone A, Dalla-Favera R: Pathogenesis of AIDS-related lymphomas: Molecular and histogenetic heterogeneity. Am J Pathol 152:623, 1998
6. Ballerini P, Gaidano G, Gong JZ, Tassi V, Saglio G, Knowles DM, Dalla-Favera R: Multiple genetic lesions in acquired immunodeficiency syndrome-related non-Hodgkin's lymphoma. Blood 81:166, 1993
7. Gaidano G, Lo Coco F, Ye BH, Shibata D, Levine AM, Knowles DM, Dalla-Favera R: Rearrangements of the BCL-6 gene in acquired immunodeficiency syndrome-associated non-Hodgkin's lymphoma: Association with diffuse large-cell subtype. Blood 84:397, 1994
8. Cesarman E, Chang Y, Moore PS, Said JW, Knowles DM: Kaposi's sarcoma-associated herpesvirus-like DNA sequences in AIDS-related body-cavity-based lymphomas. N Engl J Med 332:1186, 1995
9. Gaidano G, Carbone A, Pastore C, Capello D, Migliazza A, Gloghini A, Roncella S, Ferrarini M, Saglio G, Dalla-Favera R: Frequent mutation of the 5′ noncoding region of the BCL-6 gene in acquired immunodeficiency syndrome-related non-Hodgkin's lymphomas. Blood 89:3755, 1997
10. Moses AV, Stenglein SG, Strussenberg JG, Wehrly K, Chesebro B, Nelson JA: Sequences regulating tropism of human immunodeficiency virus type 1 for brain capillary endothelial cells map to a unique region on the viral genome. J Virol 70:3401, 1996
11. Moses AV, Bloom FE, Pauza CD, Nelson JA: Human immunodeficiency virus infection of human brain capillary endothelial cells occurs via a CD4/galactosylceramide-independent mechanism. Proc Natl Acad Sci USA 90:10474, 1993
12. Moses AV, Williams SE, Strussenberg JG, Heneveld ML, Ruhl RA, Bakke AC, Bagby GC, Nelson JA: HIV-1 induction of CD40 on endothelial cells promotes the outgrowth of AIDS-associated B-cell lymphomas. Nat Med 3:1242, 1997
13. Dhawan S, Puri RK, Kumar A, Duplan H, Masson J-M, Aggarwal BB: Human immunodeficiency virus-1-Tat protein induces the cell surface expression of endothelial leukocyte adhesion molecule-1, vascular cell adhesion molecule-1, and intercellular adhesion molecule-1 in human endothelial cells. Blood 90:1535, 1997
14. Freedman AS, Munro JM, Rice GE, Bevilacqua MP, Morimoto C, McIntyre BW, Rhynhart K, Pober JS, Nadler LM: Adhesion of human B cells to germinal centers in vitro involves VLA-4 and INCAM-110. Science 249:1030, 1990
15. Vaishnav YN, Wong-Staal F: The biochemistry of AIDS. Annu Rev Biochem 60:577, 1991
16. Westendorp MO, Shatrov VA, Schulze-Osthoff K, Frank R, Kraft M, Los M, Krammer PH, Droge W, Lehmann V: HIV-1 Tat potentiates TNF-induced NF-κB activation and cytotoxicity by altering the cellular redox state. EMBO J 14:546, 1995
17. Siekevitz M, Feinberg MB, Holbrook N, Wong-Staal F, Greene WC: Activation of interleukin 2 and interleukin 2 receptor (Tac) promoter expression by the trans-activator (tat) gene product of human T-cell leukemia virus, type 1. Proc Natl Acad Sci USA 84:5389, 1987
18. Scala G, Ruocco MR, Ambrosino C, Mallardo M, Giordano V, Baldassarre F, Dragonetti E, Quinto I, Venuta S: The expression of the interleukin 6 gene is induced by the human immunodeficiency virus I TAT protein. J Exp Med 179:961, 1994
19. Howcroft TK, Strebel K, Martin MA, Singer DS: Repression of MHC class I gene promoter activity by two-exon Tat of HIV. Science 260:1320, 1993
20. Gibellini D, Caputo A, Capitani S, La Placa M, Zauli G: Upregulation of c-Fos in activated T lymphoid and monocytic cells by human immunodeficiency virus-1 Tat protein. Blood 89:1654, 1997
21. Buonaguro L, Buonaguro FM, Giraldo G, Ensoli B: The human immunodeficiency virus type 1 Tat protein transactivates tumor necrosis factor beta gene expression through a TAR-like structure. J Virol 68:2677, 1994
22. Li CJ, Wang C, Friedman DJ, Pardee AB: Reciprocal modulations between p53 and Tat of human immunodeficiency virus type 1. Proc Natl Acad Sci USA 92:5461, 1995
23. Ensoli B, Buonaguro L, Barillari G, Fiorelli V, Gendelman R, Morgan RA, Wingfield P, Gallo RC: Release, uptake, and effects of extracellular human immunodeficiency virus type 1 Tat protein on cell growth and viral transactivation. J Virol 67:277, 1993
24. Chang HC, Samaniengo F, Nair BC, Buonaguro L, Ensoli B: HIV-1 Tat protein exits from cells via a leaderless secretory pathway and binds to extracellular matrix-associated heparan sulphate proteoglycans through its basic region. AIDS 11:1421, 1997
25. Zauli G, Gibellini D, Celeghini C, Mischiati C, Bassini A, La Placa M, Capitani S: Pleiotropic effects of immobilized versus soluble recombinant HIV-1 Tat protein on CD3-mediated activation, induction of apoptosis, and HIV-1 long terminal repeat transactivation in purified CD4+ T lymphocytes. J Immunol 157:2216, 1996
26. Westendorp MO, Frank R, Ochsenbauer C, Stricker K, Dhein J, Walczak H, Debatin K-M, Krammer PH: Sensitization of T cells to CD95-mediated apoptosis by HIV-1 Tat and gp120. Nature 375:497, 1995
27. Mitola S, Sozzani S, Luini W, Primo L, Borstatti A, Weich H, Bussolino F: Tat-human immunodeficiency virus-1 induces human monocyte chemotaxis by activation of vascular endothelial growth factor receptor-1. Blood 90:1365, 1997
28. Lotz M, Clark-Lewis I, Ganu V: HIV-1 transactivator protein Tat induces proliferation and TGFβ expression in human articular chondrocytes. J Cell Bioll 24:365, 1994
29. Lafrenie RM, Wahl LM, Epstein JS, Hewlett IK, Yamada KM, Dhawan S: HIV-1-Tat protein promotes chemotaxis and invasive behavior by monocytes. J Immunol 157:974, 1996
30. Ensoli B, Gendelman R, Markham P, Fiorelli V, Colombini S, Raffeld M, Cafaro A, Chang H-K, Brady JN, Gallo RC: Synergy between basic fibroblast growth factor and HIV-1 Tat protein in induction of Kaposi's sarcoma. Nature 371:674, 1994
31. Albini A, Soldi R, Giunciuglio D, Giraudo E, Benelli R, Primo L, Noonan D, Salio M, Camussi G, Rockl W, Bussolino F: The angiogenesis induced by HIV-1 tat protein is mediated by the Flk-1/KDR receptor on vascular endothelial cells. Nat Med 2:1371, 1996
32. Huang L, Li CJ, Pardee AB: Human immunodeficiency virus type 1 TAT protein activates B lymphocytes. Biochem Biophys Res Commun 237:461, 1997
33. Ensoli B, Barillari G, Salahuddin SZ, Gallo RC, Wong-Staal F: Tat protein of HIV-1 stimulates growth of cells derived from Kaposi's sarcoma lesions of AIDS patients. Nature 345:84, 1990
34. Hofman FM, Wright AD, Dohadwala MM, Wong-Staal F, Walker SM: Exogenous tat protein activates human endothelial cells. Blood 82:2774, 1993
35. Barillari G, Gendelman R, Gallo RC, Ensoli B: The Tat protein of human immunodeficiency virus type 1, a growth factor for AIDS Kaposi sarcoma and cytokine-activated vascular cells, induces adhesion of the same cell types by using integrin receptors recognizing the RGD amino acid sequence. Proc Natl Acad Sci USA 90:7941, 1993
36. Albini A, Barillari G, Benelli R, Gallo RC, Ensolo B: Angiogenic properties of human immunodeficiency virus type 1 Tat protein. Proc Natl Acad Sci USA 92:4838, 1995
37. Kiwanuka J, Shiramizu B, Sandlund T, Barriga F, McManaway M, Novikovs L, Huber B, Magrath IT: The contribution of Burkitt's lymphoma cell lines to the understanding of the pathogenesis of Burkitt's lymphoma. Cancer Rev 10:63, 1988
38. Jaffe E, Nachman R, Becker C, Minick C: Culture of human endothelial cells derived from umbilical veins; Identification of morphologic and immunologic criteria. J Clin Invest 52:2745, 1973
39. Whright CM, Selber BK, Paskalis H, Pavlakis GN: Expression and characterization of the trans activator of HTLV-III/LAV virus. Science 234:988, 1986
40. Kingston RE, Moore DD: Isotopic assay for reporter gene activity, in Ausubel MF, Brent R, Kingston RE, Moore DD, Seidman JG, Smith JA, Struhl K (eds): Current Protocols in Molecular Biology. New York, NY, Wiley, 1995, p 9.7.A
41. Albini A, Fontanini G, Masiello L, Tacchetti C, Bigini D, Luzzi P, Noonan DM, Stetler-Sevenson WG: Angiogenic potential in vivo by Kaposi's sarcoma cell-free supernatants and HIV-1 tat product: Inhibition of KS-like lesions by tissue inhibitor of metalloproteinase-2. AIDS 8:1237, 1994
42. Marzio G, Tyagi M, Gutierrez MI, Giacca M: HIV-1 tat transactivator recruits p300 and CREB-binding protein histone acetyltransferases to the viral promoter. Proc Natl Acad Sci USA 95:13519, 1998
43. Taraboletti G, Roberts D, Liotta LA, Giavazzi R: Platelet thrombospondin modulates endothelial cell adhesion, motility, and growth: A potential angiogenesis regulatory factor. J Cell Biol 111:765, 1990
44. Chirivi RGS, Garofalo A, Martin-Padura I, Mantovani A, Giavazzi R: Interleukin-1 receptor antagonist inhibits the augmentation of metastasis induced by interleukin-1 or lipopolysaccharide in a human melanoma/nude mouse model. Cancer Res 53:5051, 1993
45. Dejana E, Bertocchi F, Bortolami MC, Regonesi A, Tonta A, Breviario F, Giavazzi R: Interleukin 1 promotes tumor cell adhesion to cultured human endothelial cells. J Clin Invest 82:1466, 1988
46. McGrath MS, Shiramizu B, Meeker TC, Kaplan LD, Herndier B: AIDS-associated polyclonal lymphoma: Identification of a new HIV-associated process. J Acquir Immune Defic Syndr 4:408, 1991
47. Albini A, Benelli R, Presta M, Rusnati M, Ziche M, Rubartelli A, Paglialunga G, Bussolino F, Noonan D: HIV-tat protein is a heparin-binding angiogenic growth factor, Oncogene 12:289, 1996
48. Albini A, Benelli R, Giunciuglio D, Cai T, Mariani G, Ferrini S, Noonan DM: Identification of a novel domain of HIV tat involved in monocyte chemotaxis. J Biol Chem 273:15895, 1998
49. Vogel BE, Lee S-J, Hildebrand A, Craig W, Pierschbacher MD, Wong-Staal F, Ruoslahti E: A novel integrin specificity exemplified by binding of the αvβ5 integrin to the basic domain of the HIV Tat protein and vitronectin. J Cell Biol 121:461, 1993
50. Fiedler W, Graeven U, Ergun S, Verago S, Kilic N, Stockschlader M, Hossfeld DK: Vascular endothelial growth factor, a possible paracrine growth factor in human acute myeloid leukemia. Blood 89:1870, 1997
51. Soker S, Takashima S, Miao HQ, Neufeld G, Klagsbrun M: Neuropilin-1 is expressed by endothelial and tumor cells as an isoform-specific receptor for vascular endothelial growth factor. Cell 92:735, 1998
52. Prieto J, Beatty PG, Clark EA, Patarroyo M: Molecules mediating adhesion of T and B cells, monocytes and granulocytes to vascular endothelial cells. Immunology 63:631, 1988
53. Flores-Romo L, Estoppey D, Bacon KB: Anti-CD40 antibody stimulates the VLA-4-dependent adhesion of normal and LFA-1-deficient B cells to endothelium. Immunology 79:445, 1993
54. Carlos TM, Schwartz BR, Kovach NL, Yee E, Rosso M, Osborn L, Chi-Rosso G, Newman B, Lobb R, Harlan JM: Vascular cell adhesion molecule-1 mediates lymphocyte adherence to cytokine-activated cultured human endothelial cells. Blood 76:965, 1990
55. Rice GE, Munro JM, Bevilacqua MP: Inducible cell adhesion molecule 110 (INCAM-110) is an endothelial receptor for lymphocytes. A CD11/CD18-independent adhesion mechanism. J Exp Med 171: 1369, 1990
56. Patarroyo M, Prieto J, Ernberg I, Gahmberg CG: Absence, or low expression, of leukocyte adhesion molecule CD11 and CD18 on Burkitt lymphoma cells. Int J Cancer 41:901, 1988