Tat-human immunodeficiency virus-1 induces human monocyte chemotaxis by activation of vascular endothelial growth factor receptor-1

Blood

Volumn 90, Issue 4, 1997, Pages 1365-1372

  Mitola, Stefania ^b   Sozzani, Silvano ^b   Luini, Walter ^b   Primo, Luca ^b   Borsatti, Alessandro ^b   Weich, Herbert ^b   Bussolino, Federico ^a  

^a Biologia e Chimica Medico   (Italy)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

ANTIGEN P24; CD14 ANTIGEN; CD3 ANTIGEN; CHEMOKINE RECEPTOR; EOTAXIN; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; MACROPHAGE INFLAMMATORY PROTEIN 1ALPHA; MACROPHAGE INFLAMMATORY PROTEIN 1BETA; MESSENGER RNA; MONOCYTE CHEMOTACTIC PROTEIN 1; MONOCYTE CHEMOTACTIC PROTEIN 4; RANTES;

ARTICLE; CELL SURFACE; CONTROLLED STUDY; DENDRITIC CELL; FLUORESCENCE ACTIVATED CELL SORTER; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; LANGERHANS CELL; MACROPHAGE; MONONUCLEAR CELL; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; T LYMPHOCYTE; VIRUS CELL INTERACTION;

EID: 0030769372     PISSN: 00064971     EISSN: None     Source Type: Journal    
DOI: 10.1182/blood.v90.4.1365     Document Type: Article

References (50)

1. Griffin GE, Leung K, Folks MT, Kunkel S, Nabel GJ: Activation of HIV gene expression during monocyte differentiation by induction of NF-kB. Nature 339:70, 1989
2. Pantaleo G, Graziosi C, Demarest Butini L, Montroni M, Fox CH, Orenstein JM, Kotler DP, Fauci AS: HIV infection is active and progressive in lymphoid tissue during the clinically latent stage of disease. Nature 362:355, 1993
3. Poli G, Bressler P, Kinter A. Duh E, Timmer WC, Rabson A, Justement JS, Stanley S, Fauci AS: Interleukin 6 induces HIV expression in infected monocytic cells alone and in synergy with TNF( by trascriptional and post-trascriptional mechanisms. J Exp Med 172:151, 1990
4. Koyanagi Y, O'Brien WA, Zhao JQ, Golde DW, Gasson JC, Chen ISY: Cytokines alter production of HIV-1 from primary mononuclear phagocytes. Science 241:1673, 1988
5. Pomerantz RJ, Feinberg MB, Trono D, Baltimore D: Lipopolysaccharide is a potent monocyte/macrophage-specific stimulator of human HIV-1 expression. J Exp Med 172:253, 1990
6. Gilles PN. Lathey JL, Spector SA: Replication of macrophagetropic and T-cell-tropic strains of human immunodeficiency virus type 1 is augmented by macrophage-endothelial cell contact. J Virol 69:2133, 1995
7. Dhawan S, Weeks BS, Soderland C, Schnaper HW, Toro LA, Asthana SP, Hewlett IK, Stetler-Stevenson WG, Yamada SS, Yamada KM, Meltzer MS: HIV-1 infection alters monocyte interactions with human microvascular endothelial cells. J Immunol 154:422, 1995
8. Genis P, Marti J, Berton EW, Boyle T, Gelbard HA, Dzenko K, Keane RW, Resnick L, Mizrachi Y, Volsky DJ, Epstein LG, Gendelman HE: Cytokines and arachidonic metabolites produced during human immunodeficiency virus (HlV)-infected macrophageastroglia interactions: Implications for the neuropathogenesis of HIV disease. J Exp Med 176:1703, 1992
9. Le Naour R, Raoul H, Mabondzo H, Ripoll L, Bartholeyns J, Romet-Lemon JL, Dormont J: Functional consequences of monocyte/macrophage infection by HIV1. Res Immunol 143:49, 1992
10. Vaishnaw YN, Wong-Staal F: The biochemistry of AIDS. Annu Rev Biochem 60:577, 1991
11. Gibellini D, Zauli G, Re MC, Milani D, Furlini G, Caramelli E, Capitani S, La Placa M: Recombinant human immunodeficiency virus type-1 (HIV-1) Tat protein sequentially up-regulates IL-6 and TGF-β1 mRNA expression and protein synthesis in peripheral blood monocytes. Br J Haematol 88:261, 1994
12. Scala G, Ruocco MR, Ambrosino C, Mallardo M, Giordano V, Baldassarre F, Dragonetti E, Quinto I, Venuta S: The expression of the interleukin 6 gene is induced by the human Immunodeficiency virus 1 Tat protein. J Exp Med 179:961, 1994
13. Westendorp MO, Shatrov VA, Schulze-Osthoff K, Frank R, Kraft M, Los M, Krammer PH, Droge W, Lehmann V: HIV-1 Tat potentiates TNF-induced NF-kappa B activation and cytotoxicity by altering the cellular redox state. EMBO J 14:546, 1995
14. Siekevitz M, Feinberg MB, Holbrook N, Wong-Staal F, Greene WC: Activation of interleukin 2 and interleukin 2 receptor (Tac) promoter expression by the trans-activator (tat) gene product of human T-cell leukemia virus, type 1. Proc Natl Acad Sci USA 84:5389, 1987
15. Buonaguro L, Buonaguro FM, Giraldo G, Ensoli B: The human immunodeficiency virus type 1 Tat protein transactivates tumor necrosis factor beta gene expression through a TAR-like structure. J Virol 68:2677, 1994
16. Li CJ, Wang C, Friedman DJ, Pardee AB: Reciprocal modulations between p53 and Tat of human immunodeficiency virus type 1. Proc Natl Acad Sci USA 92:5461, 1995
17. Howcroft TK, Strebel K, Martin MA, Singer DS: Repression of MHC class I gene promoter activity by two-exon Tat of HIV. Science 260:1320, 1993
18. Taylor JP, Cupp C, Diaz A, Chowdhuhury M, Khalili K, Jimenez SA, Amini SA: Activation of expression gene coding for extracellular matrix proteins in Tat-producing glioblastoma cells. Proc Natl Acad Sci USA 89:9617, 1992
19. Ensoli B, Buonaguro L, Barillari G, Fiorelli V, Gentelman R, Morgan RA, Wingfield P, Gallo RC: Release, uptake, and effects of extracellular human immunodeficiency virus type 1 Tat protein on cell growth and viral transactivation. J Virol 67:277, 1993
20. Westendorp MO, Frank R, Ochsenbauer C, Stricker K, Dhein J, Walczak H, Debatin KM, Krammer PH: Sensitization of T cells to CD95-mediated apoptosis by HIV-1 Tat and gp 120. Nature 375:497, 1995
21. Lotz M, Clark-Lewis I, Ganu I: HIV-transactivatior Tat induces proliferation and TGF beta expression in human articular chondrocyes. J Cell Biol 245:365, 1994
22. Barillari G, Buonaguro L, Fiorelli V, Hoffman J, Michaels F, Gallo RC, Ensoli B: Effects of cytokines from activated immune cells on vascular cell growth and HIV-1 gene expression: Implications for AIDS-Kaposi's sarcoma pathogenesis. J Immunol 149:3727, 1992
23. Hofman FM, Dohadwala MM, Wright AD, Hinton DR, Walker SM: Exogenous tat protein activates central nervous system-derived endothelial cells. J Neuroimmunol 54:19, 1994
24. Albini A, Benelli R, Presta M, Rusnati M, Ziche M, Rubartelli A, Paglialunga G, Bussolino F, Noonan D: HIV-1 tat protein is a heparin-binding angiogenic growth factor. Oncogene 12:289, 1996
25. Ensoli B, Gendelman R, Markham P, Fiorelli V, Colombini S, Ratfeld M, Cafaro A, Chang H, Brady JN, Gallo RC: In vitro and in vivo evidence that basic fibroblast growth factor and human immunodeficiency virus type-1 Tat protein synergize in inducing Kaposi's sarcoma development. Nature 371:674, 1994
26. Lafrenie RM, Wahl LM, Epstein JS, Hewlett IK, Yamada KM, Dhawan S: HIV-1-Tat modulates the function of monocytes and alters their interactions with mtcrovessel endothelial cells. J Immunol 156:1638. 1996
27. Lafrenie RM, Wahl LM, Epstein JS, Hewelett IK, Yamada KM, Dhawan S: HIV-1-Tat protein promotes chemotaxis and invasive behaviour by monocytes. J Immunol 157:974, 1996
28. Terman BI, Carrion ME, Kovacs E, Rasmussen BA, Eddy RL, Shows TB: Identification of a new endothelial cell growth factor receptor tyrosine kinase. Oncogene 6:1677, 1991
29. Millauer B, Wizgmann-Voos S, Schnurch H, Martinez R, Moller NPH, Risau W, Ulrich A: High affinity VEGF binding and developmental expression suggest Flk-1 as a major regulator of vasculogenesis and angiogenesis. Cell 72:835, 1993
30. Albini A, Soldi R, Giunciuglio D, Giraudo E, Benelli R, Primo L, Noonan D, Salio M, Camussi G, Rockl W, Bussolino F: The angiogenesis induced by HIV-1 Tat protein is mediated by the Flk-1/KDR receptor on vascular endothelial cells. Nat Med 2:1371, 1996
31. Ferrara N, Houck K, Jakerman L, Leug DW: Molecular and biological properties of the vascular endothelial growth factor family of proteins. Endocrinol Rev 13:18, 1992
32. Kenneth AT: Vascular endothelial growth factor, a potent and selective angiogenic agent. J Biol Chem 271:603, 1996
33. De Vries C, Escobedo JA, Ueno H, Houck K, Ferrara N, Williams LT: The fms-like tyrosine kinase, a receptor for vascular endothelial growth factor. Science 255:989, 1992
34. Clauss M, Gerlach M, Gerlach H, Brett J, Wang F, Familletti PC, Pan YCE, Olander JV, Connolly DT, Stern D: Vascular permeability factor: A tumor-derived polypeptide that induces endothelial cell and monocyte procoagulant activity, and promotes monocyte migration. J Exp Med 172:1535, 1990
35. 165 receptor. Blood 87:3336, 1996
36. Clauss M, Weich H, Breier G, Knies U, Wolfgang R, Waltenberg J, Risau W: The vascular endothelial growth factor receptor Fit-1 mediates biological activities. Implication for a functional role of placenta growth factor in monocyte activation and chemotaxis. J Biol Chem 271:17629, 1996
37. Sozzani S, Luini W, Molino M, J'lek P, Bottazzi B, Cerletti C, Matsushima K, Mantovani A: The signal transduction pathway involved in the migration induced by a monocyte chemotactic cytokine. J Immunol 147:2215, 1991
38. Falk W, Goodwin RH Jr, Leonard EJ: A 48-well microchemotaxis assembly for rapid and accurate measurement of leukocyte migration. J Immunol Methods 33:239, 1980
39. Locati M, Zhou D, Luini W, Evangelista V, Mantovani A, Sozzani S: Rapid induction of arachidonic acid release by monocyte chemotactic protein-1 and related chemokines - Role of Ca2+ influx, synergism with platelet-activating factor and significance for chemotaxis. J Biol Chem 269:4746, 1994
40. Wilkinson PC: Cell locomotion and chemotaxis: Basic concepts and methodological approaches. Methods 10:74, 1996
41. McPhail LC, Harvath L: Signal transduction in neutrophil oxidative metabolism and chemotaxis, in Wheeler JG, Ahramson J (ed): The Natural Immune System: The Neutrophil. Oxford, UK, Oxford, 1993, p 63
42. Murphy PM: The molecular biology of leukocyte chemoattractant receptors. Annu Rev Immunol 12:593, 1994
43. Kendall RL, Thomas KA: Inhibition of vascular endothelial growth factor activity by an endogenously encoded soluble receptor. Proc Natl Acad Sci USA 90:10705, 1993
44. Shen H, Clauss M, Ryan J, Schmidt AM, Tijburg P, Borden L, Connoly D, Stern D, Kao J: Characterization of vascular permeability factor/vascular endothelial growth factor receptors on mononuclear phagocytes. Blood 81:2767, 1993
45. Brake DA, Debouck C, Biesecher G: Identification of an ArgGly-Asp (RGD) cell adhesion site in human immunodeficiency virus type 1 transactivation protein, tat. J Cell Biol 111:1275, 1990
46. Waltemberger J, Claesson-Welsh L, Siegbahn A, Shibuyha M, Heldin CH: Differential signal transduction properties of KDR and Flt 1, two receptors for vascular endothelial growth factor. J Biol Chem 269:26988, 1994
47. Seetharam L, Gotoh N, Maru Y, Neufeld G, Yamaguchi S, Shybuya: A unique signal transduction from FLT tyrosine kinase, a receptor for vascular endothelial growth factor VEGF. Oncogene 10:135, 1995
48. + T lymphocytes. J Immunol 157:2216, 1996
49. Poli G, Bottazzi B, Acero R, Bersani L, Rossi V, Introna M, Lazzarin A, Galli M, Mantovani A: Monocyte function in intravenous drug abusers with lymphadenopathy syndrome and in patients with acquired immunodeficiency syndrome: Selective impairment of chemotaxis. Clin Exp Immunol 62:136, 1985
50. Gabrilovich DI, Chen HL, Giris KR, Cunningham HT, Meny GM, Nadaf S, Kavanaugh D, Carbone DP: Production of vascular endothelial growth by human tumors inhibits the functional maturation of dendritic cells. Nat Med 2:1096, 1996