Inefficient phospholipase C activation and reduced Lck expression characterize the signaling defect of umbilical cord T lymphocytes

Journal of Immunology

Volumn 163, Issue 5, 1999, Pages 2416-2424

  Miscia, Sebastiano ^a,b   Di Baldassarre, Angela ^a   Sabatino, Giuseppe ^b   Bonvini, Ezio ^e   Rana, Rosa Alba ^a   Vitale, Marco ^d   Di Valerio, Valentina ^a   Manzoli, Francesco Antonio ^c  

^a Istituto di Morfologia Umana Normale   (Italy)

^b UNIVERSITY OF CHIETI   (Italy)

^c UNIVERSITY OF BOLOGNA   (Italy)

^d UNIVERSITY OF BRESCIA   (Italy)

^e CENTER FOR BIOLOGICS EVALUATION AND RESEARCH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALUMINUM FLUORIDE; CALCIUM; CD3 ANTIGEN; IONOMYCIN; PERVANADATE; PHORBOL 13 ACETATE 12 MYRISTATE; PHOSPHOLIPASE C; PROTEIN KINASE C; PROTEIN TYROSINE KINASE;

ADULT; ARTICLE; CALCIUM MOBILIZATION; CONTROLLED STUDY; ENZYME ACTIVATION; HUMAN; HUMAN CELL; IMMUNE RESPONSE; NEWBORN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; T LYMPHOCYTE; UMBILICAL CORD;

ADULT; ANTIGENS, CD3; CELL DIVISION; CELLS, CULTURED; ENZYME ACTIVATION; FETAL BLOOD; FLOW CYTOMETRY; HUMANS; IONOMYCIN; ISOENZYMES; LYMPHOCYTE SPECIFIC PROTEIN TYROSINE KINASE P56(LCK); PHOSPHATIDYLINOSITOLS; PHOSPHOLIPASE C; PROTEIN-TYROSINE KINASES; SIGNAL TRANSDUCTION; T-LYMPHOCYTE SUBSETS; TETRADECANOYLPHORBOL ACETATE; VANADATES;

EID: 0033198228     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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