-
2
-
-
0026534558
-
The substituted amphetamines 3,4-methylenedioxymethamphetamine, methamphetamine, p-chloroamphetamine and fenfluramine induce 5-hydroxytryptamine release via a common mechanism blocked by fluoxetine and cocaine
-
Berger UV, Gu XF, Azmitia EC. 1992. The substituted amphetamines 3,4-methylenedioxymethamphetamine, methamphetamine, p-chloroamphetamine and fenfluramine induce 5-hydroxytryptamine release via a common mechanism blocked by fluoxetine and cocaine. Eur J Pharmacol 215:153-160.
-
(1992)
Eur J Pharmacol
, vol.215
, pp. 153-160
-
-
Berger, U.V.1
Gu, X.F.2
Azmitia, E.C.3
-
3
-
-
0028773367
-
Secondary amine analogues of 3-β-(4′-substituted phenyl) tropane-2β-carboxylic acid esters and N-norcocaine exhibit enhanced affinity for serotonin and norepinephrine transporters
-
Boja JW, Kuhar MJ, Kopajtic T, Yang E, Abraham P, Lewin AH, Carrol FI. 1995. Secondary amine analogues of 3-β-(4′-substituted phenyl) tropane-2β-carboxylic acid esters and N-norcocaine exhibit enhanced affinity for serotonin and norepinephrine transporters. J Med Chem 37:1220-1230.
-
(1995)
J Med Chem
, vol.37
, pp. 1220-1230
-
-
Boja, J.W.1
Kuhar, M.J.2
Kopajtic, T.3
Yang, E.4
Abraham, P.5
Lewin, A.H.6
Carrol, F.I.7
-
4
-
-
0028856659
-
Age-dependent sensitivity of rats to long-term effects of the serotonergic neurotoxicant (±)-3,4-methylenedioxymethylamphetamine (MDMA) correlates with the magnitude of the MDMA-induced thermal response
-
Broening HW, Bowyer JF, Slikker W Jr. 1995. Age-dependent sensitivity of rats to long-term effects of the serotonergic neurotoxicant (±)-3,4-methylenedioxymethylamphetamine (MDMA) correlates with the magnitude of the MDMA-induced thermal response. J Pharmacol Exp Ther 275:325-333.
-
(1995)
J Pharmacol Exp Ther
, vol.275
, pp. 325-333
-
-
Broening, H.W.1
Bowyer, J.F.2
Slikker W., Jr.3
-
5
-
-
0018938175
-
Antihistamines effect on synaptosomal uptake of serotonin, norepinephrine and dopamine
-
Brown PA, Vernikos J. 1980. Antihistamines effect on synaptosomal uptake of serotonin, norepinephrine and dopamine. Eur J Pharmacol 65:89-92.
-
(1980)
Eur J Pharmacol
, vol.65
, pp. 89-92
-
-
Brown, P.A.1
Vernikos, J.2
-
6
-
-
0027978346
-
CuZn-superoxide dismutase (CuZnSOD) transgenic mice show resistance to the lethal effects of methylenedioxyamphetamine (MDA) and of methylenedioxymethamphetamine (MDMA)
-
Cadet JL, Ladenheim B, Baum I, Carlson E, Epstein C. 1994. CuZn-superoxide dismutase (CuZnSOD) transgenic mice show resistance to the lethal effects of methylenedioxyamphetamine (MDA) and of methylenedioxymethamphetamine (MDMA). Brain Res 655: 259-262.
-
(1994)
Brain Res
, vol.655
, pp. 259-262
-
-
Cadet, J.L.1
Ladenheim, B.2
Baum, I.3
Carlson, E.4
Epstein, C.5
-
7
-
-
0029126705
-
Superoxide radicals mediate the biochemical effects of methylenedioxymethamphetamine (MDMA): Evidence from using CuZn-superoxide dismutase transgenic mice
-
Cadet JL, Ladenheim B, Hirata H, Rothman RB, Ali S, Carlson E, Epstein C. 1995. Superoxide radicals mediate the biochemical effects of methylenedioxymethamphetamine (MDMA): evidence from using CuZn-superoxide dismutase transgenic mice. Synapse 21:169-176.
-
(1995)
Synapse
, vol.21
, pp. 169-176
-
-
Cadet, J.L.1
Ladenheim, B.2
Hirata, H.3
Rothman, R.B.4
Ali, S.5
Carlson, E.6
Epstein, C.7
-
8
-
-
0014546172
-
Central and peripheral monoaminergic membrane-pump blockade by some addictive analgesics and antihistamines
-
Carlsson A, Lindqvist M. 1969. Central and peripheral monoaminergic membrane-pump blockade by some addictive analgesics and antihistamines. J Pharm Pharmacol 21:460-464.
-
(1969)
J Pharm Pharmacol
, vol.21
, pp. 460-464
-
-
Carlsson, A.1
Lindqvist, M.2
-
9
-
-
0028895035
-
Body temperature effect on methylenedioxymethamphetamine-induced acute decrease in tryptophan hydroxylase activity
-
Che S, Johnson M, Hanson GR, Gibb JW. 1995. Body temperature effect on methylenedioxymethamphetamine-induced acute decrease in tryptophan hydroxylase activity. Eur J Pharmacol 293:447-453.
-
(1995)
Eur J Pharmacol
, vol.293
, pp. 447-453
-
-
Che, S.1
Johnson, M.2
Hanson, G.R.3
Gibb, J.W.4
-
10
-
-
0028658438
-
In vivo generation of hydroxyl radicals and MPTP-induced dopaminergic toxicity in the basal ganglia. In the neurobiology of NO• and •OH
-
Chiueh CC, Wu R-M, Mohanakumar KP, Sternberger LM, Frishna T, Obata T, Murphy DL. 1994. In vivo generation of hydroxyl radicals and MPTP-induced dopaminergic toxicity in the basal ganglia. In the neurobiology of NO• and •OH. Ann NY Acad Sci 738:15-25.
-
(1994)
Ann Ny Acad Sci
, vol.738
, pp. 15-25
-
-
Chiueh, C.C.1
Wu, R.-M.2
Mohanakumar, K.P.3
Sternberger, L.M.4
Frishna, T.5
Obata, T.6
Murphy, D.L.7
-
11
-
-
0031886643
-
Fenfluramine and norfenfluramine levels in brain microdialysate, brain tissue and plasma of rats administered doses of d-fenfluramine known to deplete 5-hydroxytryptamine levels in brain
-
Clausing P, Newport GD, Bowyer JF. 1998. Fenfluramine and norfenfluramine levels in brain microdialysate, brain tissue and plasma of rats administered doses of d-fenfluramine known to deplete 5-hydroxytryptamine levels in brain. J Pharmacol Exp Ther 284:618-624.
-
(1998)
J Pharmacol Exp Ther
, vol.284
, pp. 618-624
-
-
Clausing, P.1
Newport, G.D.2
Bowyer, J.F.3
-
12
-
-
0027462464
-
5-HT loss in rat brain following 3,4-methylenedioxymethamphetamine (MDMA), p-chloroamphetamine and fenfluramine administration and effects of chlormethiazole and dizocilpine
-
Colado MI, Murray TK, Green AR. 1993. 5-HT loss in rat brain following 3,4-methylenedioxymethamphetamine (MDMA), p-chloroamphetamine and fenfluramine administration and effects of chlormethiazole and dizocilpine. Br J Pharmacol 108:583-589.
-
(1993)
Br J Pharmacol
, vol.108
, pp. 583-589
-
-
Colado, M.I.1
Murray, T.K.2
Green, A.R.3
-
13
-
-
0030986255
-
In vivo evidence for free radical involvement in the degeneration of rat brain 5-HT following administration of MDMA ("ecstasy") and p-chloroamphetamine but not the degeneration following fenfluramine
-
Colado MI, O'Shea E, Granados R, Murray TK, Green AR. 1997. In vivo evidence for free radical involvement in the degeneration of rat brain 5-HT following administration of MDMA ("ecstasy") and p-chloroamphetamine but not the degeneration following fenfluramine. Br J Pharmacol 121:889-900.
-
(1997)
Br J Pharmacol
, vol.121
, pp. 889-900
-
-
Colado, M.I.1
O'Shea, E.2
Granados, R.3
Murray, T.K.4
Green, A.R.5
-
14
-
-
0023255308
-
Biochemical and histological evidence that methylenedioxymethamphetamine (MDMA) is toxic to neurons in the rat brain
-
Commins DL, Vosmer G, Virus RM, Woolverton WL, Schuster ER, Seiden LS. 1987. Biochemical and histological evidence that methylenedioxymethamphetamine (MDMA) is toxic to neurons in the rat brain. J Pharmacol Exp Ther 241:338-345.
-
(1987)
J Pharmacol Exp Ther
, vol.241
, pp. 338-345
-
-
Commins, D.L.1
Vosmer, G.2
Virus, R.M.3
Woolverton, W.L.4
Schuster, E.R.5
Seiden, L.S.6
-
15
-
-
0017744763
-
Uptake and release of 5-hydroxytryptamine by rabbit platelets. II. Kinetic analysis of inhibition by chlorpheniramine maleate
-
Cusimano VJ, Sankar DVS. 1977. Uptake and release of 5-hydroxytryptamine by rabbit platelets. II. Kinetic analysis of inhibition by chlorpheniramine maleate. Biochem Med 17:267-274.
-
(1977)
Biochem Med
, vol.17
, pp. 267-274
-
-
Cusimano, V.J.1
Sankar, D.V.S.2
-
17
-
-
0027361326
-
Long-term alteration in the central monoaminergic systems of the rat by 2,4,5-trihydroxyamphetamine, 2,4,5-trihydroxymethamphetamine and 3,4-dihydroxymethamphetamine on central tryptophan hydroxylase activity
-
Elayan I, Gibb JW, Hanson GR, Lim HK, Foltz RL, Johnson M. 1993. Long-term alteration in the central monoaminergic systems of the rat by 2,4,5-trihydroxyamphetamine, 2,4,5-trihydroxymethamphetamine and 3,4-dihydroxymethamphetamine on central tryptophan hydroxylase activity. J Pharmacol Exp Ther 265:813-817.
-
(1993)
J Pharmacol Exp Ther
, vol.265
, pp. 813-817
-
-
Elayan, I.1
Gibb, J.W.2
Hanson, G.R.3
Lim, H.K.4
Foltz, R.L.5
Johnson, M.6
-
18
-
-
0028833356
-
Role of hypothermia in the mechanism of protection against serotonergic toxicity. I. Experiments using 3,4-methylenedioxymethamphetamine, dizocilpine, CGS 19755 and NBQX
-
Farfel GM, Seiden LS. 1995. Role of hypothermia in the mechanism of protection against serotonergic toxicity. I. Experiments using 3,4-methylenedioxymethamphetamine, dizocilpine, CGS 19755 and NBQX. J Pharmacol Exp Ther 272:860-867.
-
(1995)
J Pharmacol Exp Ther
, vol.272
, pp. 860-867
-
-
Farfel, G.M.1
Seiden, L.S.2
-
19
-
-
0016800414
-
Blockade of amine depletion by nisoxetine in comparison to other uptake inhibitors
-
Fuller RW, Snoddy HD, Molly BB. 1975. Blockade of amine depletion by nisoxetine in comparison to other uptake inhibitors. Psychopharmacol Commun 1:455-464.
-
(1975)
Psychopharmacol Commun
, vol.1
, pp. 455-464
-
-
Fuller, R.W.1
Snoddy, H.D.2
Molly, B.B.3
-
21
-
-
0015859726
-
Relationship of the structure of mescaline and seven analogs to toxicity and behavior in five species of laboratory animals
-
Hardman HF, Haavik CO, Seevers MH. 1973. Relationship of the structure of mescaline and seven analogs to toxicity and behavior in five species of laboratory animals. Toxicol Appl Pharmacol 25:299-309.
-
(1973)
Toxicol Appl Pharmacol
, vol.25
, pp. 299-309
-
-
Hardman, H.F.1
Haavik, C.O.2
Seevers, M.H.3
-
22
-
-
0026680529
-
Toxicity and deaths from 3,4-methylenedioxymethamphetamine ("ecstasy")
-
Henry JA, Jeffreys KJ, Dawling S. 1992. Toxicity and deaths from 3,4-methylenedioxymethamphetamine ("ecstasy"). Lancet 340:384-387.
-
(1992)
Lancet
, vol.340
, pp. 384-387
-
-
Henry, J.A.1
Jeffreys, K.J.2
Dawling, S.3
-
23
-
-
0025121255
-
Metabolism of methylenedioxymethamphetamine: Formation of dihydroxymethamphetamine and a quinone identified as its glutathione adduct
-
Hiramatsu M, Kumagai Y, Unger SE, Cho AK. 1990. Metabolism of methylenedioxymethamphetamine: formation of dihydroxymethamphetamine and a quinone identified as its glutathione adduct. J Pharmacol Exp Ther 254:521-527.
-
(1990)
J Pharmacol Exp Ther
, vol.254
, pp. 521-527
-
-
Hiramatsu, M.1
Kumagai, Y.2
Unger, S.E.3
Cho, A.K.4
-
24
-
-
0028816462
-
Mepyramine, a histamine H1 receptor antagonist, inhibits the metabolic activity of rats and human P4502D forms
-
Hiroi T, Ohishi N, Imaoka S, Yabusaki Y, Fukui H, Funae Y. 1995. Mepyramine, a histamine H1 receptor antagonist, inhibits the metabolic activity of rats and human P4502D forms. J Pharmacol Exp Ther 272:939-944.
-
(1995)
J Pharmacol Exp Ther
, vol.272
, pp. 939-944
-
-
Hiroi, T.1
Ohishi, N.2
Imaoka, S.3
Yabusaki, Y.4
Fukui, H.5
Funae, Y.6
-
25
-
-
0015338517
-
The temperature dependence of the components of the hepatic microsomal mixed-function oxidases
-
Holtzman JL, Carr ML. 1972. The temperature dependence of the components of the hepatic microsomal mixed-function oxidases. Arch Biochem Biophys 150:227-234.
-
(1972)
Arch Biochem Biophys
, vol.150
, pp. 227-234
-
-
Holtzman, J.L.1
Carr, M.L.2
-
26
-
-
0024383159
-
3,4-Methylenenedioxymethamphetamine ("Ecstasy") selectively destroys brain serotonin terminals in rhesus monkeys
-
Insel TR, Battaglia G, Johannessen JN, Marra S, De Souza EB. 1989. 3,4-Methylenenedioxymethamphetamine ("Ecstasy") selectively destroys brain serotonin terminals in rhesus monkeys. J Pharmacol Exp Ther 249:713-720.
-
(1989)
J Pharmacol Exp Ther
, vol.249
, pp. 713-720
-
-
Insel, T.R.1
Battaglia, G.2
Johannessen, J.N.3
Marra, S.4
De Souza, E.B.5
-
27
-
-
0008267197
-
Drug metabolism in hypothermia. II. C14 atropine uptake, metabolism and excretion by the isolated perfused rat liver
-
Kalser SC, Kelvington EJ, Randolph MM, Santonmenna DM. 1965. Drug metabolism in hypothermia. II. C14 atropine uptake, metabolism and excretion by the isolated perfused rat liver. J Pharmacol Exp Ther 147:260-269.
-
(1965)
J Pharmacol Exp Ther
, vol.147
, pp. 260-269
-
-
Kalser, S.C.1
Kelvington, E.J.2
Randolph, M.M.3
Santonmenna, D.M.4
-
28
-
-
0003110629
-
Brain temperature alters hydroxyl radical production during cerebral ischemia/reperfusion in rats
-
Kil YH, Zhang J, Piantadosi CA. 1996. Brain temperature alters hydroxyl radical production during cerebral ischemia/reperfusion in rats. J Cerebral Blood Metab 16:100-106.
-
(1996)
J Cerebral Blood Metab
, vol.16
, pp. 100-106
-
-
Kil, Y.H.1
Zhang, J.2
Piantadosi, C.A.3
-
29
-
-
0032531095
-
Dopamine inactivates tryptophan hydroxylase and forms a redox-cycling quinoprotein: Possible endogenous toxin to serotonin neurons
-
Kuhn DM, Arthur R Jr. 1998. Dopamine inactivates tryptophan hydroxylase and forms a redox-cycling quinoprotein: possible endogenous toxin to serotonin neurons. J Neurosci 15:7111-7117.
-
(1998)
J Neurosci
, vol.15
, pp. 7111-7117
-
-
Kuhn, D.M.1
Arthur R., Jr.2
-
30
-
-
0030610339
-
2 production during ischemia and reperfusion: A microdialysis study in the gerbil hippocampus
-
2 production during ischemia and reperfusion: a microdialysis study in the gerbil hippocampus. Neurosci Lett 222:91-94.
-
(1997)
Neurosci Lett
, vol.222
, pp. 91-94
-
-
Lei, B.1
Adachi, N.2
Arai, T.3
-
32
-
-
0030438476
-
Coadministration of MDMA with drugs that protect against MDMA neurotoxicity produces different effects on body temperature in the rat
-
Malberg JE, Sabot KE, Seiden LS. 1996. Coadministration of MDMA with drugs that protect against MDMA neurotoxicity produces different effects on body temperature in the rat. J Pharmacol Exp Ther 278:258-267.
-
(1996)
J Pharmacol Exp Ther
, vol.278
, pp. 258-267
-
-
Malberg, J.E.1
Sabot, K.E.2
Seiden, L.S.3
-
33
-
-
0028812803
-
The effect of acute MDMA administration on body temperature, serum corticosterone and neurotransmitter concentrations in male and female rats
-
McNamara MG, Kelly JP, Leonard BE. 1995. The effect of acute MDMA administration on body temperature, serum corticosterone and neurotransmitter concentrations in male and female rats. Human Psychopharmacol 10:373-383.
-
(1995)
Human Psychopharmacol
, vol.10
, pp. 373-383
-
-
McNamara, M.G.1
Kelly, J.P.2
Leonard, B.E.3
-
35
-
-
0015031927
-
Blockade of p-chloromethamphetamine induced 5-hydroxytryptamine depletion by chlorimipramine, chlorpheniramine and meperidine
-
Meek JL, Fuxe K, Carlsson A. 1971. Blockade of p-chloromethamphetamine induced 5-hydroxytryptamine depletion by chlorimipramine, chlorpheniramine and meperidine. Biochem Pharmacol 20:707-709.
-
(1971)
Biochem Pharmacol
, vol.20
, pp. 707-709
-
-
Meek, J.L.1
Fuxe, K.2
Carlsson, A.3
-
36
-
-
0027964301
-
Environment-, drug- and stress-induced alterations in body temperature affect the neurotoxicity of substituted amphetamines in the C57BL/6J mouse
-
Miller DB, O'Callaghan JP. 1994. Environment-, drug- and stress-induced alterations in body temperature affect the neurotoxicity of substituted amphetamines in the C57BL/6J mouse. J Pharmacol Exp Ther 270:752-760.
-
(1994)
J Pharmacol Exp Ther
, vol.270
, pp. 752-760
-
-
Miller, D.B.1
O'Callaghan, J.P.2
-
37
-
-
0023898060
-
Elevation of serum prolactin and cortisone concentrations in the rat after the administration of 3,4-methylenedioxymethamphetamine
-
Nash KF Jr, Meltzer HY, Gudelsky GA. 1988. Elevation of serum prolactin and cortisone concentrations in the rat after the administration of 3,4-methylenedioxymethamphetamine. J Pharmacol Exp Ther 245:873-879.
-
(1988)
J Pharmacol Exp Ther
, vol.245
, pp. 873-879
-
-
Nash K.F., Jr.1
Meltzer, H.Y.2
Gudelsky, G.A.3
-
39
-
-
0031448992
-
Scavenging of hydroxyl radicals but not peroxynitrite by inhibitors and substrates of nitric oxide syntheses
-
Rehman A, Whiteman M, Halliwell B. 1997. Scavenging of hydroxyl radicals but not peroxynitrite by inhibitors and substrates of nitric oxide syntheses. Br J Pharmacol 122:1072-1705.
-
(1997)
Br J Pharmacol
, vol.122
, pp. 1072-1705
-
-
Rehman, A.1
Whiteman, M.2
Halliwell, B.3
-
40
-
-
0027174387
-
Identification of a GBR12935 homolog, LR1111, which is over 4,000-fold selective for dopamine transporter, relative to serotonin and norepinephrine transporters
-
Rothman RB, Lewis B, Dersch C, Xu H, Radesca L, de Costa BR, Rice KC, Kilburn RB, Akunne HC, Pert A. 1993. Identification of a GBR12935 homolog, LR1111, which is over 4,000-fold selective for dopamine transporter, relative to serotonin and norepinephrine transporters. Synapse 14:34-39.
-
(1993)
Synapse
, vol.14
, pp. 34-39
-
-
Rothman, R.B.1
Lewis, B.2
Dersch, C.3
Xu, H.4
Radesca, L.5
De Costa, B.R.6
Rice, K.C.7
Kilburn, R.B.8
Akunne, H.C.9
Pert, A.10
-
41
-
-
0023163857
-
Neurotoxicity of the psychedelic amphetamine, methylenedioxymethamphetamine
-
Schmidt CJ. 1987. Neurotoxicity of the psychedelic amphetamine, methylenedioxymethamphetamine. J Pharmacol Exp Ther 240:1-7.
-
(1987)
J Pharmacol Exp Ther
, vol.240
, pp. 1-7
-
-
Schmidt, C.J.1
-
42
-
-
0022911033
-
The effects of 3,4-methylenedioxymethamphetamine (MDMA) and 3,4-methylenedioxyamphetamine (MDA) on monoaminergic systems in the rat brain
-
Stone DM, Stahl DC, Hanson GR, Gibb JW. 1986. The effects of 3,4-methylenedioxymethamphetamine (MDMA) and 3,4-methylenedioxyamphetamine (MDA) on monoaminergic systems in the rat brain. Eur J Pharmacol 128:41-48.
-
(1986)
Eur J Pharmacol
, vol.128
, pp. 41-48
-
-
Stone, D.M.1
Stahl, D.C.2
Hanson, G.R.3
Gibb, J.W.4
-
43
-
-
0030798269
-
The effect of salicylate on 3,4-methylenedioxymethamphetamine (MDMA)-induced neurotoxicity in rats
-
Yeh SY. 1997a. The effect of salicylate on 3,4-methylenedioxymethamphetamine (MDMA)-induced neurotoxicity in rats. Pharmacol Biochem Behav 58:701-708.
-
(1997)
Pharmacol Biochem Behav
, vol.58
, pp. 701-708
-
-
Yeh, S.Y.1
-
44
-
-
0345497992
-
Chlorpheniramine protects against 3,4-methylenedioxymethamphetamine-induced depletion of serotonin in rats
-
Yeh SY. 1997b. Chlorpheniramine protects against 3,4-methylenedioxymethamphetamine-induced depletion of serotonin in rats. Neurosci Abstr 27:21-41.
-
(1997)
Neurosci Abstr
, vol.27
, pp. 21-41
-
-
Yeh, S.Y.1
-
45
-
-
0033103959
-
N-tert-butyl-alpha-phenylnitrone protects against 3,4-methylenedioxymethamphetamine-induced depletion of serotonin in rats
-
Yeh SY. 1999a. N-tert-butyl-alpha-phenylnitrone protects against 3,4-methylenedioxymethamphetamine-induced depletion of serotonin in rats. Synapse 31:169-177.
-
(1999)
Synapse
, vol.31
, pp. 169-177
-
-
Yeh, S.Y.1
-
46
-
-
0033563984
-
Effects of antihistamines on fenfluramiine-induced depletion of indoles in the brain of rats
-
Yeh, SY. 1999b. Effects of antihistamines on fenfluramiine-induced depletion of indoles in the brain of rats. Synapse, 32:301-311.
-
(1999)
Synapse
, vol.32
, pp. 301-311
-
-
Yeh, S.Y.1
|