Self-association of Purα is mediated by RNA

Journal of Cellular Biochemistry

Volumn 74, Issue 3, 1999, Pages 334-348

  Gallia, Gary L ^a   Darbinian, Nune ^a   Johnson, Edward M ^b   Khalili, Kamel ^a  

^a DREXEL UNIVERSITY COLLEGE OF MEDICINE   (United States)

^b MOUNT SINAI SCHOOL OF MEDICINE   (United States)

Author keywords

HIV 1 tat protein; Pur ; Replication; RNA; Self association; Transcription

Indexed keywords

AMINO ACID; CELL PROTEIN; DNA; DNA BINDING PROTEIN; GLUTATHIONE TRANSFERASE; LEUCINE; PROTEIN PUR ALPHA; RNA; TRANSACTIVATOR PROTEIN; UNCLASSIFIED DRUG; HYBRID PROTEIN; PURA PROTEIN, HUMAN; RNA BINDING PROTEIN; TRANSCRIPTION FACTOR;

ARTICLE; CONTROLLED STUDY; DNA REPLICATION; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; MOLECULAR CLONING; PRIORITY JOURNAL; PROTEIN DNA INTERACTION; PROTEIN DOMAIN; PROTEIN PROTEIN INTERACTION; TRANSCRIPTION REGULATION; AMINO ACID SEQUENCE; BIOLOGICAL MODEL; CELL CULTURE; CHEMISTRY; DRUG ANTAGONISM; GENETIC TRANSFECTION; METABOLISM; MOLECULAR GENETICS; PHYSIOLOGY; SEQUENCE HOMOLOGY;

AMINO ACID SEQUENCE; DNA; DNA-BINDING PROTEINS; GENE PRODUCTS, TAT; HUMANS; MODELS, GENETIC; MOLECULAR SEQUENCE DATA; RECOMBINANT FUSION PROTEINS; RNA; RNA-BINDING PROTEINS; SEQUENCE HOMOLOGY, AMINO ACID; TRANSCRIPTION FACTORS; TRANSFECTION; TUMOR CELLS, CULTURED;

EID: 0033181328     PISSN: 07302312     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-4644(19990901)74:3<334::AID-JCB3>3.0.CO;2-O     Document Type: Article

References (26)

1. Bergemann AD, Johnson EM. 1992. The HeLa pur factor binds single-stranded DNA at a specific element conserved in gene flanking regions and origins of DNA replication. Mol Cell Biol 12:1257-1265.
2. Bergemann AD, Ma ZW, Johnson EM. 1992. Sequence of cDNA comprising the human pur gene and sequence-specific single-stranded-DNA-binding properties of the encoded protein. Mol Cell Biol 12:5673-5682.
3. Chang C-F, Chen NN, Muralidharan V, Zoltick PW, Johnson EM, Khalili K. 1996. Evidence that DNA replication of human neurotropic JC virus DNA in glial cells is regulated by a sequence-specific single-stranded DNA-bind-ing protein Purα. J Virol 70:4150-4156.
4. Chen N, Khalili K. 1995. Transcriptional regulation of human JC polyomavirus promoters by cellular proteins YB-1 and Purα in glial cells. J Virol 69:5843-5848.
5. Chen NN, Chang CF, Gallia GL, Kerr DA, Johnson EM, Krachmarov CP, Barr SM, Frisque RJ, Bollag B, Khalili K. 1995. Cooperative action of cellular proteins YB-1 and Purα with the tumor antigen of the human JC polyomavirus determines their interaction with the viral lytic control element. Proc Natl Acad Sci USA 92:1087-1091.
6. Chepenik LG, Tretiakova AP, Krachmarov CP, Johnson EM, Khalili K. 1998. The single-stranded DNA binding protein, Purα, binds HIV-1 TAR RNA and activates HIV-1 transcription. Gene 210:37-44.
7. Du Q, Tomkinson AE, Gardner PD. 1997. Transcriptional regulation of neuronal nicotinic acetylcholine receptor genes. J Biol Chem 272:14990-14995.
8. Haas S, Gordon J, Khalili K. 1993. A developmentally regulated DNA-binding protein from mouse brain stimulates myelin basic protein gene expression. Mol Cell Biol 13:3103-3112.
9. Haas S, Thatikunta P, Steplewski A, Johnson EM, Khalili K, Amini S. 1995. A 39-kD DNA-protein from mouse brain stimulates transcription of myelin basic protein gene in oligodendrocytic cells. J Cell Biol 130:1171-1179.
10. Herault Y, Chatelain G, Brum G, Mickel D. 1995. RNA-dependent DNA binding activity of the Pur factor, potentially involved in DNA replication and gene transcription. Gene Exp 4:85-93.
11. Ishizaki J, Nevins JR, Sullenger BA. 1996. Inhibition of cell proliferation by an RNA ligant that selectively blocks E2F function. Nat Med 2:1386-1389.
12. Johnson EM, Chen PL, Krachmarov CP, Barr SM, Kanovsky M, Ma ZW, Lee WH. 1995. Association of human Purα, with the retinoblastoma protein, Rb, regulates binding to the single-stranded DNA Purα recognition element. J Biol Chem 270:24352-24360.
13. Jurk M, Weissinger F, Lottspeich F, Schwarz U, Winnacker EL. 1996. Characterization of the single-strand-speciflc BPV-1 origin binding protein, SPSF I, as the HeLa Purα factor. Nucleic Acids Res 24:2799-2806.
14. Kelm RJ Jr, Elder PK, Strauch AR, Getz MJ. 1997. Sequence of cDNAs encoding components of vascular actin single-stranded DNA-binding factor 2 establish identity to Purα and Purβ. J Biol Chem 272:26727-26733.
15. Krachmarov CP, Chepenik LG, Barr-Vagell S, Khalili K, Johnson EM. 1995. Activation of the JC virus tat-responsive transcriptional control element by association of the tat protein of human immunodeficiency virus 1 with cellular protein Purα. Proc Natl Acad Sci USA 93:14112-14117.
16. Lai JS, Herr W. 1992. Ethidium bromide provides a simple tool for identifying genuine DNA-independent protein associations. Proc Natl Acad Sci USA 89:6958-6962.
17. Lezon-Geyda KA, Najfeld V, Johnson EM. 1997. The PURA gene, encoding the single-stranded DNA-binding protein Purα, as a marker for 5q31 alteration in myeloproliferative disorders, a potential early step in induction of AML. FASEB 11:A100.
18. Ma ZW, Pejovic T, Najfeld V, Ward DC, Johnson EM. 1995. Localization of PURA, the gene encoding the sequence-specific single-stranded-DNA-binding protein Purα, to chromosome band 5q31. Cytogenet Cell Genet 71:64-67.
19. Muralidharan V, Tretiakova A, Steplewski A, Haas S, Amini S, Johnson E, Khalili K. 1997. Evidence for inhibition of MyEF-2 binding to MBP promoter by MEF-1/Purα. J Cell Biochem 66:524-531.
20. Osugi T, Hidekazu T, Kuo CH, Do E, Irie Y, Miki N. 1996. Involvement of a single-stranded DNA binding proteins, ssCRE-BP/Purα, in morphine dependence. FEBS 391: 11-16.
21. Smith DB, Johnson KS. 1988. Single-step purification of polypeptides expressed in Escherichia coli as fusions with glutathione-S-transferase. Gene 67:31-40.
22. Tada H, Khalili K. 1992. A novel sequence-specific DNA-binding protein, LCP-1, interacts with single-stranded DNA and differentially regulates early gene expression of the human neurotropic JC virus. J Virol 66:6885-6892.
23. Tjian R, Maniatis T. 1994. Transcriptional activation: a complex puzzle with few easy pieces. Cell 77:5-8.
24. Tretiakova A, Gallia GL, Shcherbik N, Johnson EM, Khalili K. 1998. Association of Purα with 7SL RNA determines its binding ability to the MBP promoter DNA sequence. J Biol Chem 273:22241-22247.
25. Weinberg RA. 1995. The retinoblastoma protein and cell cycle control. Cell 81:323-330.
26. Zambrano N, DeRenzis S, Minopoli G, Faraonio R, Donini V, Scaloni A, Cimino F, Russo T. 1997. DNA-binding protein Purα and transcription factor YY1 function as transcription activator of the neuron-specific FE65 gene promoter. Biochem J 328:293-300.