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Localization of an ataxia-telangiectasia gene to a ∼500 kb interval on chromosome 11q23.1: Linkage analysis of 176 families in an international consortium
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A single ataxia-telangiectasia gene with a product similar to PI-3 kinase
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Ataxia telangiectasia mutant protein activates c-Abl tyrosine kinase in response to ionizing radiation
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Interaction between ATM protein and c-abl in response to DNA damage
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Shafman, T., Khanna, K. K., Kedar, P., Spring, K., Kozlov, S., Yen, T., Hobson, K., Gatei, M., Zhang, N., Watters, D., Egerton, M., Shiloh, Y., Kharbanda, S., Kufe, D., and Lavin, M. F. Interaction between ATM protein and c-abl in response to DNA damage. Nature (Lond.), 387: 520-523, 1997.
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Enhanced phosphorylation of p53 by ATM in response to DNA damage
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Activation of the ATM kinase by ionizing radiation and phosphorylation of p53
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ATM associates with and phosphorylates p53: Mapping the region of interaction
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Khanna, K. K., Keating, K. E., Kozlov, S., Scott, S., Gatei, M., Hobson, K., Taya, Y., Gabrielli, B., Chan, D., Lees-Miller, S. P., and Lavin, M. F. ATM associates with and phosphorylates p53: mapping the region of interaction. Nat. Genet., 20: 398-400, 1998.
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Mortality and cancer incidence in 263 patients with ataxia-telangiectasia
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Heterozygous ATM mutations do not contribute to early onset of breast cancer
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The gene for the ataxia-telangiectasia variant, Nijmegen Breakage syndrome, maps to a 1-cM interval on chromosome 8q21
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