Impaired mammary gland development in Cyl-1(-/-) mice during pregnancy and lactation is epithelial cell autonomous

Developmental Biology

Volumn 212, Issue 1, 1999, Pages 1-11

  Fantl, Vera ^a   Edwards, Paul A W ^b   Steel, Jennifer H ^a   Vonderhaar, Barbara K ^c   Dickson, Clive ^a  

^a IMPERIAL CANCER RESEARCH FUND   (United Kingdom)

^b UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^c NATIONAL CANCER INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIN D1; MILK PROTEIN; PROGESTERONE RECEPTOR; PROLACTIN; STAT5 PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BREAST DEVELOPMENT; BREAST EPITHELIUM; CONTROLLED STUDY; EPITHELIUM CELL; LACTATION; MAMMARY GLAND; MILK PRODUCTION; MOUSE; NONHUMAN; PHENOTYPE; PREGNANCY; PRIORITY JOURNAL; PROLACTIN RELEASE; PROLACTIN SYNTHESIS; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; RAT; TISSUE TRANSPLANTATION;

EID: 0033179052     PISSN: 00121606     EISSN: None     Source Type: Journal    
DOI: 10.1006/dbio.1999.9329     Document Type: Article

References (44)

1. Altucci L., Addeo R., Cicatiello L., Dauvois S., Parker M. G., Truss M., Beato M., Sica V., Bresciani F., Weisz A. 17-β-Estradiol induces cyclin D1 gene-transcription, p36(D1)-p34(cdk4) complex activation and p105(rb) phosphorylation during mitogenic stimulation of G(1)-arrested human breast cancer. Oncogene. 12:1996;2315-2324.
2. Banerjee M., Wood B., Lin F., Crump L. Tissue Culture Association Manual. 1976;TCA, Gaithersberg.
3. Bartkova J., Lukas J., Muller H., Lutzhoft D., Strauss M., Bartek J. Cyclin d1 protein expression and function in human breast cancer. Int. J. Cancer. 57:1994;353-361.
4. Cunha G., Young P., Hom Y., Coole P., Taylor J., Lubahn D. Elucidation of a role for stromal steroid hormone receptors in mammary gland growth and development using tissue recombination experiments. J. Mamm. Gland Biol. Neoplasia. 2:1997;393-402.
5. Daniel C., Silberstein G., Strickland P. Direct action of 17-β-estradiol on mammary ducts analysed by sustained release implants and steroid autoradiography. Cancer Res. 47:1987;6052-6057.
6. DeOme K., Faulkin L. J., Bern H., Blair P. Development of mammary tumors from hyperplastic alveolar nodules transplanted into gland-free mammary fat pads of female C3H mice. Cancer Res. 19:1959;515-520.
7. Edwards P., Abram C., Bradbury J. Genetic manipulation of mammary epithelium by transplantation. J. Mamm. Gland Biol. Neoplasia. 1:1996;75-90.
8. Edwards P., Hiby S., Papkoff J., Bradbury J. Hyperplasia of mouse mammary epithelium induced by expression of the wnt-1 (int-1) oncogene in reconstituted mammary gland. Oncogene. 7:1992;2041-2051.
9. Fantl V., Stamp G., Andrews A., Rosewell I., Dickson C. Mice lacking cyclin D1 are small and show defects in eye and mammary-gland development. Genes Dev. 9:1995;2364-2372.
10. Gillett C., Fantl V., Smith R., Fisher C., Bartek J., Dickson C., Barnes D., Peters G. Amplification and overexpression of cyclin-D1 in breast cancer detected by immunohistochemical staining. Cancer Res. 54:1994;1812-1817.
11. Ginsburg, Vonderhaar B. Prolactin synthesis and secretion by human cancer cells. Cancer Res. 55:1995;2591-2595.
12. Gouilleux F., Wakao H., Mundt M., Groner B. Prolactin induces phosphorylation of Tyr694 of stat (MGF), a prerequisite for DNA binding and induction of transcription. EMBO J. 13:1994;4361-4369.
13. Gubbins E., Maurer R., Lagrimini M., Erwin C., Donelson J. Structure of the rat prolactin gene. J. Biol. Chem. 255:1980;8655-8662.
14. Hall M., Peters G. Genetic alterations of cyclins, cyclin-dependent kinases, and cdk inhibitors in human cancer. Adv. Cancer Res. 68:1996;67-108.
15. Haslam S. Acquisition of estrogen-dependent progesterone receptors by normal mouse mammary gland. Ontogeny of mammary progesterone receptors. J. Steroid Biochem. 31:1988;9-13.
16. Haslam S., Shyamala G. Relative distribution of estrogen and progesterone receptors among the epithelial, adipose and connective tissue components of the normal mammary gland. Endocrinology. 108:1981;825-830.
17. Korach K., Couse J., Curtis S., Washburn T., Lindzey J., Kimbro K., Eddy E., Migliaccio S., Snedeker S., Lubahn D., Schomberg D., Smith E. Estrogen receptor gene disruption: Molecular characterization and experimental and clinical phenotypes. Rec. Prog. Horm. Res. 51:1996;159-188.
18. Li S., Rosen J. Nuclear factor 1 and mammary gland factor (STAT5) play a critical role in regulating rat whey acidic protein gene expression in transgenic mice. Mol. Cell. Biol. 15:1994;2063-2070.
19. Liu X., Robinson G., Gouilleux F., Groner B., Hennighausen L. Cloning and expression of stat5 and an additional homologue (stat5b) involved in prolactin signal transduction in mouse mammary tissue. Proc. Natl. Acad. Sci. USA. 92:1995;8831-8835.
20. Liu X., Robinson G., Hennighausen L. Activation of Stat5a and stat5b by tyrosine phosphorylation is tightly linked to mammary gland differentiation. Mol. Endocrinol. 10:1996;1496-1506.
21. Liu X., Robinson G., Wagner K., Garrett L., Wynshaw-Boris A., Hennighausen L. Stat5a is mandatory for adult mammary gland development and lactogenesis. Genes Dev. 11:1997;179-186.
22. Lukas J., Bartkova J., Bartek J. Convergence of mitogenic signaling cascades from diverse classes of receptors at the cyclin D-cyclin-dependent kinase-pRb-controlled G(1) checkpoint. Mol. Cell. Biol. 16:1996;6917-6925.
23. Lyndon J., DeMayo F., Funk C., Mani S., Hughes A., Montgomery C., Shyamala G., Conneely O., O'Malley B. Mice lacking progesterone receptor exhibit pleiotropic reproductive abnormalities. Genes Dev. 9:1995;2266-2278.
24. Musgrove E. A., Lee C. S. L., Buckley M. F., Sutherland R. L. Cyclin d1 induction in breast-cancer cells shortens G(1) and is sufficient for cells arrested in G(1) to complete the cell-cycle. Proc. Natl. Acad. Sci. USA. 91:1994;8022-8026.
25. Neuman E., Ladha M., Lin N., Upton T., Miller S., DiRenzo J., Pestell R., Hinds P., Dowdy S., Brown M., Ewen M. Cyclin D1 stimulation of estrogen receptor transcriptional activity independent of cdk4. Mol. Cell. Biol. 17:1997;5338-5347.
26. Ormandy C., Camus A., Barra J., Damotte D., Lucas B., Buteau H., Edery M., Brousse N., Babinet C., Binart N., Kelly P. Null mutation of the prolactin receptor gene produces multiple reproductive defects in the mouse. Genes Dev. 11:1997;167-178.
27. Quelle D., Ashmun R., Shurtleff S., Kato J., Barsagi D., Roussel M., Sherr C. Overexpression of mouse D-type cyclins accelerates G(1) phase in rodent fibroblasts. Genes Dev. 7:1993;1559-1571.
28. Resnitzky D., Reed S. I. Different roles for cyclin-d1 and cyclin-e in regulation of the G(1)-to-S transition. Mol. Cell. Biol. 15:1995;3463-3469.
29. Robinson G., Johnson P., Henninghausen L., Sterneck E. The C/EBPβ transcription factor regulates epithelial cell proliferation and differentiation in the mammary gland. Genes Dev. 12:1998;1907-1916.
30. Robinson G., McKnight R., Smith G., Hennighausen L. Mammary epithelial cells undergo secretory differentiation in cycling virgins but require pregnancy for the establishment of terminal differentiation. Development. 121:1995;2079-2090.
31. Seagroves T., Krnacik S., Raught B., Gay J., Burgess-Beusse B., Darlington G., Rosen J. C/EPBβ, but not C/EBPα, is essential for ductal morphogenesis, lobuloalveolar proliferation, and functional differentiation in the mammary gland. Genes Dev. 12:1998;1917-1928.
32. Sherr C. Cancer cell cycles. Science. 274:1996;1672-1677.
33. Sherr C., Roberts J. Inhibitors of mammalian G1 cyclin-dependent kinases. Genes Dev. 9:1995;1149-1163.
34. Shyamala G., Yang X., Silberstein G., Barcellos-Hoff M., Dale E. Transgenic mice carrying an imbalance in the native ratio of A to B forms of progesterone receptor exhibit developmental abnormalities in mammary glands. Proc. Natl. Acad. Sci. USA. 95:1998;696-701.
35. Sicinski P., Donaher J. L., Parker S. B., Li T. S., Gardner H., Haslam S. Z., Bronson R. T., Elledge S. J., Weinberg R. A. Cyclin D1 provides a link between development and oncogenesis in the retina and breast. Cell. 82:1995;621-630.
36. Sicinski P., Weinberg R. A specific role for cyclin D1 in mammary gland development. J. Mamm. Gland Biol. Neoplasia. 2:1997;335-342.
37. Smith R., Peters G., Dickson C. Genomic organization of the mouse cyclin d1 gene (cyl-1). Genomics. 25:1995;85-92.
38. Steel J., Jeffery R., Longcroft J., Rogers L., Poulsom R. Comparison of isotopic and non-isotopic labelling for in situ hybridisation of various messenger RNA targets with cRNA probes. Eur. J. Histochem. 42:1998;143-150.
39. Taylor-Papadimitriou J., Wetzels R., Ramaekers F. Intermediate filament protein expression in normal and malignant human mammary epithelial cells. Dickson R. B., Lippman M. E. Genes, Oncogenes and Hormones: Advances in Cellular and Molecular Biology of Breast Cancer. 1991;357-378 Kluwer, Dordrecht.
40. Teglund S., McKay C., Schuetz E., van Deursen J., Stravopodis D., Wang D., Brown M., Bodner S., Grosveld G., Ihle J. Stat5a and Stat5b proteins have essential and nonessential, or redundant, roles in cytokine responses. Cell. 93:1998;841-850.
41. Vonderhaar B. Prolactin: Transport, function, and receptors in mammary gland development and differentiation. Neville M. C., Daniel C. W. The Mammary Gland. 1987;383-438 Plenum, New York.
42. Wakao H., Gouilleux F., Groner B. Mammary gland factor (MGF) is a novel member of the cytokine regulated transcription factor gene family and confers the prolactin response. EMBO J. 13:1994;2182-2191.
43. Weinberg R. The retinoblastoma protein and cell cycle control. Cell. 81:1995;323-330.
44. Zwijsen R., Wientjens E., Klopmaker R., van der Sman J., Bernards R., Michalides R. CDK-independent activation of estrogen receptor by cyclin D1. Cell. 88:1997;405-415.