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Volumn 21, Issue 2, 1999, Pages 275-282

Decreased intracellular iron availability suppresses epithelial cell surface plasmin generation: Transcriptional and post-transcriptional effects on u-PA and PAI-1 expression

Author keywords

[No Author keywords available]

Indexed keywords

CHELATING AGENT; DEFEROXAMINE; INTERLEUKIN 1; IRON; MESSENGER RNA; PLASMIN; PLASMINOGEN ACTIVATOR INHIBITOR 1; UROKINASE;

EID: 0033174283     PISSN: 10441549     EISSN: None     Source Type: Journal    
DOI: 10.1165/ajrcmb.21.2.3445     Document Type: Article
Times cited : (12)

References (39)
  • 2
    • 0027452550 scopus 로고
    • Regulating the fate of mRNA: The control of cellular iron metabolism
    • Klausner, R., T. Ronault, and J. Harford. 1993. Regulating the fate of mRNA: the control of cellular iron metabolism. Cell 72:19-28.
    • (1993) Cell , vol.72 , pp. 19-28
    • Klausner, R.1    Ronault, T.2    Harford, J.3
  • 3
    • 0029758487 scopus 로고    scopus 로고
    • Molecular control of vertebrate iron metabolism: mRNA based regulatory circuits operated by iron, nitric oxide, and oxidative stress
    • Hentze, M., and L. Kuhn. 1996. Molecular control of vertebrate iron metabolism: mRNA based regulatory circuits operated by iron, nitric oxide, and oxidative stress. Proc. Natl. Acad. Sci. USA 92:8175-8182.
    • (1996) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 8175-8182
    • Hentze, M.1    Kuhn, L.2
  • 4
    • 0028075773 scopus 로고
    • Aconitase is a sensitive and critical target of oxygen poisoning in cultured mammalian cells and in rat lungs
    • Gardner, P. R., D.-D. H. Nguyen, and C. W. White. 1994. Aconitase is a sensitive and critical target of oxygen poisoning in cultured mammalian cells and in rat lungs. Proc. Natl. Acad. Sci. USA 91:12248-12252.
    • (1994) Proc. Natl. Acad. Sci. USA , vol.91 , pp. 12248-12252
    • Gardner, P.R.1    Nguyen, D.-D.H.2    White, C.W.3
  • 6
    • 0030054203 scopus 로고    scopus 로고
    • Bleomycin-induced pulmonary fibrosis in transgenic mice that either lack or overexpress the murine plasminogen activator inhibitor-1 gene
    • Eitzman, D. T., R. D. McCoy, X. Zheng, W. P. Fay, T. Shen, D. Ginsburg, and R. H. Simon. 1996. Bleomycin-induced pulmonary fibrosis in transgenic mice that either lack or overexpress the murine plasminogen activator inhibitor-1 gene. J. Clin. Invest. 97:232-237.
    • (1996) J. Clin. Invest. , vol.97 , pp. 232-237
    • Eitzman, D.T.1    McCoy, R.D.2    Zheng, X.3    Fay, W.P.4    Shen, T.5    Ginsburg, D.6    Simon, R.H.7
  • 8
    • 0015992802 scopus 로고
    • The type 2 cell as progenitor of alveolar epithelial regeneration: A cytodynamic study in mice after exposure to oxygen
    • Adamson, I. Y. R., and D. H. Bowden. 1974. The type 2 cell as progenitor of alveolar epithelial regeneration: a cytodynamic study in mice after exposure to oxygen. Lab. Invest. 30:35-42.
    • (1974) Lab. Invest. , vol.30 , pp. 35-42
    • Adamson, I.Y.R.1    Bowden, D.H.2
  • 9
    • 0025318614 scopus 로고
    • Alveolar epithelial cell plasminogen activator characterization and regulation
    • Marshall, B. C., D. S. Sageser, N. V. Rao, M. Emi, and J. R. Hoidal. 1990. Alveolar epithelial cell plasminogen activator characterization and regulation. J. Biol. Chem. 265:8198-8204.
    • (1990) J. Biol. Chem. , vol.265 , pp. 8198-8204
    • Marshall, B.C.1    Sageser, D.S.2    Rao, N.V.3    Emi, M.4    Hoidal, J.R.5
  • 10
    • 0026623560 scopus 로고
    • Fibrin degradation by rat pulmonary alveolar epithelial cells
    • Simon, R. H., T. J. Gross, J. A. Edwards, and R. G. Sitrin. 1992. Fibrin degradation by rat pulmonary alveolar epithelial cells. Am. J. physiol. 262: L482-L488.
    • (1992) Am. J. Physiol. , vol.262
    • Simon, R.H.1    Gross, T.J.2    Edwards, J.A.3    Sitrin, R.G.4
  • 11
    • 0025911199 scopus 로고
    • Rat alveolar epithelial cells concomitantly express plasminogen activator inhibitor-1 and urokinase
    • Gross, T. J., R. H. Simon, C. J. Kelly, and R. G. Sitrin. 1991. Rat alveolar epithelial cells concomitantly express plasminogen activator inhibitor-1 and urokinase. Am. J. Physiol. 260:L286-L295.
    • (1991) Am. J. Physiol. , vol.260
    • Gross, T.J.1    Simon, R.H.2    Kelly, C.J.3    Sitrin, R.G.4
  • 12
    • 0026687630 scopus 로고
    • Pulmonary epitheilal cell urokinase-type plasminogen activator: Induction by interleukin-1 beta and tumor necrosis factor-alpha
    • Marshall, B. C., Q.-P. Xu, N. V. Rao, B. R. Brown, and J. R. Hoidal. 1992. Pulmonary epitheilal cell urokinase-type plasminogen activator: induction by interleukin-1 beta and tumor necrosis factor-alpha. J. Biol. Chem. 267: 11462-11469.
    • (1992) J. Biol. Chem. , vol.267 , pp. 11462-11469
    • Marshall, B.C.1    Xu, Q.-P.2    Rao, N.V.3    Brown, B.R.4    Hoidal, J.R.5
  • 14
    • 0025344815 scopus 로고
    • Pulmonary syndrome in patients with thalassemia major receiving intravenous deferoxamine infusions
    • Freedman, M., D. Grisaru, N. Olivieri, I. MacLusky, and P. Thorner. 1990. Pulmonary syndrome in patients with thalassemia major receiving intravenous deferoxamine infusions. Am. J. Dis. Child. 144:565-569.
    • (1990) Am. J. Dis. Child. , vol.144 , pp. 565-569
    • Freedman, M.1    Grisaru, D.2    Olivieri, N.3    MacLusky, I.4    Thorner, P.5
  • 15
    • 0026571807 scopus 로고
    • Pulmonary toxic effects of continuous desferrioxamine administration in acute iron poisoning
    • Tenenhein, M., S. Kowalski, A. Sienko, D. Bowden, and I. Adamson. 1992. Pulmonary toxic effects of continuous desferrioxamine administration in acute iron poisoning. Lancet 339:699-701.
    • (1992) Lancet , vol.339 , pp. 699-701
    • Tenenhein, M.1    Kowalski, S.2    Sienko, A.3    Bowden, D.4    Adamson, I.5
  • 17
    • 0024121621 scopus 로고
    • Cytoplasmic protein binds in vitro to a highly conserved sequence in the 5′ untranslated region of ferritin heavy and light-subunit mRNAs
    • Leibold, E. A., and H. N. Munro. 1988. Cytoplasmic protein binds in vitro to a highly conserved sequence in the 5′ untranslated region of ferritin heavy and light-subunit mRNAs. Proc Natl. Acad. Sci. USA 85:2171-2175.
    • (1988) Proc Natl. Acad. Sci. USA , vol.85 , pp. 2171-2175
    • Leibold, E.A.1    Munro, H.N.2
  • 18
    • 0023664507 scopus 로고
    • Characterization and evolution of the expressed rat liver ferritin light subunit gene and its pseudogene family: Conservation of sequences within noncoding regions of ferritin genes
    • Leibold, E. A., and H. N. Munro. 1987. Characterization and evolution of the expressed rat liver ferritin light subunit gene and its pseudogene family: conservation of sequences within noncoding regions of ferritin genes. J. Biol. Chem. 262:7335-7341.
    • (1987) J. Biol. Chem. , vol.262 , pp. 7335-7341
    • Leibold, E.A.1    Munro, H.N.2
  • 19
    • 0000657412 scopus 로고
    • Preparation and analysis of RNA
    • F. B. Ausubel, R. Kingston, D. Moore, J. G. Seidman, J. A. Smith, and K. Struhl, editors. John Wiley and Sons, New York
    • Greenberg, M., and T. Bender. 1993. Preparation and analysis of RNA. In Current Protocols in Molecular Biology. F. B. Ausubel, R. Kingston, D. Moore, J. G. Seidman, J. A. Smith, and K. Struhl, editors. John Wiley and Sons, New York. 4.0.1-4.10.9.
    • (1993) Current Protocols in Molecular Biology , pp. 401-4109
    • Greenberg, M.1    Bender, T.2
  • 21
    • 0023884191 scopus 로고
    • Induction of ferritin subunit synthesis by iron is regulated at both the transcriptional and translational levels
    • White, K., and H. Munro. 1988. Induction of ferritin subunit synthesis by iron is regulated at both the transcriptional and translational levels. J. Biol. Chem. 263:8938-8942.
    • (1988) J. Biol. Chem. , vol.263 , pp. 8938-8942
    • White, K.1    Munro, H.2
  • 22
    • 0027992943 scopus 로고
    • Regulation of protein kinase C (PKC) expression by iron: Effect of different iron compounds on PKC-beta and PKC-alpha gene expression and role of the 5'-flanking region of the PKC-beta gene in the response to ferric transferrin
    • Alcantara, O., L. Obeid, and Y. Hannun. 1994. Regulation of protein kinase C (PKC) expression by iron: effect of different iron compounds on PKC-beta and PKC-alpha gene expression and role of the 5'-flanking region of the PKC-beta gene in the response to ferric transferrin. Blood 84:3510-3517.
    • (1994) Blood , vol.84 , pp. 3510-3517
    • Alcantara, O.1    Obeid, L.2    Hannun, Y.3
  • 23
    • 0028323380 scopus 로고
    • Transcriptional regulation of the tartrate-resistant acid phosphatase (TRAP) gene by iron
    • Alcantara, O., S. Reddy, G. Roodman, and D. Boldt. 1994. Transcriptional regulation of the tartrate-resistant acid phosphatase (TRAP) gene by iron. Biochem. J. 298:421-425.
    • (1994) Biochem. J. , vol.298 , pp. 421-425
    • Alcantara, O.1    Reddy, S.2    Roodman, G.3    Boldt, D.4
  • 24
    • 0026762333 scopus 로고
    • Post-transcriptional regulation of expression of plasminogen activator inhibitor type 1 mRNA by insulin and insulin-like growth factor
    • Fattal, P. G., D. J. Schneider, B. F. Sobel, and J. J. Billadello. 1992. Post-transcriptional regulation of expression of plasminogen activator inhibitor type 1 mRNA by insulin and insulin-like growth factor. J. Biol. Chem. 267: 12412-12415.
    • (1992) J. Biol. Chem. , vol.267 , pp. 12412-12415
    • Fattal, P.G.1    Schneider, D.J.2    Sobel, B.F.3    Billadello, J.J.4
  • 25
    • 0026000221 scopus 로고
    • Differential induction of two plasminogen activator inhibitor 1 mRNA species by phorbol ester in human hepatoma cells
    • Bosma, P. J., and T. Kooistra. 1991. Differential induction of two plasminogen activator inhibitor 1 mRNA species by phorbol ester in human hepatoma cells. J. Biol. Chem. 266:17845-17849.
    • (1991) J. Biol. Chem. , vol.266 , pp. 17845-17849
    • Bosma, P.J.1    Kooistra, T.2
  • 26
    • 0028266818 scopus 로고
    • Evidence that the pathway of transferrin receptor mRNA degradation involves an endonucleolytic cleavage within the 3′ UTR and does not involve poly (A) tail shortening
    • Binder, R., J. A. Horowitz, J. P. Basilion, D. M. Koeller, R. D. Klausner, and J. B. Harford. 1994. Evidence that the pathway of transferrin receptor mRNA degradation involves an endonucleolytic cleavage within the 3′ UTR and does not involve poly (A) tail shortening. EMBO J. 13:1969-1980.
    • (1994) EMBO J. , vol.13 , pp. 1969-1980
    • Binder, R.1    Horowitz, J.A.2    Basilion, J.P.3    Koeller, D.M.4    Klausner, R.D.5    Harford, J.B.6
  • 27
    • 0027136260 scopus 로고
    • Desferrioxamine induces erythropoietin gene expression and hypoxia-inducible factor 1 DNA binding activity: Implications for model of hypoxia signal transduction
    • Wang, G. L., and G. L. Semenza. 1993. Desferrioxamine induces erythropoietin gene expression and hypoxia-inducible factor 1 DNA binding activity: implications for model of hypoxia signal transduction. Blood 82: 3610-3615.
    • (1993) Blood , vol.82 , pp. 3610-3615
    • Wang, G.L.1    Semenza, G.L.2
  • 28
    • 0028095127 scopus 로고
    • Similarities between the oxygen-sensing mechanisms regulating the expression of vascular endothelial growth factor and erythropoietin
    • Goldberg, M. A., and T. J. Schneider. 1994. Similarities between the oxygen-sensing mechanisms regulating the expression of vascular endothelial growth factor and erythropoietin. J. Biol. Chem. 296:4355-4359.
    • (1994) J. Biol. Chem. , vol.296 , pp. 4355-4359
    • Goldberg, M.A.1    Schneider, T.J.2
  • 29
    • 0028843411 scopus 로고
    • Regulation of angiogenic growth factor expression by hypoxia, transition metals and chelating agents
    • Gleadle, J. M., B. L. Ebert, J. D. Firth, and P. J. Ratcliffe. 1995. Regulation of angiogenic growth factor expression by hypoxia, transition metals and chelating agents. Am. J. Physiol. 268:C1362-C1368.
    • (1995) Am. J. Physiol. , vol.268
    • Gleadle, J.M.1    Ebert, B.L.2    Firth, J.D.3    Ratcliffe, P.J.4
  • 30
    • 0028068606 scopus 로고
    • Transcriptional regulation of genes encoding glycolytic enzymes by hypoxia-inducible factor 1
    • Semenza, G. L., P. H. Roth, H.-M. Fang, and G. L. Wang. 1994. Transcriptional regulation of genes encoding glycolytic enzymes by hypoxia-inducible factor 1. J. Biol. Chem. 269:23757-23763.
    • (1994) J. Biol. Chem. , vol.269 , pp. 23757-23763
    • Semenza, G.L.1    Roth, P.H.2    Fang, H.-M.3    Wang, G.L.4
  • 31
    • 0028805375 scopus 로고
    • Hypoxia and mitochondrial inhibitors regulate expression of glucose transportor-1 via distinct cis-acting sequences
    • Ebert, B. L., J. D. Firth, and P. J. Ratcliffe. 1995. Hypoxia and mitochondrial inhibitors regulate expression of glucose transportor-1 via distinct cis-acting sequences. J. Biol. Chem. 270:29083-29089.
    • (1995) J. Biol. Chem. , vol.270 , pp. 29083-29089
    • Ebert, B.L.1    Firth, J.D.2    Ratcliffe, P.J.3
  • 32
    • 0032079312 scopus 로고    scopus 로고
    • Hypoxia stimulates urokinase receptor through a heme-dependent pathway
    • Graham, C. H., T. E. Fitzpatrick, and K. R. McCrae. 1998. Hypoxia stimulates urokinase receptor through a heme-dependent pathway. Blood 91: 3300-3307.
    • (1998) Blood , vol.91 , pp. 3300-3307
    • Graham, C.H.1    Fitzpatrick, T.E.2    McCrae, K.R.3
  • 33
    • 0031866706 scopus 로고    scopus 로고
    • Iron metabolism in the lower respiratory tract
    • Mateos, F., J. H. Brock, and J. L. Perez-Arellano, 1998. Iron metabolism in the lower respiratory tract. Thorax 53:594-600.
    • (1998) Thorax , vol.53 , pp. 594-600
    • Mateos, F.1    Brock, J.H.2    Perez-Arellano, J.L.3
  • 34
    • 0028308829 scopus 로고
    • Transient iron overload with bleomycin detectable iron in the plasma of patients with adult respiratory distress syndrome
    • Gutteridge, J. M., G. J. Ouinlan, and T. W. Evans. 1994. Transient iron overload with bleomycin detectable iron in the plasma of patients with adult respiratory distress syndrome. Thorax 49:707-710.
    • (1994) Thorax , vol.49 , pp. 707-710
    • Gutteridge, J.M.1    Ouinlan, G.J.2    Evans, T.W.3
  • 35
    • 0027939627 scopus 로고
    • Interaction of transferrin saturated with iron with lung surfactant in respiratory failure
    • Hallman, M., A. Sarnesto, and K. Bry. 1994. Interaction of transferrin saturated with iron with lung surfactant in respiratory failure. J. Appl. Physiol. 77:757-766.
    • (1994) J. Appl. Physiol. , vol.77 , pp. 757-766
    • Hallman, M.1    Sarnesto, A.2    Bry, K.3
  • 36
    • 0025902388 scopus 로고
    • Lower respiratory tract iron burden is increased in association with cigarette smoking
    • Thompson, A. B., T. Bohlin, A. Heires, J. Linder, and S. I. Rennard. 1991. Lower respiratory tract iron burden is increased in association with cigarette smoking. J. Lab. Clin. Med. 117:493-499.
    • (1991) J. Lab. Clin. Med. , vol.117 , pp. 493-499
    • Thompson, A.B.1    Bohlin, T.2    Heires, A.3    Linder, J.4    Rennard, S.I.5
  • 37
    • 0019881197 scopus 로고
    • Formation of a thiobarbiturie acid-reactive substance from deoxyribose in the presence of iron salts
    • Halliwell, B., and J. M. C. Gutteridge. 1981. Formation of a thiobarbiturie acid-reactive substance from deoxyribose in the presence of iron salts. FEBS Lett. 128:347-351.
    • (1981) FEBS Lett. , vol.128 , pp. 347-351
    • Halliwell, B.1    Gutteridge, J.M.C.2
  • 39
    • 0022572359 scopus 로고
    • Hematin-derived anticoagutant: Generation in vitro and in vivo
    • Jones, R. I., 1986. Hematin-derived anticoagutant: generation in vitro and in vivo. J. Exp. Med. 163:724-739.
    • (1986) J. Exp. Med. , vol.163 , pp. 724-739
    • Jones, R.I.1


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