Pindolol and major affective disorders: A three-year follow-up study of 30,485 patients

Journal of Clinical Psychopharmacology

Volumn 19, Issue 4, 1999, Pages 297-302

  Räsänen, Pirkko ^a   Hakko, Helinä ^a   Txiihonen, Jari ^b  

^a UNIVERSITY OF OULU   (Finland)

^b UNIVERSITY OF EASTERN FINLAND   (Finland)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIDEPRESSANT AGENT; ATENOLOL; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; CITALOPRAM; FLUOXETINE; METOPROLOL; PINDOLOL; PROPRANOLOL; SEROTONIN RECEPTOR; SEROTONIN UPTAKE INHIBITOR;

ADOLESCENT; ADULT; AFFECTIVE NEUROSIS; ARTICLE; CARDIOVASCULAR DISEASE; CONTROLLED STUDY; DEPRESSION; DISABILITY; DRUG POTENTIATION; FEMALE; HUMAN; LONG TERM CARE; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; THERAPY RESISTANCE; COMPARATIVE STUDY; DRUG COMBINATION; FOLLOW UP; MAJOR DEPRESSION; TREATMENT OUTCOME;

ADRENERGIC BETA-ANTAGONISTS; ATENOLOL; DEPRESSIVE DISORDER, MAJOR; DISABILITY EVALUATION; DRUG THERAPY, COMBINATION; FOLLOW-UP STUDIES; HUMANS; LONG-TERM CARE; METOPROLOL; PINDOLOL; PROPRANOLOL; SEROTONIN UPTAKE INHIBITORS; TREATMENT OUTCOME;

EID: 0033174211     PISSN: 02710749     EISSN: None     Source Type: Journal    
DOI: 10.1097/00004714-199908000-00002     Document Type: Article

References (30)

1. Adell A, Artigas F. Differential effects of clomipramine given locally or systemically on extracellular 5-hydroxytryptamine in raphe nuclei and frontal cortex: an in vivo microdialysis study. Naunyn Schmiedebergs Arch Pharmacol 1991;343:237-44.
2. Bel N, Artigas F. Fluvoxamine preferentially increases extracellular 5-hydroxytryptamine in the raphe nuclei: an in vivo microdialysis study. Eur J Pharmacol 1992;229:101-3.
3. Invernizzi R, Belli S, Samanin R. Citalopram's ability to increase the extracellular concentration of serotonin in the dorsal raphe prevents the drug's effect in frontal cortex. Brain Res 1992; 584:322-1.
4. Celada P, Artigas F. Monoamine oxidase inhibitors increase preferentially extracellular 5-hydroxytryptamine in the midbrain raphe nuclei. A brain microdialysis study in the awake rat. Naunyn Schmiedebergs Arch Pharmacol 1993;347:583-90.
5. Bel N, Artigas F. Chronic treatment with fluvoxamine increases extracellular serotonin in frontal cortex but not in raphe nuclei. Synapse 1993;15:243-5.
6. Ferrer A, Artigas F. Effects of single and chronic treatment with tranylcypromine on extracellular serotonin in rat brain. Eur J Pharmacol 1994;263:227-34.
7. Kreiss DS, Lucki I. Effects of acute and repeated administration of antidepressant drugs on extracellular levels of 5-hydroxytryptamine measured in vivo. J Pharmacol Exp Ther 1995;274:866-76.
8. 1A antagonists. Trends Neurosci 1996;19:378-83.
9. 1A receptors. Eur J Pharmacol 1994;260:243-6.
10. Romero L, Celada P, Artigas F. Reduction of in vivo striatal 5-hydroxytryptamine release by 8-OH-DPAT after inactivation of Gi/G(o) proteins in dorsal raphe nucleus. Eur J Pharmacol 1994;265:103-6.
11. 1A receptors: in vivo microdialysis and electrophysiological studies in the rat brain. Neuropsychopharmacology 1996;15:349-60.
12. 1A receptor antagonist and an SSRI in vivo: effects on 5-HT cell firing and extracellular 5-HT. Br J Pharmacol 1995; 115:1064-70.
13. Artigas F, Pérez V, Alvarez E. Pindolol induces a rapid improvement of depressed patients treated with serotonin reuptake inhibitors. Arch Gen Psychiatry 1994;51:248-51.
14. Blier P, Bergeron R. Effectiveness of pindolol with selected antidepressant drugs in the treatment of major depression. J Clin Psychopharmacol 1995;15:217-22.
15. Pérez V, Gilaberte I, Faries D, Alvarez E, Artigas F. Randomised, double-blind, placebo-controlled trial of pindolol in combination with fluoxetine antidepressant treatment. Lancet 1997;349: 1594-7.
16. Maes M, Vadoolaeghe E, Desnyder R. Efficacy of treatment with trazodone in combination with pindolol or fluoxetine in major depression. J Affect Disord 1996;41:201-10.
17. Tome MB, Cloninger CR, Watson JP, Isaac MT. Serotonergic autoreceptor blockade in the reduction of antidepressant latency: personality variables and response to paroxetine and pindolol. J Affect Disord 1997;44:101-9.
18. Zanardi R, Artigas F, Franchini L, Sforzini L, Gasperini M, Smeraldi E, Perez J. How long should pindolol be associated with paroxetine to improve the antidepressant response? J Clin Psychopharmacol 1997;17:446-50.
19. Tome MB, Isaac MT, Harte R, Holland C. Paroxetine and pindolol: a randomized trial of serotonergic autoreceptor blockade in the reduction of antidepressant latency. Int Clin Psychopharmacol 1997;12:81-9.
20. Berman RM, Darnell AM, Miller HL, Anand A, Charney DS. Effect of pindolol in hastening response to fluoxetine in the treatment of major depression: a double-blind, placebo-controlled trial. Am J Psychiatry 1997;154:37-43.
21. Moreno FA, Gelenberg AJ, Bachar K, Delgado PL. Pindolol augmentation of treatment-resistant depressed patients. J Clin Psychiatry 1997;58:437-9.
22. Potter WZ. Adrenoceptors and serotonin receptor function: relevance to antidepressant mechanisms of action. J Clin Psychiatry 1996;57[suppl 4]:4-8.
23. Chaput Y, de Montigny C, Blier P. Presynaptic and postsynaptic modifications of the serotonin system by long-term administration of antidepressant treatments. An in vivo electrophysiologic study in the rat. Neuropsychopharmacology 1991;5:219-29.
24. 1A receptors. Br J Pharmacol 1993;108:669-77.
25. Blier P, de Montigny C. Current advances and trends in the treatment of depression. Trends Pharmacol Sci 1994;15:220-6.
26. Howland RH. Biochemical effects of antidepressant augmentation [letter]. Arch Gen Psychiatry 1995;52:156.
27. Statistics Finland. Statistical Yearbook of Finland, 1995. Helsinki, Finland: Statistics Finland, 1995.
28. Suomen lääketilasto 1995. Lääkelaitos ja kansaneläkelaitos (in Finnish). Helsinki, Finland, 1995.
29. Avorn J, Everitt DE, Weiss S. Increased antidepressant use in patients prescribed β-blockers. JAMA 1986;255:357-60.
30. Thiessen BQ, Wallace SM, Blackburn JL, Wilson TW, Bergman U. Increased prescribing of antidepressant subsequent to β-blocker therapy. Arch Intern Med 1990;150:2286-90.