The effects of secondary structure and O2 on the formation of direct strand breaks upon UV irradiation of 5-bromodeoxyuridine-containing oligonucleotides

Chemistry and Biology

Volumn 6, Issue 7, 1999, Pages 451-459

  Cook, Gary P ^a   Chen, Tongqian ^a   Koppisch, Andrew T ^a   Greenberg, Marc M ^a  

^a Department of Environmental and Radiological Health Sciences   (United States)

Author keywords

5 bromodeoxyuridine; DNA damage; Free radicals; Radiosensitization

Indexed keywords

BROXURIDINE; DNA AMPLIFICATION; DNA STRAND; DNA STRAND BREAKAGE; FREE RADICAL SCAVENGER; HYDROGEN; ISOTOPE LABELING; NUCLEIC ACID HYBRIDIZATION; OLIGONUCLEOTIDE; OXIDATION; OXYGEN; RADIOSENSITIZING AGENT; REACTION MECHANISM; ULTRAVIOLET IRRADIATION;

EID: 0033168214     PISSN: 10745521     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1074-5521(99)80063-5     Document Type: Article

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