Model studies indicate that copper phenanthroline induces direct strand breaks via β-elimination of the 2'-deoxyribonolactone intermediate observed in enediyne mediated DNA damage [2]

Journal of the American Chemical Society

Volumn 120, Issue 15, 1998, Pages 3815-3816

  Chen, T ^a   Greenberg, M M ^a  

^a State University   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

1,10 PHENANTHROLINE COPPER; ALKADIENE; DEOXYRIBOSE; DNA; LACTONE DERIVATIVE; RADICAL; ZINOSTATIN CHROMOPHORE;

CATALYSIS; CHEMICAL REACTION; DNA DAMAGE; DNA STRAND BREAKAGE; LETTER; MASS SPECTROMETRY; MOLECULAR MODEL; PROTON NUCLEAR MAGNETIC RESONANCE; REACTION ANALYSIS;

EID: 0032557199     PISSN: 00027863     EISSN: None     Source Type: Journal    
DOI: 10.1021/ja9800075     Document Type: Letter

References (0)