메뉴 건너뛰기




Volumn 7, Issue 3, 1999, Pages 159-167

Mechanism of acute inhalation toxicity of alkanes and aliphatic alcohols

Author keywords

Acute inhalation toxicity; Alcohols; Alkanes; Partition; Quantitative structure activity relationships; Volatile organic compounds

Indexed keywords

2 PROPANOL; ALCOHOL; ALCOHOL DERIVATIVE; ALKANE DERIVATIVE; BUTANE; BUTANOL; DECANE; DECANOL; HEPTANE; HEPTANOL; HEXANE; METHANOL; NONANOL; OCTANE; PENTANE; PROPANOL; VOLATILE ORGANIC COMPOUND;

EID: 0033166912     PISSN: 13826689     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1382-6689(99)00010-1     Document Type: Article
Times cited : (11)

References (25)
  • 1
    • 0000453306 scopus 로고
    • Volume fraction correlation for narcosis in aquatic organisms: The key role of partitioning
    • Abernethy S.G., Mackay D., McCarty L.S. Volume fraction correlation for narcosis in aquatic organisms: the key role of partitioning. Environ. Toxicol. Chem. 7:1988;469-481.
    • (1988) Environ. Toxicol. Chem. , vol.7 , pp. 469-481
    • Abernethy, S.G.1    Mackay, D.2    McCarty, L.S.3
  • 2
    • 0029658412 scopus 로고    scopus 로고
    • Frequency and occurrence of LD50 values for materials in the workplace
    • Agrawal M.R., Winder C. Frequency and occurrence of LD50 values for materials in the workplace. J. Appl. Toxicol. 16(5):1996;407-422.
    • (1996) J. Appl. Toxicol. , vol.16 , Issue.5 , pp. 407-422
    • Agrawal, M.R.1    Winder, C.2
  • 3
    • 0020971460 scopus 로고
    • Odor as a aid to chemical safety: Odor thresholds compared with threshold limit values and volatilities for 214 industrial chemicals in air and water dilution
    • Amoore J.E., Hautala E. Odor as a aid to chemical safety: odor thresholds compared with threshold limit values and volatilities for 214 industrial chemicals in air and water dilution. J. Appl. Toxicol. 3:1983;272-290.
    • (1983) J. Appl. Toxicol. , vol.3 , pp. 272-290
    • Amoore, J.E.1    Hautala, E.2
  • 5
    • 0031413080 scopus 로고    scopus 로고
    • A quantitative property-property relationship (QPPR) approach to estimate in vitro tissue-blood partition coefficients of organic chemicals in rats and humans
    • DeJongh J., Verhaar H.J.M., Hermens J.L.M. A quantitative property-property relationship (QPPR) approach to estimate in vitro tissue-blood partition coefficients of organic chemicals in rats and humans. Arch. Toxicol. 72:1997;17-25.
    • (1997) Arch. Toxicol. , vol.72 , pp. 17-25
    • DeJongh, J.1    Verhaar, H.J.M.2    Hermens, J.L.M.3
  • 6
    • 0031722692 scopus 로고    scopus 로고
    • Roles of kinetics in acute lethality of nonreactive volatile organic compounds (VOCs)
    • DeJongh J., Verhaar H.J.M., Hermens J.L.M. Roles of kinetics in acute lethality of nonreactive volatile organic compounds (VOCs). Toxicol. Sci. 45:1998;26-32.
    • (1998) Toxicol. Sci. , vol.45 , pp. 26-32
    • DeJongh, J.1    Verhaar, H.J.M.2    Hermens, J.L.M.3
  • 8
    • 0013815474 scopus 로고
    • Minimum alveolar anesthetic concentration: A standard of anesthetic potency
    • Eger, II E.I., Saidman L.J., Brandstater B. Minimum alveolar anesthetic concentration: a standard of anesthetic potency. Anesthesiology. 26:1965;756-763.
    • (1965) Anesthesiology , vol.26 , pp. 756-763
    • Eger1    II, E.I.2    Saidman, L.J.3    Brandstater, B.4
  • 9
    • 0029908253 scopus 로고    scopus 로고
    • Anesthetic and convulsant properties of aromatic compounds and cycloalkanes: Implications for mechanisms of narcosis
    • Fang Z., Sonner J., Laster M.J., Ionescu P., Kandel L., Koblin D.D., Eger, II E.I., Halsey M.J. Anesthetic and convulsant properties of aromatic compounds and cycloalkanes: implications for mechanisms of narcosis. Anesth. Analg. 83:1996;1097-1104.
    • (1996) Anesth. Analg. , vol.83 , pp. 1097-1104
    • Fang, Z.1    Sonner, J.2    Laster, M.J.3    Ionescu, P.4    Kandel, L.5    Koblin, D.D.6    Eger7    II, E.I.8    Halsey, M.J.9
  • 10
    • 0031003762 scopus 로고    scopus 로고
    • Anesthetic potencies of n-alkanols: Results of additivity and solubility studies suggest a mechanism of action similar to that for conventional inhaled anesthetics
    • Fang Z., Ionescu P., Chortkoff B.S., Kandel L., Sonner J., Laster M.J., Eger, II E.I. Anesthetic potencies of n-alkanols: results of additivity and solubility studies suggest a mechanism of action similar to that for conventional inhaled anesthetics. Anesth. Analg. 84:1997;1042-1048.
    • (1997) Anesth. Analg. , vol.84 , pp. 1042-1048
    • Fang, Z.1    Ionescu, P.2    Chortkoff, B.S.3    Kandel, L.4    Sonner, J.5    Laster, M.J.6    Eger7    II, E.I.8
  • 13
    • 0019517032 scopus 로고
    • Quantitative structure-activity relationships in fish toxicity studies
    • Konemann H. Quantitative structure-activity relationships in fish toxicity studies. Toxicology. 19:1981;209-221.
    • (1981) Toxicology , vol.19 , pp. 209-221
    • Konemann, H.1
  • 14
    • 0028043837 scopus 로고
    • Effect of n-alkane kinetics in rats on potency estimations and the Meyer-Overton hypothesis
    • Liu J., Laster M.J., Taheri S., Eger, II E.I., Chortkoff B., Halsey M.J. Effect of n-alkane kinetics in rats on potency estimations and the Meyer-Overton hypothesis. Anesth. Analg. 79:1994;1049-1055.
    • (1994) Anesth. Analg. , vol.79 , pp. 1049-1055
    • Liu, J.1    Laster, M.J.2    Taheri, S.3    Eger4    II, E.I.5    Chortkoff, B.6    Halsey, M.J.7
  • 15
    • 0001724417 scopus 로고
    • The relationship between aquatic toxicity QSARs and bioconcentration for some organic chemicals
    • McCarty L.S. The relationship between aquatic toxicity QSARs and bioconcentration for some organic chemicals. Environ. Toxicol. Chem. 5:1986;1071-1080.
    • (1986) Environ. Toxicol. Chem. , vol.5 , pp. 1071-1080
    • McCarty, L.S.1
  • 16
    • 0009591653 scopus 로고
    • M.A. Mehlman. Princeton, NJ: Princeton Scientific Publishing
    • Mehlman M.A. Benchmarks: Alternative Methods in Toxicology. 1989;Princeton Scientific Publishing, Princeton, NJ.
    • (1989) Benchmarks: Alternative Methods in Toxicology
  • 18
    • 0025981685 scopus 로고
    • Hypothermic effects of a homologous series of short-chain alcohols in rats
    • Mohler F.S., Gordon C.J. Hypothermic effects of a homologous series of short-chain alcohols in rats. J. Toxicol. Environ. Health. 32:1991;129-139.
    • (1991) J. Toxicol. Environ. Health , vol.32 , pp. 129-139
    • Mohler, F.S.1    Gordon, C.J.2
  • 23
    • 0015460446 scopus 로고
    • The membrane actions of anesthetics and tranquilizers
    • Seeman P. The membrane actions of anesthetics and tranquilizers. Pharmacol. Rev. 24:1972;583-655.
    • (1972) Pharmacol. Rev. , vol.24 , pp. 583-655
    • Seeman, P.1
  • 24
    • 0022272078 scopus 로고
    • QSAR analysis and data extrapolation among mammals in a series of aliphatic alcohols
    • Tichy M., Trcka V., Roth Z., Krivucova M. QSAR analysis and data extrapolation among mammals in a series of aliphatic alcohols. Environ. Health Perspect. 61:1985;321-328.
    • (1985) Environ. Health Perspect. , vol.61 , pp. 321-328
    • Tichy, M.1    Trcka, V.2    Roth, Z.3    Krivucova, M.4
  • 25
    • 0026763272 scopus 로고
    • Alternative acute inhalation toxicity testing by determination of the concentration-time-mortality relationship: Experimental comparison with standard LC50 testing
    • Zwart A., Arts J.H.E., Ten Berge W.F., Appelman L.M. Alternative acute inhalation toxicity testing by determination of the concentration-time-mortality relationship: experimental comparison with standard LC50 testing. Regul. Toxicol. Pharmacol. 15:1992;278-290.
    • (1992) Regul. Toxicol. Pharmacol. , vol.15 , pp. 278-290
    • Zwart, A.1    Arts, J.H.E.2    Ten Berge, W.F.3    Appelman, L.M.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.