A versatile approach to trans-1,3-disubstituted tetrahydro-β-carbolines using oxazinanes

Heterocycles

Volumn 51, Issue 7, 1999, Pages 1509-1512

  Singh, Kamajit ^a   Deb, Prasant K ^a  

^a GURU NANAK DEV UNIVERSITY   (India)

Author keywords

[No Author keywords available]

Indexed keywords

ALDEHYDE; ALKALOID; CARBONYL DERIVATIVE; OXAZINANE; TRYPTOLINE; TRYPTOPHAN; UNCLASSIFIED DRUG;

ARTICLE; CARBON NUCLEAR MAGNETIC RESONANCE; CATALYSIS; CHEMICAL REACTION; CRYSTALLIZATION; DIASTEREOISOMER; PROTON NUCLEAR MAGNETIC RESONANCE; SYNTHESIS; THERMODYNAMICS;

EID: 0033166743     PISSN: 03855414     EISSN: None     Source Type: Journal    
DOI: 10.3987/COM-99-8580     Document Type: Article

References (9)

1. E. D. Cox and J. M. Cook, Chem. Rev., 1995, 95, 1797 and references cited therein.
2. E. D. Cox, L. K. Hamaker, J. Li, P. Yu, K. M. Czerwinski, L. Deng, D. W. Bennett, J. M. Cook, W. H. Watson, and M. Krawiec, J. Org Chem., 1997, 62, 44 and references cited therein.
3. A. I. Meyers, A. Nabeya, H. W. Adickes, I. R. Politzer, G. R. Malone, A. C. Kovelesky, R. L. Nolen, and R. C. Portnoy, J. Org Chem., 1973, 38, 36.
4. K. Singh, J. Singh, and H. Singh, Tetrahedron, 1996, 52, 14273 and references cited therein.
5. L. Lazar, A. G. Lakatos, F. Fulop, G, Bernath, and F. G. Riddell, Tetrahedron, 1997, 53, 1081 and references cited therein.
6. Using our standard conditions of reflux at 80°C, the yields refer to that of isolated compounds.
7. P. D. Bailey, M. H. Moore, K. M. Morgan, D. I. Smith, and J. M. Vernon, Tetrahedron Letts., 1994, 35, 3587.
8. b-benzyl substituents yielded equilibrated mixtures of corresponding 3 and 4.
9. 3), 106.40, 110.73, 113.72, 118.11, 119.22, 121.45, 127.12, 127.93, 128.65, 128.84, 129.77, 131.44, 134.94, 136.50, 142.42, 158.76, 172.69 (CO). * characteristic signals