Interleukin-17 up-regulation of nitric oxide production in human osteoarthritis cartilage

Arthritis and Rheumatism

Volumn 40, Issue 6, 1997, Pages 1050-1053

  Attur, Mukundan G ^a   Patel, Rajesh N ^a   Abramson, Steven B ^a   Amin, Ashok R ^a  

^a NYU HOSPITAL FOR JOINT DISEASES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACEBUTOLOL; CYCLOHEXIMIDE; DITHIOCARBAMIC ACID; GRANULOCYTE COLONY STIMULATING FACTOR; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; NITRIC OXIDE; PYRROLIDINE DERIVATIVE;

ARTICLE; CARTILAGE MATRIX; CELL ADHESION; CELL PROLIFERATION; DRUG EFFECT; ENZYME ACTIVATION; HUMAN; HUMAN TISSUE; KNEE ARTHROPLASTY; OPEN READING FRAME; OSTEOARTHRITIS; PRIORITY JOURNAL; RECEPTOR UPREGULATION; T LYMPHOCYTE ACTIVATION;

AGED; CARTILAGE, ARTICULAR; CYTOKINES; HUMANS; INTERLEUKIN-17; INTERLEUKINS; KNEE JOINT; KNEE PROSTHESIS; MIDDLE AGED; NITRIC OXIDE; OSTEOARTHRITIS; UP-REGULATION;

EID: 0030917573     PISSN: 00043591     EISSN: None     Source Type: Journal    
DOI: 10.1002/art.1780400609     Document Type: Article

References (13)

1. Broxmeyer HE: Is interleukin 17, an inducible cytokine that stimulates production of other cytokines, merely a redundant player in a sea of other biomolecules? J Exp Med 183:2411-2415, 1996
2. Schmidt HHHW, Walter U: Nitric oxide at work. Cell 78:919-925, 1994
3. Amin AR, DiCesare P, Vyas P, Attur M, Tzeng E, Billiar TR, Stuchin SA, Abramson SB: The expression and regulation of nitric oxide synthase in human osteoarthritis-affected chondrocytes: evidence for upregulatcd neuronal nitric oxide synthase. J Exp Med 182:2091-2102, 1995
4. Sakurai H, Kohsaka H, Liu MF, Higashiyama H, Hirata Y, Kanno K, Saito I, Miyasaka N: Nitric oxide production and inducible nitric oxide synthase expression in inflammatory arthritides. J Clin Invest 96:2357-2363, 1995
5. Clancy RM, Amin AR, Abramson SB: The role of nitric oxide in inflammation. Submitted for publication
6. Amin AR, Attur M, Patel RN, Thakker CD, Marshall PJ, Rediske J, Stuchin SA, Patel IR, Abramson SB: Superinduction of cyclooxygenase-2 in human osteoarthritis-affected cartilage: influence of nitric oxide. J Clin Invest (in press)
7. Dower SK, Wignall JM, Schooley K, McMahan CJ, Jackson JL, Prickelt KS, Lupton S, Cosman D, Sims JE: Retention of ligand binding activity by the extracellular domain of the IL-1 receptor. J Immunol 142:4314-4320, 1989
8. Gilliam MB, Sherman MI', Griscavage JM, Ignarro LJ: A spectro-photometric assay for nitrate using NADPH oxidation by Aspergillus nitrate reductase. Anal Biochem 212:359-365, 1993
9. Fussiez F, Djossou O, Chomarat P, Flores-Romo L, Ait-Yahia S, Maat C, Pin JJ, Garrone P, Garcia E, Saeland S, Blanchard D, Gaillard C, Das Mahapatra B, Rouvier E, Golstein P, Banchereau J, Lebecque S: T cell interleukin-17 induces stromal cells to produce proinflammatory and hematopoietic cytokines. J Exp Med 183:2593-2603, 1996
10. Schlaak JF, Pfers I, zum Buschenfelde KHM, Marker HE: Different cytokine profiles in the synovial fluid of patients with osteoarthritis. rheumatoid arthritis and seronegative spondyloarthropathies. Clin Exp Rheumatol 14:155-162. 1996
11. Recklies AD, Golds EE: Induction of synthesis and release of interleukin-8 from human articular chondrocytes and cartilage explants. Arthritis Rheum 35:1510-1519, 1992
12. Venn G, Nietfeld JJ, Duits AJ, Brennan FM, Arner E, Covington M, Billingham MEJ, Hardingham TE: Elevated synovial fluid levels of interleukin-6 and tumor necrosis factor associated with early experimental canine osteoarthritis. Arthritis Rheum 36:819-826, 1993
13. Yao Z, Fanslow WC, Seldin MF, Rousseau AM, Painter SL, Comeau MR, Cohen JI, Spriggs MK: Herpesvirus saimiri encodes a new cytokine, IL-17, which binds to a novel cytokine receptor. Immunity 3:811-821, 1995