Preliminary investigation of resistance of plasmid DNA to neon ion beams using transformation into recipient Escherichia coll cells

International Journal of Molecular Medicine

Volumn 4, Issue 1, 1999, Pages 57-59

  Nishimura, Akira ^a   Imamura, Masahiro ^a   Akagi, Kiyoshi ^a   Kasahara Imamura, Mika ^a   Okamura, Akiharu ^a   Watanabe, Hiroshi ^a   Ohnishi, Takeo ^a   Harada, Kazuki ^b  

^a KANSAI MEDICAL UNIVERSITY   (Japan)

^b YAMAGUCHI UNIVERSITY   (Japan)

Author keywords

DNA repair; Neon ion beam; pKmKS; Plasmid; Survival; TIARA

Indexed keywords

NEON;

ARTICLE; BACTERIAL GENE; DNA DAMAGE; DNA REPAIR; ESCHERICHIA COLI; GENETIC TRANSFORMATION; GENETICS; PLASMID; RADIATION EXPOSURE; RADIATION RESPONSE;

DNA DAMAGE; DNA REPAIR; DOSE-RESPONSE RELATIONSHIP, RADIATION; ESCHERICHIA COLI; GENES, BACTERIAL; NEON; PLASMIDS; TRANSFORMATION, GENETIC;

EID: 0033162346     PISSN: 11073756     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (14)

1. Imamura M, Seki T, Kunieda K, Wakabayashi M, Nakatani S, Shiro T and Inoue K: Development of local necrosis and side-effects after hepatic injections of acetic acid solutions. Int Hepatol Commun 3: 213-216, 1995.
2. Tamai T, Scki T, Imamura M, Wakabayashi M, Nakagawa T, Nishimura A, Yamashiki N, Inoue K, Okamura A and Harada K: Development of new therapy by percutaneous low concentration alkali injection targeting hepatocellular carcinoma. Digestion 59 (Suppl. 3): 366, 1998.
3. Imamura M, Seki T, Kunieda K, Nakatani S, Inoue K, Nakano T and Harada K: Hydroxyapatite beads containing doxorubicin hydrochloride (DOX) and buthioninc sulfoximine (BSO); a new anticanccr drug design for local treatment with multiple druss. Oncol Rep 2: 33-36, 1995.
4. Imamura M, Seki T, Kunieda K, Wakabayashi M, Inoue K, Obiya Y and Harada K: Antitumor effect of doxorubicin hydrochloride (DOX) and buthionine sulfoximine (BSO)-hydroxyapatite (HAP) complex on transplanted tumors in vivo. Oncol Rep 2: 509-511, 1995.
5. Imamura M, Scki T, Kunieda K, Nakatani S, Tamai T, Inoue K, Imamura M, Nagata K, Tanaka Y, Obiya Y and Harada K: Potential applicability of clinical hyperthermia using a Thermotron-RF8 as assessed from thermal distribution in an agar phantom containing hydroxyapatite. Oncol Rep 3: 1017-1019, 1996.
6. Imamura M, Seki T, Kunieda K, Tamai T, Nishimura A, Inoue K and Harada K: Enhancement by hyperthermia of the iiz vivo antitumour effect of doxorubicin hydrochloride (DOX) and buthioninc sulfoximine (BSO)-hydroxyapatite (HAP) complex. Int J Oncol 10: 961-964, 1997.
7. Imamura M, Murata T, Akagi K, Tanaka Y, Imamura M, Inoue K, Mizuma N, Kobayashi Y, Watanabe H, Hachiya M, Akashi M, Furusawa Y, Yamanaka H, Takahashi S, Nakano T, Nagaoka S, Ohnishi T, Obiya Y and Harada K: Relationship between LET and RBE values for Escherichia coli determined using carbon ion beams from the TIARA cyclotron and HIMAC synchrotron. J Gen Appl Microbiol 43: 175-177, 1997.
8. Takimoto K: Mutational changes in DNA nuclcotide sequence induced by proton mutagenesis of E. coli. Proceedings of the Eighth Space Utilization Symposium (in Japanese) 8: 134-139, 1991.
9. Takimoto K, Yamamoto K, Sagara T and Ishizaki K: Spectrum of proton-induced mutasenesis of the Escherichia coli crp gene. Mutat Res 314: 1-9, 1994.
10. Harada K, Nakano T, Watanabc H, Kobayashi Y, Tanaka A and Kikuchi M: Method of mutation spectrum analysis on DNA irradiated with ion beams using shuttle vector plasmid pZ189. In: JAERI TIARA Annual Report 1993. Vol. 3. Advanced Radiation Technology Center, Japan Atomic Energy Research Institute, pp52-54, 1994.
11. Nakano T, Okaichi K, Harada K, Matsumoto H, Kimura R, Yamamoto K, Akasaka S and Ohnishi T: Mutations of a shuttle vector plasmid, pZ189, in Escherichia coli induced by boron neutron captured beam (BNCB) containing α-particles. Mutat Res 336: 153-159, 1995.
12. Harada K, Obiya Y, Nakano T, Kawashima M, Miki T, Kobayashi Y, Watanabe H, Okaichi K, Ohnishi T, Mukai C and Nagaoka S: Cancer risk in space due to radiation assessed by determining cell lethality and mutation frequencies of prokaryotes and a plasmid during the Second International Microgravity Laboratory (IML-2) Space Shuttle experiment. Oncol Rep 4: 691-695, 1997.
13. Takimoto K, Uchino K, Ishizaki K and Ikenaga M: Specificity of mutational DNA sequence changes induced by X-rays in the cloned Escherichia coli crp gene. Mutat Res 254: 199-206, 1991.
14. Takimoto K, Tachibana A, Ayaki H and Yamamoto K: Spectrum of spontaneous mutations in the cyclic AMP receptor protein gene on chromosomal DNA of Escherichia coli. J Radial Res 38: 27-36, 1997.