New anti-inflammatory steroids : [16α,17α-d] isoxazoline derivatives of prednisolone and 9α-fluoroprednisolone

Medicinal Chemistry Research

Volumn 6, Issue 1, 1996, Pages 52-60

  Khalil, Mounir A ^a,b   Maponya, Mamakiri F ^a   Ko, Dong Hoon ^a   You, Zhengqing ^a   Oriaku, Ebenezer T ^a   Lee, Henry Joung ^a  

^a FLORIDA A AND M UNIVERSITY   (United States)

^b Alexandria University Faculty of Pharmacy   (Egypt)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 0002104784     PISSN: 10542523     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (26)

1. Hench, P. S.; Kendall, E. C.; Slocumb, C. H.; Polley, H. F., Proceedings Of The Staff Meetings Of The Mayo Clinic, 1949, 24, 181-197.
2. Siegel S. C., J. Allergy Clin. Immunol.,1985, 76, 312-320.
3. Schleimer, R. P., Ann. Rev. Respir. Dis., 1990, 141,S59-69.
4. Lee, H. J.; Soliman, M. R. I., Science, 1982, 215, 989-991.
5. Lee, H. J.; Heiman, A. S.; Taraporewala, I. B., In New Developments in Anti-Rheumatic Therapy, vol. III; Rainsford, K. D., and Velo, G. P., Eds., MPT Press, Lancaster, 1989, pp 153-186.
6. Khalil, M. A.; Kwon, T.; Lee, H. J., Current Topics in Med. Chem., 1993, 1, 173-202
7. Druzgala, P.; Hochhaus, G.; Bodor, N., J.Steroid Biochem.Molec. Biol., 1991, 38, (2). 149-154.
8. Ueno, H.; Maruyama, A.; Miyake, M.; Nakao, E.; Nakao, K.; Umezi, K.; Nitta, I., J. Med. Chem., 1991, 34, 2468-2473.
9. Hochhaus, G.; Chen, L-S.; Ratka, A.; Drazgala, P.; Howes, J.; Bodor, N.; Derendorf, H., J. Pharm. Sci., 1992, 81, 1210-1215,
10. Nathansohn, G.; Pasqualucci, C. R.; Radaelli, P.; Schiatti, P.; Selva, D.; Winters, G., Steroids, 1969, 13, 365-
11. Green, M. J.; Tiberi, R. L.; Frairy, R.; Lutsky, B. N.; Berkenkoph, J.; Fernandez, X.; Monahan, M., J. Med. Chem., 1982, 25, 1492-1495.
12. Kwon, T.; Heiman, A. S.; Oriaku, E. T.; Yoon, K.; Lee, H. J., J. Med. Chem., 1995, 38, 1048-1051.
13. De Sarlo, F.; Guarna, A.; Brandi, A.; Goti, A.; Corezzi, S., Tetrahedron, 1985, 41, 5181-5185.
14. Brandi, A.; De Sarlo; F.; Guarna, A.; Speroni, G., Synthesis, 1982, 719.
15. You, Z.; Khalil, M.A.; Ko, D-H.; Lee, H.J., Tetrahedron Lett., 1995, 36, 3303-3306.
16. Mc.Lean, H. M.; Khalil, M. A.; Heiman, A. S.; Lee, H. J., J. Pharm. Sci., 1994, 83, 476-480
17. Taraporewala, I. B.; Kim, H. P.; Heiman, A. S.; Lee, H. J., Arzneim,-Forsch./Drug Research, 1989, 39, 21-25.
18. Heiman, A. S.; Taraporewala, I. B.; McLean, H. M.; Hong, D.; Lee, H. J., J. Pharm. Sci., 1990, 79, 617-621.
19. Gower, D. B., Steroid Hormones, 1979, Croom Helm Ltd. Publishers, Britain, pp 19-29.
20. Popper, T. L.; Wantick, A. S., "Medicinal Chemistry"; Scherrer, R. A.; Whitehouse, M. W. Eds., Academic Press; New York, 1974,13, p 245-294..
21. Phillips, G. H., In Mehanism of Topical Corticosteroid Activity , Wilson, L. and Marks, R., Eds., Livinstone, Edingburgh, U.K., 1976, pp. 1-18.
22. Elks, J., Br. J. Dermatol., 1976, 94, Suppl. 12, 2-13.
23. Wolff, M. E., In Glucocorticoid Hormone Action, Baxter, J. D. and Rousseau, G. G., Eds., Springer, Berlin, Germany, 1979, pp. 97-107.
24. Ponec, M.; Kempenaar, J.; Shroot, B.; Caron, J-C., J. Pharm. Sci., 1986,75, 973-975.
25. Tonneli, G.; Thibault, L.; Ringer, L., Endocrinology, 1965, 77, 625-634.
26. Kim, H. P.; Bird, J.; Heiman, A. S.; Hudson, G. F.; Taraporewala, I. B.; Lee, H. J., J. Med. Chem., 1987, 30, 2239-2244.