The effects of long-term administration of recombinant bovine somatotropin (Posilac) and synovex on performance, plasma hormone and amino acid concentration, and muscle and subcutaneous fat fatty acid composition in Holstein-Friesian bull calves

Journal of Animal Science

Volumn 77, Issue 6, 1999, Pages 1422-1430

  Holzer, Z ^a   Aharoni, Y ^a   Brosh, A ^a   Orlov, A ^a   Veenhuizen, J J ^b   Kasser, T R ^b  

^a VOLCANI CENTER   (Israel)

^b MONSANTO COMPANY   (United States)

Author keywords

Beef; Calves; Estrogens; Males; Somatotropin

Indexed keywords

ANIMALIA; BOVINAE; FRIESIA; GADUS MORHUA;

AMINO ACID; CHOLESTEROL; DRUG DERIVATIVE; ESTRADIOL; FATTY ACID; GROWTH HORMONE; PROGESTERONE;

ADIPOSE TISSUE; ANIMAL; ARTICLE; CATTLE; DRUG COMBINATION; DRUG EFFECT; DUOGYNON FORTE; GROWTH, DEVELOPMENT AND AGING; MALE; METABOLISM; MUSCLE DEVELOPMENT; SKELETAL MUSCLE;

ADIPOSE TISSUE; AMINO ACIDS; ANIMALS; CATTLE; CHOLESTEROL; DRUG COMBINATIONS; ESTRADIOL; FATTY ACIDS; GROWTH HORMONE; MALE; MUSCLE DEVELOPMENT; MUSCLE, SKELETAL; PROGESTERONE;

EID: 0033142092     PISSN: 00218812     EISSN: None     Source Type: Journal    
DOI: 10.2527/1999.7761422x     Document Type: Article

References (42)

1. Abell, L. L., B. B. Levi, B. B. Brodie, and F. E. Kendal. 1952. A simplified method for estimation of total cholesterol in serum and a demonstration of its specificity. Biol. Chem. 195:357-361.
2. Aharoni, Y., E. Nachtomi, P. Holstein, A. Brosh, Z. Holzer, and Z. Nitsan. 1995. Dietary effects on fat deposition and fatty acid profiles in muscle and fat depots of Friesian bull calves. J. Anim. Sci. 73:2712-2720.
3. AOAC. 1990. Official Methods of Analysis (15th Ed.). Association of Official Analytical Chemists, Arlington, VA.
4. Bauman, D. E. 1992. Bovine somatotropin: Review of an emerging animal technology. J. Dairy Sci. 75:3432-3451.
5. Boisclair, Y. R., K. B. Johnston, D. E. Bauman, B. A. Crooker, F. R. Dunshea, and A. W. Bell. 1997. Paradoxical increases of circulating nonesterified fatty acids in somatotropin treated cattle undergoing mild disturbances. Domest. Anim. Endocrinol. 14: 251-262.
6. Breier, B. H., B. W. Gallaher, and P. D. Gluckman. 1991. Radioimmunoassay for insulin-like growth factor-1: Solutions to some potential problems and pitfalls. J. Endocrinol. 128:347-357.
7. Breier, B. H., P. D. Gluckman, and J. J. Bass. 1988a. Influence of nutritional status and oestradiol-17B on plasma growth hormone, insulin-like growth factors I and II and the response to exogenous growth hormone in young steers. J. Endocrinol. 118: 243-250.
8. Breier, B. H., P. D. Gluckman, and J. J. Bass. 1988b. The somatotrophic axis in young steers: Influence of nutritional status on oestradiol 17B on hepatic high-and low-affinity somatotrophic binding sites. J. Endocrinol. 116:169-177.
9. Coulombe, J. J., and L. Favreau. 1963. A new simple semi-micromethod for colorimetric determination of urea. Clin. Chem. 9:102-108.
10. Crooker, B. A., M. A. McGuire, W. S. Cohick, M. Harkins, D. E. Bauman, and K. Sejrsen. 1990. Effect of dose of bovine somatotropin on nutrient utilization in growing dairy heifers. J. Nutr. 120:1256-1263.
11. Dalke, B. S., M. J. Garber, R. A. Roeder, T. R. Kasser, C. J. Comstock, N. A. Reeve, and G. T. Schelling. 1991. Dose-response of recombinant bovine somatotropin (rbST) on serum somatotropin and insulin-like growth factor-1 levels in steers. J. Anim. Sci. 69(Suppl. 1):299 (Abstr.).
12. Dalke, B. S., R. A. Roeder, T. R. Kasser, J. J. Veenhuizen, C. W. Hunt, D. D. Hinman, and G. T. Schelling. 1992. Dose-response effects of recombinant bovine somatotropin implants on feedlot performance in steers. J. Anim. Sci. 70:2130-2137.
13. Eisemann, J. H., A. C. Hammond, T. R. Rumsey, and D. E. Bauman. 1989. Nitrogen and protein metabolism and metabolites in plasma and urine of beef steers treated with somatotropin. J. Anim. Sci. 67:105-115.
14. Elsasser, T. H., S. M. Czerwinski, T. S. Rumsey, W. M. Moseley, Y. Ono, and M. B. Solomon. 1994. Effects of Synovex-S and recombinant bovine growth hormone (Somavubove) on growth responses of steers: III. Muscle protein responses. J. Anim. Sci. 72 (Suppl. 1):162 (Abstr.).
15. Elsasser, T. H., T. S. Rumsey, and A. C. Hammond. 1989. Influence of diet on basal and growth hormone-stimulated plasma concentrations of IGF-1 in beef cattle. J. Anim. Sci. 67:128-141.
16. Enright, W. J. 1989. Effects of administration of somatotropin on growth, feed efficiency and carcass composition of ruminants: A review. In: K. Sejrsen, M. Vestergaard, and A. Neimann-Sorensen (Ed.) Use of Somatotropin in Livestock Production. pp 132-156. Elsevier Applied Science, London.
17. Enright, W. J., J. P. Quirke, P. D. Gluckman, B. H. Breier, L. G. Kennedy, I. C. Hart, J. F. Roche, A. Coert, and P. Allen. 1990. Effects of long-term administration of pituitary-derived bovine growth hormone and estradiol on growth in steers. J. Anim. Sci. 68:2345-2356.
18. Field, R. A. 1971. Effect of castration on meat quality and quantity. J. Anim. Sci. 32:849-858.
19. Folch, J., M. Lees, and G. H. Sloane-Stanley. 1957. A simple method for the isolation and purification of total lipids from animal tissues. J. Biol. Chem. 226:497-509.
20. Ford, J. J., and K. E. Gregory. 1983. Effects of late castration and zeranol on feedlot performance and carcass characteristics of bovine males. J. Anim. Sci. 57:286-291.
21. Gluckman, P. D., P. L. Muller, S. L. Kaplan, A. M. Rudolph, and M. M. Grumbach. 1979. Hormone ontogeny in the ovine fetus. I. Circulating growth hormone in mid and late gestation. Endocrinology 104:162-168.
22. Hawkins, D. A., J. A. Carrroll, C. N. Kemper Green, T. H. Welsh, Jr., and D. W. Forrest. 1995. Effect of recombinant bovine somatotropin (Posilac®) on growth and reproductive traits in yearling beef bulls. J. Anim. Sci. 73(Suppl. 1):153 (Abstr.).
23. Houseknecht, K. L., D. E. Bauman, D. G. Fox, and D. F. Smith. 1992. Abomasal infusion of casein enhanced nitrogen retention in somatotropin-treated steers. J. Nutr. 122:1717-1725.
24. Kay, M., and R. Houseman. 1975. The influence of sex on meat production. In: D.J.A. Cole and R. A. Lawrie (Ed.) Meat. p 85. Butterworths, London.
25. Klindt, J., F. C. Buonomo, J. T. Yen, and C. A. Baile. 1995. Growth performance, carcass characteristics, and sensory attributes of boars administered porcine somatotropin by sustained-release implant for different lengths of time. J. Anim. Sci. 73: 3585-3595.
26. Lawes Agricultural Trust. 1995. Genstat 5, Release 3.2. Rothamsted Experimental Station, Harpenden, Hertfordshire, U.K..
27. Levy, D., Z. Holzer, and R. Volcani. 1968. The effect of age and live weight on feed conversion and yield of saleable meat of intact Israeli Friesian male calves. Anim. Prod. 10:325-330.
28. Lobley, G. E. 1992. Control of the metabolic fate of amino acids in ruminants: A review. J. Anim. Sci. 70:3264-3275.
29. Mattson, F. H., and S. M. Grundy. 1985. Comparison of effects of dietary saturated, monounsaturated, and polyunsaturated fatty acids on plasma lipids and lipoproteins in man. J. Lipid Res. 26: 195-202.
30. McLaughlin, C. L., H. B. Hedrick, J. J. Veenhuizen, R. F. Finn, R. L. Hintz, G. F. Hartnell, T. R. Kasser, and C. A. Baile. 1993. Comparison of performance, clinical chemistry, and carcass characteristics of finishing lambs treated with recombinant ovine or bovine somatotropins. J. Anim. Sci. 71:1453-1463.
31. Morris, C. A., A. H. Hirton, B. W. Hogg, J. M. Brown, and B. J. Mortimer. 1995. Meat composition in genetically selected and control cattle from a serial slaughter experiment. Meat Sci. 39: 427-435.
32. Moseley, W. M., J. B. Paulissen, M. C. Goodwin, G. R. Alaniz, and W. H. Claflin. 1992. Recombinant bovine somatotropin improves growth performance in finishing beef steers. J. Anim. Sci. 70:412-425.
33. Peters, J. P. 1986. Consequences of accelerated gain and growth hormone administration for lipid metabolism in growing beef steers. J. Nutr. 116:2490-2503.
34. Preston, R. L., S. J. Bartle, T. R. Kasser, J. W. Day, J. J. Veenhuizen, and C. A. Baile. 1995. Comparative effectiveness of somatotropin and anabolic steroids in feedlot steers. J. Anim. Sci. 73:1038-1047.
35. Rumsey, T. S., T. H. Elsasser, and S. Kahl. 1996. Roasted soybeans and an estrogenic growth promoter affect growth hormone status and performance of beef steers. J. Nutr. 126:2880-2887.
36. Rumsey, T. S., T. H. Elsasser, and S. Kahl. 1997. Roasted soybeans and an estrogenic growth promoter affects the thyroid status of beef steers. J. Nutr. 127:352-358.
37. Rumsey, T. S., T. H. Elsasser, S. Kahl, W. M. Moseley, and M. B. Solomon. 1996. Effects of Synovex-S® and recombinant bovine growth hormone (Somavubove®) on growth responses of steers: I. Performance and composition of gain. J. Anim. Sci. 74: 2917-2928.
38. Schwarz, F. J., D. Schams, R. Röpke, M. Kirchgessner, J. Kögel, and P. Matzke. 1993. Effects of somatotropin treatment on growth performance, carcass traits, and the endocrine system in finishing beef heifers. J. Anim. Sci. 71:2721-2731.
39. Sejrsen, K., J. Foldager, S. Klastrup, and D. E. Bauman. 1986. Effect and mode of action of exogenous growth hormone on body tissue growth in heifers. 37th Annu. Mtg. EAAP 1:467 (Abstr.).
40. Solomon, M. B., J. B. Long, and J. S. Eastridge. 1997. The Hydrodyne: A new process to improve beef tenderness. J. Anim. Sci. 75:1534-1537.
41. Somogyi, M. 1945. Determination of blood sugar. Biol. Chem. 160: 69-73.
42. Taylor, D. G., and J. G. Cornell. 1985. The effect of electrical stimulation and ageing on beef tenderness. Meat Sci. 12: 243-251.