Total synthesis and conformational studies of hapalosin, N-desmethylhapalosin and 8-Deoxyhapalosin

Bioorganic and Medicinal Chemistry

Volumn 7, Issue 5, 1999, Pages 737-747

  Wagner, Björn ^a   Gonzalez, Gabriel Islas ^a   Tran Hun Dau, Marie Elise ^a   Zhu, Jieping ^a  

^a CNRS   (France)

Author keywords

anti MDR; Hapalosin; Macrolactamization; Oxazolidine; Selective N methylation

Indexed keywords

8 DEOXYHAPALOSIN; DEPSIPEPTIDE; DOXORUBICIN; HAPALOSIN; N DESMETHYLHAPALOSIN; UNCLASSIFIED DRUG; VERAPAMIL;

ARTICLE; CHROMATOGRAPHY; CONFORMATION; CONTROLLED STUDY; DRUG SYNTHESIS; ERYTHROLEUKEMIA CELL; HUMAN; HUMAN CELL; MULTIDRUG RESISTANCE;

DEPSIPEPTIDES; DRUG RESISTANCE, MULTIPLE; HUMANS; INHIBITORY CONCENTRATION 50; K562 CELLS; KINETICS; LACTAMS; LACTONES; MACROLIDES; MAGNETIC RESONANCE SPECTROSCOPY; MODELS, CHEMICAL; MODELS, MOLECULAR; PROTEIN CONFORMATION; TUMOR CELLS, CULTURED;

EID: 0033136062     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0968-0896(98)00208-9     Document Type: Article

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