Effect of exercise on the immune response of young and old horses

American Journal of Veterinary Research

Volumn 60, Issue 5, 1999, Pages 643-647

  Horohov, David W ^a   Dimock, Abigail ^b   Guirnalda, Patrick ^b   Folsom, Robert W ^a   McKeever, Kenneth H ^b   Malinowski, Karyn ^b  

^a LOUISIANA STATE UNIVERSITY   (United States)

^b RUTGERS UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

HYDROCORTISONE; INFLUENZA VACCINE; INTERLEUKIN 2; LACTIC ACID DERIVATIVE;

AGING; ANALYSIS OF VARIANCE; ANIMAL; ANIMAL EXPERIMENT; ARTICLE; BLOOD; CELL CULTURE; DRUG EFFECT; FEMALE; HEART RATE; HORSE; IMMUNOLOGY; LYMPHOCYTE; LYMPHOCYTE ACTIVATION; LYMPHOKINE ACTIVATED KILLER CELL; PHYSIOLOGY;

AGING; ANALYSIS OF VARIANCE; ANIMALS; CELLS, CULTURED; FEMALE; HEART RATE; HORSES; HYDROCORTISONE; INFLUENZA VACCINES; INTERLEUKIN-2; KILLER CELLS, LYMPHOKINE-ACTIVATED; LACTATES; LYMPHOCYTE ACTIVATION; LYMPHOCYTES; PHYSICAL CONDITIONING, ANIMAL;

EID: 0033129604     PISSN: 00029645     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (36)

1. Keadle TL, Pourciau SS, Melrose PA, et al. Acute exercise stress modulates equine immune function. J Equine Vet Sci 1993;13: 226-231.
2. Hoffman-Goetz L, Pedersen, BK Exercise and the immune system: a model of the stress response? Immunol Today 1994;15: 382-387.
3. Caruso C, Candore G, Cigna D, et al. Cytokine production pathway in the elderly. Immunol Res 1996;15:84-90.
4. Hirokawa K. Reversing and restoring immune functions. Mech Aging Dev 1997;93:119-124.
5. Goto H, Yamamoto Y, Ohta C, et al. Antibody responses of Japanese horses to influenza viruses in the past few years. J Vet Med Sci 1993;55:33-37.
6. Shephard RJ, Shek PN. Exercise, aging and immune function. Int J Sports Med 1995;16:1-6.
7. Csermely P, Penzes I, Toth S. Chronic overcrowding decreases cytoplasmic free calcium levels in T lymphocytes of aged CBA/CA mice. Experientia 1995;51:976-979.
8. Kanno J, Wakikawa A, Utsuyama M, et al. Effect of restraint stress on immune system and experimental B16 melanoma metastasis in aged mice. Mech Aging Dev 1997;93:107-117.
9. Fiatarone MA, Morley JE, Bloom ET, et al. The effect of exercise on natural killer cell activity in young and old subjects. J Gerontol 1989;44:M37-M45.
10. Grazzi L, Salmaggi A, Dufour A, et al. Physical effort-induced changes in immune parameters. Int J Neurosci 1993;68: 133-140.
11. Rincon HG, Solomon GF, Benton D, et al. Exercise in frail elderly men decreases natural killer cell activity. Aging 1996;8:109-112.
12. Mazzeo RS. The influence of exercise and aging on immune function. Med Sci Sports Exerc 1994;26:586-592.
13. McKeever KH, Malinowski K. Exercise capacity in young and old mares. Am J Vet Res 1997;58:1-5.
14. Hormanski CE, Truax R, Pourciau SS, et al. Induction of lymphokine activated killer cells of equine origin: specificity for equine target cells. Vet Immunol Immunopathol 1992;32:25-36.
15. Hintz HF. Nutrition of the geriatric horse, in Proceedings. Cornell Nutr Conf 1995;195-197.
16. Fraser D. Patient assessment. Infection in the elderly. J Gerontol Nurs 1993;19:5-11.
17. Serra JA, Fernandez-Gutierrez B, Hernandez-Garcia C, et al. Early T-cell activation in elderly humans. Aging 1996;25:470-478.
18. Hsueh CM, Chen SF, Ghanta VK, et al. Involvement of cytokine gene expression in the age-dependent decline of NK cell response. Cell Jmmunol 1996;173:221-229.
19. Lipschitz DA. Nutrition, aging, and the immunohematopoietic system. Clin Geriatr Med 1987;3:319-328.
20. Ronnenberg AG, Gross KL, Hartman WJ, et al. Dietary arginine supplementation does not enhance lymphocyte proliferation or interleukin-2 production in young and aged rats. J Nutr 1991;121: 1270-1278.
21. DiSanto JP. Cytokines: shared receptors, distinct functions. Curr Biol 1997;7:R424-R426.
22. Cannon JG, Fiatarone MA, Meydani M, et al. Aging and dietary modulation of elastase and interleukin-1 beta secretion. Am J Physiol 1995;268:R208-R213.
23. Lesourd B. Protein undernutrition as the major cause of decreased immune function in the elderly: clinical and functional implications. Nutr Rev 1995;53:S86-S94.
24. Johnson MA, Fischer JG, Bowman BA, et al. Iron nutriture in elderly individuals. FASEB J 1994;8:609-621.
25. Lesourd BM, Meaume S. Cell mediated immunity changes in ageing, relative importance of cell subpopulation switches and of nutritional factors. Immunol Lett 1994;40:235-42.
26. Gelato MC. Aging and immune function: a possible role for growth hormone. Horm Res 1996;45:46-49.
27. Ralston SL. Digestive alterations in aged horses. J Equine Vet Sci 1989;9:203-205.
28. Malinowski K, Christensen RA, Knonpka A, et al. Feed intake, body weight, body condition score, musculation, and immunocompetence in aged mares given equine somatotropin. J Anim Sci 1997;75:755-760.
29. Shepard RJ, Shek PN. Impact of physical activity and sport on the immune system. Rev Environ Health 1996;11:133-147.
30. Derijk R, Sternberg EM. Corticosteroid action and neuroendocrine-immune interactions. Ann N Y Acad Sci 1994;746:33-41.
31. Vago T, Clerici M, Norbiato G. Glucocorticoids and the immune system in AIDS. Clin Endocrinol Metab 1994;8:789-802.
32. Wilckens RW, De Rijk R. Glucocorticoids and immune function: unknown dimensions and new frontiers. Immunol Today 1997;18:418-424.
33. Everitt JC, Meites J. Anti-aging effects of hormones. J Gerontol 1989;44:B1139-B1147.
34. Rothuizen J, Reul JM, van Sluijs FJ. Increased neuroendocrine reactivity and decreased brain mineralocorticoid receptor-binding capacity in aged dogs. Endocrinology 1993;132:161-168.
35. Sapolsky RM, Krey LC, McEwen BS. The neuroendocrinology of stress and aging; the glucocorticoid cascade hypothesis. Endocrinol Rev 1986;7:234-304.
36. Horohov DW, Keadle TL, Pourciau SS, et al. Mechanism of exercise-induced augmentation of lymphokine activated killer (LAK) cell activity in the horse. Vet Immunol Immunopathol 1996;53: 221-233.