Prolactin-Producing Pituitary Adenoma and Carcinoma with Neuronal Components - A Metaplastic Lesion

Pituitary

Volumn 1, Issue 3-4, 1999, Pages 197-206

  Scheithauer, B W ^a   Horvath, E ^b   Kovacs, K ^b   Lloyd, R V ^a   Stefaneanu, L ^b   Buchfelder, M ^c   Fahlbusch, R ^c   Von Werder, K ^d   Lyons, D F ^e  

^a MAYO CLINIC   (United States)

^b ST MICHAEL'S HOSPITAL   (Canada)

^c UNIVERSITY OF ERLANGEN NUREMBERG   (Germany)

^d Schlosspark Klinik   (Germany)

^e Drs Hospital   (United States)

Author keywords

Pituitary adenoma carcinoma metaplasia; Prolactin

Indexed keywords

DOPAMINE RECEPTOR; MESSENGER RNA; NERVE GROWTH FACTOR RECEPTOR; PROLACTIN; RNA;

ADENOMA; ADULT; ARTICLE; BIOSYNTHESIS; CARCINOMA; CASE REPORT; CELL DIFFERENTIATION; FEMALE; GENETICS; HUMAN; HYPOPHYSIS TUMOR; IN SITU HYBRIDIZATION; MALE; METABOLISM; METAPLASIA; METASTASIS; MIDDLE AGED; NERVE CELL; PATHOLOGY; PATHOPHYSIOLOGY;

ADENOMA; ADULT; CARCINOMA; CELL DIFFERENTIATION; FEMALE; HUMANS; IN SITU HYBRIDIZATION; MALE; METAPLASIA; MIDDLE AGED; NEOPLASM METASTASIS; NEURONS; PITUITARY NEOPLASMS; PROLACTIN; RECEPTOR, NERVE GROWTH FACTOR; RECEPTORS, DOPAMINE; RNA, MESSENGER; RNA, NEOPLASM;

EID: 0033122842     PISSN: 1386341X     EISSN: None     Source Type: Journal    
DOI: 10.1023/a:1009913303109     Document Type: Article

References (43)

1. Kiyono H. Die histopathologies der hypophyse. Virchows Arch Pathol Anat 1926;259:388-465.
2. Lach B, Rippstein P, Benoit BG, Staines W. Differentiating neuroblastoma of pituitary gland: neuroblastic transformation of epithelial adenoma cells. J Neurosurg 1996;85:953-960.
3. Towfighi J, Salam MM, McLendon RE, Powers S, Page RB. Ganglion cell-containing tumors of the pituitary gland. Arch Pathol Lab Med 1996;120:369-377.
4. Asa SL, Bilbao JM, Kovacs K, Linfoot JA. Hypothalamic neuronal hamartoma associated with pituitary growth hormone cell adenoma and acromegaly. Acta Neuropathol 1980; 52:231-234.
5. Fischer EG, Morris JH, Kettyle WM. Intrasellar gangliocytoma and sydromes of pituitary hypersecretion. J Neurosurg 1983;59:1071-1075.
6. Scheithauer BW, Kovacs K, Randall RV, Horvath E, Okazaki H, Laws ER Jr. Hypothalamic neuronal hamartoma and adenohypophysial neuronal choristoma: Their association with growth hormone adenoma of the pituitary gland. J Neuropathol Exp Neurol 1983;42:648-663.
7. Asa SL, Scheithauer BW, Bilbao JM, Horvath E, Ryan N, Kovacs K, Randall RV, Laws ER Jr, Singer S, Linfoot JA, Thorner MO, Vale W. A case for hypothalamic acromegaly: A clinicopathological study of six patients with hypothalamic gangliocytomas producing growth hormone-releasing factor. J Clin Endocrinol Metab 1984;58:796-803.
8. Bevan JS, Asa SL, Rossi ML, Esiri MM, Adams CBT, Burke CW. Intrasellar gangliocytoma containing gastrin and growth hormone-releasing hormone associated with a growth hormone-secreting pituitary adenoma. Clin Endocrinol 1989;30:213-224.
9. Kamel OW, Horoupian DS, Silverberg GD. Mixed gangliocytoma-adenoma: A distinct neuroendocrine tumor of the pituitary fossa. Hum Pathol 1989;20:1198-1203.
10. Li JY, Racadot O, Kujas M, Kouadri M, Peillon F, Racadot J. Immunocytochemistry of four mixed pituitary adenomas and intrasellar gangliocytomas associated with different clinical syndromes: Acromegaly, amenorrhea-galactorrhea, Cushing's disease and isolated tumoral syndrome. Acta Neuropathol 1989;77:320-328.
11. Slowik F, Fazekas I, Balint K, Gazso L, Pasztor E, Czirjak S, Lapis K. Intrasellar hamartoma associated with pituitary adenoma. Acta Neuropathol 1990;80:328-333.
12. Burchiel KJ, Shaw CM, Kelly W. A mixed functional microadenoma and ganglioneuroma of the pituitary fossa. J Neurosurg 1983;58:416-420.
13. Horvath E, Kovacs K, Scheithauer BW, Lloyd RV, Smyth HS. Pituitary adenoma with neuronal choristoma (PANCH): composite lesion or lineage infidelity? Ultrastruct Pathol 1994;18:565-574.
14. Puchner MJA, Ludecke DK, Valdueza JM, Saeger W, Willig RP, Stalla GK, Odink RJ. Cushing's disease in a child caused by a corticotropin-releasing hormone-secreting intrasellar gangliocytoma associated with an adrenocorticotropic hormone-secreting pituitary adenoma. Neurosurgery 1993;33: 920-925.
15. Saeger W, Puchner MJA, Ludecke DK. Combined sellar gangliocytoma and pituitary adenoma in acromegaly or Cushing's disease. A report of 3 cases. Virchows Arch 1994;425: 93-99.
16. Pernicone PJ, Scheithauer BW, Sebo TJ, Kovacs KT, Horvath E, Young WF Jr, Lloyd RV, Davis DH, Guthrie BL, Schoene WC. Pituitary carcinoma. A clinicopathologic study of 15 cases. Cancer 1997;79:804-812.
17. Kovacs K, Lloyd RV, Horvath E. Silent somatotroph adenomas of the human pituitary. A morphologic study of three cases including immunocytochemistry, electron microscopy, in vitro examination, and in situ hybridization. Am J Pathol 1989;134:345-353.
18. Kovacs K, Stefaneanu L, Horvath E, Lloyd RV, Lancranjan I, Buchfelder M, Fahlbusch R. Effect of dopamine agonist medication on prolactin-producing pituitary adenomas. A morphologic study including immunocytochemistry, electron microscopy, and in situ hybridization. Virchows Arch Pathol Anat 1991;418:439-446.
19. Stefaneanu L, Kovacs K, Horvath E, Lloyd RV. In situ hybridization study of pro-opiomelanocortin (POMC) gene expression in human pituitary corticotrophs and their adenomas. Virchows Arch Pathol Anat 1991;419:107-113.
20. Stefaneanu L, Kovacs K, Horvath E, Lloyd RV, Buchfelder M, Fahlbusch R, Smyth H. In situ hybridization study of estrogen receptor messenger ribonucleic acid in human adenohypophysial cells and pituitary adenomas. J Clin Endocrinol Metab 1994;78:83-88.
21. kip1 expression in nontumorous and neoplastic human pituitaries. Am J Pathol 1997;151:509-519.
22. Thorner MO, Perryman RL, Cronin MJ, et al. Somatotroph hyperplasia: Successful treatment of acromegaly by removal of pancreatic islet tumor secreting a growth hormone releasing factor. J Clin Invest 1982;70:965-977.
23. Sano T, Asa SL, Kovacs K. Growth hormone-releasing hormone-producing tumors: clinical, biochemical and morphological manifestations. Endocr Rev 1988;9:357-373.
24. Stefaneanu L, Kovacs K, Horvath E, Asa SL, Losinski NE, Billestrup N, Price J, Vale W Adenohypophysial changes in mice transgenic for human growth hormone-releasing factor: A histologic, immunocytochemical, and electron microscopic investigation. Endocrinology 1989;125:2710-2718.
25. Asa SL, Kovacs K, Stefaneanu L, Horvath E, Billestrup N, Gonzales-Manchon C, Vale W. Pituitary adenomas in mice transgenic for growth hormone-releasing hormone. Endocrinology 1992;131:2083-2089.
26. Thapar K, Kovacs K, Stefaneanu L, Scheithauer BW, Killinger DW, Lloyd RV, Smyth HS, Barr A, Thorner MO, Gaylinn B, Laws ER Jr. Overexpression of the growth hormone-re-leasing hormone gene in acromegaly associated pituitary tumors: An event associated with neoplastic progression and aggressive behavior. Am J Pathol 1997;151:769-784.
27. Dubois PM, El Amraoui A, Heretier AG. Development and differentiation of pituitary cells. Microsc Res Tech 1997;39: 98-113.
28. Franke WW, Grund C, Archatatter T. Co-expression of cytokines and neurofilament proteins in a permanent cell line: Cultured rat PC12 cells combine neuronal and epithelial features. J Cell Biol 1986;103:1933-1943.
29. Tamir H, Liu KP, Payette RF. Human medullary thyroid carcinoma: Characterization of the serotoninergic and neuronal properties of a neuroectodermally derived cell line. J Neurosci 1989;9:1199-1212.
30. Altman H, Wigander AL, Nilsson O. Presence of nerve growth factor like immunoreactivity in carcinoid tumour cells and induction of a neuronal phenotype in long term culture. Int J Cancer 1989;43:949-955.
31. Polak M, Scharfmann R, Seilheimer B, Eisenbarth G, Dressler D, Verma IM, Porter H. Nerve growth factor induces neuron-like differentiation of an insulin-secreting pancreatic beta cell line. Proc Natl Acad Sci USA 1993;90: 5781-5785.
32. McCann FV, Pettengill OS, Cole JJ, Russell JAG, Sorenson GD. Calcium spike electrogenesis and other electrical activity in continuously cultured small cell carcinoma of the lung. Science 1981;212:1155-1157.
33. Martinez-Gampos A, Dannies PS. A possible differentiation of anterior pituitary cells in collagen gels into neurons. Cell Tissue Res 1986;244:21-26.
34. Schechter J, Windle JJ, Stauber C, Mellon PL. Neural tissue within anterior pituitary tumors generated by oncogene expression in transgenic mice. Neuroendocrinology 1992;56: 300-311.
35. Missale C, Boroni F, Sigala S, Zamellano A, Toso RD, Balsori A, Spano P. Nerve growth factor directs differentiation of the bipotential cell line GH-3 into the mammotroph phenotype. Endocrinology 1994;135:290-298.
36. Missale C, Boroni E, Fraasine M, Cariso A, Spano P. Nerve growth factor promotes the differentiation of pituitary mammotroph cells in vitro. Endocrinology 1995;136:1205-1213.
37. Missale C, Boroni F, Losa M, Giovanelli M, Zanellato A, Dal Toso R, Spano P. Nerve growth factor suppresses the transforming phenotype of human prolactinomas. Proc Natl Acad Sci USA 1993;90:7961-7965.
38. Borelli E, Sawchenko PE, Evans RM. Pituitary hyperplasia induced by ectopic expression of nerve growth factor. Proc Natl Acad Sci USA 1992;89:2764-2768.
39. Maness LM, Kastin AJ, Weber JT, Banks WA, Beckman BS, Zadine JE. The neurotrophins and their receptors: Structure, function, and neuropathology. Neurosci Behav Rev 1994;18:1:143-159.
40. Missale C, Boroni F, Sigala S, Burian A, Fabris M, Lean A, Dol Tosu R, Sparo PF. Nerve growth factor in the anterior pituitary: Localization in mammotroph cells and cosecretion with prolactin by a dopamine-regulated mechanism. Proc Natl Acad Sci USA 1996;93:4240-4245.
41. Missale C, Losa M, Sigala S, Balsani A, Giovanelli M, Spano PF. Nerve growth factor controls proliferation and progression of human prolactinoma cell lines through an autocrine mechanism. Mol Endocrinol 1996;10:272-285.
42. Melmed S, Ho K, Klibanski A, Reichlin S, Thorner M. Recent advances in pathogenesis, diagnosis, and management of acromegaly. J Clin Endocrinol Metab 1995;80:3395-3402.
43. Cittren L. The regulation of growth hormone secretion. Endocr Metab Clin N Am 1996;25:541-571.