p53 induction in normal human skin in vitro following exposure to solar simulated UV and UV-B irradiation

Journal of Photochemistry and Photobiology B: Biology

Volumn 49, Issue 2-3, 1999, Pages 177-186

  Davenport, Victoria ^a   Morris, Jenny F ^a   Motazed, Reza ^a   Chu, Anthony C ^a  

^a HAMMERSMITH HOSPITAL   (United Kingdom)

Author keywords

Epidermal p53; Skin explant model; Solar simulated radiation; UV B

Indexed keywords

PROTEIN P53;

ARTICLE; CELL DAMAGE; CONTROLLED STUDY; ERYTHEMA; EXPLANT; GENE INDUCTION; HUMAN; HUMAN CELL; IMMUNOBLOTTING; IMMUNOHISTOCHEMISTRY; LIGHT DAMAGE; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; RADIATION DOSE; RADIATION INJURY; SKIN CELL; ULTRAVIOLET B RADIATION; ULTRAVIOLET IRRADIATION; ULTRAVIOLET RADIATION;

EID: 0033121159     PISSN: 10111344     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1011-1344(99)00053-6     Document Type: Article

References (32)

1. V. Davenport, J.F. Morris, A.C. Chu, Immunologie protection afforded by sunscreens in vitro, J. Invest Dermatol. 108 (1997) 859-863.
2. K.D. Cooper, P. Fox, G, Neisis, S.I. Katz, Effects of ultraviolet radiation on human epidermal cell alloantigen presentation: Initial depression of Langerhans' cell-dependent function is followed by the appearance of T6-Dr+ cells that enhance epidermal alloantigen presentation, J. Immunol. 134 (1985) 129-137.
3. D.P. Lane, L.V. Crawford, T antigen is bound to a host protein in SV-40 transformed cells, Nature 278 (1979) 261-263.
4. M. Isobe, B.S. Emanuel, D. Givoli, M. Oren, C.M. Croce, Localisation of gene for human p53 tumour antigen to band 17pl3, Nature 320 (1986) 84-85.
5. N.S. McNutt, C. Saenz-Santamaria, M. Volkenandt, Abnormalities of p53 protein expression in cutaneous disorders, Arch. Dermatol. 130 (1994) 225-232.
6. N.C. Reich, A.J. Levine, Growth regulation of a cellular tumour antigen p53 in non-transformed cells, Nature 308 (1984) 199-201.
7. N.L. Hubbert, S.A. Sedman, J.T. Schiller, Human papillomavirus type 16 E6 increases the degradation rate of p53 in human keratinocytes, J. Virol. 66 (1992) 6237-6241.
8. D.F. Spandau, Distinct conformations of p53 are observed at different stages of keratinocyte differentiation, Oncogene 9 (1994) 1861-1868.
9. S.J. Kuerbitz, B.S. Plunkett, W.V. Walsh, M.B. Kastan, Wild-type p53 is a cell cycle checkpoint determinant following irradiation, Proc. Natl. Acad. Sci. USA 89 (1992) 7491-7495.
10. D. Lin, M.T. Sheilds, S.J. Ullrich, E. Apella, W.E. Mercer, Growth arrest induced by wild type p53 protein blocks cells prior to or near the restriction point in late G1 phase, Proc. Natl. Acad. Sci. USA 89 (1992) 9210-9214.
11. W. Maltzman, I. Czyzyk, UV irradiation stimulates levels of p53 cellular tumour antigen in nontransformed mouse cells, Mol. Cell Biol. 4 (1984) 1689-1694.
12. E. Healy, N.J. Reynolds, M.D. Smith, C. Campbell, P.M. Farr, J.L. Rees, Dissociation of erythema and p53 protein expression in human skin following UVB irradiation, and induction of p53 protein and mRNA following application of skin irritants, J. Invest. Dermatol. 103 (1994) 493-499.
13. D.P. Lane, X. Lu, P.A. Hall, The role of p53 protein in the apoptotic response, Philos. Trans. R. Soc. Lond. B 345 (1994) 277-280.
14. X. Lu, D.P. Lane, Differential induction of transcriptionally active p53 following UV or ionising radiation: Defects in chromosome instability syndromes, Cell 75 (1993) 765-778.
15. W.G. An, M. Kanekal, M.C. Simon, M.V. Blagosklonny, L.M. Neckers, Stabilization of wild-type p53 by hypoxia-inducible factor, Nature 392 (1998) 405-408.
16. M.V. Blagosklonny, Loss of function and p53 protein stabilization. Oncogene 15 (1997) 1889-1893.
17. S.Y. Fuchs, V. Adler, M.R. Pincus, Z. Ronai, MEKK1/JNK signaling stabilizes and activates 53, Proc. Natl. Acad. Sci. USA 95 (1998) 10541-10546.
18. J. Kaur, A. Srivastava, R. Ralhan, P53-HSP70 complexes in oral dysplsia and cancer: Potential prognostic implications, Eur. J. Cancer B: Oral Oncol. 32B (1996) 45-49.
19. Y. Haupt, R. Maya, A. Kazaz, M. Oren, Mdm2 promotes the rapid degradation of p53, Nature 387 (1997) 296-299.
20. P.A. Hall, P.H. McKee, H. Du P. Menage, R. Dover, D.P. Lane, High levels of p53 protein in UV-irradiated normal human skin, Oncogene 8 (1993) 203-207.
21. C. Campbell, A.G. Quinn, B. Angus, P.M. Farr, J.L. Rees, Wavelength specific patterns of p53 induction in human skin following exposure to UV irradiation, Cancer Res. 53 (1993) 2697-2699.
22. Y. Urano, T. Asano, K. Yoshimoto, et al., Frequent p53 accumulation in the chronically sun-exposed epidermis and clonal expansion of p53 mutant cells in the epidermis adjacent to basal cell carcinoma, J. Invest. Dermatol. 104 (1995) 928-932.
23. P.A. Hall, D.P. Lane, P53 in tumour pathology: Can we trust immunohistochemistry?-revisited (editorial), J. Pathol. 172 (1994) 1-4.
24. H.A. Lambkin, C.M. Mothersill, P. Kelehan, Variations in immunohistochemical detection of p53 protein overexpression in cervical carcinomas with different antibodies and methods of detection, J. Pathol. 172 (1994) 13-18.
25. T.W. Jacobs, J.E. Prioleau, I.E. Stillman, S.J. Schnitt, Loss of tumour marker-immunostaining intensity on stored paraffin slides of breast cancer, J. Natl. Cancer Inst. 88 (1996) 1054-1059.
26. U. Henseleit, J. Zhang, R. Wanner, I. Haase, G. Kolde, T. Rosenbach, Role of p53 in UVB-induced apoptosis in human HaCaT keratinocytes, J. Invest. Dermatol. 109 (1997) 722-727.
27. A.A. El-Ghorr, M. Norval, Biological effects of narrow-band (311nm TLO1) UVB irradiation: A review, J. Photochem. Photobiol. B: Biol. 38 (1997) 99-106.
28. S.R. Shi, M.E. Key, K.L. Kalra, Antigen retrieval in formalin-fixed paraffin embedded tissues; an enhancement method for immunohistochemical staining based on microwave oven heating of tissue sections, J. Histochem. Cytochem. 39 (1991) 741-748.
29. G. Cattoretti, S. Pileri, S. Parravicini, M. Beckers, S. Poggi, C. Bifulco, G. Key, L. D'Amato, E. Sabattini, E. Feudale, F. Raynolds, J. Gerdes, F. Rilke, Antigen unmasking of formalin-fixed, paraffin embedded tissue sections, J. Pathol. 171 (1993) 83-98.
30. M. Lunjman, F. Zhang, Blockage of RNA polymerase as a possible trigger for UV light-induced apoptosis, Oncogene 13 (1996) 823-831.
31. D.E. Godar, A.D. Lucas, Spectral dependence of UV-induced immediate and delayed apoptosis: The role of membrane and DNA damage, Photochem. Photobiol. 62 (1995) 108-113.
32. M. Nakamura, T. Rikimaru, T. Yano, K.G. Moore, P.J. Pula, B.H. Schofield, A.M. Dannenberg Jr., Full-thickness human skin explants for testing the toxicity of topically applied chemicals, J. Invest. Dermatol. 95 (1990) 325-332.