Autoantibodies to T cell costimulatory molecules in systemic autoimmune diseases

Journal of Immunology

Volumn 162, Issue 7, 1999, Pages 4328-4335

  Matsui, Toshihiro ^a,b   Kurokawa, Manae ^a   Kobata, Tetsuji ^a,c   Oki, Shinji ^d   Azuma, Miyuki ^d   Tohma, Shigeto ^b   Inoue, Tetsufumi ^b   Yamamoto, Kazuhiko ^b   Nishioka, Kusuki ^a   Kato, Tomohiro ^a  

^a ST MARIANNA UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b UNIVERSITY OF TOKYO   (Japan)

^c JUNTENDO UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^d NATIONAL RESEARCH INSTITUTE FOR CHILD HEALTH AND DEVELOPMENT   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

AUTOANTIBODY; T LYMPHOCYTE ANTIBODY;

ADULT; AGED; ANTIGEN BINDING; ARTICLE; AUTOIMMUNE DISEASE; BEHCET DISEASE; FEMALE; HUMAN; IMMUNE RESPONSE; IMMUNOSTIMULATION; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; T LYMPHOCYTE; UVEITIS;

EID: 0033120579     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (52)

1. Osman, C., and A. J. G. Swaak. 1994. Lymphocytotoxic antibodies in SLE: a review of the literature. Clin. Rheum. 13:21.
2. Swaak, A. J. G. 1996. Lymphocytotoxic autoantibodies. In Autoantibodies. J. B. Peter and Y. Shoenfeld, eds. Elsevier Science, Amsterdam, p. 478.
3. Winfield, J. B., and T. Mimura. 1992. Pathogenetic significance of antilymphocyte autoantibodies in systemic lupus erythemalosus. Clin. Immunol. Immunopathol. 63:13.
4. Winfield, J. B., R. J. Winchester, and H. G. Kunkel. 1975. Association of coldreactive antilymphocyte antibodies with lymphopenia in systemic lupus erythematosus. Arthritis Rheum. 18:587.
5. Morimoto, C., A. D. Steinberg, N. L. Letvin, M. Hagan, T. Takeuchi, J. Daley, H. Levine, and S. F. Schlossman. 1987. A defect of immunoregulatory T cell subsets in systemic lupus crythematosus patients demonstrated with anti-2H4 antibody. J Clin. Invest. 79:762.
6. + cell populations in patients with systemic lupus erythematosus. Arthritis Rheum. 32:398.
7. Wernet, P., and H. G. Kunkel. 1973. Antibodies to specific surface antigen on T cells in human sera inhibiting mixed leukocyte culture reactions. J. Exp. Med. 138:1021.
8. Sakane, T., A. D. Steinberg, J. P. Reeves, and I. Green. 1979. Studies of immune functions of patients with systemic lupus erythematosus; T-cell subsets and antibodies to T-cell subsets. J. Clin. Invest. 64:1260.
9. Takeuchi, T., T. Abe, M. Kiyota, T. Toguchi, J. Koide, C. Morimoto, and C. Homma. 1982. In vitro immune response of SLE lymphocytes: the mechanism involved in B-cell activation. Scand. J. Immunol. 16:369.
10. Morimoto, C., and S. Schlossman, F. 1987. Antilymphocyte antibodies and systemic lupus erythemalosus. Arthritis Rheum. 30:225.
11. Mimura, T., P. Fernsten, W. Jarjour, and J. B. Winfield. 1990. Autoantibodies specific for different isoforms of CD45 in systemic lupus erythematosus. J. Exp. Med. 172:653.
12. Czyzyk, J., P. Fernsten, M. Shaw, and J. B. Winfield. 1996. Cell-type specificity of anti-CD45 autoantibodies in systemic lupus erythemalosus. Arthritis Rheum. 39:592.
13. 2-microglobulin lymphocytotoxic autoantibodies in systemic lupus erythematosus. J. Immunol. 122:614.
14. Propper, D. J., W. A. Lehney, S. J. Urbaniak, G. R. Catto, and A. M. Macleod. 1991. Lymphocytotoxins in sera from highly sensitized multiparous dialysis patients: antibody class, relationship with the HLA and with paternal antigens. Clin. Sci. 80:87.
15. Mueller, D. L., M. K. Jenkins, and R H. Schwartz. 1989. Clonal expansion versus clonal inactivation: a costimulatory signaling pathway determines the outcome of T cell antigen receptor occupancy. Annu. Rev. Immunol. 7:445.
16. Lenschhow, D. J., T. L. Walunas, and J. A. Bluestone. 1996. CD28/B7 system of T cell costimulation. Annu. Rev. Immunol. 14:233.
17. Gause, W. C., M. J. Halvorson, P. Lu, R. Greenwald, P. Linsley, J. F. Urban, and F. D. Finkelman. 1997. The function of costimulatory molecules and the development of IL-4-producing T cells. Immunol. Today. 18:115.
18. Linsley, P. S., J. L. Greene, P. Tan, J. Bradshaw, J. A. Ledbetter, C. Anasetti, and N. K. Damle. 1992. Coexpression and functional cooperation of CTLA-4 and CD28 on activated T lymphocytes. J. Exp. Med. 176:1595.
19. Walunas, T. L., D. J. Lenschow, C. Y. Bakker, P. S. Linsley, G. J. Freeman, J. M. Green, C. B. Thompson, and J. A. Bluestone. 1994. CTLA-4 can function as a negative regulator of T cell activation. Immunity 1:405.
20. Krummel, M. F., and J. P. Allison. 1995. CD28 and CTLA-4 have opposing effects on the response of T cells to stimulation. J. Exp. Med. 182:459.
21. Waterhouse, P., J. M. Penninger, E. Timms, A. Wakeham, A. Shahinian, K. P. Lee, C. B. Thompson, H. Griesser, and T. W. Mak. 1995. Lymphoproliferative disorders with early lethality in mice deficient in Ctla-4. Science 270:985.
22. Tivol, E. A., F. Borriello, A. N. Schweitzer, W. P. Lynch, J. A. Bluestone, and A. H. Sharpe. 1995. Loss of CTLA-4 leads to massive lymphoproliferation and fatal multiorgan tissue destruction, revealing a critical negative regulatory role of CTLA-4. Immunity 3:541.
23. Karandikar, N. L., C. L. Vanderlugt, T. L. Walunas, S. D. Miller, and J. A. Bluestone. 1996. CTLA-4: a negative regulator of autoimmune disease. J. Exp. Med. 184:783.
24. Perrin, P. J., J. H. Maldonado, T. A. Davis, C. H. June, and M. K. Racke. 1996. CTLA-4 blockade enhances clinical disease and cytokine production during experimental allergic encephalomyelitis. J. Immunol. 157:1333.
25. Hurwitz, A. A., T. J. Sullivan, M. F. Krummel, R. A. Sobel, and J. P. Allison. 1997. Specific blockade of CTLA-4/B7 interactions results in exacerbated clinical and histologic disease in an actively-induced model of experimental allergic encephalomyelitis. J. Neuroimmunol. 73:57.
26. Yanagawa, T., Y. Hidaka, V. Guimaraes, M. Soliman, and L. J. DeGroot. 1995. CTLA-4 gene polymorphism associated with Graves' disease in a Caucasian population. J. Clin. Endocrinol. Metab. 80:41.
27. Donner, H., H. Rau, P. G. Walfish, J. Braun, T. Siegmund, R. Finke, J. Herwig, K. H. Usadel, and K. Badenhoop. 1997. CTLA4 alanine-17 confers genetic susceptibility to Graves' disease and to type 1 diabetes mellitus. J. Clin. Endocrinol. Metab. 82:143.
28. Tan, E. M., A. S. Cohen, J. F. Fries, D. J. McShane, N. F. Rothfield, J. G. Schaller, N. Talal, and R. J. Winchester. 1982. The 1982 revised criteria for the classification of systemic lupus erythematosus. Arthritis Rheum. 25: 1271.
29. Arnett F. C., S. M. Edworthy, D. A. Bloch, D. J. McShane, J. F. Fries, N. S. Cooper, L. A. Healey, S. R. Kaplan, M. H. Liang, H. S. Luthra, et al. 1988. The American Rheumatism Association 1987 revised criteria for the classification of rheumatoid arthritis. Arthritis Rheum. 31:315.
30. Subcommittee for Scleroderma Criteria of the American Rheumatism Association Diagnostic and Therapeutic Criteria Committee. 1980. Preliminary criteria for the classification of systemic sclerosis (scleroderma). Arthritis Rheum. 23: 581.
31. International Study Group for Behçet's Disease. 1990. Criteria for diagnosis of Behçet's disease. Lancet 335:1078.
32. Homma, M., T. Tojo, M. Akizuki, and H. Yamagata. 1986. Criteria for Sjögren's syndrome in Japan. Scand. J. Rheumatol. 61(Suppl.):26.
33. Dariavach, P., M. G. Mattei, P. Golstein, and M. P. Lefranc. 1988. Human Ig superfamily CTLA-4 gene: chromosomal localization and identity of protein sequence between murine and human CTLA-4 cytoplasmic domains. Eur. J. Immunol. 18:1901.
34. Lee, K. P., C. Taylor, B. Petryniak, L. A. Turka, C. H. June, and C. B. Thompson. 1990. The genomic organization of the CD28 gene: implications for the regulation of CD28 mRNA expression and heterogeneity. J. Immunol. 145:344.
35. Freeman, G. J., A. S. Freedman, J. M. Segil, G. Lee, J. F. Whitman, and L. M. Nadler. 1989. B7, a new member of the Ig superfamily with unique expression on activated and neoplastic B cells. J. Immunol. 143:2714.
36. Freeman, G. J., J. G. Gribben, V. A. Boussiotis, J. W. Ng, V. A. Restivo, L. A. Lombard, G. S. Gray, and L. M. Nadler. 1993. Cloning of B7-2: a CTLA-4 counter receptor that costimulates human T cell proliferation. Science 262:909.
37. Azuma, M., D. Ito, H. Yagita, K. Okumura, J. H. Phillips, L. L. Lanier, and C. Somoza. 1993. B70 antigen is a second ligand for CTLA-4 and CD28. Nature 366:76.
38. Kato, T., S. Suzuki, K. Oda, K. Nishioka, and K. Yamamoto. 1994. An improved expression vector producing a thrombin-cleavable fusion protein. Mol. Biol. 13: 85.
39. Stanley, K. K., and J. P. Luzio. 1984. Construction of a new family of high efficiency bacterial expression vectors: identification of cDNA clones coding for human liver proteins. EMBO J. 3:1429.
40. Yamamoto, K., H. Miura, Y. Moroi, S. Yoshinoya, M. Goto, K. Nishioka, and T. Miyamoto. 1988. Isolation and characterization of a complementary DNA expressing human U1 small nuclear ribonucleoprotein C polypeptide. J. Immunol. 140:311.
41. Olmsted, J. B. 1981. Affinity purification of antibodies from diazotized paper blots of heterogeneous protein samples. J. Biol. Chem. 256:11955.
42. Karasuyama, H., and F. Melchers. 1988. Establishment of mouse cell lines which constitutively secrete large quantities of interleukin 2, 3, 4 or 5, using modified cDNA expression vectors. Eur. J. Immunol. 18:97.
43. Azuma, M., M. Cayabyab, D. Buck, J. H. Phillips, and L. L. Lanier. 1992. CD28 interactions with B7 costimulates primary allogeneic proliferative responses and cytotoxicity mediated by small, resting T lymphocytes. J. Exp. Med. 175:353.
44. Kaneko, F., Y. Takahashi, Y. Muramatsu, and Y, Miura. 1985. Immunological studies on aphthous ulcer and erythema nodosum-like eruption in Behçet's disease. Br. J. Dermatol. 113:303.
45. Yamana, S., S. L. Jones, T. Shimamoto, T. Shiota, T. Aoyama, and K. Takasugi. 1986. Immunohistochemical analysis of lymphocytes infiltrating the terminal ileum in patients with Behçet's disease. In Recent Advances in Behçet's Disease. T. Lehner and C. G. Barnes, eds. Royal Society of Medicine Services, London, p. 129.
46. + lymphocyte involvement in ocular Behçet's disease. Autoimmunity 12:201.
47. Sakane, T., H. Kotani, S. Takada, and T. Tsunematsu. 1982. Functional aberration of T cell subsets in patients with Behçet's disease. Arthritis Rheum. 25:1343.
48. Verwilghen, J., R. Lovis, B. M. De, P. S. Linsley, G. K. Haines, A. E. Koch, and R. M. Pope. 1994. Expression of functional B7 and CTLA4 on rheumatoid synovial T cells. J. Immunol. 153:1378.
49. Kato, T., K. Yamamoto, H. Takeuchi, M. Okubo, E. Hara, S. Nakada, K. Oda, K. Ito, and K. Nishioka. 1993. Identification of a universal B cell epitope on DNA topoisomerase 1, an autoantigen associated with scleroderma. Arthritis Rheum. 36:1580.
50. Kato, T., H. Sasakawa, S. Suzuki, M. Shirako, F. Tashiro, K. Nishioka, and K. Yamamoto. 1995. Autoepitopes of the 52kd SS-A/Ro molecule. Arthritis Rheum. 38:990.
51. Harper, K., C. Balzano, E. Rouvier, M. G. Mattei, M. F. Luciani, and P. Golstein. 1991. CTLA-4 and CD28 activated lymphocyte molecules are closely related in both mouse and human as to sequence, message expression, gene structure, and chromosomal location. J. Immunol. 147:1037.
52. Perez, V. L., P. L. Van, A. Biuckians, X. X. Zheng, T. B. Strom, and A. K. Abbas. 1997. Induction of peripheral T cell tolerance in vivo requires CTLA-4 engagement. Immunity 6:411.