Photodynamically induced effects in colon carcinoma cells (WiDr) by endogenous photosensitizers generated by incubation with 5-aminolaevulinic acid

Journal of Photochemistry and Photobiology B: Biology

Volumn 49, Issue 2-3, 1999, Pages 162-170

  Gederaas, Odrun A ^a   Rasch, Monique H ^b   Berg, Kristian ^c   Lagerberg, Johan W M ^b   Dubbelman, Tom M A R ^b  

^a TRONDHEIM UNIVERSITY HOSPITAL   (Norway)

^b LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

^c INSTITUTE OF CANCER RESEARCH   (Norway)

Author keywords

Aminolaevulinic acid; Fluorescence; Illumination; Photodynamic therapy; Photoinactivation; Protoporphyrin; Succinylacetone; WiDr cells

Indexed keywords

ACID PHOSPHATASE; ADENOSINE TRIPHOSPHATE; AMINOLEVULINIC ACID; CELL ENZYME; GLUCOSAMINIDASE; GLYCERALDEHYDE 3 PHOSPHATE DEHYDROGENASE; LACTATE DEHYDROGENASE; OXIDOREDUCTASE; PHOTOSENSITIZING AGENT; PROTOPORPHYRIN; RHODAMINE 123; SUCCINATE DEHYDROGENASE;

ARTICLE; CARCINOMA CELL; CELLULAR DISTRIBUTION; CLONOGENESIS; COLON CARCINOMA; CONFOCAL LASER MICROSCOPY; CONTROLLED STUDY; CYTOSOL; ENZYME ACTIVITY; FETAL CALF SERUM; HUMAN; HUMAN CELL; ILLUMINATION; INCUBATION TIME; LYSOSOME; OXYGEN CONSUMPTION; PRIORITY JOURNAL;

ADENOSINE TRIPHOSPHATE; AMINOLEVULINIC ACID; COLONIC NEOPLASMS; FLUORESCENT DYES; HEPTANOATES; HUMANS; MICROSCOPY, CONFOCAL; MICROSCOPY, FLUORESCENCE; OXYGEN CONSUMPTION; PHOTOCHEMOTHERAPY; PHOTOSENSITIZING AGENTS; PROTOPORPHYRINS; RHODAMINE 123; TIME FACTORS; TUMOR CELLS, CULTURED; TUMOR MARKERS, BIOLOGICAL;

EID: 0033120303     PISSN: 10111344     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1011-1344(99)00051-2     Document Type: Article

References (36)

1. R.H. Pottier, Y.F.A. Chow, J.P. Laplante, T.G. Truscott, J.C. Kennedy, L.A. Beiner, Non-invasive technique for obtaining fluorescence excitation and emission spectra in vivo, Photochem. Photobiol. 44 (1986) 679-687.
2. J.C. Kennedy, R.H. Pottier, D.C. Ross, Photodynamic therapy with endogenous protoporphyrin IX: Basic principles and present clinical experience, J. Photochem. Photobiol. B: Biol. 6 (1990) 143-148.
3. Q. Peng, K. Berg, J. Moan, M. Kongshaug, J.M. Nesland, 5-Aminolevulinic acid-based photodynamic therapy: Principles and experimental research, Photochem. Photobiol. 65 (1997) 235-251.
4. Q. Peng, T. Warloe, K. Berg, J. Moan, M. Kongshaug, K.-E. Giercksky, J. Nesland, 5-Aminolevulinic acid-based photodynamic therapy: Clinical research and future challenges, Cancer 79 (1997) 2282-2308.
5. Z. Malik, H. Lugaci, Destruction of erythroleukemic cells by photoactivation of endogenous porphyrins, Brit. J. Cancer. 56 (1987) 589-595.
6. Z. Malik, B. Ehrenberg, A. Faraggi, Inactivation of erythropoietic, lymphatic and myelocytic leukemic cells by photoexitation of endogenous porphyrins, J. Photochem. Photobiol. B: Biol. 4 (1989) 195-205.
7. J. Hanania, Z. Malik, The effect of EDTA and serum on endogenous-porphyrin accumulation and photodynamic sensitization of human K562 leukemic cells, Cancer Lett. 65 (1992) 127-131.
8. J. Bedwell, A.J. MacRobert, D. Phillips, S.G. Bown, Fluorescence distribution and photodynamic effect of 5-ALA-induced PpIX in the DMH rat colonie tumor model, Br. J. Cancer 65 (1992) 818-824.
9. 2+-ATPase and tryptophan oxidation, Photochem. Photobiophys. 8 (1984) 143-151.
10. N. Schoenfeld, R. Mamet, Y. Nordenberg, M. Shafran, T. Babushkin, Z. Malik, Protophorphyrin biosynthesis in melanoma B16 cells stimulated by 5-aminolevulinic acid and chemical inducers: Characterization of photodynamic inactivation. Int. J. Cancer 56 (1994) 106-112.
11. A.M. del C.Battle, Porphyrins, porphyrias, cancer and photodynamic therapy - A model for carcinogenesis, J. Photochem. Photobiol. B: Biol. 20 (1993) 5-22.
12. J.C. Kennedy, R.H. Pottier, Endogenous protoporphyrin IX, a clinically useful photosensitizer for photodynamic therapy, J. Photochem. Photobiol. B: Biol. 14 (1992) 275-292.
13. S.L. Gibson, R.S. Murant, M.D. Chazen, M.E. Kelly, R. Hilf, In vitro photosensitization of tumour cell enzymes by Photofrin II administered in vivo, Br. J. Cancer 59 (1989) 47-53.
14. R. Hilf, N.W. Warne, D.B. Smail, S.L. Gibson, Photodynamic inactivation of selected intracellular enzymes by hematoporphyrin derivative and their relationship to tumor cell viability in vitro, Cancer Lett. 24 (1984) 165-172.
15. R.S. Murant, S.L. Gibson, R. Hilf, Photosensitizing effects of photofrin II on the site-selected mitochondrial enzymes adenylate kinase and monoamine oxidase, Cancer Res. 47 (1987) 4323-4328.
16. R Hilf, R.S. Murant, A. Narayanan, S.L. Gibson, Relationship of mitochondrial function and cellular adenosine triphosphate levels to hematoporphyrin derivative-induced photosensitization in R3230AC mammary tumors, Cancer Res. 46 (1986) 211-217.
17. J.P. Boegheim, H. Scholte, T.M. Dubbelman, E. Beems, A.K. Raap, J. van Steveninck, Photodynamic effects of hematoporphyrin-derivative on enzyme activities of murine L929 fibroblasts, J. Photochem. Photobiol. B: Biol. 1 (1987) 61-73.
18. O.H. Lowry, N.J. Rosebrough, A.L. Farr, R.J. Randall, Protein measurements with the folin phenol reagent, J. Biol. Chem. 193 (1951) 265-275.
19. Z. Darzynkiewicz, L. Stainano-Coico, M.R. Melamed, Increased mitochondrial uptake of rhodamine 123 during lymphocyte stimulation, Proc. Natl. Acad. Sci. USA 78 (1981) 2383-2387.
20. W.R. Seits, M.P. Neary, Recent advances in bioluminescence and chemiluminescence assay, Methods Biochem. Anal. 23 (1976) 161-188.
21. I. Schevchuk, V. Shekulayev, L. Chekulayeva, Enhancement of the efficiency of photodynamic therapy of tumors by t-butyl-4-hydroxyanisole, J. Photochem. Photobiol. B: Biol. 45 (1998) 136-143.
22. R. Wu, E. Racker, Regulatory mechanisms in carbohydrate metabolism. III. Limiting factors in glycolysis of ascites tumor cells, J. Biol. Chem. 234 (1959) 1029-1035.
23. H.U. Bergmeyer, E. Bernt, UV-assay with pyruvate and NADH, in: H.U. Bergmeyer (Ed.), Methods in Enzymatic Analysis, Academic Press, New York, 1974, pp. 574-579.
24. R.J. Pennington, Biochemistry of dystropic muscle, Biochem. J. 80 (1961) 649-654.
25. B. Hess, H.J. Wieker, Pyruvate kinase from yeast, in: H.U. Bergmeyer (Ed.), Methods in Enzymatic Analysis, Academic Press, New York, 1974, pp. 778-783.
26. J. Carmichael, W.G. DeGraff, A.F. Gazadar, J.D. Minna, J.B. Mitchell, Evaluation of a tetrazolium-based semiautomated colorimetric assay: Assessment of chemosensitivity testing, Cancer Res. 47 (1987) 936-942.
27. S. Iinuma, S.S. Farshi, B. Ortel, T. Hasan, A mechanistic study of cellular photodestruction with 5-aminolaevulinic acid-induced porphyrin, Br. J. Cancer 70 (1994) 21-28.
28. H. Fukuda, A.M.C. Battle, P.A. Riley, Kinetics of porphyrin accumulation in cultured epithelial cells exposed to 5-ALA, Int. J. Biochem. 25 (1993) 1407-1410.
29. K. Berg, H. Anholt, Ø. Bech, J. Moan, Inhibition of ferrochelatase activity in 5-aminolevulinic acid-treated cells by iron chelators, Br. J. Cancer 74 (1996) 688-697.
30. K. Berg, Mechanism of cell damage in photodynamic therapy, in: H. Honigsmann, G. Jori, A. Young (Eds.), The Fundamental Bases of Phototherapy, OEMF, Milan, 1996, pp. 181-207.
31. I. Shevchuk, V. Chekulayev, J. Moan, K. Berg, Effects of the inhibitors of energy metabolism, lonidamine and levamisole, on 5-aminolevulinic-induced photochemotherapy, Int. J. Cancer 67 (1996) 791-799.
32. A. Atlante, S. Passarella, E. Quagliariello, G. Moreno, C. Salet, Haematoporphyrin derivative (Photofrin II) photosensitization of isolated mitochondria: Inhibition of ADP/ATP translocator, J. Photochem. Photobiol. B: Biol. 4 (1989) 35-46.
33. R. Hilf, D.B. Smail, R.S. Murant, P.B. Leakey, S.L. Gibson, Hematoporphyrin derivative-induced photosensitivity of mitochondrial succinate dehydrogenase and selected cytosolic enzyme of R3230AC mammary adenocarcinomas of rats, Cancer Res. 44 (1984) 1483-1488.
34. S. Sano, S. Granick, Mitochondrial coproporphyrinogen oxidase and protoporphyrin formation, J. Biol. Chem. 236 (1961) 1173-1180.
35. R. Poulson, W.J. Polglase, The enzymic conversion of protoporphyrinogen IX to protoporphyrin IX. Protoporphyrinogen oxidase activity in mitochondrial extracts of saccharomyces cerevisiae, J. Biol. Chem. 250 (1975) 1269-1274.
36. J.P. Boegheim, J.W.M. Lagerberg, T.M.A.R. Dubbelman, K. Tjissen, H.J. Tanke, J. Van der Meulen, J. Van Steveninck, Photodynamic effects of hematoporphyrin derivative on the uptake of rhodamine 123 by mitochondria of intact murine L929 fibroblasts and chinese hamster ovary K1 cells, Photochem. Photobiol. 48 (1988) 613-620.