Functional and molecular characterization of a volume-sensitive chloride current in rat brain endothelial cells

Journal of Physiology

Volumn 516, Issue 1, 1999, Pages 75-84

  Von Weikersthal, Sophia F ^a   Barrand, Margery A ^a   Hladky, Stephen B ^a  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

4,4' DIISOTHIOCYANATOSTILBENE 2,2' DISULFONIC ACID; 5 NITRO 2 (3 PHENYLPROPYLAMINO)BENZOIC ACID; ADENOSINE TRIPHOSPHATE; ANTIESTROGEN; BROMIDE; CALCIUM ION; CHLORIDE CHANNEL; CHLORIDE CHANNEL BLOCKING AGENT; CHLORIDE ION; FLUORIDE; HYPOTONIC SOLUTION; IODIDE; MESSENGER RNA; PHORBOL DIBUTYRATE; PROTEIN KINASE C; TAMOXIFEN; VERAPAMIL;

ANIMAL CELL; ANION TRANSPORT; ARTICLE; BRAIN CELL; CALCIUM CELL LEVEL; CELL VOLUME; CHLORIDE CURRENT; CHLORIDE TRANSPORT; CONTROLLED STUDY; DEPOLARIZATION; ENDOTHELIUM CELL; ENZYME ACTIVATION; MALE; NONHUMAN; PATCH CLAMP; PRIORITY JOURNAL; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; ANIMAL TISSUE; BRAIN CAPILLARY ENDOTHELIAL CELL; CELL MEMBRANE DEPOLARIZATION; CHANNEL GATING; MUSCLE HYPOTONIA; OSMOLARITY; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN FUNCTION; VOLTAGE CLAMP TECHNIQUE;

EID: 0033119964     PISSN: 00223751     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1469-7793.1999.075aa.x     Document Type: Article

References (37)

1. ABBOTT, N. J., HUGHES, C. C. W., REVEST, P. A. & GREENWOOD, J. (1992). Development and characterisation of a rat brain capillary endothelial culture: towards an in vitro blood-brain barrier. Journal of Cell Science 103, 23-37.
2. ACKERMAN, M. J., WICKMAN, K. D. & CLAPHAM, D. E. (1994). Hypotonicity activates a native chloride current in Xenopus oocytes. Journal of General Physiology 103, 153-179.
3. - currents are activated by cell swelling but do not contribute to cell volume regulation. Cancer Research 54, 618-622.
4. BARRAND, M. A., ROBERTSON, K. J. & VON WEIKERSTHAL, S. F. (1995). Comparisons of P-glycoprotein expression in isolated rat brain microvessels and in primary cultures of endothelial cells derived from microvasculature of rat brain, epididymal fat pad and from aorta. FEBS Letters 374, 179-183.
5. - transport by human nonpigmented ciliary epithelial cells. Journal of Membrane Biology 150, 197-208.
6. DONG, Y., CHEN, G., DURÁN, G. E., KOUYAMA, K., CHAO, A. C., SIKIC, B. I., GOLLAPUDI, S. V., GUPTA, S. & GARDNER, P. (1994). Volume-activated chloride current is not related to P-glycoprotein overexpression. Cancer Research 54, 5029-5039.
7. DUAN, D., WINTER, C., COWLEY, S., HUME, J. R. & HOROWITZ, B. (1997). Molecular identification of a volume-regulated chloride channel. Nature 390, 417-421.
8. GILL, D. R., HYDE, S. C., HIGGINS, C. F., VALVERDE, M. A., MINTENG, G. M. & SEPULVEDA, F. V. (1992). Separation of drug transport and chloride channel functions of human multidrug resistance P-glycoprotein. Cell 71, 23-32.
9. GOSLING, M., SMITH, J. W. & POYNER, D. R. (1995). Characterization of a volume-sensitive chloride current in rat osteoblast-like (ROS 17/2.8) cells. Journal of Physiology 485, 671-682.
10. GRÜNDER, S., THIEMANN, A., PUSCH, M. & JENTSCH, T. J. (1992). Regions involved in the opening of ClC-2 chloride channel by voltage and cell volume. Nature 360, 759-762.
11. GSCHWENTNER, M., NAGEL, U. O., WÖLL, E., SCHMARIDA, A., RITTER, M. & PAULMICHL, M. (1995). Antisense oligonucleotides suppress cell-volume-induced activation of chloride channels. Pflügers Archiv 430, 464-470.
12. HAN, E. S., VANOYE, C. G., ALTENBERG, G. A. & REUSS, L. (1996). P-glycoprotein-associated chloride currents revealed by specific block by an anti-P-glycoprotein antibody. American Journal of Physiology 270, C1370-1378.
13. HOFFMANN, E. K. & DUNHAM, P. B. (1995). Membrane mechanisms and intracellular signalling in cell volume regulation. International Review of Cytology 161, 173-262.
14. KAWASAKI, M., UCHIDA, S., MONKAWA, T., MIYAWAKI, A., MIKOSHIBA, K., MARUMO, F. & SASAKI, S. (1994). Cloning and expression of a protein kinase C-regulated chloride channel abundantly expressed in rat brain neuronal cells. Neuron 12, 597-604.
15. Cln. Cell 76, 439-448.
16. KRAPIVINSKY, G., PU, W., WICKMAN, K., KRAPIVINSKY, L. & CLAPHAM, D. E. (1998). pICln binds to a mammalian homolog of a yeast protein involved in regulation of cell morphology. Journal of Biological Chemistry 273, 10811-10814.
17. - channel from renal cell line A6. American Journal of Physiology 273, C1176-1185.
18. LORENZ, C., PUSCH, M. & JENTSCH, T. J. (1996). Heteromultimeric ClC chloride channels with novel properties. Proceedings of the National Academy of Sciences of the USA 93, 13362-13366.
19. 84 intestinal epithelial layers. FEBS Letters 304, 233-236.
20. MINTENIG, G. M., VALVERDE, M. A., SEPÚLVEDA, F. V., GILL, D. R., HYDE, S. C., KIRK, J. & HIGGINS, C. F. (1993). Specific inhibitors distinguish the chloride channel and drug transporter functions associated with the human multidrug resistance P-glycoprotein, Receptors and Channels 1, 805-313.
21. - channels. General Pharmacology 27, 1131-1140.
22. - currents in different mammalian non-excitable cell types. Pflügers Archiv 428, 364-371.
23. - channel: fresh start to the molecular identity and volume sensor. American Journal of Physiology 273, C755-789.
24. PAULMICHL, M., LI, Y., WICKMAN, K., ACKERMAN, M., PERALTA, E. & CLAPHAM, D. (1992). New mammalian chloride channel identified by expression cloning. Nature 356, 238-241.
25. SAMBROOK, J., FRITSCH, E. F. & MANIATIS, T. (1989). Molecular Cloning. A Laboratory Manual, 2nd edn. Cold Spring Harbor Laboratory Press.
26. SCHMIEDER, S., LINDENTHAL, S., BANDERALI, U. & EHRENFELD, J. (1998). Characterization of the putative chloride channel xClC-5 expressed in Xenopus laevis oocytes and comparison with endogenous chloride currents. Journal of Physiology 511, 379-393.
27. STEINMEYER, K., SCHWAPPACH, B., BENS, M., VANDEWALLE, A. & JENTSCH, T. J. (1995). Cloning and functional expression of rat CLC-5, a chloride channel related to kidney disease. Journal of Biological Chemistry 270, 31172-31177.
28. STRANGE, K., EMMA, F. & JACKSON, P. S. (1996). Cellular and molecular physiology of volume-sensitive anion channels. American Journal of Physiology 270, C711-730.
29. THIEMANN, A., GRÜNDER, S., PUSCH, M. & JENTSCH, T. J. (1992). A chloride channel widely expressed in epithelial and non-epithelial cells. Nature 356, 57-60.
30. TOMINAGA, M., TOMINAGA, T., MIWA, A. & OKADA, Y. (1995). Volume-sensitive chloride channel activity does not depend on endogenous P-glycoprotein. Journal of Biological Chemistry 270, 27887-27893.
31. VALVERDE, M. A., BOND, T. D., HARDY, S. P., TAYLOR, J. C., HIGGINS, C. F., ALTAMIRANO, J. & ALVAREZ-LEEFMANS, F. J. (1996). The multidrug resistance P-glycoprotein modulates cell regulatory volume decrease. EMBO Journal 15, 4460-4468.
32. VALVERDE, M. A., DIAZ, M., SEPÚLVEDA, F. V., GILL, D. R., HYDE, S. C. & HIGGINS, C. F. (1992). Volume-regulated chloride channels associated with the human multidrug-resistance P-glycoprotein. Nature 355, 830-833.
33. VON WEIKERSTHAL, S. F., HAINSWORTH, A. H., HENDERSON, R. M., HLADKY, S. B. & BARRAND, M. A. (1996). Hypotonicity-induced changes in chloride currents in endothelial cells cultured from rat brain microvasculature. Journal of Physiology 494.P, 58P.
34. VON WEIKERSTHAL, S. F., HICKMANM, M. E., HLADKY, S. B. & BARRAND, M. A. (1997). Hypotonicity-induced changes in anion permeability of cultured rat brain endothelial cells. Biochimica et Biophysica Acta 1325, 99-107.
35. WU, J., ZHANG, J. J., KOPPEL, H. & JACOB T. J. C. (1996). P-glycoprotein regulates a volume-activated chloride current in bovine non-pigmented ciliary epithelial cells. Journal of Physiology 491, 743-755.
36. YAMAZAKI, J., DUAN, D., JANIAK, F., KUENZLI, K., HOROWITZ, B. & HUME, J. R. (1998). Functional and molecular expression of volume-regulated chloride channels in canine vascular smooth muscle cells. Journal of Physiology 507, 729-736.
37. ZHANG, J. J., JACOB, T. J. C., VALVERDE, M. A., HARDY, S. P., MINTENIG, G. M., SEPÚLVEDA, F. V., GILL, D. R., HYDE, S. C., TREZISE, A. E. O. & HIGGINS, C. F. (1994). Tamoxifen blocks chloride channels. Journal of Clinical Investigation 94, 1690-1697.