메뉴 건너뛰기




Volumn 59, Issue 7 SUPPL., 1999, Pages

The role of chimeric paired box transcription factors in the pathogenesis of pediatric rhabdomyosarcoma

Author keywords

[No Author keywords available]

Indexed keywords

HYBRID PROTEIN; TRANSCRIPTION FACTOR;

EID: 0033118781     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Conference Paper
Times cited : (61)

References (38)
  • 1
    • 0000102827 scopus 로고    scopus 로고
    • Rhabdomyosarcoma and the undifferentiated sarcomas
    • P. A. Pizzo and P. G. Poplack (eds.), Philadelphia: Lippincott-Raven
    • Wexler, L. H., and Helman, L. J. Rhabdomyosarcoma and the undifferentiated sarcomas. In: P. A. Pizzo and P. G. Poplack (eds.), Principles and Practice of Pediatric Oncology, Ed. 3, pp. 799-829. Philadelphia: Lippincott-Raven, 1997.
    • (1997) Principles and Practice of Pediatric Oncology, Ed. 3 , pp. 799-829
    • Wexler, L.H.1    Helman, L.J.2
  • 3
    • 0027534945 scopus 로고
    • Rearrangement of the PAX3 paired box gene in the paediatric solid tumour alveolar rhabdomyosarcoma
    • Barr, F. G., Galili, N., Holick, J., Siegel, J. A., Rovera, G., and Emanuel, B. S. Rearrangement of the PAX3 paired box gene in the paediatric solid tumour alveolar rhabdomyosarcoma. Nat. Genet., 3: 113-117, 1993.
    • (1993) Nat. Genet. , vol.3 , pp. 113-117
    • Barr, F.G.1    Galili, N.2    Holick, J.3    Siegel, J.A.4    Rovera, G.5    Emanuel, B.S.6
  • 4
    • 0028366153 scopus 로고
    • PAX. Genes for mice and men
    • Tremblay, P., and Gruss, P. PAX. Genes for mice and men. Pharmacol. Ther., 61: 205-226, 1994.
    • (1994) Pharmacol. Ther. , vol.61 , pp. 205-226
    • Tremblay, P.1    Gruss, P.2
  • 6
    • 0027366917 scopus 로고
    • Fusion of PAX3 to a member of the forkhead family of transcription factors in human alveolar rhabdomyosarcoma
    • Shapiro, D. N., Sublett, J. E., Li, B., Downing, J. R., and Naeve, C. W. Fusion of PAX3 to a member of the forkhead family of transcription factors in human alveolar rhabdomyosarcoma. Cancer Res., 53: 5108-5112, 1993.
    • (1993) Cancer Res. , vol.53 , pp. 5108-5112
    • Shapiro, D.N.1    Sublett, J.E.2    Li, B.3    Downing, J.R.4    Naeve, C.W.5
  • 7
    • 17344379513 scopus 로고    scopus 로고
    • Five years on the wings of fork head
    • Kaufmann, E., and Knochel, W. Five years on the wings of fork head. Mech. Dev., 57: 3-20, 1996.
    • (1996) Mech. Dev. , vol.57 , pp. 3-20
    • Kaufmann, E.1    Knochel, W.2
  • 8
    • 0028881603 scopus 로고
    • The PAX3-FKHR fusion protein created by the t(2;13) translocalion in alveolar rhabdomyosarcoma is a more potent transcriptional activator than PAX3
    • Fredericks, W. J., Galili, N., Mukhopadhyay, S., Rovera, G., Bennicelli, J., Barr, F. G., and Rauscher, F. J., III. The PAX3-FKHR fusion protein created by the t(2;13) translocalion in alveolar rhabdomyosarcoma is a more potent transcriptional activator than PAX3. Mol. Cell. Biol., 15: 1522-1535, 1995.
    • (1995) Mol. Cell. Biol. , vol.15 , pp. 1522-1535
    • Fredericks, W.J.1    Galili, N.2    Mukhopadhyay, S.3    Rovera, G.4    Bennicelli, J.5    Barr, F.G.6    Rauscher F.J. III7
  • 9
    • 0028965553 scopus 로고
    • Genomic structure of the human PAX3 gene: DNA sequence analysis of the region disrupted in alveolar rhabdomyosarcoma
    • Macina, R. A., Barr, F. G., Galili, N , and Rielhman, H. C. Genomic structure of the human PAX3 gene: DNA sequence analysis of the region disrupted in alveolar rhabdomyosarcoma. Genomics, 26: 1-8, 1995.
    • (1995) Genomics , vol.26 , pp. 1-8
    • Macina, R.A.1    Barr, F.G.2    Galili, N.3    Rielhman, H.C.4
  • 10
    • 0032053388 scopus 로고    scopus 로고
    • Structural analysis of PAX3 genomic rearrangements in alveolar rhabdomyosarcoma
    • Barr, F. G., Nauta, L. E., and Hollows, J. C. Structural analysis of PAX3 genomic rearrangements in alveolar rhabdomyosarcoma. Cancer Genet. Cytogenet., 102: 32-39, 1998.
    • (1998) Cancer Genet. Cytogenet. , vol.102 , pp. 32-39
    • Barr, F.G.1    Nauta, L.E.2    Hollows, J.C.3
  • 11
    • 0028867940 scopus 로고
    • Structural characterization of the FKHR gene and its rearrangement in alveolar rhabdomyosarcoma
    • Davis, R. J., Bennicelli, J. L., Macina, R. A., Nycum, L. M., Biegel, J. A., and Barr, F. G. Structural characterization of the FKHR gene and its rearrangement in alveolar rhabdomyosarcoma. Hum. Mol. Genet., 4: 2355-2362, 1995.
    • (1995) Hum. Mol. Genet. , vol.4 , pp. 2355-2362
    • Davis, R.J.1    Bennicelli, J.L.2    Macina, R.A.3    Nycum, L.M.4    Biegel, J.A.5    Barr, F.G.6
  • 12
    • 0028364374 scopus 로고
    • Fusion of PAX7 to FKHR by the variant t(1;13)(p36;q14) translocation in alveolar rhabdomyosarcoma
    • Davis, R. J., D'Cruz, C. M., Lovell, M. A., Biegel, J. A., and Barr, F. G. Fusion of PAX7 to FKHR by the variant t(1;13)(p36;q14) translocation in alveolar rhabdomyosarcoma. Cancer Res., 54: 2869-2872, 1994.
    • (1994) Cancer Res. , vol.54 , pp. 2869-2872
    • Davis, R.J.1    D'Cruz, C.M.2    Lovell, M.A.3    Biegel, J.A.4    Barr, F.G.5
  • 13
    • 0029618877 scopus 로고
    • A consensus polymerase chain reaction-oligonucleotide hybridization approach for the detection of chromosomal translocations in pediatric bone and soft tissue cancers
    • Barr, F. G., Xiong, Q-B., and Kelly, K. A consensus polymerase chain reaction-oligonucleotide hybridization approach for the detection of chromosomal translocations in pediatric bone and soft tissue cancers. Am. J. Clin. Pathol., 104: 627-633, 1995.
    • (1995) Am. J. Clin. Pathol. , vol.104 , pp. 627-633
    • Barr, F.G.1    Xiong, Q.-B.2    Kelly, K.3
  • 14
    • 0028928079 scopus 로고
    • Detection of the t(2;13)(q35;q14) chromosomal translocation and PAX3-FKHR fusion in alve-olar rhabdomyosarcoma by fluorescence in situ hybridization
    • Biegel, J. A., Nycum, L. M., Valentine, V., Barr, F. G., and Shapiro, D. N. Detection of the t(2;13)(q35;q14) chromosomal translocation and PAX3-FKHR fusion in alve-olar rhabdomyosarcoma by fluorescence in situ hybridization. Genes Chromosomes Cancer, 12: 186-192, 1995.
    • (1995) Genes Chromosomes Cancer , vol.12 , pp. 186-192
    • Biegel, J.A.1    Nycum, L.M.2    Valentine, V.3    Barr, F.G.4    Shapiro, D.N.5
  • 16
    • 0030059906 scopus 로고    scopus 로고
    • In vivo amplification of the PAX3-FKHR and PAX7-FKHR fusion genes in alveolar rhabdomyosarcoma
    • Barr, F. G., Nauta, L. E., Davis, R. J., Schafer, B. W., Nycum, L. M., and Biegel, J. A. In vivo amplification of the PAX3-FKHR and PAX7-FKHR fusion genes in alveolar rhabdomyosarcoma. Hum. Mol. Genet., 5: 15-21, 1996.
    • (1996) Hum. Mol. Genet. , vol.5 , pp. 15-21
    • Barr, F.G.1    Nauta, L.E.2    Davis, R.J.3    Schafer, B.W.4    Nycum, L.M.5    Biegel, J.A.6
  • 18
    • 0028840711 scopus 로고
    • Detection of chimeric transcripts in desmoplastic small round cell tumor and related developmental tumors by reverse transcriptase polymerase chain reaction
    • de Alava, E., Ladanyi, M., Rosai, J., and Gerald, W. L. Detection of chimeric transcripts in desmoplastic small round cell tumor and related developmental tumors by reverse transcriptase polymerase chain reaction. Am. J. Pathol., 147: 1584-1591, 1995.
    • (1995) Am. J. Pathol. , vol.147 , pp. 1584-1591
    • De Alava, E.1    Ladanyi, M.2    Rosai, J.3    Gerald, W.L.4
  • 19
    • 0029738704 scopus 로고
    • Detection of the t(2;13) chromosomal translocation in alveolar rhabdomyosarcoma using the reverse transcriptase-polymerase chain reaction
    • Arden, K. C., Anderson, M. J., Finckenstein, F. G., Czekay, S., and Cavenee, W. K. Detection of the t(2;13) chromosomal translocation in alveolar rhabdomyosarcoma using the reverse transcriptase-polymerase chain reaction. Genes Chromosomes Cancer, 16: 254-260, 1995.
    • (1995) Genes Chromosomes Cancer , vol.16 , pp. 254-260
    • Arden, K.C.1    Anderson, M.J.2    Finckenstein, F.G.3    Czekay, S.4    Cavenee, W.K.5
  • 20
    • 0030965752 scopus 로고    scopus 로고
    • Common and variant gene fusions predict distinct clinical phenotypes in rhabdomyosarcoma
    • Kelly, K. M., Womer, R. B., Sorensen, P. H., Xiong, Q-B., and Barr, F. G. Common and variant gene fusions predict distinct clinical phenotypes in rhabdomyosarcoma. J. Clin. Oncol., 15: 1831-1836, 1997.
    • (1997) J. Clin. Oncol. , vol.15 , pp. 1831-1836
    • Kelly, K.M.1    Womer, R.B.2    Sorensen, P.H.3    Xiong, Q.-B.4    Barr, F.G.5
  • 21
    • 0030860934 scopus 로고    scopus 로고
    • Fusion genes resulting from alternative chromosomal translocations are overexpressed by gene-specific mechanisms in alveolar rhabdomyosarcoma
    • Davis, R. J., and Barr, F. G. Fusion genes resulting from alternative chromosomal translocations are overexpressed by gene-specific mechanisms in alveolar rhabdomyosarcoma. Proc. Natl. Acad. Sci. USA, 94: 8047-8051, 1997.
    • (1997) Proc. Natl. Acad. Sci. USA , vol.94 , pp. 8047-8051
    • Davis, R.J.1    Barr, F.G.2
  • 22
    • 0025162339 scopus 로고
    • HNF-3A, a hepatocyte-enriched transcription factor of novel structure is regulated transcriptionally
    • Lai, E., Prezioso, V. R., Smith, E., Litvin, O., Costa, R. H., and Darnell. J. E., Jr. HNF-3A, a hepatocyte-enriched transcription factor of novel structure is regulated transcriptionally. Genes Dev., 4: 1427-1436, 1990.
    • (1990) Genes Dev. , vol.4 , pp. 1427-1436
    • Lai, E.1    Prezioso, V.R.2    Smith, E.3    Litvin, O.4    Costa, R.H.5    Darnell J.E., Jr.6
  • 23
    • 0027322128 scopus 로고
    • Identification of nine tissue-specific transcription factors of the hepatocyte nuclear factor 3/forkhead DNA-binding-domain family
    • Clevidence, D. E., Overdier, D. G., Tao, W., Qian, X., Pani, L., Lai, E., and Costa, R. H. Identification of nine tissue-specific transcription factors of the hepatocyte nuclear factor 3/forkhead DNA-binding-domain family. Proc. Natl. Acad. Sci. USA, 90: 3948-3952, 1993.
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 3948-3952
    • Clevidence, D.E.1    Overdier, D.G.2    Tao, W.3    Qian, X.4    Pani, L.5    Lai, E.6    Costa, R.H.7
  • 24
    • 0025875226 scopus 로고
    • Pax-3, a novel murine DNa binding protein expressed during early neurogenesis
    • Goulding, M. D., Chalepakis, G., Deutsch, U., Erselius, J. R., and Gruss, P. Pax-3, a novel murine DNA binding protein expressed during early neurogenesis. EMBO J., 10: 1135-1147, 1991.
    • (1991) EMBO J. , vol.10 , pp. 1135-1147
    • Goulding, M.D.1    Chalepakis, G.2    Deutsch, U.3    Erselius, J.R.4    Gruss, P.5
  • 25
    • 0025884198 scopus 로고
    • The paired box encodes a second DNA-binding domain in the paired homeodomain protein
    • Treisman, J., Harris, E., and Desplan, C. The paired box encodes a second DNA-binding domain in the paired homeodomain protein. Genes Dev., 5: 594-604, 1991.
    • (1991) Genes Dev. , vol.5 , pp. 594-604
    • Treisman, J.1    Harris, E.2    Desplan, C.3
  • 26
    • 0027971981 scopus 로고
    • Molecular cloning and characterization of a human PAX-7 cDNa expressed in normal and neoplastic myocytes
    • Schafer, B. W., Czerny, T., Bernasconi, M., Genini, M., and Busslinger, M. Molecular cloning and characterization of a human PAX-7 cDNA expressed in normal and neoplastic myocytes. Nucleic Acids Res., 22: 4574-4582, 1994.
    • (1994) Nucleic Acids Res. , vol.22 , pp. 4574-4582
    • Schafer, B.W.1    Czerny, T.2    Bernasconi, M.3    Genini, M.4    Busslinger, M.5
  • 27
    • 0029980113 scopus 로고    scopus 로고
    • Mechanism for transcriptional gain of function resulting from chromosomal translocation in alveolar rhabdomyosarcoma
    • Bennicelli, J. L., Edwards, R. H., and Barr, F. G. Mechanism for transcriptional gain of function resulting from chromosomal translocation in alveolar rhabdomyosarcoma. Proc. Natl. Acad. Sci. USA, 93: 5455-5459, 1996.
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 5455-5459
    • Bennicelli, J.L.1    Edwards, R.H.2    Barr, F.G.3
  • 28
    • 0029154584 scopus 로고
    • Wild type PAX3 protein and the PAX3-FKHR fusion protein of alveolar rhabdomyosarcoma contain potent, structurally distinct transcriptional activation domains
    • Bennicelli, J. L., Fredericks, W. J., Wilson, R. B., Rauscher, F. J., III, and Barr, F. G. Wild type PAX3 protein and the PAX3-FKHR fusion protein of alveolar rhabdomyosarcoma contain potent, structurally distinct transcriptional activation domains. Oncogene, 11: 119-130, 1995.
    • (1995) Oncogene , vol.11 , pp. 119-130
    • Bennicelli, J.L.1    Fredericks, W.J.2    Wilson, R.B.3    Rauscher F.J. III4    Barr, F.G.5
  • 29
    • 0027452611 scopus 로고
    • The Splotch mutation interferes with muscle development in the limbs
    • Franz, T., Kothary, R., Surani. M. A., Halata, Z., and Grim, M. The Splotch mutation interferes with muscle development in the limbs. Anat. Embryol., 187: 153-160, 1993.
    • (1993) Anat. Embryol. , vol.187 , pp. 153-160
    • Franz, T.1    Kothary, R.2    Surani, M.A.3    Halata, Z.4    Grim, M.5
  • 30
    • 0028205002 scopus 로고
    • Pax-3 is required for the development of limb muscles: A possible role for the migration of dermomyotomal muscle progenitor cells
    • Camb.
    • Bober, E., Franz, T., Arnold, H. H., Gruss, P., and Tremblay, P. Pax-3 is required for the development of limb muscles: a possible role for the migration of dermomyotomal muscle progenitor cells. Development (Camb.). 120: 603-612, 1994.
    • (1994) Development , vol.120 , pp. 603-612
    • Bober, E.1    Franz, T.2    Arnold, H.H.3    Gruss, P.4    Tremblay, P.5
  • 31
    • 0028345647 scopus 로고
    • Pax-3 expression in segmental mesoderm marks early stages in myogenic cell specification
    • Camb.
    • Williams, B. A., and Ordahl, C. P. Pax-3 expression in segmental mesoderm marks early stages in myogenic cell specification. Development (Camb.), 120: 785-796, 1994.
    • (1994) Development , vol.120 , pp. 785-796
    • Williams, B.A.1    Ordahl, C.P.2
  • 32
    • 0028205049 scopus 로고
    • Regulation of Pax-3 expression in the dermomyotome and its role in muscle development
    • Camb.
    • Goulding, M., Lumsden, A., and Paquette, A. J. Regulation of Pax-3 expression in the dermomyotome and its role in muscle development. Development (Camb.), 120: 957-971, 1994.
    • (1994) Development , vol.120 , pp. 957-971
    • Goulding, M.1    Lumsden, A.2    Paquette, A.J.3
  • 33
    • 0029915990 scopus 로고    scopus 로고
    • Pax-3 is necessary for migration but not differentiation of limb muscle precursors in the mouse
    • Camb.
    • Daston, G., Lamar, E., Olivier, M., and Goulding, M. Pax-3 is necessary for migration but not differentiation of limb muscle precursors in the mouse. Development (Camb.), 122: 1017-1022, 1996.
    • (1996) Development , vol.122 , pp. 1017-1022
    • Daston, G.1    Lamar, E.2    Olivier, M.3    Goulding, M.4
  • 34
    • 0029914928 scopus 로고    scopus 로고
    • Pax3 modulates expression of the c-Met receptor during limb muscle development
    • Epstein, J. A., Shapiro, D. N., Cheng, J., Lam, P. Y., and Maas, R. L. Pax3 modulates expression of the c-Met receptor during limb muscle development. Proc. Natl. Acad. Sci. USA, 93: 4213-4218, 1996.
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 4213-4218
    • Epstein, J.A.1    Shapiro, D.N.2    Cheng, J.3    Lam, P.Y.4    Maas, R.L.5
  • 35
    • 0030018672 scopus 로고    scopus 로고
    • Expression of the met receptor tyrosine kinase in muscle progenitor cells in somites and limbs is absent in Splotch mice
    • Camb.
    • Yang, X. M., Vogan, K., Gros, P., and Park, M. Expression of the met receptor tyrosine kinase in muscle progenitor cells in somites and limbs is absent in Splotch mice. Development (Camb.). 122: 2163-2171, 1996.
    • (1996) Development , vol.122 , pp. 2163-2171
    • Yang, X.M.1    Vogan, K.2    Gros, P.3    Park, M.4
  • 36
    • 0029796402 scopus 로고    scopus 로고
    • The hybrid PAX3-FKHR fusion protein of alveolar rhabdomyosarcoma transforms fibroblasts in culture
    • Scheidler, S., Fredericks, W. J., Rauscher, F. J., III, Barr, F. G., and Vogt, P. K. The hybrid PAX3-FKHR fusion protein of alveolar rhabdomyosarcoma transforms fibroblasts in culture. Proc. Natl. Acad. Sci. USA, 93: 9805-9809, 1996.
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 9805-9809
    • Scheidler, S.1    Fredericks, W.J.2    Rauscher F.J. III3    Barr, F.G.4    Vogt, P.K.5
  • 37
    • 0029074993 scopus 로고
    • Pax3 inhibits myogenic differentiation of cultured myoblast cells
    • Epstein, J. A., Lam, P., Jepeal, L., Maas, R. L., and Shapiro, D. N. Pax3 inhibits myogenic differentiation of cultured myoblast cells. J. Biol. Chem., 270: 11719-11722, 1995.
    • (1995) J. Biol. Chem. , vol.270 , pp. 11719-11722
    • Epstein, J.A.1    Lam, P.2    Jepeal, L.3    Maas, R.L.4    Shapiro, D.N.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.