No Microsatellite Instability, but frequent LOH in liposarcomas

International Journal of Oncology

Volumn 14, Issue 4, 1999, Pages 721-726

  Schneider Stock, R ^a   Szibor, R ^a   Walter, H ^a   Plate, I ^a   Roessner, A ^a  

^a OTTO VON GUERICKE UNIVERSITY   (Germany)

Author keywords

Liposarcoma; Loss of heterozygosity; Microsatellite instability

Indexed keywords

DNA; MICROSATELLITE DNA;

ARTICLE; DNA REPAIR; GENETIC MARKER; GENETICS; HETEROZYGOSITY LOSS; HUMAN; LIPOSARCOMA; PATHOPHYSIOLOGY;

DNA REPAIR; DNA, NEOPLASM; GENETIC MARKERS; HUMANS; LIPOSARCOMA; LOSS OF HETEROZYGOSITY; MICROSATELLITE REPEATS;

EID: 0033113868     PISSN: 10196439     EISSN: None     Source Type: Journal    
DOI: 10.3892/ijo.14.4.721     Document Type: Article

References (42)

1. Thibodeau SN, Bren G and Schaid D: Microsatellite instability in cancer of the proximal colon. Science 260: 816-819, 1993.
2. Ionov Y, Peinado MA, Malkhosyan S, Shibata D and Perucho M: Ubiquitous somatic mutations in simple repeated sequences reveal a new mechanism for colonic carcinogenesis. Nature 363: 558-561, 1993.
3. Aaltonen LA, Peltomäki P, Mecklin JP, Järvinen H, Jass JR, Green JS, Lynch HT, Watson P, Tallqvist G, Juhola M, Sistonen P, Hamilton SR, Kinzler KW, Vogelstein B and De la Chapelle A: Replication errors in benign and malignant tumours from hereditary nonpolyposis colorectal cancer patients. Cancer Res 54: 1645-1648, 1994.
4. Levinson G and Gutman GA: Slipped-strand mispairing: a major mechanism for DNA sequence evolution. Mol Biol Evol 4: 203-221, 1987.
5. Hoffmann JS and Cazaux C: DNA synthesis, mismatch repair and cancer (Review). Int J Oncol 12: 377-382, 1998.
6. Honchel R, Hailing KC and Thibodeau SN: Genomic instability in neoplasia. Cell Biol 6: 45-52, 1995.
7. Mara G and Boland CR: Hereditary nonpolyposis colorectal cancer: the syndrome, the genes, and historical perspectives. J Natl Cancer Inst 87: 1114-1125, 1995.
8. Wooster R, Cleton-Jansen AM, Collins N, Mangion J, Cornelis RS, Cooper CS, Gusterson BA, Ponder BAJ, von Deimling A, Wiestler OD, Cornelisse CJ, Devilee P and Stratton MR: Instability of short tandem repeats (microsatellites) in human cancers. Nat Genet 6: 152-156, 1994.
9. Raskind WH, Conrad EU, Chansky H and Matsushita M: Loss of heterozygosity in chondrosarcomas for markers linked to hereditary multiple exostoses loci on chromosomes 8 and 11. Am J Hum Genet 56: 1132-1139, 1995.
10. Belchis DA, Meece C, Benko FA, Rogan PK, Williams RA and Gocke CD: Loss of heterozygosity and microsatellite instability at the retinoblastoma locus in osteosarcomas. Diagn Mol Pathol 5: 214-219, 1996.
11. Tarkkanen M, Aaltonen LA, Böhling T, Kivioja A, Elomaa I and Knuutila S: No evidence of microsatellite instability in bone tumours. Br J Cancer 74: 453-455, 1996.
12. Enzinger FM and Weiss SW: Soft tissue tumours. 3rd edition. Mosby, St. Louis, Baltimore, 1995.
13. Mentzel T and Fletcher CDM: Lipomatous tumours of soft tissues: an update. Virchows Arch 427: 353-363, 1995.
14. Dei Tos AP, Doglioni C, Piccinin S, Maestro R, Mentzel T, Barbarcschi M, Boiocchi M and Fletcher CDM: Molecular abnormalities of the p53 pathway in dedifferentiated liposarcoma. J Pathol 181: 8-13, 1997.
15. Dei Tos AP, Piccinin S, Doglioni C, Vukosavljevic T, Mentzel T, Boiocchi M and Fletcher CD: Molecular aberrations of the G1-S checkpoint in myxoid and round cell liposarcoma. Am J Pathol 151: 1531-1539, 1997.
16. Pilotti S, Della Torre G, Lavarino C, Di Palma S, Sozzi G, Minoletti F, Rao S, Pasquini G, Azzarelli A, Rilke F and Pieroti MA: Distinct mdm2/p53 expression patterns in liposarcoma subgroups: implications for different pathogenetic mechanisms. J Pathol 191: 14-24, 1997.
17. Schneider-Stock R, Walter H, Rys J, Radig K and Roessner A: No correlation of c-myc overexpression and p53 mutations in liposarcomas. Virchows Arch 433: 315-321, 1998.
18. Schneider-Stock R, Walter H, Radig K, Rys J, Bosse A, Kuhnen C, Hoang-Vu C and Roessner A: MDM2 amplification and loss of heterozygosity at p53 and Rb: no simultaneous genetic events in the oncogenesis of liposarcomas. J Cancer Res Clin Oncol 124: 532-540, 1998.
19. Schneider-Stock R, Epplen JT, Walter H, Radig K, Rys J, Epplen C, Hoang-Vu C, Niezabitowski A and Roessner A: Telomeric lengths and telomerase activity in liposarcomas. Mol Carcinog (In press).
20. Schneider-Stock R, Rys J, Walter H, Limon J, Iliszko M and Roessner A: A rare chimeric TLS/FUS-CHOP transcript in a patient with multiple liposarcomas. J Cancer Genet Cytogenet (In press).
21. Trojani M, Contesso G, Coindre JM, Rouesse J, Bui NB, De Mascarle A, Goussot JF, David M, Bonichon F and Lagarde C: Soft tissue sarcomas of adults: study of pathological prognostic variables and definition of a histopathological grading system. Int J Cancer 33: 37-42, 1984.
22. Sambrook J, Fritsch EF and Maniatis T: Molecular cloning: a laboratory manual. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY, 1989.
23. Budowle B, Chakraboty R, Giusti AM, Eisenberg AJ and Allen RC: Analysis of the variable number of tanem repeats locus D1S80 by the polymerase chain reaction followed by high resolution polyacrylamide gel electrophoresis. Am J Hum Genet 48: 137-144, 1991.
24. Sachs L: Angewandte Statistik. 7th edition. Springer, Heidelberg, 1992.
25. Muller HJ and Scott RJ: Hereditary conditions in which the loss of heterozygosity may be important. Mutat Res 284: 15-24, 1992.
26. Knudson AG: Mutation and cancer: statistical study of retinoblastoma. Proc Natl Acad Sci USA 68: 820-823, 1971.
27. Li M, Zhang ZF, Reuter VE and Cordon-Cardo C: Chromosome 3 allelic losses and microsatellite alterations in transitional cell carcinoma of the urinary bladder. Am J Pathol 149: 229-235, 1996.
28. Johnson BE, Sakaguchi AY, Gazdar AF, Minna JD, Burch D, Angus M and Naylor SL: Restriction fragment length polymorphism studies show consistent loss of chromosome 3p alleles in small cell lung cancer patients' tumours. J Clin Invest 82: 502-507, 1988.
29. Chen LC, Matsumra K, Deng G, Kuriso W, Ljung BM, Lerman MI, Waldman FM and Smith HS: Deletion of two separate regions on chromosome 3p in breast cancers. Cancer Res 54: 3021-3024, 1994.
30. Toguchida J, Ishizaki K, Sasaki MS, Ikenaga M, Sugimoto M, Kotoura Y and Yamamuro T: Chromosomal reorganization for the expression of recessive mutation of retinoblastoma susceptibility gene in the development of osteosarcoma. Cancer Res 48: 3939-3943, 1988.
31. Dracopoli NC, Alhadeff B, Houghton AN and Old LJ: Loss of heterozygosity at autosomal and X-linked loci during tumour progression in a patient with melanoma. Cancer Res 47: 3995-4000, 1987.
32. Hurr K, Kemp B, Silver SA and El-Naggar AK: Microsatellite alteration at chromosome 3p loci in neurocndocrine and non-neuroendocrine lung tumours. Am J Pathol 149: 613-620, 1996.
33. Crozat A, Aman P, Mandahl N and Ron D: Fusion of CHOP to a novel RNA-binding protein in human myxoid liposarcoma. Nature 363: 640-644, 1993.
34. Sreekantaiah C, Ladanyi M, Rodriguez E and Chaganti RSK: Chromosomal aberrations in soft tissue tumours. Am J Pathol 144: 1121-1134, 1994.
35. Pabst T, Schwaller J, Bellomo MJ, Oestreicher M, Mühlematter D, Tichelli A, Tobler A and Fey MF: Frequent clonal loss of heterozygosity but scarcity of microsatellite instability at chromosomal breakpoint cluster regions in adult leukemias. Blood 88: 1026-1034, 1996.
36. Weissenbach J, Gyapay G, Dib C, Vignal A, Morisette J, Millasseau P and Vaysscix G: A second-generation linkage map of the human genome. Nature 359: 794-801, 1992.
37. Polymeropoulos MH, Rath DS, Xiao H and Merril CR: Tetranucleotide repeat polymorphism at the human c-fes/fps protoncogene (FES). Nucleic Acids Res 19: 4018, 1991.
38. Polymeropoulos MH, Xiao H, Rath DS and Merril CR: Tetranucleotide repeat polymorphism at the human tyrosine hydroxylase gene (TH). Nucleic Acids Res 19: 3753, 1991.
39. Möller A and Brinkmann B: Locus ACTBP2 (SE33). Sequencing data reveal considerable polymorphism. Int J Legal Med 106: 262-267, 1994.
40. Mills KA, Even D and Murray JC: Tetranucleotide repeat polymorphism at the human alpha fibrinogen locus (FGA). Hum Mol Genet 1: 779, 1992.
41. Kimpton CP, Walton A and Gill P: A urther tetranucleotide repeat polymorphism in the vWF gene. Hum Mol Genet 1: 28, 1992.
42. Chung DC and Rustgi AK: DNA mismatch repair and cancer. Gastoenterology 109: 1685-1699, 1995.