Cloning and expression of the Ca2+ channel α(1C) and β(2a) subunits from guinea pig heart

Journal of Biochemistry

Volumn 125, Issue 4, 1999, Pages 750-759

  Ding, Shan ^a,b   Kuroki, Sachiko ^a   Kameyama, Asako ^a   Yoshimura, Akihiko ^c   Kameyama, Masaki ^a  

^a KAGOSHIMA UNIVERSITY   (Japan)

^b KAGOSHIMA UNIVERSITY   (Japan)

^c KURUME UNIVERSITY   (Japan)

Author keywords

Ca2+ channel; Cloning; Guinea pig heart; (1C) sununit; 2 subunit

Indexed keywords

1,4 DIHYDRO 2,6 DIMETHYL 5 NITRO 4 [2 (TRIFLUOROMETHYL)PHENYL] 3 PYRIDINECARBOXYLIC ACID METHYL ESTER; BARIUM ION; CALCIUM CHANNEL; CALCIUM ION; COMPLEMENTARY DNA; FORSKOLIN; HEART ENZYME; MESSENGER RNA; NIFEDIPINE; OKADAIC ACID; VOLTAGE GATED CHANNEL FORMING PROTEIN; PRIMER DNA;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BRAIN; CALCIUM CURRENT; CEREBELLUM; CONTROLLED STUDY; DNA TRANSFECTION; ENZYME SUBUNIT; GENE EXPRESSION; GENE ISOLATION; GUINEA PIG; HEART; MOLECULAR CLONING; NONHUMAN; PATCH CLAMP; POLYMERASE CHAIN REACTION; RABBIT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SEQUENCE HOMOLOGY; STOMACH; TISSUE DISTRIBUTION; AMINO ACID SEQUENCE; ANIMAL; CELL LINE; CHEMISTRY; COMPARATIVE STUDY; GENETICS; HAMSTER; HEART MUSCLE; HUMAN; METABOLISM; MOLECULAR GENETICS; MOUSE; NUCLEOTIDE SEQUENCE; PROTEIN CONFORMATION; RAT; SPECIES DIFFERENCE;

ANIMALIA; CAVIA PORCELLUS; CRICETINAE; MAMMALIA; ORYCTOLAGUS CUNICULUS; SUS SCROFA;

AMINO ACID SEQUENCE; ANIMALS; BASE SEQUENCE; CALCIUM CHANNELS; CELL LINE; CLONING, MOLECULAR; CRICETINAE; DNA PRIMERS; DNA, COMPLEMENTARY; GENE EXPRESSION; GUINEA PIGS; HUMANS; MICE; MOLECULAR SEQUENCE DATA; MYOCARDIUM; PROTEIN CONFORMATION; RABBITS; RATS; SEQUENCE HOMOLOGY, AMINO ACID; SPECIES SPECIFICITY;

EID: 0033113113     PISSN: 0021924X     EISSN: None     Source Type: Journal    
DOI: 10.1093/oxfordjournals.jbchem.a022346     Document Type: Article

References (49)

1. Tanabe, T., Takeshima, H., Mikami, A., Flockerzi, V., Takahashi, H., Kangawa, K., Kojima, M., Matsuo, H., Hirose, T., and Numa, S. (1987) Primary structure of the receptor for calcium channel blockers from skeletal muscle. Nature 328, 313-318
2. Mikami, A., Imoto, K., Tanabe, T., Niidome, T., Mori, Y., Takeshima, H., Narumiya, S., and Numa, S. (1989) Primary structure and functional expression of the cardiac dihydropyridine-sensitive calcium channel. Nature 340, 230-233
3. Birnbaumer, L., Campbell, K.P., Catterall, W.A., Harpold, M., Hofmann, F., Horne, W.A., Mori, Y., Schwartz, A., Snutch, T.P., Tanabe, T., and Tsien, R.W. (1994) The naming of voltage-gated calcium channels. Neuron 13, 505-506
4. Perez-Reyes, E., Cribbs, L.L., Daud, A., Lacerda, A.E., Barcley, J., Williamson, M.P., Fox, M., Rees, M., and Lee, J-H. (1998) Molecular characterization of a neuronal low voltage-activated T-type calcium channel. Nature 391, 896-900
5. 2+ channel regulation by a conserved β subunit domain. Neuron 13, 495-503
6. Castellano, A., Wei, X., Birnbaumer, L., and Perez-Reyes, E. (1993) Cloning and expression of a neuronal calcium channel β subunit. J. Biol. Chem. 268, 12359-12366
7. 2+ channel diversity. Annu. Rev. Neurosci. 17, 399-418
8. Catterall, W.A. (1995) Structure and function of voltage-gated ion channels. Annu. Rev. Biochem. 64, 493-531
9. Mori, Y., Mikala, G., Varadi, G., Kobayashi, T., Koch, S., Wakamori, M., and Schwartz, A. (1996) Molecular pharmacology of voltage-dependent calcium channels. Jpn. J. Pharmacol. 72, 83-109
10. Kuniyasu, A., Oka, K., Ide-yamada, T., Hatanaka, Y., Abe, T., Nakayama, H., and Kanaoka, Y. (1992) Structural characterization of the dihydropyridine receptor-linked calcium channel from porcine heart. J. Biochem. 112, 235-242
11. Mitterdorfer, J., Wang, Z., Sinnegger, M.J., Hering, S., Strissning, J., Grabner, M., and Glossmann, H. (1996) Two amino acid residues in the IIIS5 segment of L-type calcium channels differentially contribute to 1,4-dihydropyridine sensitivity. J. Biol. Chem. 271, 30330-30335
12. Koch, W.J., Ellinor, P.T., and Schwartz, A. (1990) cDNA cloning of a dihydropyridine-sensitive calcium channel from rat aorta. J. Biol. Chem. 265, 17786-17791
13. Biel, M., Ruth, P., Bosse, E., Hullin, R., Stuhmer, W., Flockerzi, V., and Hofmann, F. (1990) Primary structure and functional expression of a high voltage activated calcium channel from rabbit lung. FEBS Lett. 269, 409-412
14. 2 and β subunits of novel human neuronal calcium channel subtype. Neuron 8, 71-84
15. Hullin, R., Singer-Lauhat, D., Freichel, M., Biel, M., Dascal, N., Hofmann, F., and Flockerzi, V. (1992) Calcium channel β subunit heterogeneity: functional expression of cloned cDNA from heart, aorta and brain. EMBO J. 11, 885-890
16. 1 subunit gene generates developmentally regulated isoforms in the rat heart. Proc. Natl. Acad. Sci. USA 89, 1497-1501
17. Perez-Reyes, E., Castellano, A., Kim, H.S., Bertrand, P., Baggstrom, E., Lacerda, A.E., Wei, X., and Birnbaumer, L. (1992) Cloning and expression of a cardiac/brain β subunit of the L-type calcium channel. J. Biol. Chem. 267, 1792-1797
18. Ma, W.J., Holz, R.W., and Uhler, M.D. (1992) Expression of cDNA for a neuronal calcium channel alpha 1 subunit enhances secretion from adrenal chromaffin cells. J. Biol. Chem. 267, 22728-22732
19. Graham, F.L. and Van der Eb, A.J. (1973) A new technique for the assay of infective of human adenovirus 5 DNA. Virology 52, 456-467
20. Gorman, C.M., Moffat, L.F., and Howard, B.H. (1982) Recombinant genomes which express chloramphenicol acetyltransferase in mammalian cells. Mol. Cell Biol. 2, 1044-1051
21. Sakmann, B. and Neher, E. (eds.) (1995) Single-Channel Recording (2nd ed), Plenum Press, New York
22. 1-subunit. Nature 368, 67-70
23. 2+ channels. Science 270, 1502-1526
24. 2+ channels. J. Biol. Chem. 270, 12056-12064
25. Hescheler, J., Mieskes, G., Ruegg, J.C., Takai, A., and Trautwein, W. (1988) Effects of a protein phosphatase inhibitor, okadaic acid, on membrane currents of isolated guinea-pig cardiac myocytes. Pflügers Arch. 412, 248-252
26. 1-adrenoceptors. Circ. Res. 76, 335-342
27. Hirano, Y., Yoshinaga, T., Niidome, T., Katayama, K., and Hiraoka, M. (1996) Modulation by dihydropyridines and protein kinases of the recombinant cardiac L-type Ca channel with multiple unitary current amplitudes. Receptors Channels 4, 93-104
28. 2+ channel. Trend. Pharm. Sci. 12, 349-354
29. 2+ channel. Genomics 22, 77-87
30. Singer, D., Biel, M., Lotan, I., Flockerzi, V., Hofmann, F., and Dascal, N. (1991) The roles of the subunits in the function of the calcium channel. Science 253, 1553-1557
31. Tomlinson, W.J., Stea, A., Bourinet, E., Charnet, P., Nargeot, J., and Snutch, T.P. (1993) Functional properties of a neuronal class C L-type calcium channel. Neuropharmacology 32, 1117-1126
32. 1 subunit and the effects of a cardiac β subunit. Biochem. Biophys. Res. Commun. 196, 1170-1176
33. Ferreira, G., Yi, J., Ríos, E., and Shirokov, R. (1997) Ion-dependent inactivation of barium current through L-type calcium channels. J. Gen. Physiol. 109, 449-461
34. Olcese, R., Qin, N., Schneider, T., Neely, A., Wei, X., Stefani, E., and Birnbaumer, L. (1994) The amino terminus of a calcium channel β subunit sets rates of channel inactivation independently of the subunit's effect on activation. Neuron 13, 1433-1438
35. Zhang, J., Ellinor, P.T., Aldrich, R.W., and Tsien, R.W. (1994) Molecular determinants of voltage-dependent inactivation in calcium channels. Nature 372, 97-100
36. 2+ dependence of inactivation. J. Biol. Chem. 272, 3560-3566
37. 2+ channels: role in channel function. Trends Neurosci. 21, 148-154
38. 2+-binding domains. Proc. Natl. Acad. Sci. USA 94, 2301-2305
39. Charnet, P., Lory, P., Bourinet, E., Collin, T., and Nargeot, J. (1995) cAMP-dependent phosphorylation of the cardiac L-type Ca channel: A missing link? Biochimie 77, 957-962
40. Singer-Lahat, D., Lotan, I., Biel, M., Flockerzi, V., Hofmann, F., and Dascal, N. (1994) Cardiac calcium channels expressed in Xenopus oocytes are modulated by dephosphorylation, but not by cAMP-dependent phosphorylation. Receptors Channels 2, 215-226
41. 1 subunit. J. Biol. Chem. 268, 19451-19457
42. John, H., Nastainczyk, W., Rohrkasten, A., Schneider, T., and Hofmann, F. (1988) Site-specific phosphorylation of the purified receptor for calcium-channel blockers by cAMP- and cGMP-dependent protein kinase, protein kinase C, calmodulin-dependent protein kinase II and casein kinase II. Eur. J. Biochem. 178, 535-542
43. 1 subunit of the cardiac L-type calcium channel by adenosine 3′,5′-cyclic monophosphate dependent protein kinase. Biochemistry 35, 10392-10402
44. Puri, T.S., Gerhardstein, B.L., Zhao, X-L., Ladner, M.B., and Hosey, M.M. (1997) Differential effects of subunit interaction on protein kinase A- and C-mediated phosphorylation of L-type calcium channels. Biochemistry 36, 9605-9615
45. 2+ channels requires membrane targeting of PKA and phosphorylation of channel subunits. Neuron 19, 185-196
46. 1c subunit. FEBS Lett. 384, 189-192
47. 1 subunits. Biochemistry 35, 9400-9406
48. 1 subunit. Biochim. Biophys. Acta 1281, 205-212
49. 2+ channel affecting different kinetic functions. J. Physiol. 470, 73-84