-
1
-
-
0028708677
-
Paclitaxel (Taxoi): Mechanism of action
-
Horwitz SB. Paclitaxel (Taxoi): mechanism of action. Ann Oncol 1994; 5 (suppl. 6): S3-6.
-
(1994)
Ann Oncol
, vol.5
, Issue.6 SUPPL.
-
-
Horwitz, S.B.1
-
2
-
-
0002291316
-
Topoisomerase inliibitors
-
Chabner BA, Longo LA, eds. Philadelphia: Uppincott-Raven
-
Pommier Y, Fesan MR, Goldwasser F. Topoisomerase inliibitors. In: Chabner BA, Longo LA, eds. Cancer chemotherapy and biotberapy, 2nd edn. Philadelphia: Uppincott-Raven 1996: 435-61.
-
(1996)
Cancer Chemotherapy and Biotberapy, 2nd Edn
, pp. 435-461
-
-
Pommier, Y.1
Fesan, M.R.2
Goldwasser, F.3
-
3
-
-
0029827435
-
Analysis of eukaroytic DNA topoisomerase and topoisomerase-directed drug effects
-
Boege F. Analysis of eukaroytic DNA topoisomerase and topoisomerase-directed drug effects. Eur J Clin Chem Biochem 1996; 34: 873-88.
-
(1996)
Eur J Clin Chem Biochem
, vol.34
, pp. 873-888
-
-
Boege, F.1
-
4
-
-
0028012558
-
A rapid mechanism-based screen to detect potential anti-cancer agents
-
Swaffar DS, Ireland CM, Barrows LR. A rapid mechanism-based screen to detect potential anti-cancer agents. Anti-Cancer Drugs 1994; 5: 15-23.
-
(1994)
Anti-Cancer Drugs
, vol.5
, pp. 15-23
-
-
Swaffar, D.S.1
Ireland, C.M.2
Barrows, L.R.3
-
5
-
-
0021063154
-
X-ray sensitive mutants of CHO cells defective in double strand break rejoining
-
Jeggo PA, Sedgwick SG, Kemp LM. X-ray sensitive mutants of CHO cells defective in double strand break rejoining. Mutât Res 1983; 112: 313-27.
-
(1983)
Mutât Res
, vol.112
, pp. 313-327
-
-
Jeggo, P.A.1
Sedgwick, S.G.2
Kemp, L.M.3
-
7
-
-
0024804442
-
Sensitivity of Chinese hamster ovary mutants defective in DNA double strand break repair to topoisomerase II inhibitors
-
Jeggo PA, Caldecott K, Pidsley S, Banks GR. Sensitivity of Chinese hamster ovary mutants defective in DNA double strand break repair to topoisomerase II inhibitors. Cancer Res 1989; 49: 7057-63.
-
(1989)
Cancer Res
, vol.49
, pp. 7057-7063
-
-
Jeggo, P.A.1
Caldecott, K.2
Pidsley, S.3
Banks, G.R.4
-
8
-
-
0025975313
-
Topoisomerase n activity in a DNA double strand repair deficient Chinese hamster ovary cell line
-
Warters RL, Lyons BW, U TM. Topoisomerase n activity in a DNA double strand repair deficient Chinese hamster ovary cell line. Mutât Res 1991; 254: 167-74.
-
(1991)
Mutât Res
, vol.254
, pp. 167-174
-
-
Warters, R.L.1
Lyons, B.W.2
Tm, U.3
-
9
-
-
0030591651
-
DNA damage and mutagenesis by radiomimetic DNA-cleaving agents: Bleomycin, neocarzinostatin and other enediynes
-
Povirk LF. DNA damage and mutagenesis by radiomimetic DNA-cleaving agents: bleomycin, neocarzinostatin and other enediynes. Mutât Res 1996; 355: 71-89.
-
(1996)
Mutât Res
, vol.355
, pp. 71-89
-
-
Povirk, L.F.1
-
10
-
-
0027366526
-
Makaluvamines, marine natural products, are active anticancer agents and DNA topo II inhibitors
-
Barrows LR, Radisky DC, Swaffar DS, Copp BR, et al. Makaluvamines, marine natural products, are active anticancer agents and DNA topo II inhibitors. AntiCancer Drug Des 1993; 8: 333-47.
-
(1993)
AntiCancer Drug Des
, vol.8
, pp. 333-347
-
-
Barrows, L.R.1
Radisky, D.C.2
Swaffar, D.S.3
Copp, B.R.4
-
11
-
-
0027156278
-
Impairment of V(D)J recombination in double-strand break repair mutants
-
Taccioli GE, Rathbun G, Oltz E, Stamato T, et al. Impairment of V(D)J recombination in double-strand break repair mutants. Science 1993; 260: 207-10.
-
(1993)
Science
, vol.260
, pp. 207-210
-
-
Taccioli, G.E.1
Rathbun, G.2
Oltz, E.3
Stamato, T.4
-
12
-
-
0021099884
-
DNA topoisomerase n from Drosophila melanogaster. relaxation of supercoiled
-
Osheroff N, Shelton ER, Brutlag DL DNA topoisomerase n from Drosophila melanogaster. relaxation of supercoiled DNA-JBtoICbein 1983; 258: 9536-43.
-
(1983)
DNA-JBtoICbein
, vol.258
, pp. 9536-9543
-
-
Osheroff, N.1
Shelton, E.R.2
Brutlag, D.L.3
-
13
-
-
0024594222
-
Modulation of topoisomerase II catalytic activity by DNA minor groove binding agents distamycin, Hoeclist 33258 and 4′,6-diamidine-2-phenyiindoIe
-
Woynarowski JM, McHugh M, Sigmund RD, Beerman TA. Modulation of topoisomerase II catalytic activity by DNA minor groove binding agents distamycin, Hoeclist 33258 and 4′,6-diamidine-2-phenyiindoIe. Mol Phannacol 1989; 35: 177-82.
-
(1989)
Mol Phannacol
, vol.35
, pp. 177-182
-
-
Woynarowski, J.M.1
McHugh, M.2
Sigmund, R.D.3
Beerman, T.A.4
-
14
-
-
0024314258
-
Mammalian topoisomerase II activity is modulated by the DNA minor groove binder distamycin in simian virus 40 DNA
-
Fesan Al, Pommier Y. Mammalian topoisomerase II activity is modulated by the DNA minor groove binder distamycin in simian virus 40 DNA. J Biol Cbem 1989; 264: 11354-9.
-
(1989)
J Biol Cbem
, vol.264
, pp. 11354-11359
-
-
Al, F.1
Pommier, Y.2
-
15
-
-
0026425619
-
Inhibition of topoisomerase II by antitumor agents bis(2,6-dioxopiperazine) derivatives
-
Tanabe K, Ikegami Y, Ishida R, Andoh T. Inhibition of topoisomerase II by antitumor agents bis(2,6-dioxopiperazine) derivatives. Cancer Res 1991; 51: 4903-8.
-
(1991)
Cancer Res
, vol.51
, pp. 4903-4908
-
-
Tanabe, K.1
Ikegami, Y.2
Ishida, R.3
Andoh, T.4
-
16
-
-
0019364861
-
DNA modification and cancer
-
Waring MJ. DNA modification and cancer. Annu Rev Biochem 1981; 50: 159-92.
-
(1981)
Annu Rev Biochem
, vol.50
, pp. 159-192
-
-
Waring, M.J.1
-
17
-
-
0027065109
-
Alode of action of topoisomerase II-targeting agents at a specific DNA sequence. Uncoupling the DNA cleavage and religation events
-
Sorensen BS, Sinding J, Anderson AH, Alsner J, et al. Alode of action of topoisomerase II-targeting agents at a specific DNA sequence. Uncoupling the DNA cleavage and religation events. J Mol Biol 1992; 228: 778-86.
-
(1992)
J Mol Biol
, vol.228
, pp. 778-786
-
-
Sorensen, B.S.1
Sinding, J.2
Anderson, A.H.3
Alsner, J.4
-
18
-
-
0029015354
-
Topoisomerase II binds to ellipticine in the absence or presence of DNA
-
149985004.
-
Froelich-Ammon SJ, Patchan A1W, Osheroff N, Thompson RB. Topoisomerase II binds to ellipticine in the absence or presence of DNA. J Biol Cbem 1995, 270: 149985004.
-
(1995)
J Biol Cbem
, vol.270
-
-
Froelich-Ammon, S.J.1
Aw, P.2
Osheroff, N.3
Thompson, R.B.4
-
19
-
-
0028345406
-
Antitumor bisdioxopiperazines inhibit yeast DNA topoisomerase II by trapping the enzyme in the form of a closed protein clamp
-
Roca J, Isliida R, Berger JM, Andoh T, et al. Antitumor bisdioxopiperazines inhibit yeast DNA topoisomerase II by trapping the enzyme in the form of a closed protein clamp. Proc Natl Acad Set USA 1994; 91: 1781-5.
-
(1994)
Proc Natl Acad Set USA
, vol.91
, pp. 1781-1785
-
-
Roca, J.1
Isliida, R.2
Berger, J.M.3
Andoh, T.4
-
20
-
-
0029802613
-
Topoisomerase II-etoposide interactions direct the formation of drug induced enzyme-cleavage complexes
-
Burdan DA, Kingma PS, Froelich-Ammon SJ, Thompson RB, et al. Topoisomerase II-etoposide interactions direct the formation of drug induced enzyme-cleavage complexes. J Biol Cbem 1996; 271: 29238-44.
-
(1996)
J Biol Cbem
, vol.271
, pp. 29238-29244
-
-
Burdan, D.A.1
Kingma, P.S.2
Froelich-Ammon, S.J.3
Thompson, R.B.4
-
21
-
-
0032554863
-
Antitumor agents. 185. Synthesis and biological evaluation of tridemethylthiocolchicine analogs as novel topoisomerase II inhibitors
-
Guan J, Zhu XK, Tacliibana Y, Bastow KF, et al. Antitumor agents. 185. Synthesis and biological evaluation of tridemethylthiocolchicine analogs as novel topoisomerase II inhibitors. J Med Cbem 1998; 41: 1956-61.
-
(1998)
J Med Cbem
, vol.41
, pp. 1956-1961
-
-
Guan, J.1
Zhu, X.K.2
Tacliibana, Y.3
Bastow, K.F.4
-
22
-
-
0026425654
-
Inhibition of intracellular topoisomerase II by amitumor bis(2,6doxopiperazine) derivatives: Mode of cell growth inhibition distinct from that of cleavable complex-forming type inhibitors
-
Ishida R, Tetsuo M, Narita T, Yui R, et al. Inhibition of intracellular topoisomerase II by amitumor bis(2,6doxopiperazine) derivatives: mode of cell growth inhibition distinct from that of cleavable complex-forming type inhibitors. Cancer Res 1991; 51: 4909-16.
-
(1991)
Cancer Res
, vol.51
, pp. 4909-4916
-
-
Ishida, R.1
Tetsuo, M.2
Narita, T.3
Yui, R.4
-
23
-
-
0027965136
-
Defining functional drug-interaction domains on topoisomerase II by exploiting mechanistic differences between drug classes
-
Osheroff N, Corbett AH, Hsea SH, Westergaard M. Defining functional drug-interaction domains on topoisomerase II by exploiting mechanistic differences between drug classes. Cancer Cbemotber Pbannacol 1994; 34: S19-25.
-
(1994)
Cancer Cbemotber Pbannacol
, vol.34
-
-
Osheroff, N.1
Corbett, A.H.2
Hsea, S.H.3
Westergaard, M.4
-
24
-
-
0021959397
-
Purification and characterization of a type II DNA topoisomerase from bovine calf thymus
-
Halligan BD, Edwards KA, Liu LF. Purification and characterization of a type II DNA topoisomerase from bovine calf thymus.J Biol Cbem 1985; 260: 2475-82.
-
(1985)
J Biol Cbem
, vol.260
, pp. 2475-2482
-
-
Halligan, B.D.1
Edwards, K.A.2
Liu, L.F.3
-
25
-
-
0002576411
-
Antimicrotubule agents
-
Chabner BA, Longo DL, eds. Pliiladelpliia: Lippincott-Raven
-
Rowinsky EK, Donehower RC. Antimicrotubule agents. In: Chabner BA, Longo DL, eds. Cancer chemotherapy and biothcrapy, 2nd edn. Pliiladelpliia: Lippincott-Raven 1996: 263-96.
-
(1996)
Cancer Chemotherapy and Biothcrapy, 2nd Edn
, pp. 263-296
-
-
Rowinsky, E.K.1
Donehower, R.C.2
-
26
-
-
0030020158
-
Mitotic block induced in HeLa cells by low concentrations of paclitaxel (Taxol) results in abnormal mitotic exit and apoptotic cell death
-
Jordan MA, Wendall K, Gardiner S, Wilson L, et al. Mitotic block induced in HeLa cells by low concentrations of paclitaxel (Taxol) results in abnormal mitotic exit and apoptotic cell death. Cancer Res 1996; 56: 816-25.
-
(1996)
Cancer Res
, vol.56
, pp. 816-825
-
-
Jordan, M.A.1
Wendall, K.2
Gardiner, S.3
Wilson, L.4
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