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Volumn 59, Issue 5, 1999, Pages 1096-1101

G-protein γ 7 is down-regulated in cancers and associated with P 27(kip1)-induced growth arrest

Author keywords

[No Author keywords available]

Indexed keywords

GUANINE NUCLEOTIDE BINDING PROTEIN; PROTEIN P27;

EID: 0033106052     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (40)

References (47)
  • 1
    • 0028011112 scopus 로고
    • Proteins: Critical control points for transmembrane signals
    • Neer, E. J. G proteins: critical control points for transmembrane signals. Protein Sci., 3: 3-14, 1994.
    • (1994) Protein Sci. , vol.3 , pp. 3-14
    • Neer, E.J.G.1
  • 2
    • 0029145416 scopus 로고
    • Structural and functional relationships of heterotrimeric G-proteins
    • Rens, D. S., and Hamm, H. E. Structural and functional relationships of heterotrimeric G-proteins. FASEB J., 9: 1059-1066, 1995.
    • (1995) FASEB J. , vol.9 , pp. 1059-1066
    • Rens, D.S.1    Hamm, H.E.2
  • 3
    • 0030600131 scopus 로고    scopus 로고
    • Potential roles of heterotrimeric G proteins of the endomembrane system
    • Nurnberg, B., and Ahnert, H. G. Potential roles of heterotrimeric G proteins of the endomembrane system. Febs Lett., 389: 61-65, 1996.
    • (1996) Febs Lett. , vol.389 , pp. 61-65
    • Nurnberg, B.1    Ahnert, H.G.2
  • 4
    • 0030938936 scopus 로고    scopus 로고
    • G-protein-coupled receptors: Molecular mechanisms involved in receptor activation and selectivity of G-protein recognition
    • Wess, J. G-protein-coupled receptors: molecular mechanisms involved in receptor activation and selectivity of G-protein recognition. FASEB J., 11: 346-354, 1997.
    • (1997) FASEB J. , vol.11 , pp. 346-354
    • Wess, J.1
  • 5
    • 0027715737 scopus 로고
    • Conditional regulation of adenylyl cyclases by G- Protein βγ-subunits
    • Ueda, N., and Tang, W. J. Conditional regulation of adenylyl cyclases by G- protein βγ-subunits. Biochem. Soc. Trans., 21: 1132-1138, 1993.
    • (1993) Biochem. Soc. Trans. , vol.21 , pp. 1132-1138
    • Ueda, N.1    Tang, W.J.2
  • 6
    • 0027495684 scopus 로고
    • New roles for G-protein βγ-dimers in transmembrane signaling
    • Clapham, D. E., and Neer, E. J. New roles for G-protein βγ-dimers in transmembrane signaling. Nature (Lond.), 365: 403-406, 1993.
    • (1993) Nature (Lond.) , vol.365 , pp. 403-406
    • Clapham, D.E.1    Neer, E.J.2
  • 7
    • 0028912416 scopus 로고
    • The role of G-protein βγ subunits in signal transduction
    • Muller, S., and Lohse, M. J. The role of G-protein βγ subunits in signal transduction. Biochem. Soc. Trans., 23: 141-148, 1995.
    • (1995) Biochem. Soc. Trans. , vol.23 , pp. 141-148
    • Muller, S.1    Lohse, M.J.2
  • 8
    • 0029961869 scopus 로고    scopus 로고
    • Oncogenic role of heterotrimeric G proteins
    • Vallar, L. Oncogenic role of heterotrimeric G proteins. Cancer Surv., 27: 325-338, 1996.
    • (1996) Cancer Surv. , vol.27 , pp. 325-338
    • Vallar, L.1
  • 9
    • 0024376173 scopus 로고
    • Ras oncogenes in human cancer
    • Bos, J. L. ras oncogenes in human cancer. Cancer Res., 49: 4682-4689, 1989.
    • (1989) Cancer Res. , vol.49 , pp. 4682-4689
    • Bos, J.L.1
  • 10
    • 0028808638 scopus 로고
    • The Rac and Rho pathways as a source of drug targets for Ras-mediated malignancies
    • Symons, M. The Rac and Rho pathways as a source of drug targets for Ras-mediated malignancies. Curr. Opin. Biotechnol., 6: 668-674, 1995.
    • (1995) Curr. Opin. Biotechnol. , vol.6 , pp. 668-674
    • Symons, M.1
  • 11
    • 0030455117 scopus 로고    scopus 로고
    • Regulation of cytoskeletal functions by Rho small GTP-binding proteins in normal and cancer cells
    • Boivin, D., Bilodeau, D., and Beliveau, R. Regulation of cytoskeletal functions by Rho small GTP-binding proteins in normal and cancer cells. Can. J. Physiol. Pharmacol., 74: 801-810, 1996.
    • (1996) Can. J. Physiol. Pharmacol. , vol.74 , pp. 801-810
    • Boivin, D.1    Bilodeau, D.2    Beliveau, R.3
  • 12
    • 0032496048 scopus 로고    scopus 로고
    • Identification and cloning of human G-protein γ 7, down-regulated in pancreatic cancer
    • Shibata, K., Mori, M., Tanaka, S., Kitano, S., and Akiyoshi, T. Identification and cloning of human G-protein γ 7, down-regulated in pancreatic cancer. Biochem. Biophys. Res. Commun., 246: 205-209, 1998.
    • (1998) Biochem. Biophys. Res. Commun. , vol.246 , pp. 205-209
    • Shibata, K.1    Mori, M.2    Tanaka, S.3    Kitano, S.4    Akiyoshi, T.5
  • 13
    • 0027332053 scopus 로고
    • Specific enhancement of β-adrenergic receptor kinase activity by defined G-protein β and γ subunits
    • Muller, S., Hekman, M., and Lohse, M. J. Specific enhancement of β-adrenergic receptor kinase activity by defined G-protein β and γ subunits. Proc. Natl. Acad. Sci. USA, 90: 10439-10443, 1993.
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 10439-10443
    • Muller, S.1    Hekman, M.2    Lohse, M.J.3
  • 14
    • 0028933055 scopus 로고
    • Identification of a discrete region of the G protein γ subunit conferring selectivity in βγ complex formation
    • Lee, C., Murakami, T., and Simonds, W. F. Identification of a discrete region of the G protein γ subunit conferring selectivity in βγ complex formation. J. Biol. Chem., 270: 8779-8784, 1995.
    • (1995) J. Biol. Chem. , vol.270 , pp. 8779-8784
    • Lee, C.1    Murakami, T.2    Simonds, W.F.3
  • 15
    • 0025090885 scopus 로고
    • Carboxyl methylation and COOH-terminal processing of the brain G-protein γ-subunit
    • Backlund, P. J., Simonds, W. F., and Spiegel, A. M. Carboxyl methylation and COOH-terminal processing of the brain G-protein γ-subunit. J. Biol. Chem., 265: 15572-15576, 1990.
    • (1990) J. Biol. Chem. , vol.265 , pp. 15572-15576
    • Backlund, P.J.1    Simonds, W.F.2    Spiegel, A.M.3
  • 16
    • 0025649688 scopus 로고
    • Posttranslational modification of proteins by isoprenoids in mammalian cells
    • Maltese, W. A. Posttranslational modification of proteins by isoprenoids in mammalian cells (Review: 66 refs.). FASEB J., 4: 3319-3328, 1990.
    • (1990) FASEB J. , vol.4 , pp. 3319-3328
    • Maltese, W.A.1
  • 17
    • 0026049664 scopus 로고
    • Polyisoprenylation of the CAAX motif: An in vitro protein synthesis study
    • Newman, P., Kube, E., Gerke, V., and Weber, K. Polyisoprenylation of the CAAX motif: an in vitro protein synthesis study. Biochim. Biophys. Acta, 1080: 227-230, 1991.
    • (1991) Biochim. Biophys. Acta , vol.1080 , pp. 227-230
    • Newman, P.1    Kube, E.2    Gerke, V.3    Weber, K.4
  • 18
    • 0026009360 scopus 로고
    • G-protein βγ dimers. Membrane targeting requires subunit coexpression and intact γ C-A-A-X domain
    • Simonds, W. F., Butrynski, J. E., Gautam, N., Unson, C. G., and Spiegel, A. M. G-protein βγ dimers. Membrane targeting requires subunit coexpression and intact γ C-A-A-X domain. J. Biol. Chem., 266: 5363-5366, 1991.
    • (1991) J. Biol. Chem. , vol.266 , pp. 5363-5366
    • Simonds, W.F.1    Butrynski, J.E.2    Gautam, N.3    Unson, C.G.4    Spiegel, A.M.5
  • 19
    • 0028808638 scopus 로고
    • The Rac and Rho pathways as a source of drug targets for Ras-mediated malignancies
    • Symons, M. The Rac and Rho pathways as a source of drug targets for Ras-mediated malignancies (Review: 63 refs.). Curr Opin. Biotech., 6: 668-674, 1995.
    • (1995) Curr Opin. Biotech. , vol.6 , pp. 668-674
    • Symons, M.1
  • 20
    • 0027056925 scopus 로고
    • Selective tissue distribution of G protein γ subunits, including a new form of the γ subunits identified by cDNA cloning
    • Cali, J. J., Balcueva, E. A., Rybalkin, I., and Robishaw, J. D. Selective tissue distribution of G protein γ subunits, including a new form of the γ subunits identified by cDNA cloning. J. Biol. Chem., 267: 24023-24027, 1992.
    • (1992) J. Biol. Chem. , vol.267 , pp. 24023-24027
    • Cali, J.J.1    Balcueva, E.A.2    Rybalkin, I.3    Robishaw, J.D.4
  • 21
    • 0029099297 scopus 로고
    • Isolation of cDNA clones encoding eight different human G protein γ subunits, including three novel forms designated the γ 4, γ 10, and γ 11 subunits
    • Ray, K., Kunsch, C., Bonner, L. M., and Robishaw, J. D. Isolation of cDNA clones encoding eight different human G protein γ subunits, including three novel forms designated the γ 4, γ 10, and γ 11 subunits. J. Biol. Chem., 270: 21765-21771, 1995.
    • (1995) J. Biol. Chem. , vol.270 , pp. 21765-21771
    • Ray, K.1    Kunsch, C.2    Bonner, L.M.3    Robishaw, J.D.4
  • 22
    • 0028342664 scopus 로고
    • Cloning of senescent cell-derived inhibitors of DNA synthesis using an expression screen
    • Noda, A., Ning, Y., Venable, S. F., Pereira, S. O., and Smith, J. R. Cloning of senescent cell-derived inhibitors of DNA synthesis using an expression screen. Exp. Cell Res., 211: 90-98, 1994.
    • (1994) Exp. Cell Res. , vol.211 , pp. 90-98
    • Noda, A.1    Ning, Y.2    Venable, S.F.3    Pereira, S.O.4    Smith, J.R.5
  • 23
    • 0028179669 scopus 로고
    • p27Kip1, a cyclin-Cdk inhibitor, links transforming growth factor-β and contact inhibition to cell cycle arrest
    • Polyak, K., Kato, J. Y., Solomon, M. J., Sherr, C. J., Massague, J., Roberts, J. M., and Koff, A. p27Kip1, a cyclin-Cdk inhibitor, links transforming growth factor-β and contact inhibition to cell cycle arrest. Genes Dev., 8: 9-22, 1994.
    • (1994) Genes Dev. , vol.8 , pp. 9-22
    • Polyak, K.1    Kato, J.Y.2    Solomon, M.J.3    Sherr, C.J.4    Massague, J.5    Roberts, J.M.6    Koff, A.7
  • 24
    • 0027172019 scopus 로고
    • Prothymosin-α mRNA expression correlates with that of c-myc in human colon cancer
    • Mori, M., Barnard, G. F., Staniunas, R. J., Jessup, J. M., Steele, G. J., and Chen, L. B. Prothymosin-α mRNA expression correlates with that of c-myc in human colon cancer. Oncogene, 8: 2821-2826, 1993.
    • (1993) Oncogene , vol.8 , pp. 2821-2826
    • Mori, M.1    Barnard, G.F.2    Staniunas, R.J.3    Jessup, J.M.4    Steele, G.J.5    Chen, L.B.6
  • 26
    • 0029100684 scopus 로고
    • Detection of cancer micrometastases in lymph nodes by reverse transcriptase-polymerase chain reaction
    • Mori, M., Mimori, K., Inoue, H., Barnard, G. F., Tsuji, K., Nanbara, S., Ueo, H., and Akiyoshi, T. Detection of cancer micrometastases in lymph nodes by reverse transcriptase-polymerase chain reaction. Cancer Res., 55: 3417-3420, 1995.
    • (1995) Cancer Res. , vol.55 , pp. 3417-3420
    • Mori, M.1    Mimori, K.2    Inoue, H.3    Barnard, G.F.4    Tsuji, K.5    Nanbara, S.6    Ueo, H.7    Akiyoshi, T.8
  • 27
    • 0030483317 scopus 로고    scopus 로고
    • Molecular detection of circulating solid carcinoma cells in the peripheral blood: The concept of early systemic disease
    • Mori, M., Mimori, K., Ueo, H., Karimine, N., Barnard, G. F., Sugimachi, K., and Akiyoshi, T. Molecular detection of circulating solid carcinoma cells in the peripheral blood: the concept of early systemic disease. Int. J. Cancer, 68: 739-743, 1996.
    • (1996) Int. J. Cancer , vol.68 , pp. 739-743
    • Mori, M.1    Mimori, K.2    Ueo, H.3    Karimine, N.4    Barnard, G.F.5    Sugimachi, K.6    Akiyoshi, T.7
  • 29
    • 0024676037 scopus 로고
    • Yeast pheromone response pathway: Characterization of a suppressor that restores mating to receptorless mutants
    • Clark, K. L., and Sprague, G. J. Yeast pheromone response pathway: characterization of a suppressor that restores mating to receptorless mutants. Mol. Cell. Biol., 9: 2682-2694, 1989.
    • (1989) Mol. Cell. Biol. , vol.9 , pp. 2682-2694
    • Clark, K.L.1    Sprague, G.J.2
  • 30
    • 0024526152 scopus 로고
    • The yeast G-protein homolog is involved in the mating pheromone signal transduction system
    • Fujimura, H. A. The yeast G-protein homolog is involved in the mating pheromone signal transduction system. Mol. Cell. Biol., 9: 152-158, 1989.
    • (1989) Mol. Cell. Biol. , vol.9 , pp. 152-158
    • Fujimura, H.A.1
  • 31
    • 0025159301 scopus 로고
    • Regulation of the yeast pheromone response pathway by G protein subunits
    • Nomoto, S., Nakayama, N., Arai, K., and Matsumoto, K. Regulation of the yeast pheromone response pathway by G protein subunits. EMBO J., 9: 691-696, 1990.
    • (1990) EMBO J. , vol.9 , pp. 691-696
    • Nomoto, S.1    Nakayama, N.2    Arai, K.3    Matsumoto, K.4
  • 32
    • 0027191189 scopus 로고
    • Far 1 links the signal transduction pathway to the cell cycle machinery in yeast
    • Peter, M.. Gartner, A., Horecka, J., Ammerer, G. and Herskowitz, I. Far 1 links the signal transduction pathway to the cell cycle machinery in yeast. Cell, 73: 747-760, 1993.
    • (1993) Cell , vol.73 , pp. 747-760
    • Peter, M.1    Gartner, A.2    Horecka, J.3    Ammerer, G.4    Herskowitz, I.5
  • 33
    • 0024966029 scopus 로고
    • The STE4 and STE18 genes of yeast encode potential β and γ subunits of the mating factor receptor-coupled G protein
    • Whiteway, M., Hougan, L., Dignard, D., Thomas, D. Y., Bell, L., Saari, G. C., Grant, F. J., O'Hara, P., and MacKay, V. L. The STE4 and STE18 genes of yeast encode potential β and γ subunits of the mating factor receptor-coupled G protein. Cell 56: 467-477, 1989.
    • (1989) Cell , vol.56 , pp. 467-477
    • Whiteway, M.1    Hougan, L.2    Dignard, D.3    Thomas, D.Y.4    Bell, L.5    Saari, G.C.6    Grant, F.J.7    O'Hara, P.8    MacKay, V.L.9
  • 34
    • 0029960339 scopus 로고    scopus 로고
    • Genetic relationships between the G protein β γ complex, Ste5p, Ste20p and Cdc42p: Investigation of effector roles in the yeast pheromone response pathway
    • Akada, R., Kallal, L., Johnson, D. I., and Kurjan, J. Genetic relationships between the G protein β γ complex, Ste5p, Ste20p and Cdc42p: investigation of effector roles in the yeast pheromone response pathway. Genetics, 143: 103-117, 1996.
    • (1996) Genetics , vol.143 , pp. 103-117
    • Akada, R.1    Kallal, L.2    Johnson, D.I.3    Kurjan, J.4
  • 35
    • 0025191033 scopus 로고
    • Overexpression of the STE4 gene leads to mating response in haploid Saccharomyces cerevisiae
    • Whiteway, M., Hougan, L., and Thomas, D. Y. Overexpression of the STE4 gene leads to mating response in haploid Saccharomyces cerevisiae. Mol. Cell. Biol., 10: 217-222, 1990.
    • (1990) Mol. Cell. Biol. , vol.10 , pp. 217-222
    • Whiteway, M.1    Hougan, L.2    Thomas, D.Y.3
  • 36
    • 0024966005 scopus 로고
    • Constitutive mutants in the yeast pheromone response: Ordered function of the gene products
    • Blinder, D., Bouvier, S., and Jenness, D. D. Constitutive mutants in the yeast pheromone response: ordered function of the gene products. Cell, 56: 479-486, 1989.
    • (1989) Cell , vol.56 , pp. 479-486
    • Blinder, D.1    Bouvier, S.2    Jenness, D.D.3
  • 37
    • 0026934115 scopus 로고
    • Mutagenesis of Ste18, a putative G y subunit in the Saccharomyces cerevisiae pheromone response pathway
    • Whiteway, M., Dignard, D., and Thomas, D. Y. Mutagenesis of Ste18, a putative G y subunit in the Saccharomyces cerevisiae pheromone response pathway. Biochem. Cell Biol., 70: 1230-1237, 1992.
    • (1992) Biochem. Cell Biol. , vol.70 , pp. 1230-1237
    • Whiteway, M.1    Dignard, D.2    Thomas, D.Y.3
  • 38
    • 0028284596 scopus 로고
    • Biochemical and genetic analysis of dominant-negative mutations affecting a yeast G-protein γ subunit
    • Grishin, A. V., Weiner, J. L., and Blumer, K. J. Biochemical and genetic analysis of dominant-negative mutations affecting a yeast G-protein γ subunit. Mol. Cell. Biol. 14: 4571-4578, 1994.
    • (1994) Mol. Cell. Biol. , vol.14 , pp. 4571-4578
    • Grishin, A.V.1    Weiner, J.L.2    Blumer, K.J.3
  • 39
    • 0028065397 scopus 로고
    • Site-directed mutations altering the CAAX box of Ste18, the yeast pheromone-response pathway G γ subunit
    • Whiteway, M. S., and Thomas, D. Y. Site-directed mutations altering the CAAX box of Ste18, the yeast pheromone-response pathway G γ subunit. Genetics, 137: 967-976, 1994.
    • (1994) Genetics , vol.137 , pp. 967-976
    • Whiteway, M.S.1    Thomas, D.Y.2
  • 40
    • 0031048236 scopus 로고    scopus 로고
    • Increased proteasome-dependent degradation of the cyclin-dependent kinase inhibitor p27 in aggressive colorectal carcinomas
    • Loda, M., Cukor, B., Tam, S. W., Lavin, P., Fiorentino, M., Draetta, G. F., Jessup, J. M., and Pagano, M. Increased proteasome-dependent degradation of the cyclin-dependent kinase inhibitor p27 in aggressive colorectal carcinomas (see comments). Nat. Med. 3: 231-234, 1997.
    • (1997) Nat. Med. , vol.3 , pp. 231-234
    • Loda, M.1    Cukor, B.2    Tam, S.W.3    Lavin, P.4    Fiorentino, M.5    Draetta, G.F.6    Jessup, J.M.7    Pagano, M.8
  • 41
    • 0031042746 scopus 로고    scopus 로고
    • Cancer prognostics: Past, present and p27
    • Steeg, P. S., and Abrams, J. S. Cancer prognostics: past, present and p27. Nat. Med., 3: 152-154, 1997.
    • (1997) Nat. Med. , vol.3 , pp. 152-154
    • Steeg, P.S.1    Abrams, J.S.2
  • 42
    • 0031048716 scopus 로고    scopus 로고
    • Expression of cell-cycle regulators p27Kip1 and cyclin E, alone and in combination, correlate with survival in young breast cancer patients
    • Porter, P. L., Malone, K. E., Heagerty, P. J., Alexander, G. M., Gatti, L. A., Firpo, E. J., Daling, J. R., and Roberts, J. M. Expression of cell-cycle regulators p27Kip1 and cyclin E, alone and in combination, correlate with survival in young breast cancer patients. Nat. Med. 3: 222-225, 1997.
    • (1997) Nat. Med. , vol.3 , pp. 222-225
    • Porter, P.L.1    Malone, K.E.2    Heagerty, P.J.3    Alexander, G.M.4    Gatti, L.A.5    Firpo, E.J.6    Daling, J.R.7    Roberts, J.M.8
  • 43
    • 0040061124 scopus 로고    scopus 로고
    • Cytogenic and fluorescence in situ hybridization analyses of chromosome 19 aberrations in pancreatic carcinoma: Frequent loss of 19p13.3 and gain of 19p13.1-13.2
    • Hoglund, M., Gorunova, L., Andren-Sandberg, A., Mitelman, F., and Johansson, B. Cytogenic and fluorescence in situ hybridization analyses of chromosome 19 aberrations in pancreatic carcinoma: frequent loss of 19p13.3 and gain of 19p13.1-13.2. Genes Chromosomes Cancer, 21: 8-16, 1998.
    • (1998) Genes Chromosomes Cancer , vol.21 , pp. 8-16
    • Hoglund, M.1    Gorunova, L.2    Andren-Sandberg, A.3    Mitelman, F.4    Johansson, B.5
  • 44
    • 0028954148 scopus 로고
    • Regeion-specific loss of heterozygosity on chromosome 19 is related to the morphologic type of human glioma
    • Ritland, S., Ganju, V., and Jenkins, R. Regeion-specific loss of heterozygosity on chromosome 19 is related to the morphologic type of human glioma. Genes Chromosomes Cancer, 12: 277-282, 1995.
    • (1995) Genes Chromosomes Cancer , vol.12 , pp. 277-282
    • Ritland, S.1    Ganju, V.2    Jenkins, R.3
  • 45
    • 0029091012 scopus 로고
    • Frequent deletion of chromosome 19 and a rare rearrangement of 19pl3.3 involving the insulin receptor gene in human ovarian cancer
    • Amfo, K., Neyns, B., Teugels, E., Lissens, W., Bourgain, C., De Sutter, P., Van damme, B., Vamos, E., and De Greve, J. Frequent deletion of chromosome 19 and a rare rearrangement of 19pl3.3 involving the insulin receptor gene in human ovarian cancer. Oncogene, 11: 351-358, 1995.
    • (1995) Oncogene , vol.11 , pp. 351-358
    • Amfo, K.1    Neyns, B.2    Teugels, E.3    Lissens, W.4    Bourgain, C.5    De Sutter, P.6    Van Damme, B.7    Vamos, E.8    De Greve, J.9


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