Neuronal differentiation and patterning in Xenopus: The role of cdk5 and a novel activator Xp35.2

Developmental Biology

Volumn 207, Issue 1, 1999, Pages 119-132

  Philpott, A ^a   Tsai, L H ^a   Kirschner, M W ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

Author keywords

cdk5; Differentiation; Neural; Xenopus; Xp35.2

Indexed keywords

CYCLINE; PHOSPHOTRANSFERASE;

ANIMAL TISSUE; ARTICLE; ENZYME ACTIVATION; EYE DEVELOPMENT; GENE EXPRESSION; MOLECULAR CLONING; NERVE CELL DIFFERENTIATION; NERVOUS SYSTEM DEVELOPMENT; NEUROECTODERM; NONHUMAN; PRIORITY JOURNAL; XENOPUS;

ANIMALIA; MAMMALIA; VERTEBRATA;

EID: 0033104433     PISSN: 00121606     EISSN: None     Source Type: Journal    
DOI: 10.1006/dbio.1998.9146     Document Type: Article

References (38)

1. Brivanlou A. H., Harland R. M. Expression of an engrailed-related protein is induced in the anterior neural ectoderm of earlyXenopus. Development. 106:1989;611-617.
2. Casarosa S., Andreazzoli M., Simeone A., Barsacchi G. Xrx1, a novelXenopus. Mech. Dev. 61:1997;187-198.
3. Chae T., Kwon Y. T., Bronson R., Dikkes P., Li E., Tsai L. H. Mice lacking p35, a neuronal specific activator of Cdk5, display cortical lamination defects, seizures, and adult lethality. Neuron. 18:1997;29-42.
4. Delalle I., Bhide P. G., Caviness V. S. Jr., Tsai L. H. Temporal and spatial patterns of expression of p35, a regulatory subunit of cyclin-dependent kinase 5, in the nervous system of the mouse. J. Neurocytol. 26:1997;283-296.
5. Ferreiro B., Kintner C., Zimmerman K., Anderson D., Harris W. A. XASH genes promote neurogenesis inXenopus. Development. 120:1994;3649-3655.
6. Gao C. Y., Zakeri Z., Zhu Y., He H., Zelenka P. S. Expression of Cdk5, p35, and Cdk5-associated kinase activity in the developing rat lens. Dev. Genet. 20:1997;267-275.
7. Gervasi C., Szaro B. G. TheXenopus laevis. Brain Res. Mol. Brain Res. 33:1995;192-200.
8. Hartenstein V. Early neurogenesis inXenopus: Neuron. 3:1989;399-411.
9. Hemmati-Brivanlou A., de la Torre J. R., Holt C., Harland R. M. Cephalic expression and molecular characterization ofXenopus. Development. 111:1991;715-724.
10. Hirsch N., Harris W. A. Xenopus. J. Neurobiol. 32:1997;45-61.
11. Holt C. E., Bertsch T. W., Ellis H. M., Harris W. A. Cellular determination in theXenopus. Neuron. 1:1988;15-26.
12. Ishiguro K., Kobayashi S., Omori A., Takamatsu M., Yonekura S., Anzai K., Imahori K., Uchida T. Identification of the 23 kDa subunit of tau protein kinase II as a putative activator of cdk5 in bovine brain. FEBS Lett. 342:1994;203-208.
13. Jacobson M., Huang S. Neurite outgrowth traced by means of horseradish peroxidase inherited from neuronal ancestral cells in frog embryos. Dev. Biol. 110:1985;102-113.
14. Lamb T. M., Harland R. M. Fibroblast growth factor is a direct neural inducer, which combined with noggin generates anterior-posterior neural pattern. Development. 121:1995;3627-3636.
15. Lamb T. M., Knecht A. K., Smith W. C., Stachel S. E., Economides A. N., Stahl N., Yancopolous G. D., Harland R. M. Neural induction by the secreted polypeptide noggin [see comments]. Science. 262:1993;713-718.
16. Lee J. E., Hollenberg S. M., Snider L., Turner D. L., Lipnick N., Weintraub H. Conversion ofXenopus. Science. 268:1995;836-844.
17. Lew J., Huang Q. Q., Qi Z., Winkfein R. J., Aebersold R., Hunt T., Wang J. H. A brain-specific activator of cyclin-dependent kinase 5. Nature. 371:1994;423-426.
18. Lew J., Wang J. H. Neuronal cdc2-like kinase. Trends Biochem. Sci. 20:1995;33-37.
19. Lustig K. D., Kirschner M. W. Use of an oocyte expression assay to reconstitute inductive signaling. Proc. Natl. Acad. Sci. USA. 92:1995;6234-6238.
20. Lustig K. D., Kroll K., Sun E., Ramos R., Elmendorf H., Kirschner M. W. AXenopus. Development. 122:1996;3275-3282.
21. Ma Q., Kintner C., Anderson D. J. Identification of neurogenin, a vertebrate neuronal determination gene. Cell. 87:1996;43-52.
22. Mathers P. H., Grinberg A., Mahon K. A., Jamrich M. The Rx homeobox gene is essential for vertebrate eye development. Nature. 387:1997;603-607.
23. Meyerson M., Enders G. H., Wu C. L., Su L. K., Gorka C., Nelson C., Harlow E., Tsai L. H. A family of human cdc2-related protein kinases. EMBO J. 11:1992;2909-2917.
24. Nikolic M., Dudek H., Kwon Y. T., Ramos Y. F., Tsai L. H. The cdk5/p35 kinase is essential for neurite outgrowth during neuronal differentiation. Genes Dev. 10:1996;816-825.
25. Ohshima T., Ward J. M., Huh C. G., Longenecker G., Veeranna Pant H. C., Brady R. O., Martin L. J., Kulkarni A. B. Targeted disruption of the cyclin-dependent kinase 5 gene results in abnormal corticogenesis, neuronal pathology and perinatal death. Proc. Natl. Acad. Sci. USA. 93:1996;11173-11178.
26. Pannese M., Polo C., Andreazzoli M., Vignali R., Kablar B., Barsacchi G., Boncinelli E. TheXenopus. Development. 121:1995;707-720.
27. Papalopulu N., Kintner C. A posteriorising factor, retinoic acid, reveals that anteroposterior patterning controls the timing of neuronal differentiation inXenopus. Development. 122:1996;3409-3418.
28. Philpott A., Porro E. B., Kirschner M. W., Tsai L. H. The role of cyclin-dependent kinase 5 and a novel regulatory subunit in regulating muscle differentiation and patterning. Genes Dev. 11:1997;1409-1421.
29. Poon R. Y., Lew J., Hunter T. Identification of functional domains in the neuronal Cdk5 activator protein. J. Biol. Chem. 272:1997;5703-5708.
30. Tang D., Yeung J., Lee K. Y., Matsushita M., Matsui H., Tomizawa K., Hatase O., Wang J. H. An isoform of the neuronal cyclin-dependent kinase 5 (Cdk5) activator. J. Biol. Chem. 270:1995;26897-26903.
31. Tsai L. H., Delalle I., Caviness V. S. Jr., Chae T., Harlow E. p35 is a neural-specific regulatory subunit of cyclin-dependent kinase 5. Nature. 371:1994;419-423.
32. Tsai L. H., Takahashi T., Caviness V. S. Jr., Harlow E. Activity and expression pattern of cyclin-dependent kinase 5 in the embryonic mouse nervous system. Development. 119:1993;1029-1040.
33. Turner D. L., Weintraub H. Expression of achaete-scute homolog 3 inXenopus. Genes Dev. 8:1994;1434-1447.
34. van den Heuvel S., Harlow E. Distinct roles for cyclin-dependent kinases in cell cycle control. Science. 262:1993;2050-2054.
35. Vize P. D., Melton D. A., Hemmati-Brivanlou A., Harland R. M. Assays for gene function in developingXenopus. Methods Cell Biol. 36:1991;367-387.
36. Xiong Y., Zhang H., Beach D. D type cyclins associate with multiple protein kinases and the DNA replication and repair factor PCNA. Cell. 71:1992;505-514.
37. Zheng M., Leung C. L., Liem R. K. Region-specific expression of cyclin-dependent kinase 5 (cdk5) and its activators, p35 and p39, in the developing and adult rat central nervous system. J. Neurobiol. 35:1998;141-159.
38. Zimmerman L. B., De Jesus-Escobar J. M., Harland R. M. The Spemann organizer signal noggin binds and inactivates bone morphogenetic protein 4. Cell. 86:1996;599-606.