Psychological impact of receiving negative BRCA1 mutation test results in Ashkenazim

Genetics in Medicine

Volumn 1, Issue 3, 1999, Pages 74-79

  Friedman, Lois C ^a  

^a Department of Psychiatry and Behavioral Sciences ^*  (United States)

Author keywords

Ashkenazim; Community based testing; Negative brca1 mutation results; Psychological impact

Indexed keywords

ADULT; AGED; ANXIETY; ARTICLE; BLOOD; BREAST TUMOR; COMPARATIVE STUDY; CONFIDENTIALITY; DEMOGRAPHY; EMPIRICAL APPROACH; FEMALE; FOLLOW UP; GENETIC PREDISPOSITION; GENETIC SCREENING; GENETICS; GENETICS AND REPRODUCTION; HUMAN; INTERPERSONAL COMMUNICATION; JEW; MIDDLE AGED; MUTATION; PERSONALITY TEST; PSYCHOLOGICAL ASPECT; RISK FACTOR; STANDARD; STATISTICAL MODEL; STATISTICS; TUMOR SUPPRESSOR GENE;

EMPIRICAL APPROACH; GENETICS AND REPRODUCTION;

ADULT; AGED; AGED, 80 AND OVER; ANXIETY; BREAST NEOPLASMS; CONFIDENTIALITY; DEMOGRAPHY; DISCLOSURE; FEMALE; FOLLOW-UP STUDIES; GENES, BRCA1; GENETIC PREDISPOSITION TO DISEASE; GENETIC SCREENING; HUMANS; JEWS; LOGISTIC MODELS; MIDDLE AGED; MUTATION; RISK FACTORS; TEST ANXIETY SCALE;

EID: 0033086397     PISSN: 10983600     EISSN: None     Source Type: Journal    
DOI: 10.1097/00125817-199903000-00003     Document Type: Article

References (28)

1. American Cancer Society. Cancer facts and figures - 1997. Atlanta: American Cancer Society, 1997.
2. Claus EB, Risch N, Thompson WD. Genetic analysis of breast cancer in the Cancer and Steroid Hormone Study. Am J Hum Genet 1991;48:232-242.
3. King MC, Rowell SE, Love SM. Inherited breast and ovarian cancer: What are the risks? What are the choices? JAMA 1993;269:1975-1980.
4. Couch FJ, DeShano ML, Blackwood MA, Calzone K, Stopfer J, Campeau L, Ganguly A, Rebbeck T, Weber BL. BRCA1 mutations in women attending clinics that evaluate the risk of breast cancer. N Engl J Med 1997;336:1409-1415.
5. Struewing JP, Hartge P, Wacholder S, Baker SM, Berlin M, McAdams M, Timmerman MM, Brody LC, Tucker MA. The risk of cancer associated with specific mutations of BRCA1 and BRCA2 among Ashkenazi Jews. N Engl J Med 1997;336:1401-1408.
6. Roa BB, Boyd AA, Volcik K, Richards CS. Ashkenazi Jewish population frequencies for common mutations in BRCA1 and BRCA2. Nar Genet 1996;14:185-187.
7. Couch FJ, Farid LM, DeShano ML, Tavtigian SV, Calzone K, Campeau L, Peng Y, Bogden B, Chen Q, Neuhausen S, Shattuck-Eidens D, Godwin AK, Daly M, Radford DM, Sedlacek S, Rommens J, Simard J, Garber J, Merajver S, Weber BL. BRCA2 germline mutations in male breast cancer cases and breast cancer families. Mir Genet 1996;13:123-125.
8. Neuhausen S, Gilewski T, Norton L, Tran T, McGuire P, Swensen J, Hampel H, Borgen P, Brown K, Skolnick M, Shattuck-Eidens D, Jhanwar S, Goldgar D, Offit K. Recurrent BRCA2 6174delT mutations in Ashkenazi Jewish women affected by breast cancer. Nat Genet 1996;13:126-128.
9. Oddoux C, Struewing JP, Clayton CM, Neuhausen S, Brody LC, Kaback M, Haas B, Norton L, Borgen P, Jhanwar S, Goldgar D, Ostrer H, Offit K. The carrier frequency of the BRCA2 6174delT mutation among Ashkenazi Jewish individuals is approximately 1%. Nat Genet 1996;14:188-190.
10. Ford D, Easton DF, Petro J. Estimates of the gene frequency of BRCA1 and its contribution to breast and ovarian cancer incidence. Am J Hum Genet 1995;57:1457-1462.
11. Shattuck-Eidens D, Oliphant A, McClure M, McBride C, Gupte J, Rubano T, Pruss D, Tavtigian SV, Teng DH, Adey N, Staebell M, Gumpper K, Lundstrom R, Hulick M, Kelly M, Holmen J, Lingenfelter B, Manley S, Fujimura F, Luce M, Ward B, Cannon-Albright L, Steele L, Offit K, Thomas A. BRCA1 sequence analysis in women at high risk for susceptibility mutations. JAMA 1997;278:1242-1250.
12. Giardiello FM, Brensinger JD, Petersen GM, Luce MC, Hylind LM, Bacon JA, Booker SV, Parker RD, Hamilton SR. The use and interpretation of commercial APC gene testing for familial adenomatous polyposis. N Engl J Med 1997;336:823-827.
13. Richards CS, Ward PA, Roa BB, Friedman LC, Boyd AA, Kuenzli G, Dunn JK, Plon SE. Screening for 185delAG in the Ashkenazim. Am J Hum Genet 1997;60:1085-1098.
14. DeMarchi JM, Richards CS, Fenwick RG, Pace R, Beaudet AL. A robotics-assisted procedure for large scale cystic fibrosis mutation analysis. Hum Mutat 1994;4:281-290.
15. Curran SL, Andrykowski MA, Studts JL. Short form of the Profile of Mood States (POMS-SF): Psychometric information. Psychol Assessment 1995;7:80-83.
16. Me Nair D, Lorr M, Droppleman L. Profile of Mood States. San Diego, California: EdITS/Educational and Industrial Testing Service, 1981.
17. Lerman C, Daly M, Masny A, Balshem A. Attitudes abut genetic testing for breast-ovarian cancer susceptibility. J Clin Oncol 1994;12:843-850.
18. Schwartz MD, Lerman C, Miller SM, Daly M, Masny A. Coping disposition, perceived risk and psychological distress among women at increased risk for ovarian cancer. Health Psychol 1995;14:232-253.
19. Lerman C, Schwartz MD, Miller SM, Daly M, Sands C, Rimer BK. A randomized trial of breast cancer risk counseling: Interacting effects of counseling, educational level, and coping style. Health Psychol 1996;15:75-83.
20. Horowitz M, Wilner N, Alvarez W. Impact of Events Scale: A measure of subjective stress. Psychosom Med 1979;41:209-218.
21. Kash KM, Holland JC, Halper MS, Miller DG. Psychological distress and surveillance behaviors of women with a family history of breast cancer. J Natl Cancer Inst 1992;84:24-30.
22. Croyle RT, Smith KR, Botkin JR, Baty B, Nash J. Psychological responses to BRCA1 mutation testing: Preliminary findings. Health Psychol 1997;16:63-72.
23. Lerman C, Schwartz MD, Lin TH, Hughes C, Narod S, Lynch HT. The influence of psychological distress on use of genetic testing for cancer risk. J Consult Clin Psychol 1997;65:414-120.
24. Love RR, Evans AM, Josten DM. The accuracy of patient reports of a family history of cancer. J Chronic Dis 1985;38:289-293.
25. Parent M-E, Ghadirian P, Lacroix A, Perret C. The reliability of recollections of family history: Implications for the medical provider. J Cancer Educ 1997;12:114-120.
26. Airewele G, Adatto P, Cunningham J, Mastromarino C, Spencer C, Sharp M, Sigurdson A, Bondy M. Family history of cancer in patients with glioma: A validation study of accuracy. J Natl Cancer Inst 1998;90:543-544.
27. Vernon SW, Gritz ER, Peterson SK, Amos CI, Perz CA, Baile WF, Lynch PM. Correlates of psychologic distress in colorectal cancer patients undergoing genetic testing for hereditary colon cancer. Health Psychol 1997;16:73-86.
28. Geller G, Bernhardt BA, Helzlsouer K, Holtzman N, Stefanek M, Wilsox PM. Informed consent and BRCA1 testing. Nat Genet 1995;11:364.