BCL-2 expression and inhibin-A in adrenal neoplasms: A comparative study

International Journal of Molecular Medicine

Volumn 3, Issue 3, 1999, Pages 271-274

  Fogt, F ^a,g   Zimmerman, R L ^b   Mulligan, N ^c   Vortmeyer, A O ^d   Poremba, C ^e   Harris, C A ^f   Alsaigh, N ^a   Tomaszewski, J E ^b   Nikulasson, S T ^c  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b UNIVERSITY OF MÜNSTER   (Germany)

^c UNIVERSITY OF ICELAND   (Iceland)

^d BOSTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^e NATIONAL INSTITUTES OF HEALTH   (United States)

^f Dianon Systems   (United States)

^g PENN PRESBYTERIAN MEDICAL CENTER   (United States)

Author keywords

Adrenal cortex; Adrenal cortical carcinoma; BCL 2; Immunohistochemistry; Inhibin A; Pheochromocytoma

Indexed keywords

INHIBIN; PROTEIN BCL 2; TUMOR MARKER;

ADENOMA; ADRENAL CORTEX; ADRENAL MEDULLA; ADRENAL TUMOR; ARTICLE; CARCINOMA; CHEMISTRY; CLASSIFICATION; COMPARATIVE STUDY; DIFFERENTIAL DIAGNOSIS; HUMAN; IMMUNOHISTOCHEMISTRY; METHODOLOGY; PATHOLOGY; PHEOCHROMOCYTOMA; TISSUE FIXATION;

ADENOMA; ADRENAL CORTEX; ADRENAL GLAND NEOPLASMS; ADRENAL MEDULLA; CARCINOMA; DIAGNOSIS, DIFFERENTIAL; HUMANS; IMMUNOHISTOCHEMISTRY; INHIBINS; PHEOCHROMOCYTOMA; PROTO-ONCOGENE PROTEINS C-BCL-2; TISSUE FIXATION; TUMOR MARKERS, BIOLOGICAL;

EID: 0033085752     PISSN: 11073756     EISSN: None     Source Type: Journal    
DOI: 10.3892/ijmm.3.3.271     Document Type: Article

References (15)

1. Komminoth P, Roth J, Schroeder S, Saremaslani P and Heitz PU: Overlapping expression of immunohistochemical markers and synaptophysin mRNA in pheochromocytomas and adrenocortical carcinomas. Implications for the differential diagnosis of adrenal gland tumors. Lab Invest 72: 424-431, 1995.
2. Cope O, Labbe JP, Raker JW and Bland EF: Pheochromocytoma and adrenal cortical adenoma. Report of a case with both tumors and discussion of their relation. J Clin Endocrinol Metab 12: 875-880,1952.
3. Ramsay JA, Asa SL, van Nostrand AWP, Hassaram ST and de Harven EP: Lipid degeneration in pheaochromocytomas mimicking adrenal cortical tumors. Am J Surg Pathol 11:480-486, 1987.
4. Miettinen M: Neuroendocrine differentiation in adrenocortical carcinoma: new immunohistochemical findings supported by electron microscopy. Lab Invest 66: 169-174, 1992.
5. Schroder S, Niendorf A, Achilles E, Dietel M, Padberg BC, Beisiegel U, Dralle H, Bressel M and Kloppel G: Immunocytochemical differential diagnosis of adrenocortical neoplasms using the monoclonal antibody D11. Virchows Arch (A) 417: 89-96, 1990.
6. Tartour E, Caillou B, Tenenbaum F, Schroder S, Luciani S, Talbot M and Schlumberger M: Immunohistochemical study of adrenocortical carcinoma. Predictive value of the D11 monoclonal antibody. Cancer 72: 3296-3303, 1993.
7. Chivite A, Matias-Guiu X, Pons C, Algaba F and Prat J: Inhibin A expression in adrenal neoplasms: a new immunohistochemical marker for adrenocortical tumors. Appl Immunohistochem 6: 42-49,1998.
8. Fogt F, Vortmeyer AO, Poremba C, Minda M, Harris CA and Tomaszewski JE: bcl-2 expression in normal adrenal glands and in adrenal neoplasms. Mod Pathol 8: 716-720, 1998.
9. Weiss LM: Comparative histologic study of 43 metastasizing and non-metastasizing adrenocortical tumors. Am J Surg Pathol 8: 163-169,1984.
10. Van Slooten H, Schaberg A, Smeenk D and Moolenaar AJ: Morphologic characteristics of benign and malignant adrenocortical tumors. Cancer 55: 766-773,1985.
11. Hough AJ, Hollifield JW, Page DL and Hartmann WH: Prognostic factors in adrenal cortical tumors. A mathematical analysis of clinical and morphologic data. Am J Clin Pathol 72: 390-399, 1979.
12. Iczkowski KA, Bostwick DC, Roche PC and Cheville JC: Inhibin A is a sensitive and specific marker for testicular sex cord-stromal tumors. Mod Pathol 11: 774-779,1998.
13. Cheifetz S, Ling N, Guillemin R and Massague J: A surface component on GH3 pituitary cells that recognizes transforming growth factor-beta, activin, and inhibin. J Biol Chem 263: 17225-17228, 1988.
14. Tao XJ, Tilly KI, Maravei DV, Shifren JL, Krajewski S, Reed JC, Tilly JL and Isaacson KB: Differential expression of members of the bcl-2 gene family in proliferative and secretory human endometrium: glandular epithelial cell apoptosis is associated with increased expression of bax. J Clin Endocrinol Metab 82-2738-2746, 1997.
15. Billig H, Furuta I and Hsueh AJ: Estrogens inhibit and androgens enhance ovarian granulosa cell apoptosis. Endocrinology 133: 2204-2212, 1993.