Functional analysis of T lymphocytes infiltrating the dermis and epidermis of post-burn hypertrophic scar tissues

Burns

Volumn 25, Issue 1, 1999, Pages 43-48

  Bernabei, Paola ^a   Rigamonti, Laura ^a   Ariotti, Silvia ^a   Stella, Maurizio ^d   Castagnoli, Carlotta ^b   Novelli, Francesco ^a,c  

^a UNIVERSITY OF TURIN   (Italy)

^b Piedmontese Found for Burn S   (Italy)

^c SAN LUIGI GONZAGA HOSPITAL   (Italy)

^d NONE

Author keywords

Burns; Cytokines; Hypertrophic scars; Th1 Th2

Indexed keywords

CD3 ANTIGEN; CD8 ANTIGEN; CELL SURFACE MARKER; CYTOKINE; GAMMA INTERFERON; INTERLEUKIN 4;

ARTICLE; BURN SCAR; CLINICAL ARTICLE; DERMIS; DISEASE SEVERITY; EPIDERMIS; HUMAN; HUMAN CELL; HUMAN TISSUE; HYPERTROPHIC SCAR; LYMPHOCYTE CLONE; LYMPHOCYTIC INFILTRATION; PHENOTYPE; POLARIZATION; REMISSION; T LYMPHOCYTE;

ANTIGENS, CD4; ANTIGENS, CD8; BURNS; CICATRIX, HYPERTROPHIC; DERMIS; EPIDERMIS; HUMANS; IMMUNOPHENOTYPING; INTERFERON TYPE II; INTERLEUKIN-4; RECEPTORS, ANTIGEN, T-CELL, ALPHA-BETA; SKIN; T-LYMPHOCYTE SUBSETS; T-LYMPHOCYTES;

EID: 0033083595     PISSN: 03054179     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0305-4179(98)00128-4     Document Type: Article

References (24)

1. Castagnoli C., Trombotto C., Ondei S., et al. Characterization of T-cell subsets infiltrating post-burn hypertrophic scar tissues. Burns. 23:1997;565-572.
2. Castagnoli C., Stella M., Magliacani G., Alasia S.T., Richiardi P.M. Anomalous expression of HLA class II molecules on keratinocytes and fibroblasts in hypertrophic scars consequent to thermal injury. Clin Exp Immunol. 82:1990;350-354.
3. Castagnoli C., Stella M., Magliacani G., Ferrone S., Richiardi P.M. Similar ectopic expression of ICAM-1 and HLA Class II molecules in hypertrophic scars following thermal injury. Burns. 20:1994;430-433.
4. Castagnoli C., Stella M., Menegatti E., Calcagni M., Magliacani G., Teich Alasia S., Alessio M. CD36 expression in hypertrophic scars. Annals of Mediterranean Burns Club. 8:1995;214-218.
5. Castagnoli C., Stella M., Berthod C., Magliacani G., Richiardi P.M. TNF production in hypertrophic scarring. Cell Immunol. 147:1993;51-63.
6. + T cells through IL-12 produced by Listeria-induced macrophages. Science. 260:1993;547-549.
7. + T cells from T cell receptor transgenic mice. J Exp Med. 176:1992;1091-1098.
8. Hauser C. Cultured epidermal Langherans cells activate effector T cells for contact sensitivity. J Invest Dermatol. 95:1990;436-440.
9. Kupper TS, Luger TA, Schwarz T. editors. The Second Decade of Epidermal Cytokines: an Overview. Dekker, New York, 1993. p. 239.
10. Moretta A., Pantaleo G., Moretta L., Cerottini J.C., Mingari M.C. Direct demonstration of the clonogenic potential of every human peripheral blood T cell. Clonal analysis of HLA-DR expression and cytolytic activity. J Exp Med. 157:1983;743-754.
11. Billiau A. Interferon γ. Biology and role in pathogenesis. Adv Immunol. 62:1996;61-130.
12. Maher D.W., Davis I., Boyd A.W., Morstyn G. Human interleukin-4: an immunomodulator with potential therapeutic applications. Prog Growth Factor Res. 3:1991;43-56.
13. Mosmann T.R., Coffman R.L. Th1 and Th2 cells: different patterns of lymphokine secretion lead to different functional properties. Annu Rev Immunol. 7:1989;145-173.
14. Manetti R., Gerosa F., Giudizi M.G., et al. Interleukin 12 induces stable priming for interferon gamma (IFN-γ) production during differentiation of human T helper (Th) cells and transient IFN-γ production in established Th2 cell clones. J Exp Med. 179:1994;1273-1283.
15. Novelli F., Giovarelli M., Reber-Liske R., Virgallita G., Garotta G., Forni G. Blockade of physiologically secreted IFN-γ inhibits human T lymphocyte and natural killer cell activation. J Immunol. 147:1991;1445-1452.
16. Novelli F., Di Pierro F., Francia di Celle P., Bertini S., Affaticati P., Garotta G., Forni G. Environmental signals influencing expression of the IFN-γ receptor on human T cells control whether IFN-γ promotes proliferation or apoptosis. J Immunol. 152:1994;496-504.
17. Novelli F., Bernabei P., Ozmen L., et al. Switching on of the proliferation or apoptosis of activated T human lymphocytes by IFN-γ is correlated with the differential expression of the alpha and beta chains of its receptor. J Immunol. 157:1996;1935-1943.
18. Novelli F., D'Elios M.M., Bernabei P., et al. Expression and role in apoptosis of the alpha and beta chains of the IFN-γ receptor on human Th1 and Th2 clones. J Immunol. 159:1997;206-213.
19. Carson W.E., Giri J.G., Lindemann M.J., et al. Interleukin (IL) 15 is a novel cytokine that activates human natural killer cells via components of the IL-2 receptor. J Exp Med. 180:1994;1395-1401.
20. Wilkinson P.C., Liew F.Y. Chemoattraction of human blood T lymphocytes by IL-15. J Exp Med. 195:1995;1255-1262.
21. Lenardo M.J. Fas and the art of lymphocyte maintenance. J Exp Med. 183:1996;721-724.
22. Harrop A.R., Ghahary A., Scott P.G., Forsyth N., Uji-Friedland A., Tredget E.E. Regulation of collagen synthesis and mRNA expression in normal and hypertrophic scars fibroblasts in vitro by interferon-gamma. J Surg Res. 58:1995;471-477.
23. Tredget E.E., Nedelec B., Scott P.G., Ghahary A. Hypertrophic scars, keloids, and contractures. The cellular and molecular basis for therapy. Surg Clin N Am. 77:1997;701-730.
24. Wang R., Ghahary A., Shen Y.J., Scott P.G., Tredget E.E. Nitric oxide synthase expression and nitric oxide production are reduced in hypertrophic scar tissues and fibroblasts. J Invest Dermatol. 108:1997;438-444.