Characterization of T-cell subsets infiltrating post-burn hypertrophic scar tissues

Burns

Volumn 23, Issue 7-8, 1997, Pages 565-572

  Castagnoli, Carlotta ^a   Trombotto, Claudia ^a   Ondei, Sabzima ^a   Stella, Maurizio ^b,c   Calcagni, Maurizio ^b   Magliacani, Gilberto ^b   Alasia, Simone Teich ^a  

^a Piedmont Found Studs Res on Burns   (Italy)

^b Trauma Centre   (Italy)

^c Department of Plastic Surgery   (Italy)

Author keywords

Burns; Hypertrophic scars; T cell subset

Indexed keywords

CD3 ANTIGEN; CD4 ANTIGEN; CD8 ANTIGEN; CYTOKINE;

ADOLESCENT; AGED; ARTICLE; B LYMPHOCYTE; BURN SCAR; CLINICAL ARTICLE; CONTROLLED STUDY; CYTOKINE RELEASE; DERMIS; EPIDERMIS; FEMALE; HUMAN; HUMAN TISSUE; HYPERTROPHIC SCAR; IMMUNOHISTOCHEMISTRY; LANGERHANS CELL; LYMPHOCYTE ACTIVATION; LYMPHOCYTIC INFILTRATION; MACROPHAGE; MALE; NATURAL KILLER CELL; T LYMPHOCYTE SUBPOPULATION;

ADOLESCENT; ADULT; AGED; ANTIBODIES, MONOCLONAL; BIOLOGICAL MARKERS; BIOPSY, NEEDLE; BURNS; CD4 LYMPHOCYTE COUNT; CD4-CD8 RATIO; CICATRIX, HYPERTROPHIC; CULTURE TECHNIQUES; FEMALE; HLA-DR ANTIGENS; HUMANS; MACROPHAGES; MALE; MIDDLE AGED; RADIOIMMUNOASSAY; RECEPTORS, INTERLEUKIN-2; REFERENCE VALUES; SENSITIVITY AND SPECIFICITY; T-LYMPHOCYTE SUBSETS; WOUND HEALING;

EID: 0031426681     PISSN: 03054179     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0305-4179(97)00070-3     Document Type: Article

References (25)

1. Linares H. A. From wound to scar. Burns 1996; 22: 339-352.
2. Muir I. F. K. On the nature of keloid and hypertrophic scars. British Journal of Plastic Surgery 1990; 43: 61-69.
3. Magliacani G., Stella M., Castagnoli C., Trombotto C., Ondei S., Calcagni M. Post-burn pathological scar: clinical aspects and therapeutic approach. Annales of Mediterranean Burns Club 1997; 10: 105-109.
4. McCauley R. L, Chopra V., Li Y., Herdon D. N., Robson M. C. Altered cytokine production in black patients with keloids. Journal of Clinical Immunology 1992; 12: 300-308.
5. Ghahary A., Shen Y. J., Scott P. G., Gong Y., Tredget E. E. Enhanced expression of m RNA for trasforming growth factor b1, type I and type III procollagen in post-burn hypertrophic scar tissue. Journal of Clinical Laboratory Medicine 1993; 122: 465-473.
6. Kovacs E. J. Fibrogenic cytokines: the role of immune mediators in the development of scar tissue. Immunology Today 1991; 12: 17-23.
7. Castagnoli C., Stella M., Menegatti E., Calcagni M., Magliacani G., Teich Alsia S., Alessio M. CD36 expression in hypertrophic scars. Annales of Mediterranean Burns Club 1995; 8: 214-218.
8. Castagnoli C., Stella M., Magliacani G., Ferrone S., Momigliano Richiardi P. Similar ectopic expression of ICAM-1 and HLA class II molecules in hypertrophic scars following thermal injury. Burns 1994; 20: 430-433.
9. Castagnoli C., Trombotto C., Stella M., Calcagni M., Magliacani G. Expression of functional IL-2 receptor in post-burn hypertrophic scars. Annales of Mediterranean Burns Club 1996; 9: 216-221.
10. Peruccio D., Castagnoli C., Stella M., D'Alfonso S., Momigliano Richiardi P., Magliacani G., Teich Alasia S. Altered biosynthesis of TNF alpha is involved in post burn hypertrophic scars. Burns 1994; 20: 118-121.
11. Castagnoli C., Stella M., Magliacani G., Richiardi P. The role of TNF alpha and beta cytokines in scar hypertrophy in burn patients: an immunohistochemical study. Annales of Mediterranean Burns Club 1995; 8: 23.
12. Linares H. A. Proteoglycan-lymphocyte association in the development of hypertrophic scars. Burns 1990; 16: 21-24.
13. Castagnoli C., Stella M., Magliacani G., Teich-Alasia S., Richiardi P. Anomalous expression of HLA class II molecules on keratinocytes and fibroblasts in hypertrophic scars consequent to thermal injury. Clinical and Experimental Immunology 1990; 82: 350-354.
14. Barbul A., Breslin R. J., Woodyard J. P., WasserKrug H. L., Efron G. The effect of in vitro T helper and T suprressor lymphocyte depletion on wound healing. Annals of Surgery 1989; 209: 479-483.
15. Barbul, A. Role of T cell-dependent immune system in wound healing. In Growth Factors and Other Aspects of Wound Healing: Biological and Clinical Implication, ed. Barbul A. et al. Alan R. Liss, New York, 1988, pp. 161-175.
16. Groh V., Fabbi M., Hochstenbach F., Maziarz R., Strominger J. Double-negative (CD4 CD8) lymphocytes bearing T-cell receptor α and β chains in normal human skin. Proceedings of the National Academy of Sciences of the USA 1989; 86: 5059-5063.
17. Bos D. J., Kapsenberg J. The skin immune system; progress in cutaneous biology. Immunology Today 1993; 14: 75-78.
18. Nikaein A., Phillips C., Gilbert S., Silverman A., Stone M., Menter A. Characterization of skin infiltrating lymphocytes in patients with psoriasis. Journal of Investigative Dermatology 1991; 96: 3-9.
19. Stella M., Castagnoli C., Trombotto C., Magliacani G., Teich Alasia S. Interrelationship between immunocompetent and structural cells in post-burn scars. European Journal of Plastic Surgery 1997; 00: 000-000.
20. Griffiths C. E. M., Voorhees J. J., Nickoloff B. J. Characterization of ICAM-1 and HLA-DR expression in normal and inflamed skin: modulation by recombinant gamma interferon and tumor necrosis factor. Journal of the American Academy of Dermatology 1989; 20: 617-624.
21. Vejlsgaard G. L., Ralfkiaer E., Avnstorp C., Czajkowski M., Marlin S. D., Rothlein R. Kinetics and characterization of ICAM-1 expression on keratinocytes in various inflammatory skin lesions and malignant cutaneous lymphomas. Journal of the American Academy of Dermatology 1989; 20: 782-792.
22. Kupper T. S. Immune processes in cutaneous tissues. Mechanisms and speculation. Journal of Clinical Investigation 1990; 86: 1783-1789.
23. Nickoloff B. J., Mitra R. S., Green J., Zheng X. G., Shimizu Y., Thompson C., Turka L. A. Accesory cell function of keratinocytes for superantigens. Journal of Immunology 1993; 150: 2148-2159.
24. Nickoloff B. J., Turka L. A. Immunological functions of non-professional antigen-presenting cells: new insights from studies of T-cell interactions with keratinocytes. Immunology Today 1994; 15: 464-468.
25. Cracco C., Stella M., Teich Alasia S., Filogamo G. Comparative study of Langerhans cells in normal and pathological human scars II. Hypertrophic scar. European Journal of Histochemistry 1992; 36: 53-56.