In vitro methionine oxidation of Escherichia coli-derived human stem cell factor: Effects on the molecular structure, biological activity, and dimerization

Protein Science

Volumn 5, Issue 6, 1996, Pages 1165-1173

  Hsu, Yueh Rong ^a   Narhi, Linda O ^a   Spahr, Christopher ^a   Langley, Keith E ^a   Lu, Hsieng S ^a  

^a AMGEN INC   (United States)

Author keywords

dimerization; methionine oxidation; stem cell factor; structure function

Indexed keywords

HYDROGEN PEROXIDE; METHIONINE; METHIONINE SULFOXIDE; PEPTIDE; STEM CELL FACTOR;

ARTICLE; CHEMICAL STRUCTURE; CIRCULAR DICHROISM; DIMERIZATION; ESCHERICHIA COLI; FLUORESCENCE SPECTROSCOPY; HUMAN; HUMAN CELL; MASS SPECTROMETRY; OXIDATION; PEPTIDE MAPPING; PRIORITY JOURNAL; PROTEIN TERTIARY STRUCTURE; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; STRUCTURE ACTIVITY RELATION;

ESCHERICHIA COLI; TRIXIS;

EID: 0029897141     PISSN: 09618368     EISSN: None     Source Type: Journal    
DOI: 10.1002/pro.5560050619     Document Type: Article

References (20)

1. Amiconi G, Ascoli F, Barra D, Bertollini A, Matarese R, Verzili D, Brunori M. 1989. Selective oxidation of methionine beta(55)D6 as the alpha I beta 1 interface in hemoglobin completely destabilizes the T-state. J Biol Chem 264:17745-17749.
2. Anderson DM, Lyman SD, Baird A, Wignall JM, Eisenman J, Rauch C, March CJ, Boswell HS, Gimpel SD, Cosman D, Williams DE. 1990. Molecular cloning of mast cell growth factor, a hematopoietin that is active in both membrane bound and soluble forms. Cell 63:235-243.
3. Arakawa T, Yphantis D, Lary J, Narhi L, Lu H, Prestrelski S, Clogston C, Zsebo K, Mendiaz E, Wypych J, Langley E. 1991. Glycosylated and unglycosylated recombinant-derived human stem cell factor are dimeric and have extensive regular secondary structure. J Biol Chem 266:18942-18948.
4. Coltrera M, Rosenblott M, Potts JT. 1980. Analogues of parathyroid hormone containing D-amino acids: Evaluation of biological activity and stability. Biochemistry 19:4380-4385.
5. Erlich H. 1989. PCR technology, principles and applications for DNA amplification. New York: Stockton Press. p 61.
6. Galli SJ, Zsebo KM, Geissler EN. 1994. The kit ligand, stem cell factor. Adv Immunol 55:1-96.
7. Guptasarma P, Balasubramanian D. 1992. Hydroxyl radical mediated damage to proteins, with special reference to the crystallins. Biochemistry 31:4296-4303.
8. Langley KE, Wypych J, Mendiaz EA, Clogston CL, Parker VP, Farrar DH, Brothers MO, Satyagal VN, Leslie I, Birkett NC, Smith KA, Baltera RF Jr, Lyons DE, Hogan JM, Crandall C, Boone TC, Pope JA, Karkare SB, Zsebo KM, Sachdev RK, Lu HS. 1992. Purification and characterization of soluble forms of human and rat stem cell factor recombinantly expressed by Escherichia coli and by Chinese hamster ovary cells. Arch Biochem Biophys 295:21-28.
9. Lu HS, Chang WC, Mendiaz EA, Mann MB, Langley KE, Hsu YR. 1995. Spontaneous dissociation-association of monomers of the human stem cell factor dimer. Biochem J 305:563-568.
10. Manning MC, Patel K, Borchardt RT. 1989. Stability of protein pharmaceuticals. Pharmaceutical Res 6:903-918.
11. Martin FH, Suggs SV, Langley KE, Lu HS, Ting J, Okino KH, Morris CF, McNiece IK, Jacobsen FW, Mendiaz EA, Birkett NC, Smith KA, Johnson MJ, Parker VP, Flores JC, Patel AC, Fisher EF, Erjavec HO, Herrera CJ, Wypych J, Sachdev RK, Pope JA, Leslie I, Wen D, Lin CH, Cupples RL, Zsebo KM. 1990. Primary structure and functional expression of rat and human stem cell factor DNAs. Cell 63:203-211.
12. McNiece IK, Langley KE, Zsebo KM. 1991a. The role of recombinant stem cell factor in early B cell development. Synergistic interaction with IL-7. J Immunol 140:3785-3790.
13. McNiece IK, Langley KE, Zsebo KM. 1991b. Recombinant human stem cell factor synergizes with GM-CSF, G-CSF, IL-3, and EPO to stimulate human progenitor cells of the myeloid and erythroid lineages. Exp Hematol 19:226-231.
14. Nocka K, Buck J, Levi E, Besmer P. 1990. Candidate ligand for the c-kit transmembrane kinase receptor: KL, a fibroblast-derived growth factor stimulates mast cells and erythroid progenitors. EMBO J 9:3287-32946.
15. 2-macroglobulin tetramers into dysfunctional dimers. J Biol Chem 269:4683-4691.
16. Smith KA, Zsebo KM. 1992. Measurement of human and murine stem cell factor. In: Coligan JE, Kruisbeek AM, Margulies DH, Shevach EM, Strober W, eds. Current protocols in immunology. pp 6.17.1-6.17.11.
17. Strandberg L, Lawrence D, Johansson L, Tor N. 1991. The oxidative inactivation of plasminogen activator inhibitor type 1 results from a conformational change in the molecule and does not required the involvement of the P 1 methionine. J Biol Chem 266:13852-13858.
18. Teh LC, Murphy L, Huq N, Surus A, Friesen H, Lazarus L, Chapman G. 1987. Methionine oxidation in human growth hormone and human chononic somatomammotropin. Effects on receptor binding and biological activities. J Biol Chem 262:6472-6477.
19. Vale W, Spiess J, Rivier C, Rivier J. 1981. Characterization of a 41-residue ovine hypothalamic peptide that stimulates secretion of corticotropin and beta-endorphin. Science 213:1394-1397.
20. Zsebo KM, Wypych J, McNiece IK, Lu HS, Smith KA, Karkare SB, Sachdev RK, Yuschenkoff VN, Birkett NC, Williams LR, Satyagal VN, Tung W, Bosselman RA, Mendiaz EA, Langley KE. 1990. Identification, purification, and biological characterization of hematopoietic stem cell factor from Buffalo rat liver-conditioned medium. Cell 63.195-201.