Fatal outbreaks of proliferative enteritis caused by Lawsonia intracellularis in young colony-raised rhesus macaques

Journal of Medical Primatology

Volumn 28, Issue 1, 1999, Pages 11-18

  Klein, E C ^a   Gebhart, C J ^b   Duhamel, G E ^c  

^a UNIVERSITY OF PITTSBURGH   (United States)

^b UNIVERSITY OF MINNESOTA   (United States)

^c UNIVERSITY OF NEBRASKA LINCOLN   (United States)

Author keywords

Adenomatosis; Bacteria; Enteropathy; Ileum; Immunohistochemistry; Intracellular; Monkey; Necrotizing; Pathogen; Proliferative

Indexed keywords

ANIMAL; ANIMAL DISEASE; ARTICLE; BACTERIAL INFECTION; BACTERIUM; COMPARATIVE STUDY; ELECTRON MICROSCOPY; ENTERITIS; EPIDEMIC; FEMALE; ISOLATION AND PURIFICATION; MACACA; MALE; MICROBIOLOGY; MONKEY DISEASE; PATHOGENICITY; PATHOLOGY; SPECIES DIFFERENCE; SWINE; ULTRASTRUCTURE;

ANIMALS; BACTERIA; BACTERIAL INFECTIONS; DISEASE OUTBREAKS; ENTERITIS; FEMALE; MACACA MULATTA; MALE; MICROSCOPY, ELECTRON; MONKEY DISEASES; SPECIES SPECIFICITY; SWINE;

EID: 0033070545     PISSN: 00472565     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1600-0684.1999.tb00084.x     Document Type: Article

References (33)

1. BASKIN GB, MURPHEY-CORB M, WATSON EA, MARTIN LN: Necropsy findings in rhesus monkeys experimentally infected with cultured simian immunodeficiency virus (SIV)/delta. Vet Pathol 25(6):456-467, 1988.
2. COOPER DM, GEBHART CJ: Comparative aspects of proliferative enteritis. JAVMA 212(9):1446-1451, 1998.
3. COOPER DM, SWANSON DL, GEBHART CJ: Diagnosis of proliferative enteritis in frozen and formalin fixed, paraffin-embedded tissues from a hamster, horse, deer and ostrich using a Lawsonia intracellularis - Specific multiplex PCR. Vet Microbiol 54:47-62, 1997.
4. DROLET R, LAROCHELLE D, GEBHART CJ: Proliferative enteritis associated with Lawsonia intracellularis (ileal symbiont intracellularis) in white-tailed deer. J Vet Diag Invest 8(2):250-253, 1996.
5. DUHAMEL GE, KLEIN EC, ELDER RO, GEBHART CJ: Subclinical proliferative enteropathy in sentinel rabbits associated with Lawsonia intracellularis. Vet Pathol 35:300-303, 1998.
6. DUHAMEL GE, ELDER RO, MUNIAPPA N, MATHIESEN MR, WONG VJ, TARARA RP: Colonic spirochetal infections in nonhuman primates that were associated with Brachyspira aalborgi, Serpulina pilosicoli, and unclassified flagellated bacteria. Clin Infect Dis 25(Supp 2):186-188, 1997.
7. DUHAMEL GE, WHEELDON EB: Intestinal adenomatosis in a foal. Vet Pathol 19:447-450, 1982.
8. ELMORE DB, ANDERSON JH, DIRD DW, SANDERS KD, LERCHE NW: Diarrhea rates and risk factors for developing chronic diarrhea in infant and juvenile rhesus monkeys. Lab Animal Sci 42(4):356-359, 1992.
9. ERIKSEN K, LANDSVERK T, BRATBERG B: Morphology and immunoperoxidase studies of intestinal adenomatosis in the blue fox, Alopex lagopus. J Comp Pathol 102:265-278, 1990.
10. FOX JG, LAWSON GK: Campylobacter-like omega intracellular antigen in proliferative colitis of ferrets. Lab Anim Sci 38:34-36, 1988.
11. FRISK CS, WAGNER JE, OWENS DR: Hamster enteritis: A review. Lab Animals 11:79-85, 1977.
12. Gebhart, CJ: Personal communication.
13. GEORGE JW, LERCHE NW: Electrolyte abnormalities associated with diarrhea in rhesus monkeys: 100 cases 1986-1987. JAVMA 196(10):1654-1658, 1990.
14. GIRARD C, LEMARCHAND T, HIGGINS R: Porcine colonic spirochetosis: A retrospective study of eleven cases. Can Vet J 36:291-294, 1995.
15. HEISE C, MILLER CJ, LACKNER A, DANDEKAR S: Primary acute simian immunodeficiency virus infection of intestinal lymphoid tissue is associated with gastrointestinal dysfunction. J Infect Dis 169(5): 1116-1120, 1994.
16. HEISE C, VOGEL P, MILLER CJ, HALSTED CH, DANDEKAR S: Simian immunodeficiency virus infection of the gastrointestinal tract of rhesus macaques. Functional, pathological and morphological changes. Am J Pathol 142(6):1759-1761, 1993.
17. HOLMBERG CA, HENRICKSON RV, MALAGA C, SCHNEIDER R, GRIBBLE D: Nontuberculous mycobacterial disease in rhesus monkeys. Vet Pathol 19(Suppl 7):9-16, 1982.
18. HOTCHKISS CE, SHAMES B, PERKINS SE, FOX JG: Proliferative enteropathy of rabbits: The intracellular Campylobacter-like organism is closely related to Lawsonia intracellularis. Lab Anim Sci 46:623-627, 1996.
19. JUBB KF, KENNEDY PC, PALMER N (eds): Pathology of Domestic Animals, 3rd edition, Vol 2. Orlando: Academic Press Inc., 1985
20. KNITTEL JP, JORDAN DM, SCHWARTZ KJ, JANKE BH, ROOF MB, MCORIST S, HARRIS DL: Evaluation of antemortem polymerase chain reaction and serologic methods for detection of Lawsonia intracellularis-exposed pigs. Am J Vet Res 59(6):722-726, 1998.
21. LACKNER AA, MOORE PF, MARX PA, MUNN RJ, GARDNER MB, LOWENSTINE LJ: Immunohistochemical localization of type D retrovirus serotype 1 in the digestive tract of rhesus monkeys with simian AIDS. J Med Primatol 19(3-4):339-349, 1990.
22. LEMARCHAND TX, TULLY JR TN, SHANE SM, DUNCAN DE: Intracellular Campylobacter-like organisms associated with rectal prolapse and proliferative enteroproctitis in emus Dromaius novaehollandiae. Vet Pathol 34:152-156, 1997.
23. MCORIST S, GEBHART CJ, LAWSON GK: Enterocyte proliferation and intracellular bacteria in animals. Gut 35(10):1483-1486, 1994.
24. MCORIST S, GEBHART CJ, BOID R, BARNS SM: Characterization of Lawsonia intracellularis gen. nov., sp. nov., the obligately intracellular bacterium of porcine proliferative enteropathy. Int J Sys Bacteriol 45(4):820-825, 1995.
25. MUTO T, NOGUCHI Y, SUZUKI K, ZAW KM: Adenomatous intestinal hyperplasia in guinea pigs associated with Campylobacter-like bacteria. Jpn J Med Sci Biol 36:337-342, 1983.
26. REINHARDT B, HOUSER WD, SADOFF DA, SCHEFFLER J, EISELE SG, HEMPEL MJ: Treatment of nonspecific diarrhea with metronidazole in rhesus macaques. J Med Primatol 16(5):311-316, 1987.
27. RUSSELL RG, DETOLLA LJ: Shigellosis. In: Nonhuman Primates II. Jones TC, Mohr U, Hunt RD (eds). Berlin: Springer-Verlag 46-53, 1993.
28. ROWLAND AC, LAWSON GK: Porcine proliferative enteropathies. In: Diseases of Swine, 7th edition. Leman AD, Straw BE, Mengeling WL, D'Allaire S, Taylor DJ (eds). Ames, IA: Iowa State University Press, 560-569, 1992.
29. STONE JD, HEISE CC, MILLER CJ, HALSTED CH, DANDEKAR S: Development of malabsorption and nutritional complications in simian immunodeficiency virus-infected rhesus macaques. AIDS 8(9): 1245-1256, 1994.
30. VANDENBERGHE J, VERHEYEN A, LAUWERS S, GEBOES K: Spontaneous adenocarcinoma of the ascending colon in Wistar rats: The intracytoplasmic presence of a Campylobacter-like bacterium. J Comp Pathol 95:45-55, 1985.
31. VANDENBERGHE J, HOORENS J: Campylobacter-species and regional enteritis in lambs. Rec Vet Sci 29:390-391, 1980.
32. WILLIAMS NM, HARRISON LR, GEBHART CJ: Proliferative enteropathy in a foal caused by Lawsonia intracellularis-like bacterium. J Vet Diag Invest 8(2):254-256, 1996.
33. WINKELMAN NL, DEE SD: Ileitis: An update. Comped Contin Educ Pract Vet 19:S19-S25, 1996.