메뉴 건너뛰기




Volumn 19, Issue 3, 1999, Pages 940-947

Prostaglandin E2 stimulates amyloid precursor protein gene expression: Inhibition by immunosuppressants

Author keywords

Astrocytes; cAMP; Cyclosporin A; FK506; Inflammation; Rapamycin

Indexed keywords

8 BROMO CYCLIC AMP; AMYLOID PRECURSOR PROTEIN; CYCLOHEXIMIDE; CYCLOSPORIN A; DACTINOMYCIN; FORSKOLIN; GLIAL FIBRILLARY ACIDIC PROTEIN; OKADAIC ACID; PROSTAGLANDIN E2; PROTEIN; RAPAMYCIN; TACROLIMUS; CYCLIC AMP; CYCLIC AMP DEPENDENT PROTEIN KINASE; CYCLOSPORIN; IMMUNOSUPPRESSIVE AGENT; MESSENGER RNA;

EID: 0033068185     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/jneurosci.19-03-00940.1999     Document Type: Article
Times cited : (76)

References (42)
  • 1
    • 0000293742 scopus 로고
    • Über eine eigenartige Erkrankung der Hirnrinde
    • Alzheimer A (1907) Über eine eigenartige Erkrankung der Hirnrinde. Allg Z Psychiatr Psychol-Gerichtl Med 64:146-148.
    • (1907) Allg Z Psychiatr Psychol-gerichtl Med , vol.64 , pp. 146-148
    • Alzheimer, A.1
  • 3
    • 0031032434 scopus 로고    scopus 로고
    • Enhanced expression of amyloid precursor protein in response to dibutyryl cyclic AMP is not mediated by the transcription factor AP-2
    • Bourbonniére M, Shekarabi M, Nalbantoglu J (1997) Enhanced expression of amyloid precursor protein in response to dibutyryl cyclic AMP is not mediated by the transcription factor AP-2. J Neurochem 68:909-916.
    • (1997) J Neurochem , vol.68 , pp. 909-916
    • Bourbonniére, M.1    Shekarabi, M.2    Nalbantoglu, J.3
  • 4
    • 0029006492 scopus 로고
    • Synapse loss and gliosis in the molecular layer of cerebral cortex in Alzheimer's disease and in frontal lobe degeneration
    • Brun A, Liu X, Erikson C (1995) Synapse loss and gliosis in the molecular layer of cerebral cortex in Alzheimer's disease and in frontal lobe degeneration. Neurodegeneration 4:171-177.
    • (1995) Neurodegeneration , vol.4 , pp. 171-177
    • Brun, A.1    Liu, X.2    Erikson, C.3
  • 6
    • 0028174973 scopus 로고
    • β-amyloid formation as a potential therapeutic target for Alzheimer's disease
    • Cordell B (1994) β-amyloid formation as a potential therapeutic target for Alzheimer's disease. Annu Rev Pharmacol Toxicol 34:69-89.
    • (1994) Annu Rev Pharmacol Toxicol , vol.34 , pp. 69-89
    • Cordell, B.1
  • 7
  • 9
    • 0029086681 scopus 로고
    • Specificity of expression and effects of eicosanoid mediators in normal physiology and human diseases
    • Goetzl EJ, An S, Smith WL (1995) Specificity of expression and effects of eicosanoid mediators in normal physiology and human diseases. FASEB J 9:1051-1058.
    • (1995) FASEB J , vol.9 , pp. 1051-1058
    • Goetzl, E.J.1    An, S.2    Smith, W.L.3
  • 10
    • 0025373986 scopus 로고
    • Expression of β amyloid protein precursor mRNAs: Recognition of a novel alternatively spliced form and quantitation in Alzheimer's disease using PCR
    • Golde TE, Estus S, Usiak M, Younkin LH, Younkin SG (1990) Expression of β amyloid protein precursor mRNAs: recognition of a novel alternatively spliced form and quantitation in Alzheimer's disease using PCR. Neuron 4:253-267.
    • (1990) Neuron , vol.4 , pp. 253-267
    • Golde, T.E.1    Estus, S.2    Usiak, M.3    Younkin, L.H.4    Younkin, S.G.5
  • 11
    • 0028801680 scopus 로고
    • Loss of synaptophysin-like immunoreactivity in the hippocampal formation is an early phenomenon in Alzheimer's disease
    • Heinonen O, Soininen H, Sorvari H, Kosunen O, Paljärvi L, Koivisto E, Riekkinen PJ (1995) Loss of synaptophysin-like immunoreactivity in the hippocampal formation is an early phenomenon in Alzheimer's disease. Neuroscience 64:375-384.
    • (1995) Neuroscience , vol.64 , pp. 375-384
    • Heinonen, O.1    Soininen, H.2    Sorvari, H.3    Kosunen, O.4    Paljärvi, L.5    Koivisto, E.6    Riekkinen, P.J.7
  • 12
    • 0029738333 scopus 로고    scopus 로고
    • β-adrenergic receptors regulate astrogliosis and cell proliferation in the central nervous system in vivo
    • Hodges-Savola C, Rogers SD, Ghilardi JR, Timm DR, Mantyh PW (1996) β-adrenergic receptors regulate astrogliosis and cell proliferation in the central nervous system in vivo. Glia 17:52-62.
    • (1996) Glia , vol.17 , pp. 52-62
    • Hodges-Savola, C.1    Rogers, S.D.2    Ghilardi, J.R.3    Timm, D.R.4    Mantyh, P.W.5
  • 14
    • 0024515832 scopus 로고
    • The formation of prostaglandins in the postmortem cerebral cortex of Alzheimer-type dementia patients
    • Iwamoto N, Kobayashi K, Kosaka K (1989) The formation of prostaglandins in the postmortem cerebral cortex of Alzheimer-type dementia patients. J Neurol 236:80-84.
    • (1989) J Neurol , vol.236 , pp. 80-84
    • Iwamoto, N.1    Kobayashi, K.2    Kosaka, K.3
  • 15
    • 0024445028 scopus 로고
    • 2-receptors in prefrontal cortex and hippocampus
    • 2-receptors in prefrontal cortex and hippocampus. J Neurochem 53:1772-1781. mcKametani F, Tanaka K, Ishii T, Ikeda S, Kennedy HE, Allsop D (1993) Secretory form of Alzheimer amyloid precursor protein 695 in human brain lacks β/A4 amyloid immunoreactivity. Biochem Biophys Res Commun 191:392-398.
    • (1989) J Neurochem , vol.53 , pp. 1772-1781
    • Kalaria, R.N.1    Andorn, A.C.2    Tabaton, M.3    Whitehouse, P.J.4    Harik, S.I.5    Unnerstall, J.R.6
  • 16
    • 0027202676 scopus 로고
    • Secretory form of Alzheimer amyloid precursor protein 695 in human brain lacks β/A4 amyloid immunoreactivity
    • 2-receptors in prefrontal cortex and hippocampus. J Neurochem 53:1772-1781. mcKametani F, Tanaka K, Ishii T, Ikeda S, Kennedy HE, Allsop D (1993) Secretory form of Alzheimer amyloid precursor protein 695 in human brain lacks β/A4 amyloid immunoreactivity. Biochem Biophys Res Commun 191:392-398.
    • (1993) Biochem Biophys Res Commun , vol.191 , pp. 392-398
    • McKametani, F.1    Tanaka, K.2    Ishii, T.3    Ikeda, S.4    Kennedy, H.E.5    Allsop, D.6
  • 17
    • 0029147583 scopus 로고
    • Amyloid precursor protein processing is stimulated by metabotropic glutamate receptors
    • Lee RKK, Wurtman RJ, Cox AJ, Nitsch RM (1995) Amyloid precursor protein processing is stimulated by metabotropic glutamate receptors. Proc Natl Acad Sci USA 92:8083-8087.
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 8083-8087
    • Lee, R.K.K.1    Wurtman, R.J.2    Cox, A.J.3    Nitsch, R.M.4
  • 18
    • 85088332253 scopus 로고    scopus 로고
    • 2 stimulates overexpression of amyloid precursor protein in astrocyte cultures: Inhibition by immunosuppressants
    • 2 stimulates overexpression of amyloid precursor protein in astrocyte cultures: inhibition by immunosuppressants. J Neurochem [Suppl] 69:S103B.
    • (1997) J Neurochem [Suppl] , vol.69
    • Lee, R.K.K.1    Knapp, S.2    Zarach, J.3    Wurtman, R.J.4
  • 19
    • 0030924310 scopus 로고    scopus 로고
    • Stimulation of amyloid precursor protein synthesis by adrenergic receptors coupled to cAMP formation
    • Lee RKK, Araki W, Wurtman RJ (1997b) Stimulation of amyloid precursor protein synthesis by adrenergic receptors coupled to cAMP formation. Proc Natl Acad Sci USA 94:5422-5426.
    • (1997) Proc Natl Acad Sci USA , vol.94 , pp. 5422-5426
    • Lee, R.K.K.1    Araki, W.2    Wurtman, R.J.3
  • 20
    • 0029816659 scopus 로고    scopus 로고
    • Cellular functions of immunophilins
    • Marks AR (1996) Cellular functions of immunophilins. Physiol Rev 76:631-649.
    • (1996) Physiol Rev , vol.76 , pp. 631-649
    • Marks, A.R.1
  • 21
    • 0019313317 scopus 로고
    • Preparation of separate astroglial and oligodendroglial cell cultures from rat cerebral tissue
    • McCarthy KD, de Vellis J (1980) Preparation of separate astroglial and oligodendroglial cell cultures from rat cerebral tissue. J Cell Biol 85:890-902.
    • (1980) J Cell Biol , vol.85 , pp. 890-902
    • McCarthy, K.D.1    De Vellis, J.2
  • 22
    • 0029610011 scopus 로고
    • The inflammatory response system of brain: Implications for therapy of Alzheimer and other neurodegenerative diseases
    • McGeer P, McGeer EG (1995) The inflammatory response system of brain: implications for therapy of Alzheimer and other neurodegenerative diseases. Brain Res Rev 21:195-218.
    • (1995) Brain Res Rev , vol.21 , pp. 195-218
    • McGeer, P.1    McGeer, E.G.2
  • 23
    • 0026476297 scopus 로고
    • Release of Alzheimer amyloid precursor derivatives stimulated by activation of muscarinic acetylcholine receptors
    • Nitsch RM, Slack BE, Wurtman RJ, Growdon JH (1992) Release of Alzheimer amyloid precursor derivatives stimulated by activation of muscarinic acetylcholine receptors. Science 258:304-307.
    • (1992) Science , vol.258 , pp. 304-307
    • Nitsch, R.M.1    Slack, B.E.2    Wurtman, R.J.3    Growdon, J.H.4
  • 24
    • 0030248270 scopus 로고    scopus 로고
    • Microglial cells internalize aggregates of the Alzheimer's disease amyloid β-protein via a scavenger receptor
    • Paresce DM, Ghosh RN, Maxfield FR (1996) Microglial cells internalize aggregates of the Alzheimer's disease amyloid β-protein via a scavenger receptor. Neuron 17:553-565.
    • (1996) Neuron , vol.17 , pp. 553-565
    • Paresce, D.M.1    Ghosh, R.N.2    Maxfield, F.R.3
  • 25
    • 0028239893 scopus 로고
    • RAFT1: A mammalian protein that binds to FKBP12 in a rapamycin-dependent fashion and is homologous to yeast TORs
    • Sabatini DM, Erdjument-Bromage H, Lui M, Tempst P, Snyder SH (1994) RAFT1: a mammalian protein that binds to FKBP12 in a rapamycin-dependent fashion and is homologous to yeast TORs. Cell 78:35-43.
    • (1994) Cell , vol.78 , pp. 35-43
    • Sabatini, D.M.1    Erdjument-Bromage, H.2    Lui, M.3    Tempst, P.4    Snyder, S.H.5
  • 27
    • 0028988020 scopus 로고
    • 2+-dependent phosphatase calcineurin in gene transcription that is stimulated by cAMP through cAMP response elements
    • 2+-dependent phosphatase calcineurin in gene transcription that is stimulated by cAMP through cAMP response elements. J Biol Chem 270:8860-8866.
    • (1995) J Biol Chem , vol.270 , pp. 8860-8866
    • Schwaninger, M.1    Blume, R.2    Krüger, M.3    Lux, G.4    Oetjen, E.5    Knepel, W.6
  • 28
    • 0001067847 scopus 로고
    • β-amyloid precursor protein of Alzheimer disease occurs as 110- to 135-kilodalton membrane associated proteins in neural and nonneuronal tissues
    • Selkoe DJ, Podlisny MB, Joachim CL, Vickers EA, Lee G, Fritz LC, Oltersdorf T (1988) β-amyloid precursor protein of Alzheimer disease occurs as 110-to 135-kilodalton membrane associated proteins in neural and nonneuronal tissues. Proc Natl Acad Sci USA 85:7341-7345.
    • (1988) Proc Natl Acad Sci USA , vol.85 , pp. 7341-7345
    • Selkoe, D.J.1    Podlisny, M.B.2    Joachim, C.L.3    Vickers, E.A.4    Lee, G.5    Fritz, L.C.6    Oltersdorf, T.7
  • 29
    • 0031024889 scopus 로고    scopus 로고
    • Transcriptional regulation of amyloid precursor protein during dibutyryl cyclic AMP-induced differentiation of NG108-15 cells
    • Shekarabi M, Bourbonniere M, Dagenais A, Nalbantoglu J (1997) Transcriptional regulation of amyloid precursor protein during dibutyryl cyclic AMP-induced differentiation of NG108-15 cells. J Neurochem 68:970-978.
    • (1997) J Neurochem , vol.68 , pp. 970-978
    • Shekarabi, M.1    Bourbonniere, M.2    Dagenais, A.3    Nalbantoglu, J.4
  • 30
    • 0024723475 scopus 로고
    • Expression of β-amyloid precursor protein in reactive astrocytes following neuronal damage
    • Siman R, Card JP, Nelson RB, Davis LG (1989) Expression of β-amyloid precursor protein in reactive astrocytes following neuronal damage. J Neurosci 3:275-285.
    • (1989) J Neurosci , vol.3 , pp. 275-285
    • Siman, R.1    Card, J.P.2    Nelson, R.B.3    Davis, L.G.4
  • 31
    • 0025373508 scopus 로고
    • Evidence that β-amyloid protein in Alzheimer's disease is not derived by normal processing
    • Sisodia SS, Koo EH, Beyreuther K, Unterbeck A, Price D (1990) Evidence that β-amyloid protein in Alzheimer's disease is not derived by normal processing. Science 248:492-495.
    • (1990) Science , vol.248 , pp. 492-495
    • Sisodia, S.S.1    Koo, E.H.2    Beyreuther, K.3    Unterbeck, A.4    Price, D.5
  • 32
    • 0028935040 scopus 로고
    • Tyrosine phosphorylation-dependent stimulation of amyloid precursor protein secretion by the m3 muscarinic acetylcholine receptor
    • Slack BE, Breu J, Petryniak MA, Srivastava K, Wurtman RJ (1995) Tyrosine phosphorylation-dependent stimulation of amyloid precursor protein secretion by the m3 muscarinic acetylcholine receptor. J Biol Chem 270:8337-8344.
    • (1995) J Biol Chem , vol.270 , pp. 8337-8344
    • Slack, B.E.1    Breu, J.2    Petryniak, M.A.3    Srivastava, K.4    Wurtman, R.J.5
  • 33
    • 0028059841 scopus 로고
    • Expression of a ubiquitous, cross-reactive homologue of the mouse β-amyloid precursor protein (APP)
    • Slunt HH, Thinakaran G, Koch C, Lo ACY, Tanzi RE, Sisodia SS (1994) Expression of a ubiquitous, cross-reactive homologue of the mouse β-amyloid precursor protein (APP). J Biol Chem 269:2637-2644.
    • (1994) J Biol Chem , vol.269 , pp. 2637-2644
    • Slunt, H.H.1    Thinakaran, G.2    Koch, C.3    Lo, A.C.Y.4    Tanzi, R.E.5    Sisodia, S.S.6
  • 34
    • 0027393439 scopus 로고
    • Increased levels of the kunitz protease inhibitor-containing βAPP mRNAs in rat brain following neurotoxic damage
    • Solá C, Garcia-Ladona FJ, Mengod G, Probst A, Frey P, Palacios JM (1993) Increased levels of the Kunitz protease inhibitor-containing βAPP mRNAs in rat brain following neurotoxic damage. Mol Brain Res 17:41-52.
    • (1993) Mol Brain Res , vol.17 , pp. 41-52
    • Solá, C.1    Garcia-Ladona, F.J.2    Mengod, G.3    Probst, A.4    Frey, P.5    Palacios, J.M.6
  • 35
    • 0030975605 scopus 로고    scopus 로고
    • Neurotrophic actions of nonimmunosuppressive analogues of immunosuppressive drugs FK506, rapamycin and cyclosporin A
    • Steiner JP, Connolly MA, Valentine HL, Hamilton GS, Dawson TM, Hester L, Snyder SH (1997) Neurotrophic actions of nonimmunosuppressive analogues of immunosuppressive drugs FK506, rapamycin and cyclosporin A. Nat Med 3:421-428.
    • (1997) Nat Med , vol.3 , pp. 421-428
    • Steiner, J.P.1    Connolly, M.A.2    Valentine, H.L.3    Hamilton, G.S.4    Dawson, T.M.5    Hester, L.6    Snyder, S.H.7
  • 37
    • 0025334082 scopus 로고
    • Autopsy samples of Alzheimer's cortex show increased peroxidation in vitro
    • Subbarao KV, Richardson JS, Ang LC (1990) Autopsy samples of Alzheimer's cortex show increased peroxidation in vitro. J Neurochem 55:342-345.
    • (1990) J Neurochem , vol.55 , pp. 342-345
    • Subbarao, K.V.1    Richardson, J.S.2    Ang, L.C.3
  • 38
    • 0024847273 scopus 로고
    • Tissue-specific expression of three types of β-protein precursor mRNA: Enhancement of protease inhibitor-harboring types in Alzheimer's disease brains
    • Tanaka S, Shiojiri S, Takahashi Y, Kitaguchi N, Ito H, Kameyama M, Kimura J, Nakamura S, Ueda K (1989) Tissue-specific expression of three types of β-protein precursor mRNA: enhancement of protease inhibitor-harboring types in Alzheimer's disease brains. Biochem Biophys Res Commun 165:1406-1414.
    • (1989) Biochem Biophys Res Commun , vol.165 , pp. 1406-1414
    • Tanaka, S.1    Shiojiri, S.2    Takahashi, Y.3    Kitaguchi, N.4    Ito, H.5    Kameyama, M.6    Kimura, J.7    Nakamura, S.8    Ueda, K.9
  • 39
    • 0030974065 scopus 로고    scopus 로고
    • Metabotropic glutamate receptor agonists increase release of soluble amyloid precursor protein derivatives from rat brain cortical and hippocampal slices
    • Ulus IH, Wurtman RJ (1997) Metabotropic glutamate receptor agonists increase release of soluble amyloid precursor protein derivatives from rat brain cortical and hippocampal slices. J Pharmacol Exp Ther 281:149-154.
    • (1997) J Pharmacol Exp Ther , vol.281 , pp. 149-154
    • Ulus, I.H.1    Wurtman, R.J.2
  • 40
    • 0029782171 scopus 로고    scopus 로고
    • Glial fibrillary acidic protein in the cerebrospinal fluid of patients with dementia
    • Wallin A, Blennow K, Rosengren LE (1996) Glial fibrillary acidic protein in the cerebrospinal fluid of patients with dementia. Dementia 7:267-272.
    • (1996) Dementia , vol.7 , pp. 267-272
    • Wallin, A.1    Blennow, K.2    Rosengren, L.E.3
  • 41
    • 0024550204 scopus 로고
    • Identification, biogenesis and localization of precursors of Alzheimer's disease A4 amyloid protein
    • Weidemann A, König G, Bunke D, Fischer P, Salbaum JM, Masters CL, Beyreuther K (1989) Identification, biogenesis and localization of precursors of Alzheimer's disease A4 amyloid protein. Cell 57:115-126.
    • (1989) Cell , vol.57 , pp. 115-126
    • Weidemann, A.1    König, G.2    Bunke, D.3    Fischer, P.4    Salbaum, J.M.5    Masters, C.L.6    Beyreuther, K.7
  • 42
    • 0026779680 scopus 로고
    • Degeneration in vitro of post-mitotic neurons overexpressing the Alzheimer amyloid protein precursor
    • Yoshikawa K, Aizawa T, Hayashi Y (1992) Degeneration in vitro of post-mitotic neurons overexpressing the Alzheimer amyloid protein precursor. Nature 359:64-67.
    • (1992) Nature , vol.359 , pp. 64-67
    • Yoshikawa, K.1    Aizawa, T.2    Hayashi, Y.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.