ACCURACY;
ANALYTIC METHOD;
BINDING KINETICS;
COMPETITIVE INHIBITION;
CONCENTRATION RESPONSE;
CONFERENCE PAPER;
DRUG BINDING SITE;
DRUG DETERMINATION;
DRUG RECEPTOR BINDING;
DRUG SPECIFICITY;
DRUG SYNTHESIS;
FLUORESCENCE;
INTERMETHOD COMPARISON;
PROTEIN DETERMINATION;
RECEPTOR AFFINITY;
Primary structure and functional expression of the 5HT3 receptor, a serotonin-gated ion channel
Maricq A. V., Peterson A. S., Brake A. J., Myers R. M., Julius D. Primary structure and functional expression of the 5HT3 receptor, a serotonin-gated ion channel. Science 1991; 254: 432 – 437
Reversible oriented surface immobilization of functional proteins on oxide surfaces
Schmid E. L., Keller T. A., Dienes Z., Vogel H. Reversible oriented surface immobilization of functional proteins on oxide surfaces. Anal. Chem. 1997; 69: 1979 – 1985
Expression of ligand-gated ion channels with the Semliki forest virus expression system
Lundström K., Michel A., Blasey H., Bernard A. R., Hovius R., Vogel H., Surprenant A. Expression of ligand-gated ion channels with the Semliki forest virus expression system. J. Recept. Signal Transduct. Res. 1997; 17: 115 – 126
Large scale application of the Semliki Forest virus system: 5-HT3 receptor production
(Tours) (in press)
Blasey H. D., Brethon B., Hovius R., Lundström K., Rey L., Vogel H., Tairi A.-P., Bernard A. R. Large scale application of the Semliki Forest virus system: 5-HT3 receptor production. ESACT Proceedings 1997, (Tours) (in press)
Characterization of a mouse serotonin 5-HT3 receptor purified from mammalian cells
Hovius R., Tairi A. P., Blasey H., Bernard A., Lundstrom K., Vogel H. Characterization of a mouse serotonin 5-HT3 receptor purified from mammalian cells. J. Neurochem. 1998; 70: 824 – 834
Relationship between the inhibition constant (Kj) and the concentration of inhibitor which causes 50 per cent inhibition (IC50) of an enzymatic reaction
Cheng Y., Prusoff W. H. Relationship between the inhibition constant (Kj) and the concentration of inhibitor which causes 50 per cent inhibition (IC50) of an enzymatic reaction. Biochemical Pharmacology 1973; 22: 3099 – 3108
Screening ligands for membrane protein receptors by total internal reflection fluorescence: the 5-HT3 serotonin receptor
Schmid E. L., Tairi A. P., Hovius R., Vogel H. Screening ligands for membrane protein receptors by total internal reflection fluorescence: the 5-HT3 serotonin receptor. Anal. Chem. 1998; 70: 1331 – 1338