Screening ligands for membrane protein receptors by total internal reflection fluorescence: The 5-HT3 serotonin receptor

Analytical Chemistry

Volumn 70, Issue 7, 1998, Pages 1331-1338

  Schmid, Evelyne L ^a   Tairi, Ana Paula ^a   Hovius, Ruud ^a   Vogel, Horst ^a  

^a EPFL   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

3 (5 METHYL 1H IMIDAZOL 4 YL) 1 (1 METHYL 1H INDOL 3 YL) 1 PROPANONE; GR 186741X; GRANISETRON; LIGAND; MEMBRANE RECEPTOR; ONDANSETRON; SEROTONIN 3 RECEPTOR; UNCLASSIFIED DRUG;

ARTICLE; BINDING COMPETITION; DRUG RECEPTOR BINDING; DRUG SCREENING; FLUORESCENCE; LIGAND BINDING; RECEPTOR AFFINITY;

ANIMALS; BINDING, COMPETITIVE; DRUG DESIGN; ION CHANNELS; KINETICS; LIGANDS; QUARTZ; RECEPTORS, CELL SURFACE; RECEPTORS, SEROTONIN; RECEPTORS, SEROTONIN, 5-HT3; SPECTROMETRY, FLUORESCENCE;

EID: 0032055436     PISSN: 00032700     EISSN: None     Source Type: Journal    
DOI: 10.1021/ac9712658     Document Type: Article

References (29)

1. Plowman, T. E.; Reichert, W. M.; Peters, C. R.; Wang, H. K.; Christensen, D. A.; Herron, J. N. Biosens. Bioelectron. 1996, 11, 149-160.
2. Proceedings of the 2nd International Symposium on Miniaturized Total Analysis Systems; Widmer, H. M, Verpoorte, E., Barnard S., Eds.; AMI: Basel, 1996.
3. Hamon, M. Central and peripheral 5-HT3 receptors; Academic Press: London, 1992.
4. Sui, S.; Urumow, T.; Sackmann, E. Biochemistry 1988, 27, 7463-7469.
5. Poglitsch, C. L.; Sumner, M. T.; L.Thompson, N. Biochemistry 1991, 30, 6662-6671.
6. Hsieh, H. V.; Thompson, N. L. Biochemistry 1995, 34, 12481-12488.
7. Rogers, K. R.; Valdes, J. J.; Eldefrawi, M. E. Anal. Biochem. 1989, 182, 353-359.
8. Rogers, K. R.; Valdes, J. J.; Eldefrawi, M. E. Biosens. Bioelectron. 1991, 6, 1-8.
9. Rogers, K. R.; Eldefrawi, M. E.; Menking, D. E.; Thompson, R G.; Valdes, J. J. Biosens. Bioelectron. 1991, 6, 507-516.
10. Downer, N. W.; Li, J.; Penniman, E. M.; DeLuca, L. W.; Smith, H. G. Biosens. Bioelectron. 1992, 7, 429-440.
11. Puu, G.; Gustafson, I.; Artursson, E.; Ohlsson, P. Biosens. Bioelectron. 1995, 10, 463-476.
12. Taylor, R F.; Marenchic, I. G.; Cook, E. J. Anal. Chim. Acta 1988, 213, 131-138.
13. Schmid, E. L.; Keller, T. A.; Dienes, Z.; Vogel, H. Anal. Chem. 1997, 69, 1979-1985.
14. Hovius, R.; Tairi, A.-P.; Blasey, H.; Bernard, A.; Lundström, K.; Vogel, H. J. Neurochem. 1998, 70, 824-834.
15. Boess, F. G.; Beroukhim, R.; Martin, I. L. J. Neurochem. 1995, 64, 1401-1405.
16. Schmidt, A. M.; Müller, H. N.; Skerra, A. Chem. Biol. 1996, 3, 645-653.
17. Tairi, A.; Hovius, R.; Vogel, H., manuscript in preparation.
18. 19 to the present ligand - receptor system, confirmed the ligand-binding isotherms quantitatively.
19. Duveneck, G.; Pawlak, M.; Neuschäfer, D.; Budach, W.; Ehrat, M. SPIE Proc. 1996, 2928, 98-109.
20. Yakel, J. L.; Lagurtta, A.; Adelman, J. P.; North, R. A. Proc. Natl. Acad. Sci. U.S.A. 1993, 90, 5030-5033.
21. Hope, A. G.; Downie, D. L.; Sutherland, L.; Lambert, J. J.; Peters, J. A.; Burchell, B. Eur. J. Pharmacol. 1993, 245, 187-192.
22. Bonhaus, D. W.; Stefanich, E.; Loury, D. N.; Hsu, S. A. O.; Eglen, R. M.; Wong, E. H. F. J. Neurochem. 1995, 65, 104-110.
23. Duschl, C.; Sévin-landais, A.-F.; Vogel, H. Biophys. J. 1996, 70, 1985-1995.
24. Shuck, P. Annu. Rev. Biophys. Biomol. Struct. 1997, 26, 541-566.
25. Cheng, Y. C.; Prusoff, W. H. Biochem. Pharmacol. 1973, 22, 3099-3108.
26. Bolanos, F. J.; Schechter, L. E.; Miquel, M. C.; Emerit, M. B.; Rumigny, J. F.; Hamon, M.; Gozlan, H. Biochem. Pharmacol. 1990, 40, 1541-1550.
27. Keller, T. A.; Duschl, C.; Kröger, D.; Sévin-Landais, A.-F.; Vogel, H.; Cervigni, S. E.; Dummy, P. Supramol. Sci. 1995, 2, 155-160.
28. Heyse, S.; Ernst, O. P.; Dienes, Z.; Hofmann, K.-P.; Vogel, H. Biochemistry 1998, 37, 507-522.
29. Laporte, A. M.; Koscielniak, T.; Ponchant M.; Vergé, D.; Hamon, M.; Gozlan, H. Synapse 1992, 10, 271-281.