-
1
-
-
0020570451
-
Inhibition of drug metabolism by β-adrenoceptor antagonists
-
Bax N.D.S., Lennard M.S., Al Asady S., Deacon C.S., Tucker G.T. Inhibition of drug metabolism by β-adrenoceptor antagonists. Drugs. 25(Suppl 2):1983;121-126.
-
(1983)
Drugs
, vol.25
, Issue.SUPPL. 2
, pp. 121-126
-
-
Bax, N.D.S.1
Lennard, M.S.2
Al Asady, S.3
Deacon, C.S.4
Tucker, G.T.5
-
2
-
-
0018864363
-
Calcium antagonistic drugs. Mechanism of action
-
Church J., Zsoter T. Calcium antagonistic drugs. Mechanism of action. Can. J. Physiol. Pharmacol. 58:1980;254-264.
-
(1980)
Can. J. Physiol. Pharmacol.
, vol.58
, pp. 254-264
-
-
Church, J.1
Zsoter, T.2
-
3
-
-
0019183307
-
Effect of metoprolol and propranolol on theophyline elimination
-
Conrad K.A., Nyman D.W. Effect of metoprolol and propranolol on theophyline elimination. Clin. Pharm. Ther. 28:1980;463-467.
-
(1980)
Clin. Pharm. Ther.
, vol.28
, pp. 463-467
-
-
Conrad, K.A.1
Nyman, D.W.2
-
4
-
-
0023007788
-
Combination therapy with beta adrenoceptor blockers and calcium antagonists
-
Dargie H.L. Combination therapy with beta adrenoceptor blockers and calcium antagonists. Br. J. Clin. Pharmacol. 21:1986;1555-1605.
-
(1986)
Br. J. Clin. Pharmacol.
, vol.21
, pp. 1555-1605
-
-
Dargie, H.L.1
-
5
-
-
0025827496
-
Pharmacokinetics of diltiazem and propranolol when administered alone and in combination
-
Dimmitt D., Yu D., Elvin A., Giesing D. Pharmacokinetics of diltiazem and propranolol when administered alone and in combination. Biopharm. Drug Dispos. 1:1991;515-523.
-
(1991)
Biopharm. Drug Dispos.
, vol.1
, pp. 515-523
-
-
Dimmitt, D.1
Yu, D.2
Elvin, A.3
Giesing, D.4
-
6
-
-
0027438563
-
Regio- And stereoselective propranolol metabolism by 15 forms of purified cytochromes P-450 from rat liver
-
Fujita S., Umeda S., Funae Y., Imaoka S., Abe H., Ishida R., Adachi T., Masuda A., Kazusaka A., Suzuki T. Regio- and stereoselective propranolol metabolism by 15 forms of purified cytochromes P-450 from rat liver. J. Pharmacol. Exp. Ther. 264:1993;226-233.
-
(1993)
J. Pharmacol. Exp. Ther.
, vol.264
, pp. 226-233
-
-
Fujita, S.1
Umeda, S.2
Funae, Y.3
Imaoka, S.4
Abe, H.5
Ishida, R.6
Adachi, T.7
Masuda, A.8
Kazusaka, A.9
Suzuki, T.10
-
7
-
-
0001818451
-
Microsomal enzymes involved in toxicology. Analysis and separation
-
A.W. Hayes. New York: Raven Press
-
Guengerich F.P. Microsomal enzymes involved in toxicology. Analysis and separation. Hayes A.W. Principles and methods of toxicology. 1982;609-634 Raven Press, New York.
-
(1982)
Principles and Methods of Toxicology
, pp. 609-634
-
-
Guengerich, F.P.1
-
8
-
-
0022998708
-
Characterization of rat and human liver microsomal cytochrome P-450 forms involved in nifedipine oxidation, a prototype for genetic polymorphism in oxidative drug metabolism
-
Guengerich F.P., Martin M.V., Beaune P.H., Kremers P., Wolff T., Waxman D. Characterization of rat and human liver microsomal cytochrome P-450 forms involved in nifedipine oxidation, a prototype for genetic polymorphism in oxidative drug metabolism. J. Biol. Chem. 261:1986;5051.
-
(1986)
J. Biol. Chem.
, vol.261
, pp. 5051
-
-
Guengerich, F.P.1
Martin, M.V.2
Beaune, P.H.3
Kremers, P.4
Wolff, T.5
Waxman, D.6
-
9
-
-
0025860978
-
Oxidation of dihydropyridine calcium channel blockers and analogues by human liver cytochrome P-450IIIA4
-
Guengerich F.P., Brian W.R., Iwasaki M., Sari M., Baarnhielm C., Bartsson P. Oxidation of dihydropyridine calcium channel blockers and analogues by human liver cytochrome P-450IIIA4. J. Med. Chem. 34:1991;1838-1844.
-
(1991)
J. Med. Chem.
, vol.34
, pp. 1838-1844
-
-
Guengerich, F.P.1
Brian, W.R.2
Iwasaki, M.3
Sari, M.4
Baarnhielm, C.5
Bartsson, P.6
-
10
-
-
0025359380
-
Effects of calcium channel blockers on the pharmacokinetics of propranolol stereoisomers
-
Hunt B.A., Bottorff M.B., Herring V.L. Effects of calcium channel blockers on the pharmacokinetics of propranolol stereoisomers. Clin. Pharmacol. Ther. 47:1990;584-591.
-
(1990)
Clin. Pharmacol. Ther.
, vol.47
, pp. 584-591
-
-
Hunt, B.A.1
Bottorff, M.B.2
Herring, V.L.3
-
11
-
-
0026769890
-
Induction of propranolol metabolism by the azo dye sudan III in rats
-
Ishida R., Obara S., Masubuchi Y., Narimatsu S., Fujita S., Suzuki T. Induction of propranolol metabolism by the azo dye sudan III in rats. Biochem. Pharmacol. 41:1992;2489-2492.
-
(1992)
Biochem. Pharmacol.
, vol.41
, pp. 2489-2492
-
-
Ishida, R.1
Obara, S.2
Masubuchi, Y.3
Narimatsu, S.4
Fujita, S.5
Suzuki, T.6
-
12
-
-
0000971001
-
Effect of propranolol, pindolol and atenolol on drug-metabolizing enzyme systems after single administration in rats
-
Kastelova A., Stoytchev Ts. Effect of propranolol, pindolol and atenolol on drug-metabolizing enzyme systems after single administration in rats. Compt. Rend. Acad. Bulg. Sci. 46:1993;119-122.
-
(1993)
Compt. Rend. Acad. Bulg. Sci.
, vol.46
, pp. 119-122
-
-
Kastelova, A.1
Stoytchev, Ts.2
-
13
-
-
0002603445
-
Effect of nifedipine, verapamil and diltiazem on drug-metabolizing enzyme systems after single sdministration in rats
-
Koleva M., Stoytchev Ts. Effect of nifedipine, verapamil and diltiazem on drug-metabolizing enzyme systems after single sdministration in rats. Compt. Rend. Acad. Bulg. Sci. 44:1991;109-111.
-
(1991)
Compt. Rend. Acad. Bulg. Sci.
, vol.44
, pp. 109-111
-
-
Koleva, M.1
Stoytchev, Ts.2
-
14
-
-
0023915881
-
Pharmacokinetic and pharmacodynamic interactions between nisoldipine and propranolol
-
Levin M., Ogilvie R., Leenen F. Pharmacokinetic and pharmacodynamic interactions between nisoldipine and propranolol. Clin. Pharmacol. Ther. 43:1988;39-48.
-
(1988)
Clin. Pharmacol. Ther.
, vol.43
, pp. 39-48
-
-
Levin, M.1
Ogilvie, R.2
Leenen, F.3
-
15
-
-
0025168996
-
Identification of the rabbit and human cytochromes P-450IIIA as the major enzymes involved in the N-demethylation of diltiazem
-
Lydiane P., Gillet G., Fabre I., Dalet-Beluche I., Bonfils C., Thenor J.P., Maurel P. Identification of the rabbit and human cytochromes P-450IIIA as the major enzymes involved in the N-demethylation of diltiazem. Drug Metab. Dispos. 18:1990;711-719.
-
(1990)
Drug Metab. Dispos.
, vol.18
, pp. 711-719
-
-
Lydiane, P.1
Gillet, G.2
Fabre, I.3
Dalet-Beluche, I.4
Bonfils, C.5
Thenor, J.P.6
Maurel, P.7
-
16
-
-
0026031356
-
Impairtment of debrisoquine 4-hydroxylase and related monooxygenase activities in the rat following treatment with propranolol
-
Masubuchi Y., Fujita S., Chiba M., Kugimato N., Umeda S., Suzuki T. Impairtment of debrisoquine 4-hydroxylase and related monooxygenase activities in the rat following treatment with propranolol. Biochem. Pharmacol. 41:1991;861-865.
-
(1991)
Biochem. Pharmacol.
, vol.41
, pp. 861-865
-
-
Masubuchi, Y.1
Fujita, S.2
Chiba, M.3
Kugimato, N.4
Umeda, S.5
Suzuki, T.6
-
17
-
-
0026508625
-
A possible mechanism of the impairtment of hepatic microsomal monooxigenase activities after multiple administration of propranolol in rats
-
Masubuchi Y., Suzuki K., Fujita S., Suzuki T. A possible mechanism of the impairtment of hepatic microsomal monooxigenase activities after multiple administration of propranolol in rats. Biochem. Pharmacol. 43(4):1992;757-762.
-
(1992)
Biochem. Pharmacol.
, vol.43
, Issue.4
, pp. 757-762
-
-
Masubuchi, Y.1
Suzuki, K.2
Fujita, S.3
Suzuki, T.4
-
18
-
-
0027500823
-
Regioselective contributionof the cytochrome P-450 2D subfamily to propranolol metabolism in rat liver microsomes
-
Masubuchi Y., Kagimoto N., Narimatsu S., Fujita S., Suzuki T. Regioselective contributionof the cytochrome P-450 2D subfamily to propranolol metabolism in rat liver microsomes. Drug Metab. Dispos. 21(6):1993;1012-1016.
-
(1993)
Drug Metab. Dispos.
, vol.21
, Issue.6
, pp. 1012-1016
-
-
Masubuchi, Y.1
Kagimoto, N.2
Narimatsu, S.3
Fujita, S.4
Suzuki, T.5
-
19
-
-
0028020099
-
Cytochrome P-450 isozymes involved in propranolol metabolism in human liver microsomes. The role of CYP2D6 as ring-hydroxilase and CYP1A2 as N-desisopropylase
-
Masubuchi Y., Hosokawa S., Horie T., Suzuki T., Ohmori S., Kitada M., Narimatsu S. Cytochrome P-450 isozymes involved in propranolol metabolism in human liver microsomes. The role of CYP2D6 as ring-hydroxilase and CYP1A2 as N-desisopropylase. Drug Metab. Dispos. 22(6):1994b;909-915.
-
(1994)
Drug Metab. Dispos.
, vol.22
, Issue.6
, pp. 909-915
-
-
Masubuchi, Y.1
Hosokawa, S.2
Horie, T.3
Suzuki, T.4
Ohmori, S.5
Kitada, M.6
Narimatsu, S.7
-
20
-
-
0027985788
-
Role of the CYP2D subfamily in metabolism-dependent covalent binding of propranolol to liver microsomal protein in rats
-
Masubuchi Y., Narimatsu S., Hosokawa S., Suzuki T. Role of the CYP2D subfamily in metabolism-dependent covalent binding of propranolol to liver microsomal protein in rats. Biochem. Pharmacol. 48(10):1994a;1891-1898.
-
(1994)
Biochem. Pharmacol.
, vol.48
, Issue.10
, pp. 1891-1898
-
-
Masubuchi, Y.1
Narimatsu, S.2
Hosokawa, S.3
Suzuki, T.4
-
21
-
-
0003009327
-
Experiments illustrating drug metabolism in vitro. Determination of aniline hydroxylase
-
B.H. La Du, H.G. Mandel, & E.L. Way. Baltimore: Williams and Williams
-
Mazel P. Experiments illustrating drug metabolism in vitro. Determination of aniline hydroxylase. La Du B.H., Mandel H.G., Way E.L. Fundamentals of drug metabolism and drug disposition. 1972;569-572 Williams and Williams, Baltimore.
-
(1972)
Fundamentals of Drug Metabolism and Drug Disposition
, pp. 569-572
-
-
Mazel, P.1
-
22
-
-
0030572727
-
Cytochrome P-450 enzymes involved in the enchancement of propranolol N-desisopropilation after repeated administration of propranolol in rats
-
Narimatsu S., Monchida M., Matsumoto T., Masubuchi Y., Horie T., Nagata K., Funae Y., Cho A.K., Suzuki T. Cytochrome P-450 enzymes involved in the enchancement of propranolol N-desisopropilation after repeated administration of propranolol in rats. Chem.-Biol. Interact. 101(3):1996;207-224.
-
(1996)
Chem.-Biol. Interact.
, vol.101
, Issue.3
, pp. 207-224
-
-
Narimatsu, S.1
Monchida, M.2
Matsumoto, T.3
Masubuchi, Y.4
Horie, T.5
Nagata, K.6
Funae, Y.7
Cho, A.K.8
Suzuki, T.9
-
23
-
-
0029056763
-
Characterization of a chemically reactive propranolol metabolite that binds to microsomal proteins of rat liver
-
Narimatsu S., Watanabe T., Masubuchi Y., Horie T., Kumagai Y., Cho A.K., Imaoka S., Funae Y., Ishikawa T., Suzuki T. Characterization of a chemically reactive propranolol metabolite that binds to microsomal proteins of rat liver. Chem. Res. Toxicol. 8(5):1995;721-728.
-
(1995)
Chem. Res. Toxicol.
, vol.8
, Issue.5
, pp. 721-728
-
-
Narimatsu, S.1
Watanabe, T.2
Masubuchi, Y.3
Horie, T.4
Kumagai, Y.5
Cho, A.K.6
Imaoka, S.7
Funae, Y.8
Ishikawa, T.9
Suzuki, T.10
-
24
-
-
0001072638
-
The colorimetric estimation of formaldehyde by means of the Hantzch reaction
-
Nash T. The colorimetric estimation of formaldehyde by means of the Hantzch reaction. J. Biol. Chem. 55:1953;412-416.
-
(1953)
J. Biol. Chem.
, vol.55
, pp. 412-416
-
-
Nash, T.1
-
25
-
-
0024268446
-
Regiochemistry and enantioselectivity in the oxidative N-dealkylation of verapamil
-
Nelson W., Olsen N. Regiochemistry and enantioselectivity in the oxidative N-dealkylation of verapamil. Drug Metab. Dispos. 16:1988;834-841.
-
(1988)
Drug Metab. Dispos.
, vol.16
, pp. 834-841
-
-
Nelson, W.1
Olsen, N.2
-
26
-
-
78651165715
-
The carbon monooxide binding pigment of liver microsomes. I. Evidence for its hemoprotein nature
-
Omura T., Sato R. The carbon monooxide binding pigment of liver microsomes. I. Evidence for its hemoprotein nature. J. Biol. Chem. 239:1964;2370-2378.
-
(1964)
J. Biol. Chem.
, vol.239
, pp. 2370-2378
-
-
Omura, T.1
Sato, R.2
-
27
-
-
0024972124
-
Combined beta adrenergic and calcium entry blockade in angina pectoris
-
Parker M. Combined beta adrenergic and calcium entry blockade in angina pectoris. New Engl. J. Med. 320:1989;709.
-
(1989)
New Engl. J. Med.
, vol.320
, pp. 709
-
-
Parker, M.1
-
28
-
-
0021825310
-
Inhibition of hepatic microsomal drug metabolism by the calcium channel blockers diltiazem and verapamil
-
Renton K. Inhibition of hepatic microsomal drug metabolism by the calcium channel blockers diltiazem and verapamil. Biochem. Pharmacol. 34:1985;2549-2553.
-
(1985)
Biochem. Pharmacol.
, vol.34
, pp. 2549-2553
-
-
Renton, K.1
-
29
-
-
0019362164
-
The inhibitory effect of propranolol pretreatment on its own metabolism in rats
-
Scheneck D.W., Pritchared J.F. The inhibitory effect of propranolol pretreatment on its own metabolism in rats. J. Pharmacol. Exp. Ther. 218:1981;575-581.
-
(1981)
J. Pharmacol. Exp. Ther.
, vol.218
, pp. 575-581
-
-
Scheneck, D.W.1
Pritchared, J.F.2
-
30
-
-
0019488290
-
Hepatic calcium efflux during cytochrome P-450 dependent drug oxidation at the endoplasmatic reticulum in intact liver
-
Sies H., Graf P., Estrela J. Hepatic calcium efflux during cytochrome P-450 dependent drug oxidation at the endoplasmatic reticulum in intact liver. Proc. Natl. Acad. Sci. USA. 78:1981;3358-3362.
-
(1981)
Proc. Natl. Acad. Sci. USA
, vol.78
, pp. 3358-3362
-
-
Sies, H.1
Graf, P.2
Estrela, J.3
-
31
-
-
0027419514
-
Kinetic analysis of mutual metabolic inhibition of lidocaine and propranolol in rat liver microsomes
-
Suzuki T., Ishida R., Matsui S., Narimatsu S. Kinetic analysis of mutual metabolic inhibition of lidocaine and propranolol in rat liver microsomes. Biochem. Pharmacol. 45(7):1993;1528-1530.
-
(1993)
Biochem. Pharmacol.
, vol.45
, Issue.7
, pp. 1528-1530
-
-
Suzuki, T.1
Ishida, R.2
Matsui, S.3
Narimatsu, S.4
-
32
-
-
0024562199
-
Effect of diltiazem on the pharmacokinetics of propranolol, metoprolol and atenolol
-
Tateishi T., Nakashima H., Shitou T., Kumagai Y., Ohashi K, Hosoda S., Ebihara A. Effect of diltiazem on the pharmacokinetics of propranolol, metoprolol and atenolol. Eur. J. Clin. Pharmacol. 36:1989;67-70.
-
(1989)
Eur. J. Clin. Pharmacol.
, vol.36
, pp. 67-70
-
-
Tateishi, T.1
Nakashima, H.2
Shitou, T.3
Kumagai, Y.4
Ohashi, K.5
Hosoda, S.6
Ebihara, A.7
-
33
-
-
0017801794
-
Purifed liver microsomal NADPH-cytochrome P-450 reductase
-
Vermilion J., Coon M. Purifed liver microsomal NADPH-cytochrome P-450 reductase. J. Biol. Chem. 253:1978;2694-2704.
-
(1978)
J. Biol. Chem.
, vol.253
, pp. 2694-2704
-
-
Vermilion, J.1
Coon, M.2
-
34
-
-
0024268983
-
Interaction between propranolol and calcium channel blockers in cardiac and vascular smooth muscle
-
Weishaar R.E., Quade M.M., Pugsley T.A., Shih Y.H., Taylor D.G. Interaction between propranolol and calcium channel blockers in cardiac and vascular smooth muscle. J. Mol. Cell. Cardiol. 20:1988;897.
-
(1988)
J. Mol. Cell. Cardiol.
, vol.20
, pp. 897
-
-
Weishaar, R.E.1
Quade, M.M.2
Pugsley, T.A.3
Shih, Y.H.4
Taylor, D.G.5
-
35
-
-
0024463403
-
Propranolol induced alterations in rat erythrocyte membrabne fluidity and apparent phase-transition temperatutes
-
Weitman S.D., Phelan A.M., Lech J.J., Lange D.G. Propranolol induced alterations in rat erythrocyte membrabne fluidity and apparent phase-transition temperatutes. Biochem. Pharmacol. 38:1989;2949-2954.
-
(1989)
Biochem. Pharmacol.
, vol.38
, pp. 2949-2954
-
-
Weitman, S.D.1
Phelan, A.M.2
Lech, J.J.3
Lange, D.G.4
-
36
-
-
0021993327
-
Separate and combined effects of nadolol and nifedipine on the cardiac response to exercise
-
Wilkins M., Woods K., Jack D., Kendall M., Laugher S. Separate and combined effects of nadolol and nifedipine on the cardiac response to exercise. Eur. J. Clin. Pharmacol. 28:1985;113-117.
-
(1985)
Eur. J. Clin. Pharmacol.
, vol.28
, pp. 113-117
-
-
Wilkins, M.1
Woods, K.2
Jack, D.3
Kendall, M.4
Laugher, S.5
-
37
-
-
0029671251
-
Roles of cytochrome b5 in the oxidation of testosterone and nifedipine by recombinant cytochrome P-450 3A4 and by human liver microsomes
-
Yamazaki H., Nakano M., Imai Y., Ueng Y., Guengerich F., Shimada T. Roles of cytochrome b5 in the oxidation of testosterone and nifedipine by recombinant cytochrome P-450 3A4 and by human liver microsomes. Arch. Biochem. Biophys. 2:1996;174-182.
-
(1996)
Arch. Biochem. Biophys.
, vol.2
, pp. 174-182
-
-
Yamazaki, H.1
Nakano, M.2
Imai, Y.3
Ueng, Y.4
Guengerich, F.5
Shimada, T.6
-
38
-
-
0028956887
-
Identification of human CYP isoforms involved in the metabolism of propranolol enantiomers - N-desisopropylation is mediated mainly by CYP1A2
-
Yoshimoto K., Echizen H., Chiba K., Tahi M., Ishizaki T. Identification of human CYP isoforms involved in the metabolism of propranolol enantiomers - N-desisopropylation is mediated mainly by CYP1A2. Br. J. Clin. Pharmacol. 39(4):1995;421-431.
-
(1995)
Br. J. Clin. Pharmacol.
, vol.39
, Issue.4
, pp. 421-431
-
-
Yoshimoto, K.1
Echizen, H.2
Chiba, K.3
Tahi, M.4
Ishizaki, T.5
|