New therapeutics from a dairy byproduct - Cheese whey

Drug Development Research

Volumn 46, Issue 3-4, 1999, Pages 286-291

  Regester, Geoffrey O ^a   Belford, David A ^a  

^a CHILD HEALTH RESEARCH INSTITUTE   (Australia)

Author keywords

Cheese whey; Chronic wounds; Growth factors; Oral mucosa

Indexed keywords

ANTIINFECTIVE AGENT; GROWTH FACTOR;

ANIMAL EXPERIMENT; ANTIMICROBIAL ACTIVITY; ARTICLE; CELL PROLIFERATION; CHEESE; DIGESTIVE SYSTEM INJURY; DRUG USE; MUCOSA INFLAMMATION; NONHUMAN; SYRIAN HAMSTER; WHEY; WOUND; WOUND HEALING;

EID: 0033063214     PISSN: 02724391     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1098-2299(199903/04)46:3/4<286::AID-DDR14>3.0.CO;2-6     Document Type: Article

References (27)

1. Baker SR, Stacey MC, Jopp McKay AG, Hoskin SE, Thompson PJ. 1991. Epidemiology of venous ulcers. Br J Surg 78:864-867.
2. Belford DA, Rogers M, Regester GO, Francis GL, Smithers GW, Liepe IJ, Priebe IK, Ballard FJ. 1995. Milk-derived growth factors as serum supplements for the growth of fibroblast and epithelia cells. In Vitro Cell Dev Biol 31:750-758.
3. Belford DA, Rogers ML, Francis GL, Payne C, Ballard FJ, Goddard C. 1997. Platelet-derived growth factor, insulin-like growth factors, fibroblast growth factors and transforming growth factor beta do not account for the cell growth activity present in bovine milk. J Endocrinol 154(1):45-55.
4. Bennet NT, Schultz GS. 1993. Growth factors and wound healing. II. Role in normal and chronic wound healing. Am J Surg 166:74-81.
5. Capiaumont J, Legrand C, Dousset B, Parmentelot I, Linden G, Belleville F, Nabet P. 1994. Whey and β-lactoglobulin: milk byproducts that can replace fetal calf serum in mouse hybridoma cell culture. Lait 74:127-137.
6. Donovan SM, Odle J. 1994. Growth factors in milk as mediators of infant development. Annu Nutr Rev 14:147-167.
7. Farrel CL, Bready JV, Rex KL, Chen JN, DiPalma CR, Whitcomb KL, Yin S, Hill DC, Weimann B, Starnes CO, Havill AM, Lu ZN, Aukerman SL, Pierce GF, Thomason A, Potten CS, Ulich TR, Lacey DL. 1998. Keratinocyte growth factor protects mice from chemotherapy and radiation-induced gastrointestinal injury and mortality. Cancer Res 58:1-7.
8. Francis GL, Regester GO, Webb HA, Ballard FJ. 1995. Extraction from cheese whey by cation-exchange chromatography of factors that stimulate the growth of mammalian cells. J Dairy Sci. 78:1209-1218.
9. Francis GL, Goddard C, Belford DA, Walton PE, Regester GO, DeSilva K, Copeland A, Smithers GW, Toneman L, Ballard FJ. 1996. A potent growth factor supplement for cell culture purified from whey. In: Carrondo MJT, Griffiths B, Moreira JLP, editors. Animal cell technology: from vaccines to genetic medicine.Dordrecht, Boston & London: Kluwer Academic Publishers. p 721-724.
10. Grosvenor CE, Picciano MF, Baumrucker CR. 1993. Hormones and growth factors in milk. Endocrinol Rev 14:710-728.
11. Guimont C, Marchall E, Giradet JM, Linden G. 1997. Biologically active factors in bovine milk and dairy byproducts: influence on cell culture. Crit Rev Food Sci and Nutr 37(4):393-410.
12. Howarth GS, Francis GL, Cool JC, Xu X, Byard RW, Read LC. 1996. Milk growth factors enriched from cheese whey ameliorate intestinal damage by methotrexate when administered orally to rats. J Nutr 126:2519-2530.
13. Kannan V, Bapsy PP, Anantha N. 1997. Efficacy and safety of granulocyte macrophage-colony stimulating factor (GM-CSF) on the frequency and severity of radiation mucositis in patients with head and neck carcinoma. Int J Rad Oncol Biol and Phys 37(5): 1005-1010.
14. MacDonald RS, Thornton WH Jr, Marshall RT. 1994. A cell culture to identify biologically active peptides generated by bacterial hydrolysis of casein. J Dairy Sci 77:1167-1175.
15. MacLellan DG. 1994. Chronic leg ulceration: the hidden epidemic. Med J Austr 161:619-621.
16. Moulti-Mati F, Mati A, Capiaumont J, Belleville F, Linden G, Nabet P. 1991. Role de la b-lactoglobuline dans l'active proliferative du lactoserum. Lait. 71:543-553.
17. Pakkanen R, Aalto J. 1997. Growth factors and antimicrobial factors of bovine colostrum. Int Dairy J. 7:285-297.
18. Rayner TE, Cowin AJ, Cooter RD, Belford DA. 1997. Wound strength is returned to normal levels in steroid-compromised rats by treatment with milk-derived growth factors. Fifth Annual Meeting of the Wound Healing Society, Nashville, Tennessee, Wound Repair and Regeneration 5(1)A122.
19. Ramirez OT, Sureshkumar GK, Mutharasan R. 1989. Bovine colostrum or milk as serum substitute for the cultivation of a mouse hybridoma. Biotechnol Bioeng 35:882-889.
20. Rogers ML, Belford DA, Francis GL, Ballard FJ. 1995a. Identification of fibroblast growth factors in bovine cheese whey. J Dairy Res 62:501-507.
21. Rogers ML, Goddard C, Regester CO, Ballard FJ, Belford DA. 1995b. Transforming growth factor beta in bovine milk: concentration, stability and molecular mass forms. J Endocrinol 151(1):77-86.
22. Schams D. 1994. Growth factors in milk. Endocr Rev 28:3-8.
23. Shing YW, Klagsbrun M. 1984. Human and bovine milk contain different sets of growth factors. Endocrinology 115(1):273-282.
24. Sonis ST, Lindquist L, Van Vugt A. 1994. Prevention of chemotherapy-induced ulcerative mucositis by transforming growth factor-β3. Cancer Res 54:1135-1138.
25. Sonis ST, Van Vugt AG, McDonald J, Dotoli E, Schwertschlag U, Szklut P, Keith J. 1997a. Mitigating effects of interleukin 11 on consecutive courses of 5-fluourouracil-induced ulcerative mucositis in hamsters. Cytokine 9(8):605-612.
26. Sonis ST, Van Vugt AG, Brien JPO. 1997b. Transforming growth factor-β3 mediated modulation of cell cycling and attenuation of 5-fluorouracil induced oral mucositis. Oral Oncol 33:47-54.
27. Watson DL, Francis GL, Ballard FJ. 1992. Factors in ruminant colostrum that influence cell growth and murine IgE antibody responses. J Dairy Res 59:369-380.