Hypertensive left ventricular remodeling and ACE-gene polymorphism

Cardiovascular Research

Volumn 43, Issue 1, 1999, Pages 192-199

  Perticone, Francesco ^a   Maio, Raffaele ^a   Cosco, Carmela ^a   Ceravolo, Roberto ^a   Iacopino, Saverio ^a   Chello, Massimo ^a   Mastroroberto, Pasquale ^a   Tramontano, Donatella ^a   Mattioli, Pier L ^a  

^a Policlin Mater Domini Via T C ^*  (Italy)

Author keywords

ACE gene polymorphism; Cardiac remodeling; Cardiovascular risk factors; Hypertension; Left ventricular hypertrophy

Indexed keywords

ACETYL COENZYME A;

ADULT; ALLELE; ARTICLE; CARDIOVASCULAR RISK; FEMALE; GENE DELETION; GENE FREQUENCY; GENETIC POLYMORPHISM; GENOTYPE; HEART LEFT VENTRICLE ENDDIASTOLIC VOLUME; HEART LEFT VENTRICLE HYPERTROPHY; HEART LEFT VENTRICLE MASS; HEART STRESS; HEART VENTRICLE REMODELING; HUMAN; HYPERTENSION; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL;

AGE FACTORS; ANALYSIS OF VARIANCE; EVALUATION STUDIES; FEMALE; GENOTYPE; HUMANS; HYPERTENSION; LINEAR MODELS; MALE; MIDDLE AGED; PEPTIDYL-DIPEPTIDASE A; POLYMORPHISM, GENETIC; RISK FACTORS; SEX FACTORS; VENTRICULAR REMODELING;

EID: 0033062831     PISSN: 00086363     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0008-6363(99)00055-3     Document Type: Article

References (33)

1. Koren M.J., Devereux R.B., Casale P.N., Savage D.D., Laragh J.H. Relation of left ventricular mass and geometry to morbidity and mortality in uncomplicated essential hypertension. Ann Intern Med. 114:1991;345-352.
2. Levy D., Garrison R.J., Savage D.D., Kannel W.B., Castelli W.P. Prognostic implications of echocardiographically determined left ventricular mass in the Framingham Heart Study. New Engl J Med. 322:1990;1561-1566.
3. Verdecchia P., Porcellati C., Zampi I., et al. Asymmetric left ventricular remodeling due to isolated septal thickening in patients with systemic hypertension and normal left ventricular masses. Am J Cardiol. 73:1994;247-252.
4. Ganau A., Devereux R.B., Roman M.J., et al. Patterns of left ventricular hypertrophy and geometric remodeling in essential hypertension. J Am Coll Cardiol. 19:1992;1550-1558.
5. Devereux R.B., Savage D.D., Sachs I., Laragh J.H. Relation of hemodynamic load to left ventricular hypertrophy and performance in hypertension. Am J Cardiol. 51:1983;171-176.
6. Campus S., Malavasi A., Ganau A. Systolic function of the hypertrophied left ventricle. J Clin Hypertens. 3:1987;79-87.
7. De Simone G., Di Lorenzo L., Costantino G., Moccia D., Buonissimo S., De Devitiis O. Supernormal contractility in primary hypertension without left ventricular hypertrophy. Hypertension. 11:1988;457-463.
8. De Simone G., Di Lorenzo L., Moccia D., Costantino G., Buonissimo S., De Devitiis O. Hemodynamic hypertrophied left ventricular patterns in systemic hypertension. Am J Cardiol. 60:1987;1317-1321.
9. Soubrier F., Alhenc-Gelas F., Hubert C., et al. Two putative active centers in human angiotensin I-converting enzyme revealed by molecular cloning. Proc Natl Acad Sci USA. 85:1988;9386-9390.
10. Rigat B., Hubert C., Alhenc-Gelas F., Cambien F., Corvol P., Saubrier F. An insertion/deletion polymorphism in the angiotensin I converting enzyme gene accounting for half the variance of serum enzyme levels. J Clin Invest. 86:1990;1343-1346.
11. Harrap S.B., Davidson H.R., Connor J.M., et al. The angiotensin I converting enzyme gene and predisposition to high blood pressure. Hypertension. 21:1993;455-460.
12. Cambien F., Poirier O., Lecerf L., et al. Deletion polymorphism in the gene for angiotensin-converting enzyme is a potent risk factor for myocardial infarction. Nature. 359:1992;641-644.
13. Raynolds M.V., Bristow M.R., Bush E.W., et al. Angiotensin-converting enzyme DD genotype in patients with ischaemic or idiopathic dilated cardiomyopathy. Lancet. 342:1993;1073-1075.
14. Marian A.J., Yu Q-T., Workman R., Greve G., Roberts R. Angiotensin-converting enzyme polymorphism in hypertrophic cardiomyopathy and sudden cardiac death. Lancet. 342:1993;1085-1086.
15. Schunkert H., Hense H-V., Holmer S.R., et al. Association between a deletion polymorphism of the angiotensin-converting enzyme gene and left ventricular hypertrophy. New Engl J Med. 330:1994;1634-1638.
16. Iwai N., Ohmichi N., Nakamura Y., Kinoshita M. DD genotype of the angiotensin-converting enzyme gene is a risk factor for left ventricular hypertrophy. Circulation. 90:1994;2622-2628.
17. Perticone F., Ceravolo R., Cosco C., et al. Deletion polymorphism of angiotensin-converting enzyme gene and left ventricular hypertrophy in southern Italian patients. J Am Coll Cardiol. 29:1997;365-369.
18. Staessen J.A., Wang J.G., Ginocchio G., et al. The deletion/insertion polymorphism of the angiotensin converting enzyme gene and cardiovascular-renal risk. J Hypertens. 15:1997;1579-1592.
19. Lindpainter K., Lee M., Larson M.G., et al. Absence of association or genetic linkage between the angiotensin-converting enzyme gene and left ventricular mass. New Engl J Med. 334:1996;1023-1028.
20. Yamada Y., Ichihara S., Fujimura T., Yokata M. Lack of association of polymorphisms of the angiotensin converting enzyme and angiotensin genes with nonfamilial hypertrophic or dilated cardiomyopathy. Am J Hypertens. 10:1997;921-928.
21. Lindpainter K., Pfeffer M.A., Kreutz R., et al. A prospective evaluation of an angiotensin-converting-enzyme gene polymorphism and the risk of ischemic heart disease. New Engl J Med. 332:1995;706-711.
22. Sahn D.J., De Maria A., Kissler J., Wyman A. The committee on M-mode standardization of the American Society of Echocardiography: recommendation regarding quantification in M-mode echocardiography; results of a survey of echocardiographic measurement. Circulation. 58:1978;1072-1080.
23. Devereux R.B., Reichek N. Echocardiographic determination of left ventricular mass in man. Anatomic evaluation of the method. Circulation. 55:1977;613-618.
24. Rigat B., Hubert C., Corvol P., Soubrier F. PCR detection of the insertion/deletion polymorphism of the human angiotensin converting enzyme gene (DCP1) (dipeptidyl carboxypeptidase1). Nucl Acids Res. 20:1992;1443.
25. Shanmugam V., Sell K.W., Saha B.K. Mistyping ACE heterozygotes. 3:1993;120-121 Cold Spring Harbor Laboratory.
26. Zingone A., Dominijanni A., Mele E., et al. Deletion polymorphism in the gene for angiotensin converting enzyme is associated with elevated fasting blood glucose levels. Hum Genet. 94:1994;207-209.
27. O'Donnel C.J., Lindpaintner K., Martin G.L., et al. Evidence for association and genetic linkage of the angiotensin-converting enzyme locus with hypertension and blood pressure in men but not women in the Framingham heart study. Circulation. 97:1998;1766-1772.
28. Gharavi A.G., Lipkowitz M.S., Diamond J.A., Jhang J.S., Phillips R.A. Deletion polymorphism of the angiotensin-converting enzyme gene is independently associated with left ventricular mass and geometric remodeling in systemic hypertension. Am J Cardiol. 77:1996;1315-1319.
29. Montgomery H.E., Clarkson P., Dollery C.M., et al. Association of angiotensin-converting enzyme gene I/D polymorphism with change in left ventricular mass in response to physical training. Circulation. 96:1997;741-747.
30. Sen S., Bumbus F.M. Collagen synthesis in development and reversal of cardiac hypertrophy in spontaneously hypertensive rats. Am J Cardiol. 44:1979;954-958.
31. Pardo-Mindàn F.J., Panizo A. Alterations in the extracellular matrix of the myocardium in essential hypertension. Eur Heart J. 14:1993;12-14.
32. Lee Y.A., Lindpainter K. Roler of the cardiac renin-angiotensin system in hypertensive cardiac hypertrophy. Eur Heart J. 14:1993;42-48.
33. Jeurremaitre X., Lifton R.P., Hunt S.C., Williams R.R., Lalonel J.M. Absence of linkage between the angiotensin converting enzyme locus and human essential hypertension. Nat Genet. 1:1992;72-75.