Deletion polymorphism of angiotensin-converting enzyme gene and left ventricular hypertrophy in southern Italian patients

Journal of the American College of Cardiology

Volumn 29, Issue 2, 1997, Pages 365-369

  Perticone, Francesco ^a,b   Ceravolo, Roberto ^a   Cosco, Carmela ^a   Trapasso, Maria ^a   Zingone, Adriana ^a   Malatesta, Paola ^a   Perrotti, Nicola ^a   Tramontano, Donatella ^a   Mattioli, Pier L ^a  

^a UNIVERSITY MEDITERRANEA OF REGGIO CALABRIA   (Italy)

^b Policlinico Mater Domini   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

DIPEPTIDYL CARBOXYPEPTIDASE;

ADULT; AGED; ARTICLE; BLOOD PRESSURE MONITORING; FEMALE; GENETIC POLYMORPHISM; GENOTYPE; HEART LEFT VENTRICLE HYPERTROPHY; HEART LEFT VENTRICLE MASS; HUMAN; HYPERTENSION; ITALY; MAJOR CLINICAL STUDY; MALE; PATHOGENESIS; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; RENIN ANGIOTENSIN ALDOSTERONE SYSTEM;

ADULT; AGED; ECHOCARDIOGRAPHY; FEMALE; GENE DELETION; GENOTYPE; HUMANS; HYPERTENSION; HYPERTROPHY, LEFT VENTRICULAR; ITALY; MALE; MIDDLE AGED; PEPTIDYL-DIPEPTIDASE A; POLYMORPHISM, GENETIC;

EID: 0031020704     PISSN: 07351097     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0735-1097(96)00485-8     Document Type: Article

References (28)

1. Caulfield M, Lavander P, Farrall M, et al. Linkage of the angiotensinogen gene to essential hypertension. N Engl J Med 1994;330:1629-33.
2. Ward R. Familial aggregation and genetic epidemiology of blood pressure. In: Laragh JH, Brenner BM, editors. Hypertension: Pathophysiology, Diagnosis, and Management, vol 1. New York: Raven Press, 1990:81-100.
3. Pickering G. Hyperpiesis: high blood-pressure without evident cause: essential hypertension. BMJ 1965;2:1021-26.
4. Soubrier F, Alhenc-Gelas F, Hubert C, et al. Two putative active centers in human angiotensin I-converting enzyme revealed by molecular cloning. Proc Natl Acad Sci USA 1988;85:9386-90.
5. Rigat B, Hubert C, Alhenc-Gelas F, Cambien F, Corvol P, Saubrier F. An insertion/deletion polymorphism in the angiotensin I converting enzyme gene accounting for half the variance of serum enzyme levels. J Clin Invest 1990;86:1343-6.
6. Harrap SB, Davidson HR, Connor JM, et al. The angiotensin I converting enzyme gene and predisposition to high blood pressure. Hypertension 1993;21:455-60.
7. Cambien F, Poirier O, Lecerf L, et al. Deletion polymorphism in the gene for angiotensin-converting enzyme is a potent risk factor for myocardial infarction. Nature 1992;359:641-4.
8. Raynolds MV, Bristow MR, Bush EW, et al. Angiotensin-converting enzyme DD genotype in patients with ischaemic or idiopathic dilated cardiomyopathy. Lancet 1993;342:1073-5.
9. Marian AJ, Yu Q-T, Workman R, Greve G, Roberts R. Angiotensin-converting enzyme polymorphism in hypertrophic cardiomyopathy and sudden cardiac death. Lancet 1993;342:1085-6.
10. Levy D, Anderson KM, Savage DD, Kannel WB, Christiansen JC, Castelli WP. Echocardiographically detected left ventricular hypertrophy: prevalence and risk factors: the Framingham Heart Study. Ann Intern Med 1988;108: 7-13.
11. Clark S, Fowlies S, Coats A, et al. Ambulatory blood pressure monitoring: Validation of the TM 2420 according to the AAMI recommendation. J Hum Hypertens 1991;5:77-82.
12. White WB, Pickering TG, Morganroth J, et al. A multicenter evaluation of the A&D TM-2420 ambulatory blood pressure recorder. Am J Hypertens 1991;4:890-6.
13. Sahn DJ, De Maria A, Kissler J, Weyman A. The Committee on M-Mode Standardization of the American Society of Echocardiography: recommendation regarding quantification in M-mode echocardiography; results of a survey of echocardiographic measurement. Circulation 1978;58:1072-80.
14. Devereux RB, Reichek N. Echocardiographic determination of left ventricular mass in man: anatomic evaluation of the method. Circulation 1977;55: 613-8.
15. Rigat B, Hubert C, Corvol P, Soubrier F. PCR detection of the insertion/deletion polymorphism of the human angiotensin converting enzyme gene (DCP1) (dipeptidyl carboxypeptidasel). Nucl Acid Res 1992;20:1443.
16. Zingone A, Dominijanni A, Mele E, et al. Deletion polymorphism in the gene for angiotensin converting enzyme is associated with elevated fasting blood glucose levels. Hum Genet 1994;94:207-9.
17. Arbustini E, Grasso M, Fasani R, et al. Angiotensin converting enzyme gene deletion allele is independently and strongly associated with coronary atherosclerosis and myocardial infarction. Br Heart J 1995;74:584-591.
18. Schunkert H, Hense H-V, Holmer SR, et al. Association between a deletion polymorphism of the angiotensin-converting enzyme gene and left ventricular hypertrophy. N Engl J Med 1994;330:1634-8.
19. Devereux RB, Lutas EM, Casale PN, et al. Standardization of M-mode echocardiographic left ventricular anatomic measurements. J Am Coll Cardiol 1984;4:1222-30.
20. Iwai N, Ohmichi N, Nakamura Y, Kinoshita M. DD genotype of the angiotensin-converting enzyme gene is a risk factor for left ventricular hypertrophy. Circulation 1994;90:2622-8.
21. Kupari M, Perola M, Koskinen P, Virolainen J, Karhunen PJ. Left ventricular size, mass, and function in relation to angiotensin-converting enzyme gene polymorphism in humans. Am J Physiol 1994;267:H1107-11.
22. Lindpaintner K, Lee M, Larson MG, et al. Absence of association or genetic linkage between the angiotensin-converting-enzyme gene and left ventricular mass. N Engl J Med 1996;334:1023-8.
23. Lechin M, Quiñones MA, Omran A, et al. Angiotensin-I converting enzyme genotypes and left ventricular hypertrophy in patients with hypertrophic cardiomyopathy. Circulation 1995;92:1808-12.
24. Linz W, Wiemer G, Scholkens BA. Contribution of bradykinin to the cardiovascular effects of ramipril. J Cardiovasc Pharmacol 1993;22 Suppl 9:S1-S8.
25. Rousseau A, Michaud A, Chauvet MT, Lenfant M, Corvol P. The hemo-regulatory peptide N-acetyl-Ser-Asp-Lys-Pro is a natural and specific substrate of the N-terminal active site of human angiotensin-converting enzyme. J Biol Chem 1995;270:3656-61.
26. Dzau VJ. Local expression and pathophysiological role of renin-angiotensin in the blood vessels and heart. Basic Res Cardiol 1993;88 Suppl 1:1-14.
27. Katwa LC; Ratajaska A, Cleutjens JP, et al. Angiotensin converting enzyme and kininase-II-like activities in cultured valvular interstitial cell of the rat heart. Cardiovasc Res 1995;29:57-64.
28. Brilla CG, Maisch B. Regulation of the structural remodelling of the myocardium: from hypertrophy to heart failure. Eur Heart J 1994;15 Suppl D:45-52.