Fentanyl inhibits metabolism of midazolam: Competitive inhibition of CYP3A4 in vitro

British Journal of Anaesthesia

Volumn 82, Issue 6, 1999, Pages 900-903

  Oda, Y ^a   Mizutani, K ^a   Hase, I ^a   Nakamoto, T ^a   Hamaoka, N ^a   Asada, A ^a  

^a OSAKA CITY UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

Analgesics opioid, fentanyl; Enzymes, cytochrome P450; Hypnotics benzodiazepine, midazolam; Metabolism, midazolam

Indexed keywords

CYTOCHROME P450 ISOENZYME; FENTANYL; MIDAZOLAM;

ARTICLE; COMPETITIVE INHIBITION; CONTROLLED STUDY; DRUG HYDROXYLATION; DRUG METABOLISM; HUMAN; HUMAN CELL; INTRAVENOUS DRUG ADMINISTRATION; LIVER MICROSOME; MICHAELIS CONSTANT; PRIORITY JOURNAL;

EID: 0033062463     PISSN: 00070912     EISSN: None     Source Type: Journal    
DOI: 10.1093/bja/82.6.900     Document Type: Article

References (20)

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