Antigenic characterization and cytolocalization of P35, the major Mycoplasma penetrans antigen

Microbiology

Volumn 145, Issue 2, 1999, Pages 343-355

  Neyrolles, Olivier ^a,c   Eliane, Jean Pierre ^a   Ferris, Stéphane ^a   Ayr Florio Da Cunha, Regina ^a,d   Prevost, Marie Christine ^a   Bahraoui, Elmostafa ^b   Blanchard, Alain ^a  

^a INSTITUT PASTEUR   (France)

^b UNIVERSITÉ DE TOULOUSE   (France)

^c IMPERIAL COLLEGE SCHOOL OF MEDICINE   (United Kingdom)

^d UNIVERSITY OF SÃO PAULO   (Brazil)

Author keywords

Epitope mapping; Immunogenicity; Lipoprotein; Mycoplasma penetrans

Indexed keywords

BACTERIAL ANTIGEN; EPITOPE;

AMINO TERMINAL SEQUENCE; ANTIGENICITY; ARTICLE; CARBOXY TERMINAL SEQUENCE; ENZYME LINKED IMMUNOSORBENT ASSAY; EPITOPE MAPPING; ESCHERICHIA COLI; IMMUNOELECTRON MICROSCOPY; IMMUNOREACTIVITY; MYCOPLASMA; NONHUMAN; PRIORITY JOURNAL; WESTERN BLOTTING;

EID: 0033060730     PISSN: 13500872     EISSN: None     Source Type: Journal    
DOI: 10.1099/13500872-145-2-343     Document Type: Article

References (49)

1. Adam, T., Arpin, M., Prevost, M. C., Gounon, P. & Sansonetti, P. J. (1995). Cytoskeletal rearrangements and the functional role of T-plastin during entry of Shigella flexneri into HeLa cells. J Cell Biol 129, 367-381.
2. Andreev, J., Borovsky, Z., Rosenshine, I. & Rottem, S. (1995). Invasion of HeLa cells by Mycoplasma penetrans and the induction of tyrosine phosphorylation of a 145 kDa host cell protein. FEMS Microbiol Lett 132, 189-194.
3. Antoni, G., dal Maso, G., Berti, B., Soldatini, C. & Cocola, F. (1996). Detection of antigenic determinants in the Treponema pallidum membrane protein TmpA using overlapping synthetic peptides. J Immunol Methods 189, 137-140.
4. Arnon, R. & Van Regenmortel, M. H. (1992). Structural basis of antigenic specificity and design of new vaccines. FASEB J 6, 3265-3274.
5. Berzofsky, J. A. (1985). Intrinsic and extrinsic factors in protein antigenic structure. Science 229, 932-940.
6. Blanchard, A. (1997). Mycoplasmas and HIV infection, a possible interaction through immune activation. Wien Klin Wochenschr 109, 590-593.
7. Blanchard, A. & Montagnier, L. (1994). AIDS-associated mycoplasmas. Annu Rev Microbiol 48, 687-712.
8. Blanchard, A., Montagnier, L. & Gougeon, M. L. (1997). Influence of microbial infections on the progression of HIV disease. Trends Microbiol 5, 326-331.
9. Brenner, C., Neyrolles, O. & Blanchard, A. (1996). Mycoplasmas and HIV infection: from epidemiology to their interaction with immune cells. Front Biosci 1, 42-54.
10. Chou, P. Y. & Fasman, G. D. (1978). Empirical predictions of protein conformation. Annu Rev Biochem 47, 251-276.
11. Erdile, L. F., Brandt, M. A., Warakomski, D. J., Westrack, G. J., Sadziene, A., Barbour, A. G. & Mays, J. P. (1993). Role of attached lipid in immunogenicity of Borrelia burgdorferi OspA. Infect Immun 61, 81-90.
12. Ferris, S., Watson, H. L., Neyrolles, O., Montagnier, L. & Blanchard, A. (1995). Characterization of a major Mycoplasma penetrans lipoprotein and of its gene. FEMS Microbiol Lett 130, 313-319.
13. Fritz, R. B., Skeen, M. J., Chou, C. H., Garcia, M. & Egorov, I. K. (1985). Major histocompatibility complex-linked control of the murine immune response to myelin basic protein. J Immunol 134, 2328-2332.
14. Garbe, T., Harris, D., Vordermeier, M., Lathigra, R., Ivanyi, J. & Young, D. (1993). Expression of the Mycobacterium tuberculosis 19 kilodalton antigen in Mycobacterium smegmatis: immunological analysis and evidence of glycosylation. Infect Immun 61, 260-267.
15. Garnier, J., Osguthorpe, D. J. & Robson, B. (1978). Analysis of the accuracy and implications of simple methods for predicting the secondary structure of globular proteins. J Mol Biol 120, 97-120.
16. Geysen, H. M., Rodda, S. J., Mason, T. J., Tribbick, G. & Schoofs, P. G. (1987). Strategies for epitope analysis using peptide synthesis. J Immunol Methods 102, 259-274.
17. Giron, J. A., Lange, M. & Baseman, J. B. (1996). Adherence, fibronectin binding, and induction of cytoskeleton reorganization in cultured human cells by Mycoplasma penetrans. Infect Immun 64, 3419-3424.
18. Gorochov, G., Neumann, A. U., Kereveur, A. & 7 other authors (1998). Perturbation of CD4+ and CD8+ T-cell repertoires during progression to AIDS and regulation of the CD4+ repertoire during antiviral therapy. Nat Med 4, 215-221.
19. Grau, O., Slizewicz, B., Tuppin, P. & 10 other authors (1995). Association of Mycoplasma penetrans with human immunodeficiency virus infection. J Infect Dis 172, 672-681.
20. Grau, O., Tuppin, P., Slizewicz, B., Launay, V., Goujard, C., Bahraoui, E., Delfraissy, J. F. & Montagnier, L. (1998). A longitudinal study of seroreactivity against Mycoplasma penetrans in HIV-infected homosexual men: association with disease progression. AIDS Res Human Retrovir 14, 661-667.
21. Hansen, J. E., Lund, O., Engelbrecht, J., Bohr, H., Nielsen, J. O. & Hansen, J. E. (1995). Prediction of O-glycosylation of mammalian proteins: specificity patterns of UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase. Biochem J 308, 801-813.
22. Hauschildt, S., Hoffmann, P., Beuscher, H. U., Dufhues, G., Heinrich, P., Wiesmuller, K. H., Jung, G. & Bessler, W. G. (1990). Activation of bone marrow-derived mouse macrophages by bacterial lipopeptide: cytokine production, phagocytosis and Ia expression. Eur J Immunol 20, 63-68.
23. Henrieh, B., Feldmann, R.-C. & Hadding, U. (1993). Cytoadhesins of Mycoplasma hominis. Infect Immun 61, 2945-2951.
24. Herrmann, J. L., O'Gaora, P., Gallagher, A., Thole, J. E. & Young, D. B. (1996). Bacterial glycoproteins: a link between glycosylation and proteolytic cleavage of a 19 kDa antigen from Mycobacterium tuberculosis. EMBO J 15, 3547-3554.
25. Jameson, B. A. & Wolf, H. (1988). The antigenic index: a novel algorithm for predicting antigenic determinants. Comput Appl Biosci 4, 181-186.
26. Krause, D. C. (1996). Mycoplasma pneumoniae cytadherence: unravelling the tie that binds. Mol Microbiol 20, 247-253.
27. Laemmli, U. K. (1970). Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 227, 680-685.
28. Lane, H. C., Masur, H., Edgar, L. C., Whalen, G., Rook, A. H. & Fauci, A. S. (1983). Abnormalities of B-cell activation and immunoregulation in patients with the acquired immunodeficiency syndrome. N Engl J Med 309, 453-458.
29. Le Gall, S., Prevost, M. C., Heard, J. M. & Schwartz, O. (1997). Human immunodeficiency virus type I Nef independently affects virion incorporation of major histocompatibility complex class I molecules and virus infectivity. Virology 229, 295-301.
30. Lemaitre, M., Henin, Y., Destouesse, F., Ferrieux, C., Montagnier, L. & Blanchard, A. (1992). Role of mycoplasma infection in the cytopathic effect induced by human immunodeficiency virus type 1 in infected cell lines. Infect Immun 60, 742-748.
31. Lo, S.-C., Hayes, M. M., Wang, R. Y., Pierce, P. F., Kotani, H. & Shih, J. W. (1991a). Newly discovered mycoplasma isolated from patients infected with HIV. Lancet 338, 1415-1418.
32. Lo, S.-C., Tsai, S., Benish, J. R., Shih, J. W., Wear, D. J. & Wong, D. M. (1991b). Enhancement of HIV-1 cytocidal effects in CD4+ lymphocytes by the AIDS-associated mycoplasma. Science 251, 1074-1076.
33. Lo, S.-C., Hayes, M. M., Tully, J. G., Wang, R. Y., Kotani, H., Pierce, P. F., Rose, D. L. & Shih, J. W. (1992). Mycoplasma penetrans sp. nov. from the urogenital tract of patients with AIDS. Int J Syst Bacteriol 42, 357-364.
34. Ma, J., Gingrich-Baker, C., Franchi, P. M., Bulger, P. & Coughlin, R. T. (1995). Molecular analysis of neutralizing epitopes on outer surface proteins A and B of Borrelia burgdorferi. Infect Immun 63, 2221-2227.
35. Matsushita, K., Nisizawa, T., Nagaoka, S., Kawagoe, M. & Koga, T. (1994). Identification of antigenic epitopes in a surface protein antigen of Streptococcus mutans in humans. Infect Immun 62, 4034-4042.
36. Melchers, F., Braun, V. & Galanos, C. (1975). The lipoprotein of the outer membrane of Escherichia coli: a B-lymphocyte mitogen. J Exp Med 142, 473-482.
37. Milich, D. R., Leroux-Roels, G. G., Louie, R. E. & Chisari, F. V. (1984). Genetic regulation of the immune response to hepatitis B surface antigen (HBsAg). IV. Distinct H-2-linked Ir genes control antibody responses to different HBsAg determinants on the same molecule and map to the I-A and I-C subregions. J Exp Med 159, 41-56.
38. Neyrolles, O., Brenner, C., Prevost M.-C., Fontaine, T., Montagnier, L. & Blanchard, A. (1998). Identification of two glycosylated components of Mycoplasma penetrans: a surface-exposed polysaccharide and a glycolipid fraction. Microbiology 144, 1247-1255.
39. Ogawa, T., Yasuda, K., Yamada, K., Mori, H., Ochiai, K. & Hasegawa, M. (1995). Immunochemical characterisation and epitope mapping of a novel fimbrial protein (Pg-II fimbria) of Porphyromonas gingivalis. FEMS Immunol Med Microbiol 11, 247-255.
40. Pollock, J. M., Douglas, A. J., Mackie, D. P. & Neill, S. D. (1995). Peptide mapping of bovine T-cell epitopes for the 38 kDa tuberculosis antigen. Scand J Immunol 41, 85-93.
41. Sasaki, Y., Blanchard, A., Watson, H. L., Garcia, S., Dulioust, A., Montagnier, L. & Gougeon, M. L. (1995). In vitro influence of Mycoplasma penetrans on activation of peripheral T lymphocytes from healthy donors or human immunodeficiency virus-infected individuals. Infect Immun 63, 4277-4283.
42. Schouls, L. M., van der Heide, H. G. & van Embden, J. D. (1991). Characterization of the 35 kilodalton Treponema pallidum subsp. pallidum recombinant lipoprotein TmpC and antibody response to lipidated and nonlipidated T. pallidum antigens. Infect Immun 59, 3536-3546.
43. Theiss, P., Karpas, A. & Wise, K. S. (1996). Antigenic topology of the P29 surface lipoprotein of Mycoplasma fermentans: differential display of epitopes results in high-frequency phase-variation. Infect Immun 64, 1800-1809.
44. Tully, J. G., Whitcomb, R. F., Clark, H. F. & Williamson, D. L. (1977). Pathogenic mycoplasmas: cultivation and vertebrate pathogenicity of a new spiroplasma. Science 195, 892-894.
45. Wang, R. Y., Shih, J. W., Grandinetti, T., Pierce, P. F., Hayes, M. M., Wear, D. J., Alter, H. J. & Lo, S.-C. (1992). High frequency of antibodies to Mycoplasma penetrans in HIV-infected patients. Lancet 340, 1312-1316.
46. Wang, R. Y., Shih, J. W., Weiss, S. H. & 8 other authors (1993). Mycoplasma penetrans infection in male homosexuals with AIDS: high seroprevalence and association with Kaposi's sarcoma. Clin Infect Dis 17, 724-729.
47. Weigel, L. M., Brandt, M. E. & Norgard, M. V. (1992). Analysis of the N-terminal region of the 47 kilodalton integral membrane lipoprotein of Treponema pallidum. Infect Immun 60, 1568-1576.
48. Wieslander, A., Boyer, M. J. & Wroblewski, H. (1992). Membrane protein structure. In Mycoplasmas: Molecular Biology and Pathogenesis. Edited by J. Maniloff, R. N. McElhaney, L. R. Finch & J. B. Baseman. Washington, DC: American Society for Microbiology.
49. Zheng, X., Lau, K., Frazier, M., Cassell, G. H. & Watson, H. L. (1996). Epitope mapping of the variable repetitive region with the MB antigen of Ureaplasma urealyticum. C.lin Diagn Lab Immunol 3, 774-778.