Obesity and hypertension: From pathophysiology to treatment

International Journal of Obesity

Volumn 23, Issue , 1999, Pages 42-46

  Kolanowski, J ^a  

^a UNIVERSITY OF LOUVAIN MEDICAL SCHOOL   (Belgium)

Author keywords

Hypertension; Obesity; Renal sodium handing; Treatment

Indexed keywords

ANGIOTENSIN; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; CALCIUM; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; INSULIN; METOPROLOL; NEUROPEPTIDE Y; NITRIC OXIDE; NORADRENALIN; SODIUM; THIAZIDE DIURETIC AGENT; TRIACYLGLYCEROL;

BLOOD PRESSURE; BLOOD VESSEL REACTIVITY; CONFERENCE PAPER; EXTRACELLULAR SPACE; HEART OUTPUT; HEMODYNAMICS; HUMAN; HYPERINSULINEMIA; HYPERTENSION; HYPERVOLEMIA; INSULIN RESISTANCE; KIDNEY FUNCTION; KIDNEY MEDULLA; KIDNEY TUBULE ABSORPTION; METABOLIC DISORDER; NATRIURESIS; OBESITY; PATHOPHYSIOLOGY; PHYSICAL ACTIVITY; PRESSOR RESPONSE; PRIORITY JOURNAL; SODIUM ABSORPTION; SODIUM RESTRICTION; TRIACYLGLYCEROL BLOOD LEVEL; VASCULAR ENDOTHELIUM; VASCULAR RESISTANCE; VASCULAR SMOOTH MUSCLE;

ANIMALS; HUMANS; HYPERTENSION; KIDNEY; OBESITY; VASCULAR RESISTANCE; WATER-ELECTROLYTE IMBALANCE;

EID: 0033060597     PISSN: 03070565     EISSN: 14765497     Source Type: Journal    
DOI: 10.1038/sj.ijo.0800794     Document Type: Article

References (38)

1. Hsueh WA, Buchanan TA. Obesity and hypertension. Endocr Metab Clin North Am 1994; 23: 405-427.
2. Hall JE. Renal and cardiovascular mechanisms of hypertension in obesity. Hypertension 1994; 23: 381-394.
3. Van Italie TB. Health implications of overweight and obesity in the United States. Ann Intern Med 1985; 103: 983-988.
4. Tuck ML. Obesity, the sympathetic nervous system, and essential hypertension. Hypertension 1992; 19 (Suppl. 1): S66-S77.
5. Landsberg L. Pathophysiology of obesity-related hypertension: role of insulin and the sympathetic nervous system. J Cardiovasc Pharmacol 1994; 23 (Suppl. 1): S1-S8.
6. Richards RJ, Thakur V, Reisin E. Obesity-related hypertension: its physiological basis and pharmacological approaches to its treatment. J Hum Hypertens 1996; 10 (Suppl. 3): S59-S64.
7. Kolanowski J. Particularités de l’hypertension artérielle associée à l’obésité: de la physiologie à l’approche therapeutique. Rev Frang Endocrinol Clin 1996; 37: 219-224.
8. Kolanowski J, Donckier J. Hypervolaemia is a major determinant of the obesity-related arterial hypertension (Abstract). Int JObes 1997; 21 (Suppl. 2): S91.
9. Hall JE. Mechanisms of abnormal renal sodium handling in obesity hypertension. Am J Hypertens 1997; 10: S49-S55.
10. Reisin E. Sodium and obesity in the pathogenesis of hypertension. Am J Hypertens 1990; 3: 164-167.
11. Cowley AW. Genetic and nongenetic determinants of salt sensitivity and blood pressure. Am J Clin Nutr 1997; 65 (Suppl.): S587-S593.
12. Modan M, Halkin H, Almay S, Lusky A, Eshkil M, Shitrit A, Fuchs A. Hyperinsulinemia: a link between hypertension, obesity and glucose intolerance. J Clin Invest 1985; 75: 809-817.
13. Gans ROB, Toorn L, Bilo HJG, Nauta JJP, Heine RJ, Donker AJM. Renal and cardiovascular effects of exogenous insulin in healthy volunteers. Clin Sci 1991; 80: 219-225.
14. Brands MW, Hall JE, Van Vliet BN, Alonso-Galicia M, Herrera GA, Zappe D. Obesity and hypertension: roles of hyperinsulinemia, sympathetic nervous system and intrarenal mechanisms. J Nutr 1995; 125: 1725S-1731S.
15. Cigolini M, Seidell JC, Charzewska J, Ellsinger M, Dibiase G, Bjorntorp P, Hautvast JGAJ, Contaldo F, Szostak W, Scuro LA. Fasting serum insulin in relation to fat distribution, serum lipid profile, and blood pressure in European women: The European fat distribution study. Metabolism 1991; 40: 781-787.
16. Saad MF, Knowler WC, Pettitt DJ, Nelson RG, Mott DM, Bennett PH. Insulin and hypertension, Relationship to obesity and glucose intolerance in Pima Indians. Diebetes 1990; 39: 1430-1435.
17. Briffeuil P, Huynh-Thu T, Kolanowski J. Reappraisal of the role of insulin on sodium handling by the kidney: effect of intrarenal insulin infusion in the dog. Eur J Clin Invest 1992;22: 523-528.
18. Hall JE, Brands MW, Zappe DH, Alonso-Galicia M. Insulin resistance, hyperinsulinemia, and hypertension: causes, consequences or merely correlations? Proc Soc Exp Biol Med1995; 208: 317-329.
19. Zemel MB. Insulin resistance, obesity and hypertension: an overview. JNutr 1995; 125: S1715-S1717.
20. Rocchini AP. Insulin resistance, obesity and hypertension. J Nutr 1995; 125: S1718-S1724.
21. O’Hare JA. The enigma of insulin resistance and hypertension. Insulin resistance, blood pressure, and the circulation. Am J Med 1988; 84: 505-510.
22. Mark AL, Anderson EA. Genetic factors determine the blood pressure response to insulin resistance and hyperinsulinemia: a call to refocus the insulin hypothesis of hypertension. Proc Soc Exp Biol Med 1995; 208: 330-336.
23. Baron AD, Brechtel G, Johnson A, Fineberg N, Henry DP, Steinberg HO. Interactions between insulin and norepinephrine on blood pressure and insulin sensitivity. J Clin Invest1994; 93: 2453-2462.
24. Wier MR. Insulin resistance and salt sensitivity: a renal hemodynamic abnormality? Am J Hypertens 1996; 9: S193-S199.
25. Majid DSA, Navar LG. Nitric oxide in the mediation of pressure natriuresis. Clin Exp Pharmacol Physiol 1997; 24: 595-599.
26. Schnackenberg C, Patel AR, Kirchner KA, Granger JP. Nitric oxide, the kidney and hypertension. Clin Exp Pharmacol Physiol 1997; 24: 600-606.
27. Clarke J, Benjamin N, Larkin S, Webb D, Maseri A, Davis G. Interaction of neuropeptide Y and the sympathetic nervous system in vascular control in man. Circulation 1991; 83: 774-777.
28. Messaoudi L, Donckier J, Stoffel M, Ketelslegers JM, Kola-nowski J. Changes in blood pressure in vasoactive and volume regulatory hormones during semistarvation in obese subjects. Metabolism 1998; 47: 1-7.
29. Feldman RD, Hramiak IM, Finegood DT, Behme MT. Parallel regulation of the local vascular and systemic metabolic effects of insulin. J Clin Endocrinol Metab 1995; 80: 1556-1559.
30. Steinberg HO, Brechtel G, Johnson A. Fineberg N, Baron AD. Insulin-mediated skeletal muscle vasodilation is nitric oxide dependent: a novel action of insulin to increase nitric oxide release. J Clin Invest 1994; 94: 1172-1179.
31. O-Shaughnessy IM, Myers TJ, Stepniakowski K, Nazarro P, Kelly TM, Hoffmann RG, Egan BM, Kissebach AH. Glucose metabolism in abdominally obese hypertensive and normoten-sive subjects. Hypertension 1995; 26: 186-192.
32. Folli F, Kahn CR, Hansen H, Bouchie JL, Feener EP. Angiotension II inhibits insulin signaling in aortic smooth muscle cells at multiple levels. J Clin Invest 1997; 100: 2158-2169.
33. Tuck ML, Sowers J, Dornfeld L, Kledzik G, Maxwell M. The effect of weight reduction on blood pressure, plasma renin activity and plasma aldosterone levels in obese patients. N Engl J Med 1981; 304: 930-933.
34. Sowers JR, Whitfield LA, Catania RA, Stern N, Tuck ML, Dornfeld L, Maxwell M. Role of sympathetic nervous system in blood pressure maintenance in obesity. J Clin Endocrinol Metab 1982; 54: 1181-1186.
35. Paolisso G, Gambardella A, Verza M, D’Amore A, Sgambato S, Varricchio M. AEC inhibition improves insulin-sensitivity in aged insulin-resistant hypertensive patients. J Hum Hypertens 1992; 6: 175-179.
36. Morel Y, Gradient A, Keller U, Vadas L, Golay A. Insulin sensitivity in obese hypertensive dyslipidemic patients treated with enalapril or atenolol. J Cardiovasc Pharmacol 1995; 26: 306-311.
37. Prisant LM, Carr AA. Antihypertensive drug therapy and insulin resistance. Am J Hypertens 1992; 5: 775-777.
38. Moan A, Risanger T, Eide I, Kjeldsen SE. The effect of angiotensin II receptor blockade on insulin sensitivity and sympathetic nervous system activity in primary hypertension. Blood Pressure 1994; 3: 185-188.