Purine based combinatorial chemistry: Solution phase simultaneous addition of functionalities. Iterative deconvolution by orthogonal protection to a single compound with potent antibacterial activity

Nucleosides and Nucleotides

Volumn 18, Issue 4-5, 1999, Pages 1087-1089

  Fraser, A S ^a   Kawasaki, A M ^a   Cook, P D ^a  

^a ISIS PHARMACEUTICALS   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2,6 DICHLOROPURINE; 2,6 DIPIPERAZINYLPURINE; FUNCTIONAL GROUP; PIPERAZINE DERIVATIVE; PURINE DERIVATIVE; UNCLASSIFIED DRUG;

ALKYLATION; CANDIDA ALBICANS; CONFERENCE PAPER; CONTROLLED STUDY; DRUG STRUCTURE; DRUG SYNTHESIS; ESCHERICHIA COLI; KLEBSIELLA PNEUMONIAE; MINIMUM INHIBITORY CONCENTRATION; PROTECTION; STAPHYLOCOCCUS AUREUS; STREPTOCOCCUS PYOGENES;

CANDIDA ALBICANS; ESCHERICHIA COLI; KLEBSIELLA PNEUMONIAE; STAPHYLOCOCCUS AUREUS; STREPTOCOCCUS PYOGENES;

EID: 0033059374     PISSN: 07328311     EISSN: None     Source Type: Journal    
DOI: 10.1080/15257779908041654     Document Type: Conference Paper

References (2)

1. An, H.; Cummins, L. L.; Griffey, R. H.; Bharadwaj, R.; Haly, B. D.; Fraser, A. S.; Wilson-Lingardo, L.; Risen, L. M.; Wyatt, J. R.; Cook, P. D. J. Am. Chem. Soc. 1997, 119, 3696-3708.
2. An, H.; Haly, B.D.; Fraser, A. S.; Guinosso, C.J.; Cook P.D. J. Org. Chem. 1997, 62, 5156-5164.