Neurotensin-SPDP-poly-L-lysine conjugate: A nonviral vector for targeted gene delivery to neural cells

Molecular Brain Research

Volumn 69, Issue 2, 1999, Pages 249-262

  Martinez Fong, D ^a   Navarro Quiroga, I ^a   Ochoa, I ^a   Alvarez Maya, I ^a   Meraz, M A ^a   Luna, J ^a   Arias Montano, J A ^a  

^a Inst Politecnio Nacional de Mexico   (Mexico)

Author keywords

Gene therapy; Gene transfer; Neurotensin receptor; Receptor mediated endocytosis; Transgenic animal

Indexed keywords

2 [[1 (7 CHLORO 4 QUINOLINYL) 5 (2,6 DIMETHOXYPHENYL) 3 PYRAZOLYL]CARBONYLAMINO] 2 ADAMANTANECARBOXYLIC ACID; CHLORAMPHENICOL ACETYLTRANSFERASE; GREEN FLUORESCENT PROTEIN; NEUROTENSIN; NEUROTENSIN DERIVATIVE; NEUROTENSIN RECEPTOR; POLYLYSINE;

ARTICLE; CELL STRAIN HT29; CONJUGATE; CONTROLLED STUDY; DNA BINDING; ENDOCYTOSIS; EXPRESSION VECTOR; GENE TARGETING; GENE THERAPY; HUMAN; HUMAN CELL; NERVE CELL; NEUROBLASTOMA CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; TRANSGENIC ANIMAL;

ANIMALIA;

EID: 0033058441     PISSN: 0169328X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0169-328X(99)00114-X     Document Type: Article

References (52)

1. S. Amar P. Kitabgi J.P. Vincent Activation of phosphatidylinositol turnover by neurotensin receptors in the human colonic adenocarcinoma cell line HT29 FEBS Lett. 201 1986 31 36
2. S. Amar P. Kitabgi J.P. Vincent Stimulation of inositol phosphate production by neurotensin in neuroblastoma N1E115 cells: implication of GTP-binding proteins and relationship with the cyclic GMP response J. Neurochem. 49 1987 999 1006
3. A. Beaudet J. Mazella D. Nouel J. Chabry M.N. Castel P. Laduron P. Kitabgi M.P. Faure Internalization and intracellular mobilization of neurotensin in neuronal cells Biochem. Pharmacol. 47 1994 43 52
4. J.M. Botto J. Chabry P. Sarret J.P. Vincent J. Mazella Stable expression of the mouse levocabastine-sensitive neurotensin receptor in HEK 293 cell line: binding properties, photoaffinity labeling, and internalization mechanism Biochem. Biophys. Res. Commun. 243 1998 585 590
5. E.G. Cape A. Alonso A. Beaudet E. Jones Neurotensin microinjections into the basal forebrain promote cortical activation associated with the states of wake and ps in the rat Soc. Neurosci. Abstr. 22 1996 64.17
6. J. Carlsson H. Drevin R. Axén Protein thiolation and reversible protein–protein conjugation. N -succinimidyl-3-(2-pyridyldithio)propionate, a new heterobifunctional reagent Biochem. J. 173 1978 723 737
7. M.N. Castel C. Malgouris J.C. Blanchard P.M. Laduron Retrograde axonal transport of neurotensin in the dopaminergic nigrostriatal pathway in the rat Neuroscience 36 1990 425 430
8. M.N. Castel D. Faucher F. Cuiné P. Dubédat A. Boireau P.M. Laduron Identification of intact neurotensin in the substantia nigra after its retrograde axonal transport in dopaminergic neurons J. Neurochem. 56 1991 1816 1818
9. M.N. Castel J. Woulfe X. Wang P.M. Laduron A. Beaudet Light and electron microscopic localization of retrogradely transported neurotensin in rat nigrostriatal dopaminergic neurons Neuroscience 50 1992 269 282
10. M.N. Castel A. Beaudet P.M. Laduron Retrograde axonal transport of neurotensin in rat nigrostriatal dopaminergic neurons. Modulation during ageing and possible physiological role Biochem. Pharmacol. 47 1994 53 62
11. J. Chabry G. Gaudriault J.P. Vincent J. Mazella Implication of various forms of neurotensin receptors in the mechanism of internalization of neurotensin in cerebral neurons J. Biol. Chem. 268 1993 17138 17144
12. M. Chalfie Y. Tu G. Euskirchen W.W. Ward D.C. Prasher Green fluorescent protein as a marker for gene expression Science 263 1994 802 805
13. M.J. Cooper Noninfectious gene transfer and expression systems for cancer gene therapy Semin. Oncol. 23 1996 172 187
14. A.J. Cumber J.A. Forrester B.M. Foxwell W.C. Ross P.E. Thorpe Preparation of antibody-toxin conjugates Methods Enzymol. 112 1985 207 225
15. G. Daukas S.H. Zigmond Inhibition of receptor-mediated but not fluid-phase endocytosis in polymorphonuclear leukocytes J. Cell. Biol. 101 1985 1673 1679
16. M. Goedert K. Pittaway P.C. Emson Neurotensin receptors in the rat striatum: lesion studies Brain Res. 299 1984 164 168
17. C.M. Gorman L.F. Moffat B.H. Howard Recombinant genomes which express chloramphenicol acetyltransferase in mammalian cells Mol. Cell. Biol. 2 1982 1044 1051
18. F.L. Graham A.J. van der Eb A new technique for the assay of infectivity of human adenovirus 5 DNA Virology 52 1973 456 467
19. D. Gully M. Canton R. Boigegrain F. Jeanjean J.C. Molimard M. Poncelet C. Gueudet M. Heaulme R. Leyris A. Brouard D. Pelaprat C. Labbé-Jullié J. Mazella P. Soubrié J.P. Maffrand W. Rostène P. Kitabgi G. LeFur Biochemical and pharmacological profile of a potent and selective nonpeptide antagonist of the neurotensin receptor Proc. Natl. Acad. Sci. U.S.A. 90 1993 65 69
20. W.H. Günzburg B. Salmons Development of retroviral vectors as safe, targeted gene delivery systems J. Mol. Med. 74 1996 171 182
21. R. Heim A.B. Cubitt R.Y. Tsien Improved green fluorescence [letter] Nature 373 1995 663 664
22. J.E. Heuser R.G. Anderson Hypertonic media inhibit receptor-mediated endocytosis by blocking clathrin-coated pit formation J. Cell. Biol. 108 1989 389 400
23. G. Jung W. Köhnlein G. Lüders Biological activity of the antitumor protein neocarzinostatin coupled to a monoclonal antibody by N -succinimidyl 3-(2-pyridyldithio)-propionate Biochem. Biophys. Res. Commun. 101 1981 599 606
24. P.G. Kennedy Potential use of herpes simplex virus (HSV) vectors for gene therapy of neurological disorders Brain 120 1997 1245 1259
25. P. Kitabgi W. Rostène M. Dussaillant A. Schotte P.M. Laduron J.P. Vincent Two populations of neurotensin binding sites in murine brain: discrimination by the antihistamine levocabastine reveals markedly different radioautographic distribution Eur. J. Pharmacol. 140 1987 285 293
26. D.L. Knoell I.M. Yiu Human gene therapy for hereditary diseases: a review of trials Am. J. Health Syst. Pharm. 55 1998 899 904
27. C. Labbé Jullié S. Barroso D. Nicolas-Etève J.L. Reversat J.M. Botto J. Mazella J.M. Bernassau P. Kitabgi Mutagenesis and modeling of the neurotensin receptor NTR1. Identification of residues that are critical for binding SR 48692, a nonpeptide neurotensin antagonist J. Biol. Chem. 273 1998 16351 16357
28. O.H. Lowry N.J. Rosebrough A.L. Farr R.J. Randall Protein measurement with the folin phenol reagent J. Biol. Chem. 193 1951 265 275
29. D. Martinez-Fong J.E. Mullersman A.F. Purchio J. Armendariz-Borunda A. Martinez-Hernandez Nonenzymatic glycosylation of poly- l -lysine: a new tool for targeted gene delivery Hepatology 20 1994 1602 1608
30. 11]neurotensin, a highly radioactive ligand of neurotensin receptors. Preparation, biological activity, and binding properties to rat brain synaptic membranes J. Biol. Chem. 258 1983 3476 3481
31. J. Mazella J.M. Botto E. Guillemare T. Coppola P. Sarret J.P. Vincent Structure, functional expression, and cerebral localization of the levocabastine-sensitive neurotensin/neuromedin N receptor from mouse brain J. Neurosci. 16 1996 5613 5620
32. J. Mazella N. Zsurger V. Navarro J. Chabry M. Kaghad D. Caput P. Ferrara N. Vita D. Gully J.P. Maffrand J.P. Vincent The 100-kDa neurotensin receptor is gp95/sortilin, a non-G-protein-coupled receptor J. Biol. Chem. 273 1998 26273 26276
33. A. Mazin T. Timchenko J. Menissier-de Murcia V. Schreiber J.F. Angulo G. de Murcia R. Devoret Kin17, a mouse nuclear zinc finger protein that binds preferentially to curved DNA Nucleic Acids Res. 22 1994 4335 4341
34. P. Midoux C. Mendes A. Legrand J. Raimond R. Mayer M. Monsigny A.C. Roche Specific gene transfer mediated by lactosylated poly- l -lysine into hepatoma cells Nucleic Acids Res. 21 1993 871 878
35. D. Nouel M.P. Faure J.A. St. Pierre R. Alonso R. Quirion A. Beaudet Differential binding profile and internalization process of neurotensin via neuronal and glial receptors J. Neurosci. 17 1997 1795 1803
36. C.M. Petersen M.S. Nielsen A. Nykjaer L. Jacobsen N. Tommerup H.H. Rasmussen H. Roigaard J. Gliemann P. Madsen S.K. Moestrup Molecular identification of a novel candidate sorting receptor purified from human brain by receptor-associated protein affinity chromatography J. Biol. Chem. 272 1997 3599 3605
37. J.L. Sadoul J. Mazella S. Amar P. Kitabgi J.P. Vincent Preparation of neurotensin selectively iodinated on the tyrosine 3 residue. Biological activity and binding properties on mammalian neurotensin receptors Biochem. Biophys. Res. Commun. 120 1984 812 819
38. J. Sambrook, E.F. Fritsch, T. Mantiatis, Molecular cloning, a laboratory manual, 2nd edn., Cold Spring Harbor Laboratory Press, 1989.
39. P. Sarret A. Beaudet J.P. Vincent J. Mazella Regional and cellular distribution of low affinity neurotensin receptor mRNA in adult and developing mouse brain J. Comp. Neurol. 394 1998 344 356
40. 3 H ]neurotensin binding site in rat brain Naunyn-Schmiedebergs Arch. Pharmacol. 333 1986 400 405
41. C.P. Simkevich J.P. Thompson H. Poppleton R. Raghow The transcriptional tissue specificity of the human proα1 (I) collagen gene is determined by a negative cis -regulatory element in the promoter Biochem. J. 286 1992 179 185
42. M.A. Spear U. Herrlinger N. Rainov P. Pechan R. Weissleder X.O. Breakefield Targeting gene therapy vectors to CNS malignancies J. Neurovirol. 4 1998 133 147
43. R. Steinberg I. Bougault J. Souilhac D. Gully G. Le Fur P. Soubrié Blockade of neurotensin receptors by the antagonist SR 48692 partially prevents retrograde axonal transport of neurotensin in rat nigrostriatal system Neurosci. Lett. 166 1994 106 108
44. R. Steinberg D. Rodier G. Mons D. Gully G. Le Fur P. Soubrie SR 48692-sensitive neurotensin receptors modulate acetylcholine release in the rat striatum Neuropeptides 29 1995 27 31
45. N. Vita P. Laurent S. Lefort P. Chalon X. Dumont M. Kaghad D. Gully G. Le Fur P. Ferrara D. Caput Cloning and expression of a complementary DNA encoding a high affinity human neurotensin receptor FEBS Lett. 317 1993 139 142
46. K. Weis U. Ryder A.I. Lamond The conserved amino-terminal domain of hSRP1 alpha is essential for nuclear protein import EMBO J. 15 1996 1818 1825
47. G.Y. Wu C.H. Wu Evidence for targeted gene delivery to Hep G2 hepatoma cells in vitro Biochem. 27 1988 887 892
48. G.Y. Wu C.H. Wu Receptor-mediated gene delivery and expression in vivo J. Biol. Chem. 263 1988 14621 14624
49. C.H. Wu J.M. Wilson G.Y. Wu Targeting genes: delivery and persistent expression of a foreign gene driven by mammalian regulatory elements in vivo J. Biol. Chem. 264 1989 16985 16987
50. G.Y. Wu J.M. Wilson F. Shalaby M. Grossman D.A. Shafritz C.H. Wu Receptor-mediated gene delivery in vivo. Partial correction of genetic analbuminemia in Nagase rats J. Biol. Chem. 266 1991 14338 14342
51. G.Y. Wu C.H. Wu Targeted delivery and expression of foreign genes in hepatocytes Targeted Diagn. Ther. 4 1991 127 149
52. G.Y. Wu C.H. Wu Delivery systems for gene therapy Biotherapy 3 1991 87 95